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3rd European Section Meeting of the International
Academy of Cardiovascular Sciences (IACS)
1-4 October, 2016
FINAL ANNOUNCEMENT
In 2016, the 3rd European Section Meeting of the International Academy of Cardiovascular Sciences
(IACS) coincides with the 20th Anniversary of the founding of the International Academy of Cardiovascular
Sciences by Professor Naranjan Dhalla. On this very special occasion, the meeting is planned to be held
between October 1-4 on a cruise ship operated by Pullmantur Cruises (based in Spain), fully equipped with
facilities to hold such a scientific meeting. On behalf of the IACS and the Organizing Committee we have
great pleasure in inviting you to this fascinating scientific meeting presented on the following topics:
• Clinical and theoretical aspects of ventricular arrhythmias and sudden cardiac death
• Atrial fibrillation: clinical therapy, novel and future strategies of AF management
• Clinical and theoretical aspects of heart failure
• Cardioprotection, clinical application of cardioprotection
• Genetics and cardiovascular disease
• Coronary angiogenesis from bench to bedside
The translational scientific meeting will feature both basic science and clinical sessions, including lectures of
invited speakers and oral communications selected from submitted abstracts. We would like to provide
opportunities for a number of young investigators to discuss their latest results in both oral and poster
presentations.
We believe that your participation will greatly contribute to the success of the meeting and provide an
opportunity to discuss the latest advances in experimental and clinical cardiovascular research. In addition to
high quality science, the organisers wish to provide a friendly atmosphere aboard ship and in addition, various
relaxing and cultural programmes will be available. We invite you to join us at this meeting, to renew old
friendships, and to make new ones! Updated information and the application form will be available on the
homepage of IACS European Section: http://www.iacs.sav.sk/meetings.html
Chairman of the Meeting: Prof. András Varró, MD, DSc
Honorary Chairman of the Meeting: Prof. Naranjan S. Dhalla, PhD, MD (Hon), DSc (Hon)
Organizing secretariat:
Dr. István Baczkó, Dr. Norbert Jost, Dr. László Virág
Department of Pharmacology & Pharmacotherapy
University of Szeged
Dóm tér 12, H-6720 Szeged, Hungary
Tel.: +36-62-545-682, Fax: +36 -62-545-680
E-mail: [email protected] or
[email protected]
[email protected]
Scientific Advisory Board
Giuseppe Ambrosio, Perugia, Italy
Monika Bartekova, Bratislava, Slovak Republic
Jerzy Beltowski, Lublin, Poland
Dragan M. Djuric, Belgrade, Serbia
Ferenc Gallyas, Pécs, Hungary
Vladimir Jakovljevic, Kragujevac, Serbia
Keld Kjeldsen, Copenhagen, Denmark
Frantisek Kolar, Prague, Czech Republic
Danina Muntean, Timisoara, Romania
Bohuslav Ostadal, Prague, Czech Republic
Petr Ostadal, Prague, Czech Republic
Zoltán Papp, Debrecen, Hungary
Grant N. Pierce, Winnipeg, Canada
Tania Ravingerova, Bratislava, Slovak Republic
Rolf-Edgar Silber, Halle, Germany
Jaipaul Singh Preston, UK
Jan Slezak, Bratislava, Slovak Republic
Belma Turan, Ankara, Turkey
Guy Vassort, Montpellier, France
Ágnes Végh, Szeged, Hungary
Karl Werdan, Halle, Germany
1
Registration and ship information
Ship name: Zenith. Departure port: Marseille, MPCC Terminal, France. Arrival port: Marseille, MPCC
Terminal, France. Route: Marseille – Livorno (Pisa, Florence) – Bastia, Corsica – Marseille. More information
is available at the website of Pullmantur Cruises: https://www.pullmantur.es/en/portada.html
Registration fee is 600 €/person with double cabin occupancy. Junior registration fee: 400€/person, only
with double cabin occupancy. To qualify for Junior registration fee, the registrant must be a PhD student OR
have a PhD degree obtained in 2013 or later (documentation required) AND must not be older than 38. In case
of single cabin occupancy, with the possibility of one accompanying person, the registration fee is 1200
€/person (with no additional cost but full board hospitality for the accompanying person). The registration fee
also covers on board costs of accommodation (3 nights) and full meals with drink package.
