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Ocular Histoplasmosis Syndrome Ocular Histoplasmosis Syndrome is a growth in abnormal blood cells under the retina induced by exposure to a particular kind of histo fungus. The syndrome affects the part of the retina responsible for close, sharp vision deteriorates and eventually, without treatment it can lead to complete blindness. Ocular histoplasmosis syndrome usually affects patients aged 20-50 years; the average age is 35 years. Risk Factors of the Syndrome Histoplasmosis Syndrome Histoplasmosis is a disease caused when airborne spores of the fungus Histoplasma capsulatum are inhaled into the lungs. Mild cases can later cause ocular histoplasmosis syndrome a leading cause of vision loss in Americans ages 20 to 40. droppings. High risk groups are immunocompromised persons Approx. 80% of population living in areas with endemic disease are skin-test positive for the histoplasmosis syndrome. Of HIV-infected persons in these areas, 10% - 25% develop disseminated histoplasmosis. Treatment Treatments vary from medication to surgery. References: Curtiss, M. (2005). Ocular histoplasmosis syndrome: the science versus the experience. Retrieved from http://serendip.brynmawr.edu/exchange/node/1762 Emedicine. (2010, February 10). Presumed ocular histoplasmosis syndrome. Retrieved from http://emedicine.medscape.com/article/1224400overview National Eye Institute. (2010, February). Histoplasmosis. Retrieved from http://www.nei.nih.gov/health/histoplasmosis/index.a sp The National Institute of Allergy and Infectius Diseases. (2010). Histoplasmosis and the eye. Retrieved from http://www.medhelp.org/nihlib/GF13.html Wrong Diagnosis. (n.d.). Histoplasmosis dbmd. Retrieved from http://www.wrongdiagnosis.com/artic/histoplasmosis _dbmd.htm Certain U.S. States Individuals living in certain states that have a high prevalence of histoplasmosis exposure are also more likely to contract the disease. Areas with Endemic Disease Persons in areas with endemic with exposures to accumulations of bird or bat