* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download 6th European Congress of Virology
2015–16 Zika virus epidemic wikipedia , lookup
Ebola virus disease wikipedia , lookup
Middle East respiratory syndrome wikipedia , lookup
West Nile fever wikipedia , lookup
Hepatitis C wikipedia , lookup
Orthohantavirus wikipedia , lookup
Human cytomegalovirus wikipedia , lookup
Marburg virus disease wikipedia , lookup
Influenza A virus wikipedia , lookup
Hepatitis B wikipedia , lookup
6th European Congress of Virology Complete Preliminary Programme (ECV 2016)) Lecture/Event 13:00 – 13:30 Chairpersons Opening Ceremony – Welcome Session Hall 1 - 2.Floor Klaus Überla, Erlangen, Germany Olaf Degen, Hamburg, Germany Antiviral drug development: Assessing the present, imagining the future Don Ganem, Emeryville CA, USA Strategies to manage herpesvirus drug-resistance Graciela Andrei, Leuven, Belgium Entry inhibition as a future therapeutic option to treat hepatitis B and hepatitis D virus infection Stephan Urban, Heidelberg, Germany Long-acting injectables for HIV therapy and prevention Paul Benn, London, UK Coffee Break Foyer D-G; Hall G, D and E - 2.Floor Marcus Altfeld, Hamburg, Germany Teunis B. Geijtenbeek, Amsterdam, The Netherlands Keynote: How viruses usurp the host cellular machineries to evade innate immune responses: The case of the restriction factor BST2/Tetherin and the HIV-1 protein Vpu Clarisse Berlioz-Torrent, Paris, France Keynote: HIV-1 evades innate sensing by a novel RNA sensor in dendritic cells Teunis B.H. Geijtenbeek, Amsterdam, The Netherlands Cytomegalovirus recruits the retromer complex to promote NEMO degradation by autophagy Elena Muscolino, Hamburg, Germany Human herpesvirus 6 downregulates the expression of activating ligands during lytic infection to escape elimination by natural killer cells Dominik Schmiedel, Jerusalem, Israel Antiviral activity of the cGAS-STING pathway against hepatitis B virus infection Seung-Ae Yim, Strasbourg, France Membranous fingerprinting of HIV-1 infected primary CD4+ T cells reveals virus-mediated dysregulation of a putative NK cell receptor Sandra Dehn, Tübingen, Germany Michael H. Malim, London, UK Julian Schulze zur Wiesch, Hamburg, Germany Keynote: HIV restriction - striking early Michael H. Malim, London, UK Requirements for initiation factors in the translation of hepatitis C virus Esther Gonzalez-Almela, Madrid, Spain Identification of potent restriction factors of hepatitis C virus infection and their contribution to viral species-tropism Richard J. P. Brown, Hannover, Germany Novel techniques for genome visualization reveal the fate of incoming adenoviral genomes against nuclear antiviral factors Tetsuro Komatsu, Bordeaux, France The antiviral protein viperin targets tick-borne encephalitis virus replication and assembly Kirstin Vonderstein, Umeå, Sweden 13:30 – 14:00 Plenary Session 1: The Future of Antiviral Therapy 14:00 – 14:30 14:30 – 15:00 15:00 – 15:30 15:30 – 16:00 Chairpersons 16:00 – 16:30 16:00 – 18:00 WS1: Innate Antiviral Immunity and Viral Immune Evasion 17:00 – 17:15 17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 Chairpersons 16:00 – 16:30 16:30 – 16:45 16:45 – 17:00 16:00 – 18:00 Wednesday, 19th October 16:30 – 17:00 WS2: Restriction Factors of Viral Infection 17:00 – 17:15 17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 Room Hall 1 – 2. Floor Time Hall 1 – 2. Floor Session Hall F – 2. Floor Period 13:30 – 15:30 Date * subject to change In vivo evasion of MxA reveals pandemic potential of emerging influenza A viruses Ebrahim Hassan, Freiburg, Germany SMARCA2 the ATPase subunit of the chromatin remodeling BAF complex is required for the antiviral activity of MxA Alexandra