Download Module Catalogue for the Master Degree Programme Molecular Life

Module Catalogue
for the Master Degree Programme
Molecular Life Sciences
Status: 2016
Faculty of Biology and Pharmacy
List of abbreviations
cp
L
S
E
P
Ex
SS
WS
hpw
Mc
credit point(s)
Lecture
Seminar
Exercise
Practical course
Excursion
Summer Semester
Winter Semester
hours per week
Module coordinator
Curriculum Master Molecular Life Sciences
1. General overview according to academic years
2nd academic year
1st academic year
WS
SS
WS
MMLS.G1
7 hpw
MMLS.A1
7 hpw
Molecular Developmental Biology Mol. Devel. of Model Systems
MMLS.T1
Specialisation Module MMLS
MMLS.G2
Molecular Genetics
MMLS.T2
Project Module MMLS
7 hpw
MMLS.A2
Evol. Devel. Biology
MMLS.G3
6 hpw
Molecular Cell Biology
7 hpw
SS
MMLS.T3
Master Thesis MMLS
1 hpw
MMLS.A3
7 hpw
Developmental Control Gene
MMLS.A4
Gene Regulation
7 hpw
MMLS.A5
7 hpw
Theoretical Systems Biology
MMLS.A6
7 hpw
Applied Systems Biology
MMLS.A7
Signal transduction
7 hpw
MMLS.A9
7 hpw
Biological Clock and Temporal
Gene Expression
MMLS.A10
7 hpw
Mol. Med. of Ion Transport
MMLS.A17
7 hpw
Genome Integrity, Tumors and
Ageing
MMLS.A12
7 hpw
Organelles: Devel. a. Function
MMLS.A13
Cellular Networks
7 hpw
MMLS.A14
8 hpw
Systematic Neurobiology
MMLS.A15
8 hpw
Development and Plasticity of
Nervousl System II
MMLS.A16
7 hpw
Symbiosis, Signalling and
Metabolism
Basic modules (compulsory)
Advanced modules (compulsory elective)
Interdisciplinary module:
Modules from other degree programmes will be included after mandatory mentors advise if they
particularly enhance the interdisciplinary character of the study course. Examples could be – aside
from other life science subjects (e. g. offered within the Master programme Biochemistry, Molecular
Medicine or Microbiology) – specifically Ethics, Scientific English, Nanotechnologies, Photonics. Also
an internship at external research institutions can be accredited after previous student advisory service
within the scope of an advanced module.
International mobility / Mobility window
Study stays abroad within the Master degree programme Molecular Life Sciences are possible and
desired. For the support of students, who want to go abroad, a special entry on the website publishes
links to the International Office, the Erasmus Programme, the networking amongst Coimbra
Universities, current links (such as RISE) and the offer of an individual mentoring.
To make the recognition of achievements easier, a “Learning Agreement” about the planned study
programme should be arranged with the responsible professor of the degree programme and should
be provided to the Study and Examination Office. Possibilities of a degree programme related mobility
can be given by the responsible professor of the degree programme as well as the Study and
Examination Office.
2. General Overview According to Subject-Related Semesters and Credit Points
Module number
Module name
Credit points
1st Semester
MMLS.G1
MMLS.G2
MMLS.G3
3 Basic modules
Basic module „Molecular Developmental Biology“
Basic module „Molecular Genetics“
Basic module „ Molecular Cell Biology “
10
10
10
2nd Semester
MMLS.A1
3 Advanced modules 1
Advanced module „Molecular Developmental Biology
of Model Systems “
Advanced module „Evolutionary Developmental
Biology“
Advanced module „Developmental Control Genes“
Advanced module „Gene Regulation“
Advanced module „Theoretical Systems Biology“
Advanced module „Applied Systems Biology“
Advanced module „Signal Transduction“
Advanced module „Biological Clock and Temporal
Gene Expression“
Advanced module „Molecular Medicine of Ion
Transport“
Advanced module „Genome Integrity, Tumors and
Ageing”
Advanced module „Organelles: Development and
Function“
Advanced module “Cellular Networks”
Advanced module “Systematic Neurobiology”
Advanced module “Development and Plasticity of
Nervous System II”
Advanced Module “Symbiosis, Signalling and
Metabolism”
MMLS.A2
MMLS.A3
MMLS.A4
MMLS.A5
MMLS.A6
MMLS.A7
MMLS.A9
MMLS.A10
MMLS.A17
MMLS.A12
MMLS.A13
MMLS.A14
MMLS.A15
MMLS.A16
10
10
10
10
10
10
10
10
10
10
10
10
10
10
10
3rd Semester
MMLS.T1
MMLS.T2
2 Modules
Specialisation Module
Project Module
10
20
4th Semester
MMLS.T3
Master thesis
Master thesis
30
_______________________________________
1 The
Advanced modules can be freely chosen.
