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Unit 5 Cellular Replication GN #2 Meiosis Name: _____________________________ Slides # 36-70 Only two types of cells in sexually reproducing eukaryotes undergo MEIOSIS and these are the cells that generate SEX CELLS (Gametes) . Facts about Egg Cells in females: A human female is born with _________________________________________________________ Egg cells are generated through a process called_____________________________________ Each egg cell has only _____________________________________ and is called ______________________. Human egg cells have ________________________________. This reproductive cell is called a ______________________________. Facts about Sperm Cells in males: Sperm cells are made in the _____________________through a process called_________________________________ Sperm cells are derived from ____________________________________________________ Sperm cells have only ___________________________________________________ (23) and is called _____________. This reproductive cell is called a ________________________________. How can cells duplicate and yet wind up with only ½ the number of chromosomes??? MEIOSIS!!! Meiosis is very similar to __________________ WITHOUT ________________________ In Meiosis, 1 cell __________________________________called ____________________. When the two gametes come together (fertilization) the new cell is called a ___________________________ Gamete + Gamete=__________________________ It is important to start with HAPLOID CELLS (gametes) (1n) Fertilization is the union of a ________________ and ________________ creating a _______________________. The chromosome number is reduced in sperm and egg cells so at ____________________________________________ _____________________________________________________________________________. The process of meiosis:____________________________________________________, __________________________ ____________________________, _____________________________________________________ Each organism must inherit a _____________________________________________________ _____________________________________________________________________________. In Meiosis, the two sets of chromosomes are separated and each gamete winds up with one set! Slide#47 The two sets of chromosomes are said to be ________________________________________________. Human cells have 23 chromosomes from the egg (maternal) and 23 chromosomes from the sperm (paternal) =46 Chromosomes #s 1-23 + Chromosomes #s 1-23 = 46 (diploid) Humans have 23 PAIRS or a total of ___________________________ 2n=46 A homologous pair means the same Chromosome from each parent carrying the same genes The above is a duplicated chromosome, ready to go through the first meiotic division, the left from maternal and the right from paternal. =4n The first meiotic division will half the chromosome number to 2n=diploid The second meiotic division will then half the chromosome number again to 1n=haploid sperm and egg cell Phases of Meiosis: Meiosis I is a process of reduction division where the number of chromosomes per cell is ___________________________________________________________________________________________ ___________________________________________________________ Meiosis II the diploid cell has now divided again to produce 4 haploid cells Lets see how this happens: Meiosis I Interphase I: Cells undergo a round of ___________________________________________________ Cells are now 4n 92 chromosomes (human) Prophase I: Chromosomes pair with its homologous chromosome to form a ____________________ There are 4 ____________________________________________________ Duplicated chromosome 1 pairs up with duplicated chromosome 1 etc….. Chromatids exchange portions of their chromatids in a process called: _________________________________________________________________ Crossing over produces ____________________________________________!!!! This is how genes (traits) get exchanged!! VARIATION is created!!!! Metaphase I : Chromosomes line up opposite of their homologous pairs!!!! (THIS IS DIFFERENT THAN MITOSIS WHERE THEY LINE UP SINGLE FILE!!! Spindle fibers _________________________________________ Anaphase I: The fibers separate ___________________________________________ DUPLICATED CHROMOSOMES SEPERATED (not CHROMATIDS LIKE MITOSIS) Telophase 1 and Cytokinesis: Nuclear membranes form. The cell_______________ ________________________________. The two cells _____________________________________________________________ _______________________________________________________________________ The two new cells are now 2n………..split of the 4n into 2 cells = 2n. both new cells have 46 chromosomes (human) with blended genes.! MEIOSIS II The two cells produced in Meiosis 1 now enter another __________________________________ These 2 new cells DO NOT GO THROUGH _________________________________!! Each of the ______________________________________________________________. Meiosis II is JUST LIKE MITOSIS!!!! Prophase II: Centrioloes ________________________________________ No duplication of chromosomes!!! Metaphase II: Chromosomes line up _____________________________, single file! Anaphase II: __________________________________________________ (chromosomes pulled apart at middle) Telophase II and Cytokinesis: Meiosis results in ________________________ Gamete formation is different for males and females. In male animals, meiosis results in _______________ __________________________________________ In Female animals, only _____________________ The other 3 