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L.V.A.D Hope for the broken heart Kristen Highland Dietetic Intern June 6, 2011 OUTLINE Background on heart function and failure What is an LVAD? Introduction to TW Timeline of hospital stay Assessment Diagnosis Intervention Monitoring & Evaluation Where is TW now? Summary/Discussion Normal Heart Function Circulates blood throughout the body to tissues and organs Ejection Fraction (EF): measure of the % of blood ejected from the heart with each heartbeat Normal EF = 50-70% HEART FAILURE Progressive condition in which damage to the heart causes weakening of the cardiovascular system 2 main causes: CAD and MI Affects 5 million Americans Causes an average of 250,000 deaths in the US per year Dx: EF <40% STAGES OF HEART FAILURE Class I (Mild): no limitation of physical activity Class II (Mild): Slight limitation of physical activity. May cause fatigue, palpitation, or dyspnea. Class III (Moderate): Significant limitation of physical activity. Less than normal activity causes fatigue, palpitation, or dyspnea. Class IV (Severe): Any physical activity causes discomfort. Symptoms of cardiac insufficiency at rest WHAT IS AN L.V.A.D??? Left Ventricular Assist Device Mechanical circulatory device used to partially or completely replace the function of a failing heart 4 main parts: pump, power supply cord, controller, and power pack REASONS FOR USE 1. 2. 3. Bridge to Recovery (temporary)- after heart attack, heart surgery, or other debilitating shock to the heart Bridge to Transplant (long-term)- to keep patient alive until donor heart becomes available Destination Therapy (long-term)- for patients who don’t qualify for a heart transplant d/t cancer, CKD, or another lifeshortening condition NUTRITIONAL COMPLICATIONS Anorexia Delayed Gastric Emptying Nausea Early satiety Hyperglycemia Cardiac Cachexia Cardiac Cachexia Cachexia: Complex metabolic syndrome associated with underlying illness and characterized by loss of muscle with or without loss of fat mass Cardiac Cachexia: Caused by an anaboliccatabolic imbalance with a shift toward catabolism -increased cortisol and epinepherine -activation of the renin-angiotensinaldosterone axis Meet TW Male, 48 years old Med hx: HTN, dyslipidemia, infected groin abscess (requiring surgical excision x2), ongoing tobacco use Social hx: Married truck driver, hx. of drinking 6 beers/day (quit 1 month ago), currently smokes at least 1PPD of cigarettes, no current illicit drug use Dx: SOB, diastolic dysfunction (EF 15-20%) Anthropometrics Height: 5’ 7” Admit weight (4/8): 78.1 kg BMI: 27 IBW: 67.3 kg %IBW: 116 Food/Nutrition Related History Wife reports good appetite at home Food choices not necessarily the healthiest No known food allergies Home Medications -Lipitor -Aspirin -Lasix -Oxycodone -Augmentin -Nicotine patch -Vitamin C Physical Findings Slightly overweight, middle-aged male Some peripheral edema No signs of muscle wasting in temples or extremities unhealed groin abscesses Day 1-2 (4/8-4/9) Cardiac work-up Plan for diuresis with lasix drip Potassium and Magnesium repleted as needed TW states he is feeling better Medications Clorazepate Hydrocodone Naloxone Aspirin Colace Insulin (Humalog) Vancomycin Acetaminophen Oxycodone Morphine Lasix Labs 4/8 Lab Name Results Ref. Range Sodium 132 mmol/L (L) 135-144 mmol/L Potassium 3.8 mmol/L 3.7-5.5 mmol/L Chloride 93 mmol/L (L) 99-110 mmol/L Glucose 124 (H) 60-99 mg/dL BUN 7 mg/dL 6-23 mg/dL Creatinine 0.67 mg/dL 0.60-1.30 mg/dL Calcium 9.2 mg/dL 8.3-10.4 mg/dL Hematocrit 38.6% (L) 40.0-53.0% Hemoglobin 13.4 g/dL (L) 13.5-17.7 g/dL Day 5 (4/12) Wt: 76.3kg (1.8kg loss) Heart Catheterization and Coronary Angiogram Total occlusion of left main coronary artery NYHA Class IV systolic and diastolic heart failure Day 6 (4/13) Wt: 73.2 kg Surgery: Coronary Artery Bypass Graft x2 Unable to be weaned from bypass Placement of 1st LVAD: Temporary Tandem Heart Intubated and sedated with Propofol Coronary Artery Bypass Graft Day 7 (4/14) First Assessment Screened TW d/t Albumin 2.8 Albumin likely secondary to surgery No nutrition diagnosis or intervention performed at this time Day 9 (4/16) Wt: 80.4kg Still intubated and sedated NPO x 4 days Dobutrex, Epi, vasopressin off Weekend RD determined TW was at risk for Malnutrition TPN started: -Unhealed groin wounds -wanted to decrease stool output TPN Order Penn State (VE=10.5, temp=36.9) Req: 1730 kcals, 75-88g PRO 275 