Record sheet Master Molecular Life Sciences
Module
Work performed
Basic module 1
Lectures
Seminar
Basic module 2
Lectures
Seminar
Basic module 3
Lectures
Seminar
Advanced module 1
(can be freely chosen from the range
of the courses offered in Molecular Life
Sciences)
Advanced module 2
(can be freely chosen from the range
of the courses offered in Molecular Life
Sciences)
Advanced module 3
(can be freely chosen from the range
of the courses offered in Molecular Life
Sciences)
Specialisation module
Project module
Master thesis
Grade
Signature
Module Overview for the Master’s Programme Molecular Life Sciences (MMLS)
G
A
T
Basic module (compulsory module)
Advanced module (compulsory elective module)
Thesis (Master thesis)
1st Semester:
MMLS.G1: Molecular Developmental Biology
L Molecular Developmental Biology I
(Mc: Theißen)
Theißen, Damen
WS/SS
WS
hpw
2
L
Molecular Developmental Biology II
Olsson, Englert, Baniahmad
WS
2
L
Gene Regulatory Networks
Theißen, Damen
WS
1
S
Comparative and Evolutionary
Developmental Biology
Damen, Olsson, Theißen
WS
2
MMLS.G2: Molecular Genetics
L Molecular Genetics I
(Mc: Baniahmad)
Baniahmad, Heinzel, Theißen
7
10
WS/SS
WS
hpw
2
cp
L
Molecular Genetics II
Baniahmad, Saluz, Damen
WS
2
L
Systems Biology
Schuster, Platzer, Dittrich
WS
1
S
Molecular Genetics
Baniahmad
WS
2
MMLS.G3: Molecular Cell Biology
L Molecular Cell Biology I
(Mc: Sasso)
Jungnickel, Hemmerich
L
Molecular Cell Biology II
Oelmüller, Sasso
L
Molecular Cell Biology III
Mittag
S
Molecular Cell Biology
Hemmerich, Oelmüller, Sasso,
Mittag
cp
7
10
WS/SS
WS
hpw
2
cp
WS
2
WS
2
WS/SS
1
7
10
WS/SS
SS
hpw
2
cp
SS
5
2nd Semester: 3 advanced modules can be freely chosen
MMLS.A1: Molecular Developmental Biology of Model Systems (Mc: Englert)
S Molecular Developmental Biology of Model Englert, Theißen, Damen
Systems
P Molecular Developmental Biology of Model Englert, Theißen, Damen
Systems
MMLS.A2: Evolutionary Developmental Biology (Mc: Theißen)
S Evolutionary Developmental Biology
Theißen, Damen
P
Evolutionary Developmental Biology
Theißen, Damen
7
10
WS/SS
SS
hpw
2
cp
SS
5
7
10
MMLS.A3: Developmental Control Genes
S Developmental Control Genes
P
Developmental Control Genes
MMLS.A4: Gene Regulation
S Gene Regulation
P
(Mc: Theißen)
Theißen, Damen
Theißen, Damen
(Mc: Baniahmad)
Baniahmad
Gene Regulation
Baniahmad, Heinzel, Englert, NN
MMLS.A5: Theoretical Systems Biology
L Analysis of Gene Expression
(Mc: Schuster)
Guthke
WS/SS
SS
hpw
2
SS
5
7
10
WS/SS
SS
hpw
2
cp
SS
5
7
10
WS/SS
SS
hpw
2
cp
L
Metabolic and Regulatory Networks
Schuster
SS
2
E
Metabolic and Regulatory Networks
Schuster
SS
1
P
Metabolic and Regulatory Networks
Schuster
SS
2
MMLS.A6: Applied Systems Biology
P Applied Systems Biology
S
Applied Systems Biology
MMLS.A7: Signal Transduction
S Signal Transduction
P
Signal Transduction
(Mc: Mittag)
Mittag, Saluz
Mittag
(Mc: Liebmann)
Spänkuch, Heinzel, Wetzker
Spänkuch, Heinzel, Wetzker
MMLS.A9: Biological Clock and Temporal Gene Expression
S
P
(Mc: Mittag)
Current Topics on Molecular Mechanisms of Mittag
Circadian Clocks and Temporal Gene
Expression
Molecular Chronobiology - Temporal Gene Mittag and members of staff
Expression
MMLS.A10: Molecular Medicine of Ion Transport (Mc: Heinemann)
L Ion Transport and Disease
Heinemann, Schönherr
S Current Topics on the Structure and
Heinemann
Function of Ion Channels and Transporters
P Membrane Processes and Transport
Heinemann and members of staff
cp
7
10
WS/SS
SS
hpw
5
cp
SS
2
7
10
WS/SS
SS
hpw
2
cp
SS
5
7
10
WS/SS
hpw
cp
SS
2
SS
5
7
10
WS/SS
SS
SS
hpw
2
1
cp
3
2
SS
4
7
5
10
MMLS.A17: Genome Integrity, Tumors and Ageing (Mc: Jungnickel)
V Genomic Instability and Tumor Biology
Jungnickel, Grosse
WS/SS
SS
hpw
2
S
Genetic and Cellular Plasticity
Jungnickel
SS
2
P
Genetic and Cellular Plasticity
Jungnickel
SS
4
