Download UME Reference Materials Lab

TÜBİTAK
REFERENCE MATERIALS LABORATORY
CHEMISTRY GROUP
REFERENCE MATERIALS LABORATORY
Gebze, Kocaeli, TURKEY
TÜBİTAK UME Reference Materıals Laboratory
TÜBİTAK
Our Aim
Giving the first priority to the needs of the Turkish
laboratories, we want to produce and certify
reference materials in the fields of food safety,
environmental and clinical analysis which will
inrease the measurement quality, reliability and
as a consequence increase the quality of life.
Other Activities
• Organizing
Proficiency Tests
• Supplying Training in the field of Chemical Metrology
TÜBİTAK UME Chemistry Group
Reference Material Production and Certification Organisation
ISO CLASS 4, 5, 6 CLEAN LAB.
HIGH RES. ICP MS
QQQ- ICP MS
Q-ICP MS
AAS (GF, HG)
ION CHROMATOGRAPHY
LASER ABLATION
MW DIGESTION
PRIMARY PH MEASUREMENT
(HARNED CELL)
HIGH ACCURACY COULOMETER
POTENTIOSTAT/GALVANOSTAT
NANOVOLTMETER
ELECTROLYTIC CONDUCTIVITY METER
VARIABLE TRANSFORMER
NMR (600 MHz)
LC-MS/MS
GC-MS/MS
IR-MS
Q-TOF LC-MS/MS
MALDI-TOF MS
MICRO-TOFQ LC-MS/MS
TSQ GC/MS
HIGH RES. TOF MS
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DIGITAL PCR (DPCR)
REAL TIME PCR (QPCR)
NANODROP
SPECTROPHOTOMETER
FLOW CYTOMETRY
FLORECENCE MICROSCOPE
TISSUE HOMOGENIZER
DNA GEL ELECTROPHORESIS
CENTIFUGES, INCUBATORS
Trainings
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8 TÜBİTAK UME researchers were trained for a year on
• CRM Production,
• Certification and
• Primary Reference Measurement Techniques such
as ID-ICP MS
between years 2009-2012
in EU - JRC – IRMM, Belgium.
RM Laboratory Infrastructure
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Analytical Instruments
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Particle Size Analyser (Laser Diffraction)
Particle Size Analyser (Vibratory Sieve)
Particle Size Analyser (Air Jet Sieve)
Karl Fischer (Coulometric) Water Content Analyser
UPLC (with DAD and FLD dedectors) System
Various Balances (60 kg/d: 1g, 10 kg/d:1mg, 520 g/d:0.1mg)
RM Laboratory Infrastructure
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Material Processing
Various Crushers and Mills:
Cryogenic vibrating mill,
Roll mill,
Variable speed rotating mill,
Jaw crusher, Disc mill,
Planetary ball mill, mortar mill,
universal cutting mill
RM Laboratory Infrastructure
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Material Processing
Vacuum Blender
Sieving Systems
Various Mixers
(V-Type (150 L), 3-Dimensional (2, 20 and 350 L capacity)
Vibratory Feeder and Sample Divider
Lyophilizers (Production Scale [3.9 m2 shelf area] and Pilot Scale [0.6 m2shelf area])
Powder Filling Machine
Liquid Filling, Capping and Labelling Machine
Vacuum Sachet Machine
RM Laboratory Infrastructure
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Material Processing, Storage, Testing
Water Purification System
Liquid Homogenisation System 200 L
Raw material storage rooms (-20, +4°C)
Product storage Rooms (-20, +4 and +18 °C)
Freezers (-86 and -20 °C)
Storage Cabinets (+4°C)
Climatic Test Chambers
Reference Material Projects (Internal Funding)
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Completed Projects (Products on Sale)
UME CRM 1301 Chloramphenicol Primary Calibrant (On sale)
UME CRM 1201Elements in Spring Water (On Sale)
UME CRM 1308 Vitamin D in Serum-Lyophlized (On Sale)
UME CRM 1203-1&2 Sulfur in Diesel,Two Levels (On Sale)
UME RM 9901 Total Contamination in Diesel (On Sale)
UME RM 9902 Protein in Wheat Flour (On Sale)
Ongoing Projects
 Aflatoxins in Dried Fig (in Certification Stage)
 Trace Elements in Hazelnut (in Certification Stage)
 Carbon Isotope Ratio Reference Materials (in Certification Stage)
 pH Buffer Solutions for measurement and calibration (in Certification Stage)
 Multiparameter in Diesel (in Certification Stage)
 Elements in Waste Water (in Certification Stage)
http://www.ume.tubitak.gov.tr/en/laboratuvarlarimiz/reference-materials-laboratory
Clinical Measurements
Reference Material Project (External Funding)
TÜBİTAK
Ongoing Project
 TUBITAK ARDEP 1003 Project:
Development and Production of Certified Reference Materials and Quality Control Materials for
Newborn Screening and Measurements Routinely Performed by Clinical Biochemistry Labs for
Amino Acids and Organic Acids
(0.8 MEUR, 36 Months).