g Dextrose 100g Amino Acids No lipids added -Propofol providing 462 kcals from fat Labs 4/17 Lab Name Results Ref. Range Sodium 138 mmol/L 135-144 mmol/L Potassium 4.0 mmol/L 3.7-5.5 mmol/L Chloride 111 mmol/L (H) 99-110 mmol/L Glucose 101 mg/dL (H) 60-99 mg/dL Phosphorus 4.1 mg/dL 2.3-4.7 mg/dL Magnesium 1.9 mg/dL 1.7-2.5 mg/dL Albumin 2.4 g/dL (L) 3.2-4.9 g/dL Prealbumin 6.0 mg/dL (L) 18.0-32.0 mg/dL Day 11 (4/18)… THE BIG DAY!!! Determined that TW would need long term left ventricular mechanical assistance 4/17: Family meeting to discuss Heart Mate II LVAD 4/18: Surgery to remove Tandem Heart and implant Heart Mate II -Prealbumin = 7 Day 14 (4/21) Evening 4/20: -TW extubated -Propofol is discontinued 4/21: Received consult to begin TF Albumin = 2.8 Nutrition Diagnosis Inadequate ProteinEnergy intake R/T post surgery status, AEB extended NPO x 9 days Intervention What would YOU do??? TW’s Needs A.S.P.E.N. Guidelines Calories 1.) Mifflin x 1.1 A.F = 1716 kcals 2.) 25kcals x 73.2kg = 1830 kcals * Estimated needs = 1800 kcals/d Protein - 1.2-1.4g/kg for wound healing *Estimated needs = 88-102g/d TF Regimen (started 4/21) Formula: Perative (High Kcal/High PRO) Goal Rate: 60 mL/hr x 24 hrs -Start @ 15 mL/hr, increase Q8 hours to goal 1872 kcals, 96g PRO, 1138 mL water Flushes: 360 mL (60 mL Q4 hours) Total water: 1498 mL MONITORING & EVALUATION Calorie Count (4/23) Diet Order: Mechanical Soft, Ensure TID Intake: -1016 kcals -54g PRO -56% kcal requirements -66% PRO requirements *Still on TF Calorie Count (4/24) Diet Order: Diabetic, 2g Na, 300 mL trays Intake (only breakfast & lunch): -822 kcals -37g PRO -39% kcal requirements -39% PRO requirements Calorie Count (4/25) Needs increased to 2100-2200 kcals/d and 1.3-1.4g PRO/day Calorie count -1055 kcals -60g PRO -50% kcal requirements -63% PRO requirements TF discontinued -tolerating diet advancement -appetite slowly increasing - willing to drink Ensure to meet PRO needs Coumadin and diet education provided to TW and spouse Day 20 (4/27) Prealbumin = 17 mg/dL Calorie Count d/c Eating 100% of meals Drinking Ensure TW reports “feeling so full”, but compliant with eating to meet PRO needs Wounds beginning to heal Moved from CRU to main cardiac floor “Nutrition problem resolved” Family advised to consult RD with any further questions The last few days 5/1 -intake = 1322 kcals -wt: 69.6 kg 5/2 -wt: 68.6 kg 5/4 -per nursing, eating 80-100% of meals -TW reports eating much better the past 2 days 5/5 -wt: 69 kg -wt. loss during stay likely related to diuresis Medications 5/2 Coumadin Aspirin Metoprolol Simvistatin Spironolactone Amoxicillin Colace Amiodarone Lisinopril Labs 5/5 Lab Name Sodium Potassium Chloride Glucose Calcium BUN Creatinine GFR Results 137 mmol/L 4.5 mmol/L 103 mmol/L 107 mg/dL (H) 9.3 mg/dL 11 mg/dL 0.54 mg/dL (L) >60 Ref. Range 135-144 mmom/L 3.7-5.5 mmol/L 99-110 mmol/L 60-99 mg/dL 8.3-10.4 mg/dL 6-23 mg/dL 0.60-1.3 mg/dL >=60 Plan for discharge Day 26 (5/3) -VAD Board meeting to discuss case -Pros/Cons of TW’s entire process Day 28 (5/5) -DISCHARGED! -Moved to Providence House BAD NEWS…. Readmitted to the hospital on 5/23 - recurrent unhealed groin abscess -surgery on 5/25 for drainage of abscess -d/c on 5/27 Summary 48 year old male Admitted with Class IV heart failure and unhealed groin abscesses Received long term Heart Mate II LVAD In need of TPN and TF post surgery Discharged once tolerating oral diet Readmitted on 5/23 for drainage of recurrent groin abscesses d/c again on 5/27 Hope for the best! References Hsich E, Wilkoff B. “Diseases & Conditions” Cleveland Clinic C.C., Aug. 2010, Web. 29 May 2011. http://my.clevelandclinic.org/heart/disorders/heartfailure/ejectionfraction.aspx McClave S, et al. “Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)” Journal of Parenteral and Enteral Nutrition 33 (2009): 277-316. Romeo, et al. “Heart Failure” Heart Failure Online 2010, Web. 29 May 2011. http://www.heartfailure.org/eng_site/hf.asp Scurlock C, et al. “Impact of New Technologies on Metabolic Care in the Intensive Care Unit” Current Opinion in Clinical Nutrition and Metabolic Care 12 (2009): 196-200. Slaughter M, et al. “Clinical Management of Continuous-flow Left Ventricular Assist Devices in Advanced Heart Failure” The Journal of Heart and Lung Transplantation (2010): 1-39. Stahovich M, et al. “The Next Treatment Option- Using Ventricular Assist Devices for Heart Failure” Crit Care Nurs Q 30 (2007): 337- 346.