MMLS.A12: Organelles: Development and Function (Mc: Oelmüller)
S Organelles: Development and Function
Oelmüller
P
Organelles: Development and Function
MMLS.A13: Cellular Networks
S Cellular Networks
P
Oelmüller
(Mc: Jungnickel)
Jungnickel
Cellular Networks
MMLS.A14: Systems Neurobiology
L Systems Neurobiology
Jungnickel
(Mc: Bolz)
8
10
WS/SS
SS
hpw
2
cp
SS
5
7
10
WS/SS
SS
hpw
2
cp
SS
5
7
10
cp
Bolz
WS/SS
SS
hpw
2
S
Systems Neurobiology
Bolz
SS
2
P
Systems Neurobiology
Bolz
SS
4
MMLS.A15: Development and Plasticity of Nervous System II (Mc: Bolz)
L Development and Plasticity of Nervous
Bolz, Lehmann
System II
8
10
WS/SS
SS
hpw
2
cp
S
Development and Plasticity of Nervous
System II
Bolz, Lehmann
SS
2
P
Development and Plasticity of Nervous
System II
Bolz, Lehmann
SS
4
MMLS.A16: Symbiosis, Signaling and Metabolism
(Mc: Sasso)
cp
8
10
WS/SS
hpw
cp
L
Symbiosis, Signaling and Metabolism
Sasso, Mahlow
SS
1
S
Symbiosis, Signaling and Metabolism
Sasso
SS
1
P
Symbiosis, Signaling and Metabolism
Sasso
SS
5
7
10
3rd Semester:
MMLS.T1: Specialisation Module MMLS (Mc: All persons responsible for Basic and
Advanced modules of the Master programme MLS)
P Current Methods MMLS
according to agreement
WS/SS
hpw
cp
WS
10
MMLS.T2: Project module MMLS (Mc: All persons responsible for Basic and
Advanced modules of the Master programme MLS)
P Project laboratory course MMLS
according to agreement
WS/SS
hpw
cp
WS
20
4th Semester:
MMLS.T3: Master thesis MMLS (Mc: All persons responsible for Basic and
Advanced modules of the Master programme MLS)
P Master thesis MMLS
according to agreement
WS/SS
hpw
cp
SS
30
Module descriptions
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.G1
Molecular Developmental Biology
Theißen
none
Requirement for further modules
Compulsory module, Basic module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, WS
1 semester
L: 5 hpw
S: 2 hpw
-105 h
-195 h
Based on the module BB 3. MLS 1 (Developmental
Genetics) of the Bachelor degree programme the module
provides in-depth basics in Developmental Biology on the
broad base, particularly in Molecular Biology, Genetics,
Evolutionary Biology, Molecular Medicine. The focus is on
lectures of text book knowledge about the development of
model organisms, whereby animals (e.g. Drosophila) and
plants (e.g. Arabidopsis) are handled comparatively.
Particular attention is paid to the methods of the Molecular
Developmental Genetics and the role of Gene Regulatory
Networks in the development.
Learning and qualification objectives Deepening of basics in Developmental Biology; basic
knowledge for essential research directions in Molecular
Life Sciences; deepened overview of the subject area as
whole; Presentation of the scientific results giving a
lecture; dealing with English scientific literature. Regular
participation in the seminar is required to reach the study
objectives of the module. The teaching staff will inform
about further details at the beginning of the courses.
Admission requirements for the
module examination
Requirements for the award of
Written examination on the contents of all lectures (70 %),
credit points (forms of examination,
Seminar presentation (30 %)
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.G2
Molecular Genetics
Baniahmad
None
Requirement for further modules
Compulsory module, Basic module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, WS
1 semester
L: 5 hpw
S: 2 hpw
-105 h
-195 h
The focus of the lectures is on the structure of genomes of
different organisms, chromatin structure and modification,
epigenetics, tumor genetics, structure of genome,
transposons, immuno genetics, comparative genetics and
analysis of genome. Furthermore basics in systems
biology are provided. Current literature on the scientific
field and the newest techniques are discussed in the
seminar.