Dudek, Freiburg, Germany 6th European Congress of Virology Session Time Lecture/Event Chairpersons Dimitri Lavillette, Shanghai, China Urs Greber, Zurich, Switzerland Keynote: Insights into principles of virus entry and uncoating Urs Greber, Zurich, Switzerland Native structure of a retroviral envelope protein and its conformational change upon interaction with the target cell Christiane Riedel, Vienna, Austria Quantitative phospho-proteomics reveal new insights into signaling events triggered by influenza A virus infection Silke Stertz, Zurich, Switzerland The cytoskeletal adaptor protein obscurin-like 1 interacts with L2 and is required for HPV16 endocytosis Elena Wüstenhagen, Mainz, Germany The spike protein of the middle east respiratory syndrome coronavirus has sialic acid binding activity Ivy Widjaja, Utrecht, The Netherlands Quantification of the binding forces of Dengue virus with cell receptors at a single-virus level Yueh-Hsin Ping, Taiwan, Republic of China Switching to LAMP1 during cell entry of Lassa virus Ron Diskin, Rehovot, Israel Gabriella Campadelli-Fiume, Bologna, Italy Vincent Parissi, Bordeaux, France Keynote: Control of, and regulation by, the BKPyV miRNA Michael J. Imperiale, Ann Arbor MI, USA An enterovirus mutant that can replicate in the absence of replication organelles Frank van Kuppeveld, Utrecht, The Netherlands Chikungunya trans-replication systems as tools to study the properties of replicase proteins Tania Quirin, Helsinki, Finland Delineating the interplay between the PB2 protein of influenza A virus and the host ubiquitin proteasome system Elise Biquand, Paris, France Is replication fidelity of influenza A viruses modulated by a proofreading activity? Marion Declercq, Paris, France Single-molecule FISH reveals non-selective packaging of Rift Valley fever virus genome segments Paul Wichgers Schreur, Lelystad, The Netherlands Usp7, an ubiquitin specific protease, interacts with Merkel Cell polyomavirus large T-antigen and modulates viral DNA replication Manja Czech-Sioli, Hamburg, Germany 16:00 – 16:30 16:00 – 18:00 16:30 – 16:45 16:45 – 17:00 WS3: Virus Attachment and Entry 17:00 – 17:15 17:15 – 17:30 17:45 – 18:00 Chairpersons 16:00 – 16:30 16:30 – 16:45 16:45 – 17:00 16:00 – 18:00 Wednesday, 19th October 17:30 – 17:45 WS4: Virus Replication Strategies 17:00 – 17:15 17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:15 – 19:00 ESV Junior Investigator Award 18:00 – 20:00 Poster Session – Scientific Networking Room Hall A – 1. Floor Period Hall B – 1. Floor Date * subject to change Hall 1 – 2. Floor Complete Preliminary Programme (ECV 2016)) 6th European Congress of Virology Session Time Lecture/Event Chairpersons Thomas Harrer, Erlangen, Germany Julian Schulze zur Wiesch, Hamburg, Germany Keynote: Mechanisms of HIV pathogenesis and HIV cure – insights from the paediatric HIV infection Philip Goulder, Oxford, UK Protein carbamoylation increases the restimulation of pp65-specific T cells in vitro Ralf Wagner, Regensburg, Germany Specificity and phenotype of T cells in primary human cytomegalovirus infection in pregnancy Daniele Lilleri, Pavia, Italy Sequence-function analysis of three T-cell receptors targeting the HIV-1 p17 epitope SLYNTVATL Christiane Mummert, Erlangen, Germany An immune-competent inbred mouse model of HCV-related rodent hepacivirus infection Eva Billerbeck, New York City NY, USA Identification of novel MHC I and MHC II restricted hepatitis D virus-specific peptide epitopes Johanna Blöcker, Hamburg, Germany Analysis of the adaptive cellular immune response to Nipah virus-like particles in C57BL/6 and Balb/c mice Sandra Diederich, Greifswald - Insel Riems, Germany Hans-Georg Kräusslich, Heidelberg, Germany Beate Sodeik, Hannover, Germany