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BIO 241 – EXAMINATION #4 THE DIGESTIVE SYSTEM READ THESE DIRECTIONS TEST #_______ BEFORE STARTING THE TEST, 1. Write your name and test number at the top of the scantron sheet. 2. Fill in the bubbles for your name (last, first) on the back of the scantron sheet. 3. Write your name on the front of the written answer sheet. TURN IN YOUR SCANTRON SHEET AND WRITTEN ANSWER SHEET. YOU MAY KEEP THE REST OF THE TEST. THE ANSWER KEY WILL BE POSTED ON MY WEBSITE. YOU MUST TURN IN THE TEST 10 MINUTES BEFORE THE HOUR. THERE WILL BE NO EXCEPTIONS. REMEMBER THE ACADEMIC HONOR CODE pledge you took below: “As a student at The University of North Carolina Wilmington, I am committed to honesty and truthfulness in academic inquiry and in the pursuit of knowledge. I pledge to uphold and promote the UNCW Student Academic Honor Code.” __________________________________________________________________________________ Each of the following questions or incomplete statements below is followed by suggested answers or completions. Select the one BEST answer in each case and fill in the appropriate circle on the computer sheet. (2 points each) 1. Of the listed layers, which one would be pierced thirdly by the point of a pin passing from the outside of the esophagus towards the lumen? A. Circular smooth muscle D. Longitudinal smooth muscle B. Lamina propria E. Epithelium C. Adventitia 2. Each of the following lists some of the tissue layers of the digestive tract. Which one has them order from lumen to external surface? A. lamina propria, muscularis mucosae, submucosa, muscularis externa, serosa B. serosa, lamina propria, submucosa, muscularis mucosae, muscularis externa C. mucosa, submucosa, muscularis mucosae, muscularis externa, lamina propria D. mucosa, muscularis mucosae, submucosa, muscularis externa, lamina propria E. mucosa, submucosa, muscularis externa, lamina propria, serosa in correct 3. The ___________ regulates digestive tract motility, secretion, and blood flow and its neurons are found in the ____________. A. autonomic nervous system; serosa B. central nervous system; muscularis externa and muscularis mucosae C. enteric nervous system; submucosa and muscularis externa D. visceral sensory division; muscularis externa and submucosa E. visceral motor division; mucosa and submucosa 4. In which portions of the gastrointestinal tract would you expect to find stratified squamous epithelium? A. Stomach and small intestine. D. Colon and anal canal. B. Esophagus and stomach. E. Small intestine and large intestine. C. Esophagus and anal canal. 5. Hydrochloric acid is secreted by _____ located at the _____ of the gastric glands. A. Chief cells; upper one-third D. G cells; very bottom B. Parietal cells; middle one-half E. Mucous cells; top one-quarter C. Enteroendocrine cells; ends 1 6. Of the structures listed, which would be passed thirdly by bile moving from the gall bladder? A. Common hepatic duct. D. Duodenum B. Ampulla of Vater E. Cystic duct C. Common bile duct 7. A lacteal is a lymphatic capillary typically found in each: A. Plica circularis. D. B. Plica semilunaris. E. C. Nerve plexus. Microvillus. Villus. Which one of the following produces mucous? A. Duodenal (Brunner’s) glands B. Goblet cells. C. Salivary glands. All of the above produce mucous. None of the above produces mucous. 8. D. E. 9. Fill in the blanks to make the statement below correct. The external anal sphincter is formed from the ___________ and is controlled by the ________ spinal nerves. A. circular muscles of the muscularis externa; parasympathetic sacral B. skeletal muscles of pelvic diaphragm; sacral C. longitudinal muscles of the muscularis externa; vagus D. circular muscles of the muscularis externa; pelvic diaphragm E. skeletal muscles of the pelvic diaphragm; sympathetic sacral 10. The secretions of the pancreatic islets (insulin and glucagon) pass through the: A. Main pancreatic duct. D. Hepatopancreatic ampulla. B. Accessory pancreatic duct. E. Common bile duct. C. Blood stream. 11. Most of the blood flowing through the liver is oxygen-_____; it arrives to the liver via the _____. A. Poor; hepatic portal vein D. Rich; hepatic artery B. Poor; hepatic artery E. Rich; hepatic sinusoid C. Rich; hepatic portal vein 12. Assuming that the biliary system is completely empty and that the hepatopancreatic sphincter (of Oddi) closed, which of the following structures listed would be passed thirdly by bile after it is produced by hepatocytes? A. Bile canaliculi D. Common bile duct B. Right or left hepatic duct E. Cystic duct C. Bile duct 13. Which aspect of deglutition is voluntary? A. Movement of food into the pharynx B. Movement of food through the pharynx C. Movement of food into the esophagus D. Movement of food through the esophagus E. More than one of the above is voluntary. 