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3039 Cat: Echocardiography: TEE and 3D HEART FAILURE RELATED TO CONSTRICTIVE AND RESTRICTIVE CARDIOMYOPATHY: ASSESSMENT BY ECHOCARDIOGRAPHY A.M. Amanullah Jefferson Medical College of Thomas Jefferson University, Einstein Healthcare Network, Philadelphia, PA, USA Constrictive pericarditis and restrictive cardiomyopathy are 2 forms of diastolic heart failure that might have similar clinical presentations. The differentiation of these 2 disorders is crucial because constrictive pericarditis can potentially be cured by pericardiectomy, whereas restrictive cardiomyopathy is usually treated symptomatically. Spectral Doppler echocardiography is a useful tool for diagnosing constrictive pericarditis and differentiating it from restrictive cardiomyopathy. Although both conditions can show any of the different phases of restriction on conventional Doppler measurement of the mitral inflow, respiratory changes of mitral inflow are quite different in these 2 conditions. Because the myocardium is isolated from the intrathoracic respiratory pressure changes in constrictive pericarditis, there are significant flow changes over the mitral and tricuspid valves during inspiration and expiration. During inspiration, the pulmonary capillary pressure drops, whereas the intracardiac pressure is not affected; therefore, the inflow to the left ventricle over the mitral valve is reduced in constrictive pericarditis. On the other hand, the flow over the tricuspid valve increases during inspiration. All these can be visualized by Doppler echocardiography over the mitral and tricuspid valve with simultaneous graphic recording of the phases of respiration. The interventricular septum will also show a leftward shift during early diastole under inspiration, due to ventricular interdependence resulting from encasement of the heart in the rigid pericardium shell. These techniques have been found to be reasonably sensitive and specific for the diagnosis of constrictive cardiomyopathy. Tissue Doppler and color M-mode echocardiography are also highly sensitive and specific in the differential diagnosis of these two entities. In restrictive cardiomyopathy, mitral E’velocity is reduced, whereas it is normal or elevated in constrictive pericarditis. Also color M-mode echocardiography has a high diagnostic accuracy for the diagnosis of constrictive cardiomyopathy and differentiating it from restrictive cardiomyopathy.