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Hereditary Cancer Syndromes 1. IntelligeneDx is a CLIA certified Oncogenomics Laboratory located in the Kansas Bioscience Park in Olathe, Kansas. 2. Technology Platform: Illumina, which has a Q30 score for accuracy that is top in the industry (Error rate: 1/1000). 3. CompleteRisk – the most comprehensive test for identifying hereditary cancers – a total of 94 genes. 4. TAT: 2-3 weeks with a team in place to manage communication between the lab and customers. 5. Clear communication plan with patients to discuss financial obligations. We have a patient-friendly billing policy (included in packet). All patients should receive guidance on billing at the point of care. In addition, commercially insured patients will be contacted to discuss any out of pocket responsibilities prior to testing the sample. 6. All variants found in the genes tested are uploaded to an international database and every 3 months are checked to verify if there is any change in its status. We recommend the patient to contact IntelligeneDx once a year to verify if there is any reclassification of the variant found in his/her analysis. 7. Genetic Counselor on site and remote; Immediate access to Onco-geneticists for peer-to-peer discussion. 8. Customized Onco-geneticist overlay accompanies each test report, there are guideline-based recommendations noted for any positive mutations. 9. Sample collection options are saliva, blood or mouthwash. 10. Screening Questionnaire and Physician Checklist provided to identify high-risk patients who need diagnostic testing for hereditary cancer syndromes. Our goal is to offer affordable testing for your patients to identify those with a high risk for developing a hereditary cancer syndrome. It is not to replace anything you are currently doing to screen for cancer but only to enhance their preventative treatment plan. 10900 S Clay Blair Blvd., Suite 1400 Olathe, KS 66061 © All rights reserved (913) 258 2300 www.intelligenedx.com