Registration fees should be paid by bank transfer to the following bank account:
________________________________________________________________________________________
Account holder name: IACS-ES FOUNDATION FOR THE FUTURE OF CARDIOLOGY RESEARCH
Bank name: ERSTE BANK HUNGARY ZRT.
SWIFT Code: GIBAHUHB
IBAN Account Number: HU35116000060000000076825530
________________________________________________________________________________________
Please indicate your name and city of origin on the payment. Payment details are also available at the IACSES website: http://www.iacs.sav.sk/meetings.html
All participants will receive an official Certificate of Attendance and an official Conference Registration
Fee Invoice.
Since the number of available cabins is limited, please make sure you register at your earliest convenience,
registrations will be handled at a first-come first-served basis.
At this late stage we can accept abstracts only for poster presentations. Abstract submission forms can be
downloaded from the IACS-ES website: http://www.iacs.sav.sk/meetings.html
Publication opportunity for presenters
The abstracts of all oral and poster presentations (except late registration abstracts) will be published in
Current Research: Cardiology. Presenters will be encouraged to submit a full manuscript based on the
material presented at the conference for consideration to be published in the Canadian Journal of Physiology
and Pharmacology or Current Research: Cardiology. Manuscript submissions will be subjected to peerreview process.
Poster presentations:
Please prepare your poster in the “Portrait” layout (orientation). Poster dimensions should be the following:
Width: 86-90 cm; Height: 120-140 cm.
Poster boards (width: 100 cm), adhesive tapes and plasticine will be provided to presenters.
There will be two poster sessions: Poster Session I – October 1, 17:00-19:00 for posters with even number,
and Poster Session II – October 2, 17:00-19:00 for posters with odd numbers. Poster numbers will follow the
poster abstract numbers published in the supplement of Current Research: Cardiology (Vol. 3. No. 3. Autumn,
included in the conference materials package on site).
____________________________________________________________________________________________________________
Ship Embarkation: 11:00-12:30, October 1, 2016.
PIER 183, TERMINAL B, môle léon Gourret, port of Marseille, Marseille, France.
The Marseille Provence Cruise Center is accessed via gate 4 of the Grand Port Maritime de Marseille.
Port of Marseille - Gate 4, Chemin du Littoral, 13015 Marseille.
Ship Arrival: October 4, 2016. Please note that m/v Zenith will be docked at Terminal B, Pier 181.
____________________________________________________________________________________________________________
2
Conference Program
Ship embarkation: Marseille, France, 11:00-12:30, October 1, 2016.
Day 1 (October 1, 2016) – Ship leaves Marseille, France
11:00-12:30
12:30-13:30
Ship embarkation (separate check-in desks for conference attendees provided)
Lunch
Lecture Hall A (Theatre): PLENARY LECTURES
Chairs: András Varró/Bohuslav Ošt’ádal
14:00-14:10
Opening ceremony
14:10-14:50
Naranjan Dhalla Honorary Lecture
Ursula Ravens, Freiburg, Germany
Antiarrhythmic drugs in atrial fibrillation – do we know what to target?
