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ADRENAL RESPONSE®
[Restoring Deeper Connections]
Adrenal Response®
Daily adrenal support for maintaining healthy
cortisol levels and a healthy stress responseu
• 250 mg of Sensoril, a patented extract of Ashwagandha root and leaf clinically shown to address negative effects
of chronic stressu
• Additional adaptogenic herbs Holy Basil, Rhodiola, and
Astragalus provide synergistic support for healthy inflammatory and stress reactionu
• Glandular-free, vegetarian-safe formula
40105 - 90 tabs
40096 - 60 tabs
40119 - 90 tabs
Ample evidence suggests that eating a typical modern diet, which often consists of excess sugars and carbohydrates, presents significant challenges to
optimal wellness. Coupled with the effects of chronic stress, this can lead to poor adrenal function and a cascade of physiological effects in the body
ranging from gastrointestinal issues to chronic fatigue and inflammation.1,2,3 We now know that even lower levels of stress, when regularly occurring,
can induce a similar detrimental effect in the body as strenuous athletic overtraining.4 When our bodies feel under threat, the HPA Axis, which
regulates our physical reaction to stress over adjusts and triggers elevated cortisol levels. In a recent study, it was discovered that these elevated levels
can overtime can lead to a suppressed immune system, and induce glycogenolysis, and insulin resistance.5 Without proactive treatment and support,
these issues may eventually require aggressive strategies to correct. In addition to dietary changes and adopting stress management techniques,
ongoing maintenance of the adrenal system is recommended.
u
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
INNATE Response™ offers two Adrenal Response formulas to
provide multi-level support:
• Adrenal Response® addresses chronic stress by supporting energy
levels and supporting an overworked nervous system.u
• Adrenal Response® Complete Care further addresses chronic stress by
supporting adrenal tissue and appropriate hormone output. Our patented
formula assists with FoodState® Vitamins C, B5, Magnesium and L-Serine
to nourish tissue as well as provide adaptogenic support.u
[Restoring Deeper Connections]
Botanical Support:
Adrenal Response® and Adrenal Response® Complete Care contain a full range of
adaptogens including Ashwagandha, Holy Basil, Rhodiola and Astragalus. Use of
adaptogenic herbs for adrenal system maintenance has gained recent attention
from several studies that support their stress-protective effects.u
Sensoril®† Ashwagandha is a clinically researched extract of Withania somnifera and the only
form of Ashwagandha that is standardized to 8% withanolides. A 2008 multiphase, doubleblind placebo controlled human clinical trial validated its ability to reduce experiential
feelings of stress and anxiety, decrease serum cortisol and C-reactive protein levels, and
increase serum DHEA levels in a dose-dependent manner.6 Subjects given the highest dose
of 250 mg of Sensoril also saw added support for cardiac health and maintenance of healthy
glucose response.u
Additional Adaptogenic herbs:
Holy Basil (Ocimum sanctum) is a plant revered in the Ayurvedic tradition for its support
of the stress response.u Also known as Tulsi, it is backed by current research including a
2014 study showing that it addresses physical, chemical, metabolic and psychological stress
through unique pharmacological actions.7u
Tulsi protects organs and tissues from chemical stress found in industrial pollutants and
heavy metals, and supports a healthy response to physical stress from prolonged physical
exertion.
Adrenal Response® also contains whole body primary adaptogens Rhodiola and Astragalus offering a synergistic effect that eliminates the need for
glandular herbal support.8 Rhodiola rosea has wide ranging and varied historical uses dating back to the Ancient Greeks. Modern research shows it
supports a healthy mood by balancing the parasympathetic nervous system responses* and, as an adaptogen, strengthening the body’s response to
physical, emotional and mental stress.9,10u
Astragalus is considered one of the most important herbs in Chinese medicine. In a 2013 study, it was shown to offer broad protective effects. It is
particularly prized for its flavonoids, polysaccharides and triterpene glycosides, which are known to support a healthy immune system.11u Schisandra
berry, is an antioxidant rich fruit that was found in a 2013 study to support energy and stamina levels.u12
Both formulas are glandular free and Vegetarian Safe: Tested free of soy, dairy, gluten, herbicides and pesticides, with a formula of adaptogenic herbs,
now known to play an important role in adrenal health. Additional Support in Adrenal Response® Complete Care from FoodState Nutrients™
Sources:
1
A Moshfegh et al. What We Eat in American NHANES 2005-2006, Usual Nutrient Intakes from Food And Water Compared to 1997 Dietary Reference Intakes for Vitamin D, Calcium,
Phosphorus, and Magnesium, USDA, Agricultural Research Service. http://www.cdc.gov/nchs/nhanes/
Berz MD, J. Diet and the Prevention of Chronic Disease. Medscape Public Health, (August 21, 2012) http://www.medscape.com/viewarticle/769218
2
Bhatia V, Tandon RK. Stress and the gastrointestinal tract. J Gastroenterol Hepatol. 2005 Mar;20(3):332-9. Review.
3
Hackney A. Stress and the neuroendocrine system: the role of exercise as a stressor and modifier of stress. Expert Rev Endocrinol Metab. 2006 Nov 1; 1(6): 783–792.
4
Luccassan E, Cizza G. The Hypothalamic-Pituitary-Adrenal Axis, Obesity, and Chronic Stress Exposure: Sleep and the HPA Axis in Obesity. Curr Obes Rep. 2012 Dec; 1(4): 208–215
Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study. JANA, 11(1), 2008: 50-56.
5
JCohen MM. Tulsi - Ocimum sanctum: A herb for all reasons. J Ayurveda Integr Med. 2014 Oct-Dec;5(4):251-9.
6
Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration. Phytother Res. 2005 Oct;19(10):819-38.
7
Ibid. Phytother Res 2005.
8
EM Olsson et al. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med. 2009 Feb;75(2):105-12.
9
A Pannosian. Adaptogens in Mental and Behavioral Disorders, Psychiatric Clinics of North America. 2013 Mar;36(1); 49-64.
10
S. Ren S, et al.. Pharmacological effects of Astragaloside IV: a literature review. J Tradit Chin Med. 2013 Jun;33(3):413-6.
11
Koncic MZ, Tomczyk M. New insights into dietary supplements used in sport: active substances, pharmacological and side effects. Curr Drug Targets. 2013 Aug;14(9):1079-92
† Biswajit A. et al. Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind,Randomized, Placebo-Controlled Study. JANA, 11(1), 2008: 50-56.
u
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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© FoodState, Inc. 2016
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