Learning and qualification objectives Acquirement of a wide perspective at the meaning of
molecular genetics for the organisms, mechanisms of the
gene regulation, genomics; introduction to systems
biology; learning about the newest molecular genetic
techniques in theory as well as importance of the
epigenetics and chromatin; acquisition of a scientific style
in giving a speech and presentations. Regular participation
in the seminar is required to reach the study objectives of
the module. The teaching staff will inform about further
details at the beginning of the courses.
Admission requirements for the
module examination
Requirements for the award of
Written examination on the contents of all lectures (70 %),
credit points (forms of examination,
Seminar presentation (30 %)
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.G3
Molecular Cell Biology
Sasso
None
Requirement for further modules
Compulsory module, Basic module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, WS/SS
2 semesters
L: 6 hpw
S: 1 hpw
-105 h
-195 h
This module will extend the basic knowledge of molecular
cell biology, particularly molecular biology, genetics,
systems biology, evolution and develop-ment, and
molecular medicine from module BB3.MLS9, with a wider
scope. The emphasis will be on (a) principles of cell
communication and signalling, structure, function and
transport processes of selected membranes, organisation
of the cell nucleus and the stem cell complex, (b)
molecular processes in plants including genetic methods
for their modification, genome sequencing and function of
small RNAs, and (c) the molecular organisation of
biological clocks, particularly the circadian clock of
selected organisms of prokaryotes, fungi, plants and
animals and the evolution of clock components.
Learning and qualification objectives Extension of basic knowledge of molecular cell biology;
acquisition of knowledge for important fields in molecular
life sciences. Methods for the visualisation of molecules,
organelles and cells, and for the manipulation of proteins,
DNA and RNA in cells; presentation of scientific
knowledge in the form of a talk; reading and discussion of
scientific literature (in English) on aspects of the lecture.
Regular participation in the seminar is required to reach
the study objectives of the module. The teaching staff will
inform about further details at the beginning of the
courses.
Admission requirements for the
module examination
Requirements for the award of
Written examination on the contents of all lectures (70 %),
credit points (forms of examination,
Seminar presentation (30%)
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A1
Molecular Developmental Biology of Model Systems
Englert
at least 1 successfully completed Basic module
Specialisation module , Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
P: 5 hpw
S: 2 hpw
-105 h
-195 h
The module provides knowledge in housing and breeding
of different model organisms (e.g. Arabidopsis, Zebrafish,
mouse); distinction of different developmental stages and
preparation of particular organs; genotyping; expression
analysis (RT-PCR and in situ hybridization);
immunohistochemical processes; fluorescence
microscopy as well as analysis of transgenic plants and
animals.
Learning and qualification objectives Deepening of knowledge in developmental genetics;
acquisition and application of methods of developmental
genetics and/ or developmental biology; gaining of
experience in handling as well as in housing and breeding
of experimental animals and plants; writing of a scientific
protocol, presentation of data and communication in
English. Regular participation in the practical course and
the seminar is required to reach the study objectives of the
module. The teaching staff will inform about further details
at the beginning of the courses.
Admission requirements for the
Writing of a practical course protocol
module examination
Requirements for the award of
Oral examination (70%), Seminar presentation (30%),
credit points (forms of examination,
major course assessment for the practical course
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A2
Evolutionary Developmental Biology
Theißen
at least 1 successfully completed Basic module
Specialisation module , Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
P: 5 hpw
S: 2 hpw
-105 h
-195 h
The focus of this module is on keeping and culturing of
evolutionary biological informative organisms (e.g.
shepherd's purse, orchids, frogs, and fishes). Similarities
and differences of the classical model organisms (e.g.
Arabidopsis, Drosophila, mouse), particularly comparative
morphogenetic studies and sequential and gene
expression analysis are analysed.
Learning and qualification objectives Acquirement of experimental skills in developmental
biology in an evolutionary biological context; providing of
subject-specific terminology, approaches and methods of
the evolutionary developmental biology; writing of a
scientific protocol; presentation of scientific results and
dealing with English scientific literature. Regular
participation in the practical course and the seminar is
required to reach the study objectives of the module. The
teaching staff will inform about further details at the
beginning of the courses.
Admission requirements for the
Writing of a practical course protocol.
module examination
Requirements for the award of
Oral examination (70%), Seminar presentation (30%),
credit points (forms of examination,
major course assessment for the practical course
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A3
Developmental Control Genes
Theißen
at least 1 successfully completed Basic module
Specialisation module , Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
P: 5 hpw
S: 2 hpw
-105 h
-195 h
Analysis of genes, regulating the developmental
processes of animals or plants (e.g. homeobox genes,
MADS box genes) using methods of molecular biology
(e.g. cloning, sequencing, expression analysis, mutant
analysis) and molecular evolution (e.g. multiple sequence
alignments, phylogenetic trees, test on selection).