14:50-15:30
20th Anniversary of IACS – Ceremonial Plenary Lecture
Naranjan Dhalla, Winnipeg, Canada
Antiplatelet agents as a novel therapy of heart failure due to myocardial infarction
16:00-17:00
Safety regulations presentation and drill by Pullmantur staff
Lecture Halls C and E (Library Room and Conference Room)
17:00-19:00
Karl Werdan Poster Session (even poster numbers, with wine and cheese)
Jury: Deepak Srivastava, Belma Turan, Judit Barta, Monika Bartekova, Thomas Jespersen, András Farkas
21:00-23:00
Dinner
Day 2 (October 2, 2016) – Ship arrives in Livorno, Italy (~ 7:00 AM)
Facultative program for accompanying persons:Excursion to Pisa and Florence
Parallel sessions in Lecture Halls B (Disco Bar), C (Library), D (Cardroom) and E (Conference Room)
9:00-10:30
Parallel oral sessions (invited speakers and oral abstract presentations)
Lecture Hall B – Clinical (Disco Bar)
Lecture Hall C – Basic science (Library)
Chairs: Karl Werdan/Vladimir Jakovljevic
Chairs: Ferenc Gallyas/Danina Muntean
Frans HH Leenen, Ottawa, Canada (O 20)
Role of CNS MR - AT1R signaling in heart failure
Ferenc Gallyas, Pécs, Hungary (O 10)
Role of mitochondrial integrity and network dynamics in
regulation of cell death
Karl Werdan, Halle, Germany (O 37)
Septic cardiomyopathy
Bohuslav Ošt’ádal, Prague, Czech Republic (O 25)
Protection of the developing heart- possible role of
mitochondria
Vladimir Jakovljevic, Kragujevac, Serbia (O 14)
Oxidative stress in exercise: possible interventions with
antioxidants for better adaptation
Danina Muntean, Timisoara, Romania (O 22)
Improvement of mitochondrial function by methylene blue
in experimental diabetes: a promising case of drug
repurposing
3
Lecture Hall D – Basic science (Cardroom)
Lecture Hall E – Basic science (Conference Room)
Chairs: Antonio Zaza/Dobromir Dobrev
Chairs: Tania Ravingerova/Ricardo Gelpi
Dobromir Dobrev, Essen, Germany
New insights into the molecular
paroxysmal atrial fibrillation
mechanisms
of
Antonio Zaza, Milan, Italy (O 39)
Modulation of the intracellular calcium store as an
antiarrhythmic endpoint
Thomas Jespersen, Copenhagen, Denmark (O 15)
Combined effect of class III antiarrhythmic agents and
Ca2+-activated K+ (SK) channel inhibition in an isolated
heart model of atrial fibrillation
Tamás Csont, Szeged, Hungary
Hypercholesterolemia-induced oxidative/nitrative stress
and cardiac dysfunction: the role of NADPH oxidases and
microRNA-25
10:30-11:00
Tania Ravingerova, Bratislava, Slovakia (O 29)
Activation of peroxisome proliferator-activated receptors
as a potential mechanism of remote preconditioninginduced cardioprotection in healthy and diseased hearts
Ricardo Gelpi, Buenos Aires, Argentina
Myocardial triggers involved in remote
preconditioning activation
ischemic
Frantisek Kolar, Prague, Czech Republic (O 17)
Cardioprotective effect of chronic hypoxia combined with
exercise training
Csaba Csonka, Szeged, Hungary
Decellularized extracellular matrix
ischemia-reperfusion injury
(ECM)
against
Coffee break
Lecture Hall A (Theatre): PLENARY LECTURES
Chairs: Zoltán Csanádi/Dobromir Dobrev/Grant Pierce
11:00-11:40
Kálmán Tóth, Pécs, Hungary
Myocardial and vascular protection by PARP inhibitors
11:40-12:20
David Eisner, Manchester, UK
Systolic and diastolic calcium: in and out of control
12:20-13:00
