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Understanding Cancer Names______Meghan T. and Ashley S.__________ Section 1: Factors Reported to Be Associated with Cancer Visit http://science.education.nih.gov/supplements/nih1/Cancer/activities/activity2_videos.htm to fill out the following chart. View the News Alert videos and use the information provided to identify what each video suggests is the cause of cancer and what evidence supports that claim. News Alert Video Cancer and Chemical Poisons Cancer and Your Family History Cancer and Radiation Exposure Cancer and UV Light Factor Proposed to Cause Cancer Chimney sweepers have a chance to get cancer from their job Evidence The coal and ash can flame up and cause a cancer burn. Example: Lung Cancer A boy had cancer in his eye and was cured and had seven children but two of the girls got that same cancer and died three months later. The cancer can be transmitted from parents to children or family generations just like hair and eye color can. Technicians have a high rate of getting Skin cancer from the rays they are exposed to. While the one’s being x-rayed are not as likely since they are not exposed as oftenly. They are exposed to them for many hours. Advice is said that the technicians should turn the machine off when adjusting them and when they are recharging they should leave the room. The sun because of the UV-rays causes the cancer and burns. Not enough sunscreen and a different swim suit that shows off more skin can cause the burns and then lead to cancer. Section 2: Building an Explanation for the Cause of Cancer View the animations on the website by clicking on “cell cycle animations.” Think about the information each animation presents. Then, write a one-sentence statement for each that summarizes what you learned. Animation 1: Cancer involves . . . when a cell breaks off and does its own thing and divides too much. It involves the cells and then can cause cancers Animation 2: Cell division normally is . . . a cell cycle clock- goes from g1 (growth) to s (protein synthesis) to g2 (DNA replication) then goes to mitosis checkpoint. Animation 3: Cell cycle regulation is accomplished by . . . genes- such as proto-oncogene- encourage cell division and tumor suppressor genes- act as a stimulator to grow and divide. Animation 4: Cancer-causing agents often . . . can also change the DNA (mutations), powerful mutagens- cause mutations. Animation 5: When damage occurs to genes that regulate the cell cycle . . . proto-oncogenes can then change to just oncogenes which are one that stimulate excessive cell division. And the tumor suppressor genes become inactive. Section 3: Explaining Factors Associated with Cancer Review your notes from Section 1. Then, write a sentence that describes how our current understanding of cancer explains the role that each factor plays in causing cancer. Cancer and Chemical Poisons Cancer and Your Family History Cancer and Radiation Exposure Cancer and UV Light Section 4: How does chemotherapy work? Visit http://www.enile.co.uk/portfolio/cancer/lymph03.html to answer the following question. Describe the three types of chemotherapy that are featured in this animation.