Learning and qualification objectives Acquirement of experimental skills in Developmental
Genetics and Molecular Biology; deepening of
understanding the complex interdependence between
genotype and phenotype; writing of a scientific protocol;
presentation of scientific results and dealing with English
scientific literature. Regular participation in the practical
course and the seminar is required to reach the study
objectives of the module. The teaching staff will inform
about further details at the beginning of the courses.
Admission requirements for the
Writing of a practical course protocol
module examination
Requirements for the award of
Oral examination (70%), Seminar presentation (30%),
credit points (forms of examination,
major course assessment for the practical course
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A4
Gene Regulation
Baniahmad
at least 1 successfully completed Basic module
Specialisation module, Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly , SS
1 semester
P: 5 hpw
S: 2 hpw
-105 h
-195 h
The content of the module comprises mechanisms of gene
regulation, temporally, spatial and hormonal controlled
gene regulation of gene expression, expression analysis,
newest molecular genetic techniques, biological clocks,
analysis of chromatin and cellular senescence.
Learning and qualification objectives Practical experience in analysing mechanisms of gene
regulation in different biological systems and on different
levels, learning to write a scientific protocol, improving
skills in giving a talk and presentations, data presentation
and communication in English. Regular participation in the
practical course and the seminar is required to reach the
study objectives of the module. The teaching staff will
inform about further details at the beginning of the
courses.
Admission requirements for the
Writing of a practical course protocol.
module examination
Requirements for the award of
Oral examination (70%), Seminar presentation (30%),
credit points (forms of examination,
major course assessment for the practical course
weighting of grades in %)
Module number
Module name
Module coordinator
MMLS.A5
Theoretical Systems Biology
Schuster
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
at least 1 successfully completed Basic module
Specialisation module , Project module, Master thesis
Compulsory elective module, Advanced module
Yearly, SS
1 semester
L: 4 hpw
P: 2 hpw
E: 1 hpw
10 cp
-105 h
-195 h
The lecture Analysis of Gene Expression provides an
overview of chip technologies and their applications; preprocessing of data (models of measurement errors and
normalisation); differential gene expression; supervised learning;
unsupervised learning (cluster analysis); reverse Engineering
(reconstruction of gene regulatory nets); data bases for gene
expression analysis, as well as ethic and legal questions. In the
lecture Metabolic and regulatory networks the following topics
are covered: Enzyme kinetics, balance equations, network
analysis (incl. conservation relations and elementary modes),
dynamic modelling of metabolic and regulatory networks,
metabolic control analysis, modelling of enzyme cascades, ultrasensitivity, bistability, basics in modelling of signal transduction
and calcium oscillation. The content of Exercises/ Practical
course is the analytical/ numeral solution of problems on the
scientific area of the lecture (during the practical course by using
provided programmes).
Learning and qualification objectives Practical understanding of the analysis of Microarray data and
the interpretation of analysis results; insight into methods of
knowledge extraction from the measurement data of molecular
biological high-throughput techniques, acquirement of
theoretical knowledge about the mathematical modelling of
metabolic and (intracellular) regulatory networks, learning about
possibilities of applying linear algebra, convex analysis and
differential equation for this modelling; skills to solve exercises
on modelling under guidance: application of relevant
programmes on simulation of metabolic and regulatory
networks. Regular participation in the practical course and the
exercise is required to reach the study objectives of the module.
The teaching staff will inform about further details at the
beginning of the courses.
Admission requirements for the
Writing protocols for the practical course.
module examination
Requirements for the award of
credit points (forms of examination,
weighting of grades in %)
Oral examination in "Analysis of Gene Expr." (30 %), oral or
written examination in „Metabol. and regul. Netw.“ (70 %), major
course assessment for the practical course.
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A6
Applied Systems Biology
Mittag
at least 1 successfully completed Basic module
Specialisation module , Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
P: 5 hpw
S: 2 hpw
-105 h
-195 h
The module provides knowledge in the following areas:
automated sequencing of DNA , sequence analysis in
silico, DNA and RNA fingerprinting, rapid PCR, enrichment
of cellular sub-proteomes, preparation of samples for
mass spectrometry, mass spectrometry measurements
(LC-ESI-MS) and their bioinformatical analysis: „-omics“
methods.
Learning and qualification objectives Theoretical and practical understanding concerning DNA
sequence analysis, fingerprinting und rapid PCR;
relevance and possibilities of functional genome,
proteome and metabolome analysis; independent
conduction of simple experiments on topics above
including writing of scientific protocols; insight into the
newest literature, data presentation and communication in
English. Regular participation in the practical course and
the seminar is required to reach the study objectives of the
module. The teaching staff will inform about further details
at the beginning of the courses.