Gary Lopaschuk, Edmonton, Canada
Targeting cardiac fatty acid oxidation to treat heart failure
13:00-15:00
Lunch
Parallel sessions in Lecture Halls A (Theatre), B (Disco Bar), C (Library), D (Cardroom)
15:00-16:50
Parallel oral sessions (invited speakers and oral abstract presentations)
Lecture Hall A (Theatre) - Young Investigator
Award Competition
Lecture Hall B – Basic science (Disco Bar)
Chairs & Jury: Ursula Ravens/Gary Lopaschuk/Ján
Slezák/Helen Maddock/Zoltán Papp/Rakesh Kukreja
Chairs: Devendra Agrawal/Jerzy Beltowski
Safa Abdul Ghani, Bristol, UK (YIA1)
Remote ischemic preconditioning triggers changes in heart
rate, heart rate variability, microcirculatory blood flow
and cardiac energetics
Nevena Jeremic, Louisville, USA (YIA2)
Ablation of TLR-4 mitigates blood pressure response
during hyperhomocysteinemia
Kornél Kistamás, Manchester, UK (YIA3)
Dependence of diastolic calcium levels on frequency and
extracellular calcium concentration
Zsófia Kohajda, Szeged, Hungary (YIA4)
Cellular electrophysiological and antiarrhytmic effect of
sodium/calcium exchanger (NCX) inhibition
Victoria L Mascetti, Cambridge, UK (YIA5)
Human-mouse chimerism validates human stem cell
pluripotency and cardiovascular differentiation
Marta Rusek, Lublin, Poland (YIA6)
Effect of bisphosphonates on paraoxonase 1 (PON1)
activity and gene expression in various tissues in patients
with coexisting osteoporosis and increased risk of
atherosclerosis
Devendra Agrawal, Omaha, USA (O 1)
Novel mechanisms underlying instability
atherosclerotic arteries
of plaques in
Jerzy Beltowski, Lublin, Poland (O 5)
Effect of statins on vitamin D metabolites: implications for
pharmacotherapy of cardiovascular diseases
Zoltán Papp, Debrecen, Hungary (O 26)
New vasodilators, inotropes and inodilators in the
management of acute heart failure
Paramjit S Tappia, Winnipeg, Canada (O 33)
A novel foot bathing approach for the treatment of foot
ulcers due to periperal arterial disease: a case study
Hideo A Baba, Essen, Germany (O 2)
Bathing in CO2 enriched water alters protein expression in
keratinocytes of skin tissue
4
Krisztina Váczi, Debrecen, Hungary (YIA7)
Sarcolemmal Ca2+-entry through L-type Ca2+ channels
controls the profile of Ca2+-activated Cl− current in canine
ventricular myocytes
Lecture Hall C – Clinical (Library)
Lecture Hall D – Basic science (Cardroom)
Chairs: Chandrasekharan Kartha/Ramesh Goyal
Chairs: Dinender K Singla/M.-Saadeh Suleiman
Zoltán Csanádi, Debrecen, Hungary (O 8)
Mechanisms of atrial fibrillation: lessons from a 20-year
experience of transcatheter ablation
Michael Czubryt, Winnipeg, Canada (O 7)
Development of novel therapeutics for cardiac fibrosis
Chandrasekharan Kartha, Kerala, India (O 16)
Tetralogy of Fallot: molecular defects in the cardiac right
ventricle outflow
Dinender K Singla, Orlando, USA
Stem cells derived exosomes attenuate adverse cardiac
remodeling in doxorubicin induced cardiomyopathy
Gabriella Malfatto, Milano, Italy (O 21)
Correlation of pulmonary pressure and thoracic
impedance assessed by remote monitoring devices
M.-Saadeh Suleiman, Bristol, UK (O 32)
The role of cAMP/PKA/Epac signalling pathway in
cardioprotection
Ramesh G Goyal, Chennai, India (O 12)
Genome based diagnostics and therapeutics in cardiovascular complications: any light in the tunnel?
