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SESAME STREET GENETICS ACTIVITY Introduction: It is an exciting time for geneticists as they have just discovered the genome for Sesamus muppetis (Sesame Street characters). They have determined that Sesame Street characters have six chromosomes. On these chromosomes they have found specific locations of the following genes: eye shape, nose color, body color, hair type, blood type, fingers, toes and certain genetic disorders. Due to your expertise in the genetics area they have hired you as their apprentice to finish the job. Your task: 1) Research traits of specific Sesame Street characters and identify their genotypes and matching phenotypes. 2) Marry your assigned Sesame Street characters and identify their genetic profile. 3) Determine the probability of their children’s traits using Punnett squares. 4) Create two Sesame Street Muppet children using your Punnett square probability and fill out a children’s profile for each. 5) Complete your family pedigree. 6) Draw your Sesame Street family portrait, including a list of family members, genetic make-up and monster profile of children. Checklist: Your performance will be assessed based on the accurate completion of several assignments. To mark your progress, use the following checklist. Check off each task as completed Task Task 1: Task 2: Task 3: Task 4: Task 5: Task 6: Traits (genotypes and phenotypes) of each Sesame Street Character Muppet Monster Mates Genetic Profile Sesame Street Punnett Squares (genotypes, phenotypes and probabilities) Muppet Monster Children Worksheet (genotypes/phenotypes and profiles) Family Pedigree Draw Sesame Street Family Portrait Rubric: Category Genetic Profiles Punnett Squares Pedigrees Family Portrait Requirements Point Value 25 Accurately completed genetic profiles (genotypes and phenotypes) Accurately drawn Punnett squares with correct 25 genotypes, phenotypes and percentages. Diagram appropriately arranged for pedigree, includes 25 generations and numbered individuals; correct symbols, shading and carriers. Accurate, creative, neat and colorful representation of 25 family. Total Points Earned Points Earned TASK 1: GENETIC TRAITS Instructions: Fill in the genotypes based on the phenotypes below. Be sure to refer to the Muppet profiles and Table 1.1. GENOTYPES TABLE Eye Shape Nose Color Body Color Hair Type Blood Type Toes Fingers Eye Shape Nose Color Body Color Hair Type Blood Type Toes Fingers Flat Pink Blue Hairy AB No Yes Pops Out Orange Red Hairy A No Yes Pops Out Pink Orange Hairy B No Yes Pops Out Orange Magenta Hairy O Yes Yes Pops Out Yellow Pink Hairy A No No Pops Out Orange Teal Hairy A Yes Yes Pops Out No Nose Blue Hairy B Yes Yes Flat Pink Pink Hairy A Yes Yes Grover Elmo Zoe Telly Honker Rosita Cookie Monster Abby PHENOTYPES TABLE Grover Elmo Zoe Telly Honker Rosita Cookie Monster Abby TASK 2: MUPPET MATES GENETIC PROFILES _________________ (Male Muppet’s Name) Characteristic Phenotype Genotype Type of Inheritance Genotype Type of Inheritance Eye shape Nose Color Body Color Hair Type Blood Type Toes Fingers ________________ (Female Muppet’s Name) Characteristic Eye shape Nose Color Body Color Hair Type Blood Type Toes Fingers Phenotype TASK 3: SESAME STREET PUNNETT SQUARES Complete the Punnett squares to determine the possible traits of the Muppet children. Indicate the probability for each genotype and phenotype. Gender X Y Hair Type X X Genotypes & Percentages: Genotypes & Percentages: Phenotypes & Percentages: Phenotypes & Percentages: Eye Shape Toes Genotypes & Percentages: Genotypes & Percentages: Phenotypes & Percentages: Phenotypes & Percentages: Nose Color Fingers Genotypes & Percentages: Genotypes & Percentages: Phenotypes & Percentages: Phenotypes & Percentages: Body Color Blood Type Genotypes & Percentages: Genotypes & Percentages: Phenotypes & Percentages: Phenotypes & Percentages: TASK 4: MUPPET MONSTER CHILDREN Now that you have crossed your Muppets, create two Muppet monster children. Use a paperclip spinner to determine the traits for both children. Name your Muppet monster children and predict their profiles as they grow older. Be creative! Name of Muppet Monster Child #1 _______________ Characteristic Eye shape Nose Color Body Color Hair Type Blood Type Toes Fingers Birthday Age Best Friend Philosophy Favorite Quote Other Phenotype Genotype Type of Inheritance Probability of Trait Name of Muppet Monster Child #2 _______________ Characteristic Phenotype Genotype Type of Inheritance Probability of Trait Eye shape Nose Color Body Color Hair Type Blood Type Toes Fingers Birthday Age Best Friend Philosophy Favorite Quote Other TASK 5: SESAME STREET PEDIGREE Use the Muppet family profiles for each Muppet in your married couple to create a family pedigree on a separate sheet of paper. TASK 6: SESAME STREET FAMILY PORTRAIT Draw a family portrait that includes your Muppet couple and the two Muppet children on a separate sheet of paper.