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Evidence for Ancestry Name Part I: The picture below shows the forelimbs of mammals and how the bone structures are similar. Follow the instructions for coloring and then answer the questions on the next page. Coloring Instruction: Humerus)- Orange Radius - Yellow Ulna - Green Carpals - Blue Metacarpals- Purple Phalanges - Brown Part I Questions: 1. What is the common function of all these forelimbs? Mobility, move around, bend 2. Describe at least one similarity in the structure of mammalian forelimbs. Humerus, carpal, radius, ulna, phalanges 3. How do these similarities support the evidence of ancestry? It shows that many species have common physical features but have adapted to their environments Part II: The picture shows embryonic development of several. Use it to answer the questions below. Eye Auditory Vesicle Gill Slits Tail Notochord (becomes spinal cord /vertebrae) Part II Questions: 4. At which stage is it the most difficult to tell the embryos apart? (I, II, or III) I 5. Describe at least one similarity in the structure of these embryos Eyes, spinal cord, begin life with a tail 6. How do these similarities support the evidence of ancestry? The embryo begins with very similar characteristics showing that they have a common ancestor Part III: Examining the relationships between biological molecules, such as proteins or DNA can tell scientists how closely related organisms are. The more similar these molecules are, the more recently the organisms had a common ancestor. Follow the directions for each table. 1. There are 146 amino acids in the protein hemoglobin. This table shows a portion of the amino acid sequence for hemoglobin for 6 different mammals. Circle or highlight the amino acids in the chimp, gorilla, monkey, horse, and kangaroo sequences that differ from those in the human sequence. Amino Acid # Human Chimp Gorilla Rhesus Monkey Horse Kangaroo Amino Acid # Human Chimp Gorilla Rhesus Monkey Horse Kangaroo 2. 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 thr thr thr leu leu leu ser ser ser glu glu glu leu leu leu his his his cys cys cys asp asp asp lys lys lys leu leu leu his his his val val val asp asp asp pro pro pro glu glu glu gln leu ser glu leu his cys asp lys leu his val asp pro glu ala lys leu leu ser ser glu glu leu leu his his cys cys asp asp lys lys leu leu his his val val asp asp pro pro glu glu 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 asn asn asn asn asn asn phe phe phe phe phe phe arg arg lys lys arg lys leu leu leu leu leu leu leu leu leu leu leu leu gly gly gly gly gly gly asn asn asn asn asn asn val val val val val ile leu leu leu leu leu ile val val val val ala val cys cys cys cys leu ile val val val val val cys leu leu leu leu val leu ala ala ala ala ala ala his his his his arg glu The table shows the number of amino acids in cytochrome c that differ between several organisms and humans. Cytochrome c is a protein found in mitochondria. It is often studied because most organisms have mitochondria and therefore they have cytochrome c. Rewrite the information in the blank table by listing the organisms IN ORDER with the greatest number of differences at the top and the least at the bottom. Species Comparison Human—chimp Human—fruit fly Human—horse Human—pigeon Human—rattlesnake Human—red bread mold Human—rhesus monkey Human—screwworm fly Human—snapping turtle Human—tuna Human—wheat # of differences 0 29 12 12 14 48 1 27 15 21 43 Species Comparison Human—red bread mold Human—wheat Human—fruit fly Human—screwworm fly Human—tuna Human—snapping turtle Human—rattlesnake Human—pigeon Human—horse Human—rhesus monkey Human—chimp Part IV Questions: Use all of the above tables to answer the questions below. 7. On the basis of hemoglobin similarity, which organism appears to be most closely related to humans? least related? Closely related = human and chimp Least closely related = human and kangaroos 8. On the basis of cytochrome c similarity, which organism appears to be most closely related to humans? least related? Closely related = human and chimp Least closely related = human and red bread mold 9. If the amino acids sequences in the proteins of two organisms are similar, why will their DNA also be similar? Amino acid sequences are determined by nucleotide sequences in the DNA DNA contains the key for RNA which then codes the proteins # of differences 48 43 29 27 21 15 14 12 12 1 0