Anikó Görbe, Budapest, Hungary (O 11)
Cell-based platforms for cardioprotection
Deepak Srivastava, San Francisco, USA (O 31)
Cellular reprogramming approaches for cardiovascular
disease
Monika Bartekova, Bratislava, Slovakia (O 4)
Potential effects of quercetin in cardioprotection
Lecture Halls B and C (Conference Room and Library Room)
17:00-19:00
Keld Kjeldsen Poster Session (odd poster numbers, with wine and cheese)
Jury: Deepak Srivastava, Belma Turan, Judit Barta, Monika Bartekova, Thomas Jespersen, András Farkas
21:00-23:00
Dinner
Day 3 (October 3, 2016) – Ship arrives in Bastia, Corsica (~ 7:00 AM)
Free Time – Optional Social Program: Corsica excursion – approx. 50€/person (by Pullmantur)
13:00-15:00
[14:00-16:00]
Lunch
IACS Board Meeting for Council members (Teens’ Club Room)
Parallel sessions in Lecture Halls A (Theatre), B (Disco Bar), C (Library), D (Cardroom)
15:00-17:00
Parallel oral sessions (invited speakers and oral abstract presentations)
Lecture Hall A – Clinical (Theatre)
Lecture Hall B – Clinical (Disco Bar)
Chairs: Simona Dragan/Buttar S Harpal
Grant Pierce, Winnipeg, Canada (O 27)
Addressing the problem of hypertension
Chairs: Helen Maddock/András Farkas
Helen Maddock, Coventry, UK
New therapeutic strategies to protect the heart from
cancer drugs
Tetsuya Yamada, Nagoya, Japan (O 38)
Clinical experiences of CO2 foot bath therapy: effects on
peripheral arterial disease of dialysis patients with
diabetes
Hiroaki Hasebe, New York, USA (O 13)
Utilization of near infrared spectroscopy imaging of
chronic wound by CO2 enriched water foot bathing
treatment
Simona Dragan, Timisoara, Romania (O 9)
Predictors of progression of coronary heart disease in the
clinical setting: life is not mathematics
Buttar S Harpal, Ottawa, Canada (O 6)
Clinical evidence for the benefits of mediterranean-type
diet and lifestyle modifications in the prevention of
cardiovascular diseases
5
Lidia Hategan, Szeged, Hungary (O 40)
Screening for known and novel genetic variants in ion
channel diseases with next generation sequencing
András Farkas, Szeged, Hungary
Acquired long QT syndrome: does it matter for the
clinician or just for the safety pharmacologist?
István Koncz, Szeged, Hungary (O 18)
Early repolarization syndrome
Lecture Hall C – Basic science (Library)
Lecture Hall D – Basic science (Cardroom)
Chairs: Katja E Odening/Tamás Radovits
Chairs: Rakesh Kukreja/Belma Turan
Katja E Odening, Freiburg, Germany (O 24)
Transgenic rabbit models for inherited arrhythmia
disorders long-QT and short-QT syndrome
Ján Slezák, Bratislava, Slovakia (O 30)
Protection of the heart in situations of increased
production of oxygen free radicals: radiation and
reperfusion injury
Tamás Radovits, Budapest, Hungary (O 28)
(Patho)physiology of athlete's heart
Norbert Nagy, Szeged, Hungary (O 23)
Possible therapeutic implications of the selective cardiac
Na+/Ca2+ exchanger inhibition: what can we learn from
the pharmacological studies?
Attila Farkas, Szeged, Hungary (O 41)
The assessment of structural remodeling and
proarrhythmic sensitivity in a new rabbit athlete's heart
model
László Virág, Szeged, Hungary (O 36)
Cellular electrophysiological investigation of the chronic
and acute effects of desethylamiodarone in dog cardiac
ventricular preparations
17:30-19:00
Award Ceremony (Disco Bar)
21:00-23:00
Dinner
Belma Turan, Ankara, Turkey (O 34)
An investigation on the distribution of zinc-transporters in
failing hearts of mammalians
Dragan Djuric, Belgrade, Serbia
Homocysteine and methionine:
cardiovascular system
risk
tango
for
Suresh Tyagi, Louisville, USA (O 35)
Role of H2S in in cardiovascular remodeling
Rakesh Kukreja, Richmond, USA (O 19)
PDE5 inhibition in protection of diabetic heart
Judit Barta, Debrecen, Hungary (O 3)
Altered myofilament protein phosphorylation pattern
contributes to increased right ventricular passive stiffness
in a rat model of post-ischemic heart failure
Day 4 (October 4, 2016) – Ship arrives in Marseille, France (~ 8:00 AM)
Arrival and disembarkation.