14. Which one of the following is not correct concerning the stomach? A. Food entering the stomach remains in the body (corpus) for an extended time. B. In an empty stomach the rugae are visible. C. The actions of the stomach produce a thin liquid paste known as chyme. D. The pyloric sphincter remains open at all times. E. The gastroesophageal sphincter remains tightly closed almost all the time. 15. Mixing of chyme with digestive juices in the small intestine is achieved by: A. Deglutition. D. Haustral churning B. Mixing waves. E. Segmentation. C. Peristalsis. 2 16. Amino acids and monosaccharides are absorbed in the ____________, and fatty acids are absorbed in the _______________. A. small intestine; large intestine B. small intestine; liver C. stomach; small intestine D. stomach; large intestine E. small intestine; small intestine too 17. Which of the following initiates the enterogastric reflex? A. The first portion of the deglutition reflex B. Stretch of the stomach by incoming food C. Stretch of the duodenum by incoming chyme D. Stretch of the cecum by incoming chyme E. Stretch of the rectum by incoming fecal matter 18. _____________ is associated with food stretching the stomach and activating myenteric and vagovagal which in turn stimulate gastric secretions. A. The cephalic phase B. The gastric phase C. The intestinal phase D. The gastrointestinal phase E. The mesenteric phase 19. Which one of the following would act to slow the motility of the small intestine? A. Distension of the small intestine D. All of the above inhibit motility. B. Parasympathetic neural activity E. None of the above inhibits motility. C. Gastroileal reflex. 20. Which of the following would increase the rate of material movement into the cecum and large intestine? 1. Enterogastric reflex 2. Gastroileal reflex 3. Gastrin A. B. C. 1 only 2 only 3 only D. E. reflexes, 1 and 2 only 2 and 3 only 21. Which of the following is not correct? A. Peristalsis occurs throughout the length of the colon. B. Movement of materials through the colon is slower than in the small intestine. C. The rectum is almost always full of feces. D. Food in the stomach increases colonic motility. E. Gastrin increases colonic motility. 22. Which of the following is not true concerning the defecation reflex? A. Is controlled by the medulla as a part of the vagus nerve B. Can be initiated by a specialized action called mass movement C. Is assisted by contraction of the skeletal muscles of the anterolateral abdominal wall D. More than one of the above is not true. E. All of the above are true statements concerning the defecation reflex. 23. Which one of the following is true of salivary amylase? A. Its optimum pH range is around 8.2. B. It breaks the bonds between starch molecules, resulting in the disaccharide maltose. C. It is able to continue its digestive function until the food is converted to chyme and passed into the duodenum. D. It actively works to breakdown carbohydrates, fats, and proteins, as long as it remains in the mouth. E. All of the above are true statements. 3 24. Which one of the following produces mucous as well as considerable other secretions? A. Pancreatic acinar cells D. Goblet cells B. Esophageal glands E. Gastric glands C. Hepatocytes 25. Which one of the following is not true of the gastric phase of gastric activity? A. It is stimulated by the presence of food in the stomach. B. The hormone secretin is released. C. There is increased flow of digestive juices from the gastric glands. D. The hormone gastrin is released. E. There is increased motility in the small intestine. 26. Which of the following enzyme types would be associated with the brush border? A. Lipases D. All of the above B. Disaccharidases E. None of the above C. Dipeptidases 27. The role bile plays in the digestive process is to: A. Attach fat-digesting enzyme to globs of dietary fat. B. Break globs of dietary fat into small particles for easier chemical digestion. C. Slow peristalsis in the small intestine, thus giving the lipase enzymes sufficient time to break the bonds of the fat molecules. D. Release the energy stored within the bonds of fast molecules. E. Do none of the above. 