Candidate CRMs & RMs:
• UME CRM 1314- Target: 52 Amino Acids in human plazma,
• UME CRM 1315- Target: 53 Organic acids in urine
• Quality control materials (RMs) at different levels will also be produced within the scope of the project
.
Environmental Measurements
Reference Material Project (External Funding)
TÜBİTAK
Recently Started Project
 EMPIR Call 2014 -14-RPT-03-ENVCRM
Matrix Reference Materials for Environmental Analysis
A consortium of 9 partners (NMI’s, DI’s, Universities) from 8 Europian countries will be coordinated by TÜBİTAK
UME to produce certified reference materials [inorganics (Elements) in water &soil and organics e.g.: PFOS) in
water]. Strategies for sustainable production of environmental reference materials according to the needs of end
users will also be seeked (0.5 MEUR, 36 Months).
3 Candidate CRMs: Elements in Water (Waste), Elements in Soil, Organic Pollutants (PFOS, PFOA) in Water
Photos From Reference Material Production
TÜBİTAK
Aflatoxins in Dry Fig Project Reference Material Production
Chloramphenicol Primary Calibrant Reference Material Production
Photos From Reference Material Production
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Elements in Hazelnut Project Reference Material Production
Other Services (Proficiency Tests, Trainings, Tests)
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ENVIRONMENTAL PROFICIENCY TESTS
Elements in Drinking Water (Ag, Al, As, B, Ba, Cd, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Sb, Se, Zn)
Anions in Drinking Water (floride, phosfate, chloride, nitrate, nitrite and sulfate)
Cations in Water (Ca, Mg, Na, K and ammonium)
Suspended Solids in Water
pH in Water
Electrical Conductivity in Water
Metals in Waste Water( As, Cd, Cr, Cu, Fe, Hg, Ni, Pb, Zn)
COD in Waste Water
Elements in Waste Oil ( As, Cd, Cr, Pb)
Elements in Soil ( As, B, Ca, Cd, Co, Cr, Cu, Fe, Mg, Mn, Ni, Pb, Sb, Zn)
pH in Soil
Electrical Conductivity in Soil
FUEL PROFICIENCY TESTS
Gasoline
Diesel
Fuel-Oil
Jet-A1
FOOD PROFICIENCY TESTS
TRAININGS
HMF, Glucose, Fructose, Sucrose in Honey
(13C/12C) Isotope Ratio in Honey
Refractive Index, Peroxide Value and Iodine Number in Sunflower Oil
Determination of Fatty Acids Composition of Sunflower Oil
Benzoate and Sorbate in Ketchup
Sulfur Dioxide (SO2) in Dry Apricot
Aflatoxin in food
Moisture, Ash, Fat and Protein in Food
Metals in Tomato Paste (Cd, Cu, Fe, Pb, Zn ve Sn)
Method Validation
Measurement Uncertainty in Chemical
Measurements
Special Trainings on Demand
http://www.ume.tubitak.gov.tr/en/hizmetlerimiz/industrial-services
Thank You
TÜBİTAK