SPONSORS OF THE MEETING
International Academy of
Cardiovascular Sciences
Hungarian Society
of Cardiology
Mitsubishi Rayon Cleansui
Co. Ltd. Japan
MEASURING DEVELOPMENT
ENGINEERING
Pulsus Group,
Canada
6
Mission of the European Section of International Academy of Cardiovascular Sciences
(IACS-ES)
The general mission of IACS is to promote cardiovascular science, scientific education and
interaction of scientists.
In Europe, there are several scientific organizations in the cardiovascular field, such as the national
cardiological societies within the European Society of Cardiology (ESC) with its 12 Working Groups,
and the International Society for Heart Research – European Section (ISHR-ES). However, the
European Section of IACS has a distinctly different mission than those above mentioned
organizations. The goal of IACS-ES is not to compete but rather to cooperate with other scientific
organizations in the field, focused on the aspects that are not completely covered by other societies.
According to this idea – in addition to the general commitment to promote high quality
cardiovascular science in Europe – the IACS-ES has four additional main specific aims.
• Since scientific background, traditions, training and funding vary considerably depending on
different regions in Europe, the European Section of IACS-ES would focus on promoting
cardiovascular science in European countries, where the conditions for scientific excellence
including research, training and funding are less well-established or supported. Such regions of
Europe are: Central and Eastern Europe, the Balkan countries and some countries in Southern
Europe. To achieve this goal, the IACS-ES would like to help organizing meetings in these regions of
Europe encouraging the participation of top scientists from all over the world. Also, the IACS-ES
would like to encourage and acknowledge the contribution of scientists from other parts of Europe
and the world who play a significant role helping to promote cardiovascular sciences in the so far
less successful countries in Europe. The IACS-ES would consider it as a priority to encourage
young scientists, postgraduate or PhD students to participate in the meeting organized by IACS via
offering travel grants and young investigator and poster awards. In addition, the IACS-ES would
like to help organizing scientific summer schools for young scientists and students to get familiar
with modern experimental techniques and build up scientific connections throughout Europe.
• Since some of the cardiovascular meetings do not provide a sufficient basis for interaction
between the basic science and clinical communities, the IACS-ES would focus on encouraging and
promoting direct and strong interactions between basic scientists and clinical cardiologists by
putting together experimental and clinical presentations in joint sessions providing a platform for
common discussions.
• High-tech industry including pharmaceutical industry is not evenly distributed in Europe. It is
relatively well-developed in Western and Northern Europe and it is less-developed in EasternCentral, Southern Europe and in the Balkan region. Therefore, one important goal of IACS-ES is to
provide direct interactions for basic scientists and clinical cardiologists with industrial
representatives from all over European countries. In addition, it is also important to provide a
forum for companies operating in the less-advanced regions of Europe helping interactions with
leading scientists from all over the world with scientists working in those regions. The latter may
help those companies to increase the success of their business and also bring better opportunity
for local cooperation to enhance their innovation strength and providing experts for their potential
needs.
• Since IACS-ES closely interacts with other sections of IACS worldwide, it can help to provide a
wide range of interactions between cardiovascular scientists in Europe and the rest of the world. In
this respect, IACS-ES can facilitate participation of European scientists in meetings outside Europe
on a mutual basis. Also, the official Journal of IACS, the “CV Network”, which contains important
information about the life of the IACS – including a meeting calendar - can be distributed to the
national cardiological societies who would take part in the Academic Membership program of the
IACS-ES. In this way, the “CV Network” can provide useful information for national cardiological
societies in Europe with their several thousand members, and IACS-ES can also inform the
members of IACS worldwide regarding main ongoing activities in Europe including meetings.
www.iacs.sav.sk
Google: IACS-ES
7