Admission requirements for the
Writing of a practical course protocol.
module examination
Requirements for the award of
Oral examination (70%), Seminar presentation (30%),
credit points (forms of examination,
major course assessment for the practical course
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A7
Signal Transduction
Spänkuch
at least 1 successfully completed Basic module
Specialisation module , Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
P: 5 hpw
S: 2 hpw
-105 h
-195 h
The selected current problems and research trends in
signal transduction of G protein-coupled receptors,
cytokine receptors and receptor tyrosine kinases are
discussed in the seminar on the basis of original
publications and reviews; also the relevance of new
scientific findings for molecular medicine and signal
transduction therapy is discussed.
In the practical course you work at a relevant small project
in the context of current projects of the involved research
group.
Learning and qualification objectives Deepening of basic knowledge in the areas: receptors and
signal transduction; independent analysis of original
literature; seminar presentation on a chosen publication
and development of a project proposal on the continuation
of the represented scientific problem. Regular participation
in the practical course and the seminar is required to
reach the study objectives of the module. The teaching
staff will inform about further details at the beginning of the
courses.
Admission requirements for the
Writing of a practical course protocol.
module examination
Requirements for the award of
Oral examination (70%), Seminar presentation (30%),
credit points (forms of examination,
major course assessment for the practical course
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A9
Biological Clock and Temporal Gene Expression
Mittag
at least 1 successfully completed Basic module
Specialisation module , Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
P: 5 hpw
S: 2 hpw
-105 h
-195 h
The main focuses of the module are cultivation and
harvesting of organisms (wild type and clock mutants)
under circadian conditions; measurement of circadian
rhythms with the help of reporter genes or automated
equipment, characterization of clock genes and/ or clock
proteins at transcriptional, translational and posttranslational level.
Learning and qualification objectives Advanced knowledge about physiological and molecular
structure of circadian clocks, evolution of clock
components, chronobiological relevant diseases;
independent conduction of simple experiments on topics
above including writing of scientific protocols; insight into
the newest literature, data presentation and
communication in English. Regular participation in the
practical course and the seminar is required to reach the
study objectives of the module. The teaching staff will
inform about further details at the beginning of the
courses.
Admission requirements for the
Writing of a practical course protocol.
module examination
Requirements for the award of
Oral examination (70%), Seminar presentation (30%),
credit points (forms of examination,
major course assessment for the practical course
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A10
Molecular Medicine of Ion Transport
Heinemann
at least 1 successfully completed Basic module
Specialisation module , Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 Semester
L: 2 hpw
P: 4 hpw
S: 1 hpw
-105 h
-195 h
Introduction to symptoms, diagnosis and therapeutic
approaches for diseases that are related to disorders of
ion transport. In particular the basics in Molecular
Medicine and Physiology are provided for comprehension
of channels-associated diseases.
During the practical course membrane transport and the
function of membrane proteins are analysed with the help
of modern methods.
In the seminar current biomedical publications on the topic
are discussed.
Learning and qualification objectives Lecture: structure and function of relevant transport
molecules and their impact on the cellular function. Learn
about pathophysiological interrelations: diagnosis and
therapy of diseases, which are caused by defects in ion
transport.
Practical course: measurement, quantitative analysis and
graphical/ written presentation of transport processes.
Seminar: oral presentation of current publications. Regular
participation in the practical course and the seminar is
required to reach the study objectives of the module. The
teaching staff will inform about further details at the
beginning of the courses.
Admission requirements for the
Writing of a practical course protocol.
module examination
Requirements for the award of
Oral examination concerning contents of the lecture,
credit points (forms of examination,
seminar and practical course (100%)
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A17
Genome Integrity, Tumors and Ageing
Jungnickel
at least 1 successfully completed Basic module
Specialisation module , Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
V: 2 hpw
P: 5 hpw
S: 2 hpw
-105 h
-195 h
Object of the lecture are the molecular and cell biological
basics of genome integrity, tumor biology, stem cell
biology and of ageing of cells and tissue as well as the
genetic and epigenetic basics of cellular plasticity in the
immune system and the nervous system. Regular and
pathological molecular mechanisms are discussed with
selected literature and a scientific topic has to be prepared
independently (with instructions).
Each student has to attend two seminars of own choice in
the field of stem cell biology, ageing, plasticity in the
immune system or neuronal plasticity and has to take part
actively with a presentation and discussion.
Learning and qualification objectives It is the objective of the module to get an overview on
specific cellular mechanisms which allow plasticity,
degeneration and regeneration of cells and organs as well
as developing an understanding of possibilities of
disorders and effects on the entire organism. Development
of validated, proofed results and classification into a
general scientific context. Regular participation in the
practical course and the seminar is required to reach the
study objectives of the module. The teaching staff will
inform about further details at the beginning of the
courses.