cells, __________________________ _________________________________________ Meiosis reduces _________________________________________ ________________________________________________________ ________________________________________________________ The first division, ________________________________________ _____________________________________________________ The second division, _____________________________________ ______________________________________________________ Please fill in the chart: Differences between Mitosis and Meiosis Mitosis Cell Type of Parent (2n or n) Number of DNA replications Number of times cell divides Involves pairing of homologous chromosomes Crossing over and sharing of genes Involves only splitting of sister chromatids Involves separating homologous chromosomes and then splitting of sister chromatids Cell type of daughter cells (2n or n) Number of daughter cells produced Genetic relationship of daughter cells To parent and to each other (Identical or Unique) Number of cell divisions STOP PPT AT SLIDE #70….will do the rest in semester 2 Meiosis Questions to answer after writing your notes: 1). Fertilization results in a). a zygote. b). a diploid cell. c). a cell with a new genetic combination. d). All of these are correct. 2). The diploid number of chromosomes in humans is 46. The haploid number is a). 138. b). 92. c). 46. d). 23. 3). After chromosome replication and during synapsis, a). homologous chromosomes pair along their lengths. b). sister chromatids pair at the centromeres. c). homologous chromosomes pair at their ends. d). sister chromatids pair along their lengths. 4). During which stage of meiosis does crossing over occur? a). prophase I b). anaphase I c). prophase II d). telophase II 5). Synapsis is the process whereby a). homologous pairs of chromosomes separate and migrate toward a pole. b). homologous chromosomes exchange chromosomal material. c). homologous chromosomes become closely associated. d). the daughter cells contain half of the genetic material of the parent cell. 6). Which of the following occurs during anaphase I? a). Chromosomes cluster at the two poles of the cell. b). Crossing over occurs. c). Chromosomes align down the center of the cell. d). One version of each chromosome moves toward a pole. 8). Mitosis results in two ________ cells, while meiosis results in _______ haploid cells. a). haploid/four b). diploid/two c). diploid/four d). haploid/two 9). Genetic diversity is greatest in b). sexual reproduction. c). asexual reproduction. d). binary fission. 10). An organism has 56 chromosomes in its diploid stage. Indicate how many chromosomes are present in the following, and explain your reasoning: a). somatic cells b). metaphase (mitosis) c). metaphase I (meiosis) d). metaphase II (meiosis) e). gametes 11. What is the difference between metaphase I and Metaphase II?_______________________________________ _____________________________________________________________________________________________ ______________________________________________________________________________________________ 12. What is the difference between Anaphase I and Anaphase II?________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ 13. Which stage of Meiosis (I or II) is most like Mitosis? EXPLAIN:________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ 14. What is a tetrad?______________________________________________ _________________________________________________________________ 15. What are homologous chromosomes?_________________________________ ___________________________________________________________________ ___________________________________________________________________ 16. Do homologous chromosomes have the same number of genes?_____________ Do they carry identical genes? EXPLAIN_________________________________ ____________________________________________________________________ ____________________________________________________________________ 17. Explain why crossing over (synapsis) leads to exchange of genetic information. ________________________________________________________________________ __________________________________________________________________________ _________________________________________________________________________________ 18. A muscle cell of a mouse contains 22 chromosomes. Based on this info, how many chromosomes are there in the following types of mouse cells? a. daughter muscle cell formed from mitosis_________________________ b. Mouse egg cell_______________________________________________ c. fertalized egg cell of mouse_____________________________________ 19. When meiosis occurs in females, the cytoplasm is not divided equally among the resulting four cells. Explain why? ____________________________________________________________________________________________________ ___________________________________________________________________________________________________ 20. During which phase of the meiotic cell cycle does DNA replication occur?_____________________________ 21. A human cell containing 44 autosomes and one X and one Y chromosomes is: a. a somatic cell of a male b. a sperm cell c. an egg cell d. a somatic cell of a female 22. What is the name for a complete set of chromosomes of an organism arranged and displayed in pairs and ordered by size?_______________________________________________ 23. Which 2 cells would be more genetically similar to each other? a. 2 gametes produced by the same person b. 2 somatic cells produced by the same person c. 2 eggs produced by the same woman d. 2 sperm produced by the same man.