28. The vast majority of water absorption occurs: A. In the stomach since virtually none of the foodstuffs are absorbable yet. B. In the duodenum, where chyme is mostly water due to the presence of gastric juice, pancreatic juice, and biliary juice. C. In the ileum, since this is where 90% of foodstuff absorption occurs. D. In the large intestine, since most of the absorbable molecules have already been absorbed and the only thing left to absorb in water. E. In the rectum, since fecal material sits there longest without moving. 29. In the blood of the hepatic portal vein you would expect to find high concentrations of: A. Monosaccharides and amino acids. D. Monosaccharides, amino acids, and fats. B. Monosaccharides and fats. E. None of the above until the blood C. Amino acids and fats. leaves the liver. 30. Arrange these events in the order in which they occur during fat digestion, absorption, and transport in the small intestine: 1. chylomicrons enter lacteals 2. triglycerides, phospholipids and cholesterol coated with protein 3. fatty acids and glycerol packaged into micelles 4. bile salts emulsify fats 5. lipase digests fat A) 4,5,2,3,1 B) 2,5,4,3,1 C) 3,5,4,1,2 D) 4,5,3,2,1 E) 5,3,4,1,2 4 For each of the following groups, match the term at the top with the phrases that follow. There is only one answer per phrase. A choice may be used once, more than once, or not at all. Place answers on written answer sheet (2 points each) Group 1 A. B. C. Enterogastric reflex Gastroileal reflex Gastrocolic reflex D. E. D31. Utilizes the vagus nerve E32. Results in increased gastric activity A33. Results in decreased gastric activity B34. Results in increased motility of the small intestine C35. Results in mass movement All None Group 2 A. B. C. D. E. cholecystokinin gastric inhibitory peptide secretin gastrin A, B, and C F. G. E36. Results in decreased gastric secretion and motility D37. Results in increased gastric activity F38. Hormone(s) produced by enteroendocrine cells C39. Stimulates release of Sodium Bicarbonate A40. Causes sphincter of Oddi to relax all none Group 3 A. B. C. procarboxypeptidase carboxypeptidase chymotrypsin G41. First to break down proteins D42. autocatalytic F43. Produced by small intestine C44. Converted product of chymotrypsinogen D. E. F. G. H. trypsin chymotrypsinogen enterokinase pepsin trypsinogen 5 Write the correct word on your written answer sheet for each of the definitions below. (1 point each) 45. The _submandibular_______ gland opens via a single duct at the base of the frenulum, central incisor. opposite the lower 46. The __fundus______ is the part of the stomach that bulges above the opening of the esophagus. 47. The __ileocecal or ileocolic sphincter_______ valve prevents backflow of intestinal contents from the large intestine into the small intestine. 48. The molecule that is required for the absorption of vitamin B12 is ____ intrinsic factor___. 49. The collection of a hepatic artery, bile duct and hepatic portal vein is called a hepatic _triad_____. 50. The serous membranes that suspend the stomach and intestines from the abdominal wall are called ____mesenteries____. 51. The muscle tone of the taenia coli along the colon contracts it lengthwise, causing its walls to bulge and form pouches called ___haustra_____. 52. The appendix is attached to the lower end of the _cecum______ of the large intestine. 53. During swallowing, the soft palate contracts to close the __ nasopharynx or nasal cavity__. 6 WRITTEN ANSWER SHEET Personal Return __________________ NAME_____________________ TEST #__________ Matching ( 2 pts each) Fill-in-the-Blank ( 1 pt each) 31. __D____ 36.__E____ 41. __G___ 45. _submandibular______________ 32. __E____ 37. __D____ 42. __D___ 46. _fundus______________ 33. __A____ 38. __F____ 43. __F___ 47. _ileocecal/ileocolic______________ 34. __B____ 39. __C____ 44. __C___ 48. _intrinsic factor______________ 35. __C____ 40. __A____ 49. _triad______________ 50. _mesenteries______________ 51. _haustra______________ 52. _cecum______________ 53. _nasopharynx/nasal cavity_________ 54. In this chapter, we discussed the importance of pH in controlling various aspects of digestion such as motility and the activity of enzymes. Pick from the choices below to decide which pH best controls each enzyme or event listed below. (3 points) A. pH < 2 B. pH >3 C. pH 6.5-7 D. pH >7.5 1. 2. 3. 4. 5. 6. pH at which lingual lipase will be first activated _A_____ pH produced by HCl __A____ chyme in the duodenum beginning with this pH will inhibit the gastric motility and secretion _A__ salivary amylase works best at this pH _C____ chyme in the duodenum beginning with this pH will stimulate gastric secretions _B_____ trypsin and pancreatic lipase work best at this pH _D____ TOTAL POINTS _____100____ POINTS MISSED ____________ POINTS SCORED ____________ TEST SCORE ___________% 7