Admission requirements for the
module examination
Requirements for the award of
Two seminar presentations (50% each), major course
credit points (forms of examination,
assessment for the lecture and practical course
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A12
Organelles: Development and Function
Oelmüller
at least 1 successfully completed Basic module
Specialisation module, Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
P: 5 hpw
S: 2 hpw
-105 h
-195 h
Basic molecular methods on the development of
organelles, the communication among organelles, the
gene expression in organelles and the photosynthesis are
provided in the practical course and seminar.
Learning and qualification objectives Understanding of the role of organelles of plant cells and
their importance for the metabolism; practical experience
in molecular and physiological laboratory techniques for
analysis of this context; strategical understanding to be
able to solve scientific problems. Regular participation in
the practical course and the seminar is required to reach
the study objectives of the module. The teaching staff will
inform about further details at the beginning of the
courses.
Admission requirements for the
Writing of a practical course protocol.
module examination
Requirements for the award of
Oral examination (70%), Seminar presentation (30%),
credit points (forms of examination,
major course assessment for the practical course
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS. A 13
Cellular Networks
Jungnickel
at least 1 successfully completed Basic module
Specialisation module, Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
P: 5 hpw
S: 2 hpw
-105 h
-195 h
Topics are molecular basics in formation, maintenance,
modulation and interaction of cellular networks in complex
tissues such as e. g. immune system, nervous system,
tumor tissue or the stem cell niche. Normal and
pathological molecular mechanisms will be discussed with
the help of selected literature and a scientific topic will be
worked out independently (with instruction).
Learning and qualification objectives The aim of the module is to provide an overview of specific
cellular mechanisms, which enable the formation and
function of complex organ systems as well as to develop a
comprehension of possible disorders and their impact on
the entire organism. In the practical course validated and
verified results should be achieved and classified into a
general scientific context. Regular participation in the
practical course and the seminar is required to reach the
study objectives of the module. The teaching staff will
inform about further details at the beginning of the
courses.
Admission requirements for the
Writing of a practical course protocol.
module examination
Requirements for the award of
Two seminar presentations (50% each), major course
credit points (forms of examination,
assessment for the practical course
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS. A 14
Systems Neurobiology
Bolz
at least 1 successfully completed Basic module
Specialisation module, Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
L: 2 hpw
P: 4 hpw
S: 2 hpw
-120 h
-180 h
What and how we sense, think and feel is also affected by
the architecture of our brain. The brain again is solely the
product of evolution and therewith formed by incidental
mutations and selection. Thus it is no design of engineers
or computer scientists. This has important consequences
on how we realise the world and how we experience
ourselves in this world. The lecture teaches insight to the
functional architecture of the brain and is dealing with
neuronal mechanisms of cognition, learning and memory
processes as well as neuronal biological basics of
emotions and awareness.
In the seminar current papers on selected topics of the
lecture will be presented and discussed by the students.
In the practical course, among other things, the students
will perform behavioral tests with mice and optical imaging
of neuronal activity in the visual cortex.
Learning and qualification objectives The aim of this module is to get insight into the functional
architecture of the brain and the neuronal mechanisms.
Realisation of experiments on above mentioned topics,
including writing of scientific protocols, presentation of
scientific results and dealing with scientific literature.
Regular participation in the practical course and the
seminar is required to reach the study objectives of the
module. The teaching staff will inform about further details
at the beginning of the courses.
Admission requirements for the
Writing of a practical course protocol.
module examination
Requirements for the award of
Written examination concerning contents of the lecture
credit points (forms of examination,
(70%), seminar presentation (30%), major course
weighting of grades in %)
assessment for the practical course
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS. A 15
Development and Plasticity of the Nervous System
Bolz
at least 1 successfully completed Basic module
Specialisation module, Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
L: 2 hpw
P: 4 hpw
S: 2 hpw
-120 h
-180 h
This module provides an overwiew about fundamental
processes in development and plasticity of the nervous
system. Major points are embryonic development of the
nervous system (neuronal migration, formation of specific
neuronal connections), postnatal developmental plasticity
(experience and activity dependent modifications of
neuronal circuits, critical periods) and plasticity in the adult
brain (learning induced plasticity, restoration of function in
the aging brain). In the practical course different in vitro
assays are performed to examine neuronal migration and
axon guidance. Furthermore, the analysis of transgenic
mice with modified neuronal circuits will also be part of the
practical course.
Learning and qualification objectives Overview on molecular and cellular processes of
development and plasticity of the nervous system; critical
discussion of current publications on this topic;
independent use of methodical approach of developmental
neurobiology; guided analysis of the collected data with
relevant methods. Regular participation in the practical
course and the seminar is required to reach the study
objectives of the module. The teaching staff will inform
about further details at the beginning of the courses.
