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Clinical algorithm for the approach to pts with community-acquired infectious diarrhea or bacterial food poisoning. Key to superscripts: 1. Diarrhea lasting >2 weeks is generally defined as chronic; in such cases, many of the causes of acute diarrhea are much less likely, and a new spectrum of causes needs to be considered. 2. Fever often implies invasive disease, although fever and diarrhea may also result from infection outside the GI tract, as in malaria. 3. Stools that contain blood or mucus indicate ulceration of the large bowel. Bloody stools without fecal leukocytes should alert the laboratory to the possibility of infection with Shiga toxin–producing enterohemorrhagic Escherichia coli. Bulky white stools suggest a small-intestinal process that is causing malabsorption. Profuse "rice-water" stools suggest cholera or a similar toxigenic process. 4. Frequent stools over a given period can provide the first Source: Infectious Diarrheas, Harrison's Manual of Medicine, 18e warning of impending dehydration. 5. Abdominal pain may be most severe in inflammatory processes like those due to Shigella, Campylobacter, and Citation: Longo DL, Faucimuscle AS, Kasper DL,caused Hauserby SL, Jamesonloss, J, Loscalzo J. Harrison's Manual 18e; 2014 Availableinat: necrotizing toxins. Painful abdominal cramps, electrolyte can develop in severe cases of of Medicine, cholera. Bloating is common giardiasis. http://mhmedical.com/ Accessed: May 11, 2017 An appendicitis-like syndrome should prompt a culture for Yersinia enterocolitica with cold enrichment. 6. Tenesmus (painful rectal spasms with a strong Copyright © 2017 McGraw-Hill All rights urge to defecate but little passage of stool) Education. may be a feature of reserved cases with proctitis, as in shigellosis or amebiasis. 7. Vomiting implies an acute infection (e.g., a toxin-mediated illness or food poisoning) but can also be prominent in a variety of systemic illnesses (e.g., malaria) and in intestinal obstruction. 8.