Keynote: Herpesvirus nuclear egress – elucidation of the prototypic vesicular nucleo-cytoplasmic transport Thomas Mettenleiter, Greifswald – Insel Riems, Germany Keynote: Host-catalyzed capsid assembly modulation: A new approach to anti-viral drug discovery Vishwanath R. Lingappa, San Francisco CA, USA A secretory pathway calcium ATPase regulates viral spread by modulating cellular proteolysis Hans-Heinrich Hoffmann, New York City NY, USA Incorporation of the influenza A virus NA segment does not require homologous non-coding sequences Sylvie van der Werf, Paris, France Proteomics of HCV virions reveals a surprising role for the nucleoporin Nup98 in virus morphogenesis Maria Teresa Catanese, London, UK Role of Rab33B and its autophagic Atg5/12/16L1 effector in hepatitis B virus morphogenesis Christina Bartusch, Mainz, Germany Elisabeth Puchhammer, Vienna, Austria René A.A. van der Vlugt, Wageningen, The Netherlands Keynote: Prospects for digital PCR in viral diagnostics Ward De Spiegelaere, Ghent, Belgium Infectious Laryngotracheitis virus (ILTV) vaccine intake evaluation by detection of virus amplification in feather pulps of vaccinated chickens Irit Davidson, Bet Dagan, Israel Influence of glycoprotein C on Bovine Herpesvirus-1 virion composition and implications for diagnostics Susanne Koethe, Greifswald - Insel Riems, Germany The immunoglobulin-like domain of HsFcµR (TOSO, FAIM3) binds IgM/ antigen immune complexes and can be used as a novel capture molecule in serological tests Christina Deschermeier, Hamburg, Germany 08:30 – 09:00 08:30 – 10:30 09:00 – 09:15 09:15 – 09:30 WS5: Adaptive Antiviral Immunity and Viral Immune Evasion 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 Chairpersons 08:30 – 09:00 08:30 – 10:30 09:00 – 09:30 WS6: Virus Maturation and Egress 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30 Chairpersons 08:30 – 09:00 08:30 – 10:30 Thursday, 20th October 10:15 – 10:30 09:00 – 09:15 WS7: Advanced Virus Diagnosis 09:15 – 09:30 09:30 – 09:45 Room Hall 1 – 2. Floor Period Hall F – 2. Floor Date * subject to change Hall A – 1. Floor Complete Preliminary Programme (ECV 2016)) 6th European Congress of Virology WS7: Advanced Virus Diagnosis Time Lecture/Event 09:45 – 10:00 Development of ELISA for detection of Seneca Valley virus exposure Zeynep Akkutay-Yoldar, Ankara, Turkey NS1-based anti-Zika virus ELISA revealed no cross-reactivity with other flavivirus infections or vaccination Katja Steinhagen, Lübeck, Germany Clinical evaluation of the Veris HCV assay for hepatitis C virus RNA quantification Laure Izquierdo, Villejuif, France Giorgio Palù, Padova, Italy Maria G. Masucci, Stockholm, Sweden Keynote: Viral interference with ubiquitin and UbL-regulated signaling pathways Maria G. Masucci, Stockholm, Sweden Th17, CCR6+ cells lack RNAses and are highly permissive to HIV infection: Implications for pathogenesis and therapy Alfredo Garzino Demo, Padova, Italy Bio-imaging of alphaviral disease in mice: A study using Ross River virus Essia Belarbi, Fontenay aux Roses, France Comparative analysis between flaviviruses reveals specific neural stem cell tropism for Zika virus in the mouse developing neocortex Cecile Khou, Paris, France Susceptibility and inflammatory response of human neural cells to Zika virus and West Nile virus infection Giovanna Desole, Padova, Italy Transcriptome analysis of human fetal astrocytes infected with Zika virus reveals dysregulation of genes required for brain development Daniel Limonta, Edmonton, Canada Pathogenesis of Zika virus infection in a non-human primate model Patricia Pesavento, Davis CA, USA 10:00 – 10:15 10:15 – 10:30 Chairpersons 08:30 – 09:00 08:30 – 10:30 09:15 – 09:30 WS8: Viral Pathogenesis 