Admission requirements for the
module examination
Requirements for the award of
Protocols for the practical course in a group of two (70%),
credit points (forms of examination,
seminar presentation (30%)
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
MMLS.A16
Symbiosis, signalling and metabolism
Sasso
at least 1 successfully completed Basic module
Specialisation module , Project module, Master thesis
Compulsory elective module, Advanced module
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
10 cp
Yearly, SS
1 semester
V: 1 hpw
P: 5 hpw
S: 1 hpw
-105 h
-195 h
This module discusses selected topics from symbio-sis,
signalling and metabolism in plants and microor-ganisms,
including the mutualism between leguminous plants and
rhizobia, interactions between microalgae and bacteria, G
protein-coupled receptors and calci-um signalling, and the
metabolism of carbohydrates, phenylpropanoids and
terpenes including involved enzymes in land plants. In the
practical course, stu-dents can participate in an ongoing
project of the re-search group.
Learning and qualification objectives Basic knowledge and insights into current research
questions in the fields mentioned above; molecular and
microbiological laboratory methods for unicellular algae;
reading and assessment of the scientific prima-ry literature
and seminar talk on a selected article. Regular
participation in the practical course and the seminar is
required to reach the study objectives of the module. The
teaching staff will inform about further details at the
beginning of the courses.
Admission requirements for the
Writing of a practical course protocol.
module examination
Requirements for the award of
Oral or written examination (70%), Seminar presentation
credit points (forms of examination,
(30%), major course assessment for the practical course
weighting of grades in %)
(protocol)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
MMLS.T1
Specialisation module MMLS
Supervisor (Theißen, Baniahmad, Jungnickel, Englert,
Schuster, Mittag, Sasso, Spänkuch, Görlach, Heinemann,
Oelmüller, Bolz, Lehmann)
at least 2 Basic modules and 2 Advanced modules
Master thesis
Compulsory module
Every semester (WS, SS)
1 semester (half of the semester, the whole day)
practical course
10 cp
- 230 h
- 70 h
The module provides a specialisation in current methods
on special topics of MLS.
Learning and qualification objectives Development of special techniques
Admission requirements for the
none
module examination
Requirements for the award of
Oral examination (ca. 15 min) 100%
credit points (forms of examination,
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
MMLS.T2
Project Module MMLS
Supervisor (Theißen, Baniahmad, Jungnickel, Englert,
Schuster, Mittag, Sasso, Spänkuch, Görlach, Heinemann,
Oelmüller, Bolz, Lehmann)
at least 2 Basic modules and 2 Advanced modules
Master thesis
Compulsory module
Every semester (WS, SS)
1 Semester (half of the semester, the whole day)
practical course
20 cp
- 470 h
- 130 h
The module deepens knowledge of selected research
areas and provides technical preparation of the Master
thesis. It is guided research work including the preparation
of literature data and experimental work on a special topic
of MLS, which is integrated into the current research
works of the offering institution.
Learning and qualification objectives Focus on specific research work; planning experiments;
setting up a work schedule; methodology of data
collection; analysis of molecular biological data; recordkeeping of scientific work
Admission requirements for the
none
module examination
Requirements for the award of
Presentation (100 %)
credit points (forms of examination,
weighting of grades in %)
Module number
Module name
Module coordinator
Admission requirements
Usability (required for)
Type of module (compulsory,
compulsory elective module)
Frequency of offer (module cycle)
Duration of module
Module composition/ Forms of
instruction (lecture, seminar,
exercise, practical course)
Credit points (ECTS credits)
Workload in hours:
- in class and
- self-study (incl. examination
preparation)
Contents
MMLS.T3
Master thesis MLS
Supervisor (Theißen, Baniahmad, Jungnickel, Englert,
Schuster, Mittag, Sasso, Spänkuch, Görlach, Heinemann,
Oelmüller, Bolz, Lehmann)
successful completion of the Modules MMLS.T1 and
MMLS.T2
Compulsory module
Yearly (WS, SS)
1 Semester
practical course
30 cp
- 700 h class hours
- 200 h self-study
The Master thesis shall prove that the student is able to
handle a scientific problem within 6 months using scientific
methods. The topic of the Master thesis is supervised by
one of the module-coordinators and has to be agreed with
this person. A high value is set particularly on thoroughly
data collection, analysis and interpretation. Experience in
an independent writing of a scientific work is gained during
the module. The module guides to an independent
scientific work on own responsibility.
Learning and qualification objectives Setting up a work schedule; independent experiment
planning and analysis as well as writing a scientific paper
Admission requirements for the
None
module examination
Requirements for the award of
Master thesis (100 %)
credit points (forms of examination,
weighting of grades in %)