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30 10:30 – 11:00 Chairpersons 11:00 – 11:30 11:00 – 13:00 Thursday, 20th October 09:00 – 09:15 Plenary Session 2: Animal Models for Virus Research 11:30 – 12:00 12:00 – 12:30 12:30 – 13:00 13:00 – 15:00 Satellite Symposium 13:15 – 14:15 Room Hall A – 1. Floor Session Coffee Break Foyer D-G; Hall G, D and E - 2.Floor Marc Lütgehetmann, Hamburg, Germany Cesar Muñoz-Fontela, Hamburg, Germany Animal models to assess efficacy of infectious disease intervention: Ebola, CCHR and Influenza Miles W. Carroll, Salisbury, UK Human tumor virus infection and immune control in vivo Christian Münz, Zurich, Switzerland Animal models of viral hepatitis Alexander Ploss, Princeton NJ, USA Humanized mouse models for the study of viral pathogens and persistence J. Victor Garcia, Chapel Hill NC, USA Lunch Break Foyer D-G; Hall G, D and E - 2.Floor Hall 1 – 2. Floor Period QIAGEN-Symposium: “Novel Technologies for Improved Pathogen Detection“ Hall F – 2. Floor Date * subject to change Hall B – 1. Floor Complete Preliminary Programme (ECV 2016)) 6th European Congress of Virology Session Time Lecture/Event Chairpersons Florian Klein, Cologne, Germany Alexandra Trkola, Zurich, Switzerland Keynote: Virus, host and disease factors govern HIV-1 broadly neutralizing antibody induction Alexandra Trkola, Zurich, Switzerland Long-term immunogenicity of bivalent and quadrivalent human papillomavirus vaccines in the target population of organized vaccination programs Luisa Barzon, Padova, Italy Association of human IgG1 heavy chain variants on neutralization capacity and antibody dependent cellular cytotoxicity against HCMV Hannes Vietzen, Vienna, Austria HIV Env antibody can provide sterilizing immunity in the strictest sense Klaus Überla, Erlangen, Germany Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection Hadi Yassine, Doha, Qatar Structural basis of Zika virus cross-reactivity and cross-neutralization with flavivirus post-infection and post-vaccination sera Karin Stiasny, Vienna, Austria Experimental infection of horses with nonprimate hepacivirus mediates immune protection against re-infection Stephanie Pfänder, Hannover, Germany Félix A. Rey, Paris, France Kay Grünewald, Hamburg, Germany Keynote: The structurally identified homology between viral and cellular membrane fusion proteins highlights the impact of genetic exchanges during evolution Félix A. Rey, Paris, France Flying viruses – from biophysical to structural characterisation Charlotte Uetrecht, Hamburg, Germany Live cell dynamics of herpesvirus nuclear egress Jens Bosse, Hamburg, Germany Cellular microtubule scaffold promotes efficient assembly and genome packaging of the non-enveloped virus reovirus Pranav Shah, Heidelberg, Germany Aggregates or virus-like particles? Ordered structure of isolated matrix protein M1 revealed by SAXS and AFM Eleonora Shtykova, Moscow, Russian Federation Acidic pH-induced conformation and LAMP1 inding of the lassa virus glycoprotein spike Sai Li, Oxford, UK Nucleic acid binding motif in capsid protein of Mason-Pfizer monkey virus Pavel Ulbrich, Prague, Czech Republic Hans-Jürgen Stellbrink, Hamburg, Germany Jürgen Rockstroh, Bonn, Germany Keynote: Approved antivirals for HIV, HBV and HCV: What has been achieved, what are the remaining challenges? Jürgen Rockstroh, Bonn, Germany Keynote: Presence and future of HEV treatment options Sven Pischke, Hamburg, Germany Acute hepatitis E in patients with gynecological malignancy – a case series Stefan Schlabe, Bonn, Germany In silico evaluation of Oseltamivir treatment strategies against Influenza – Pneumococcus coinfection Alessandro Boianelli, Braunschweig, Germany 15:00 – 15:30 15:00 – 17:00 15:30 – 15:45 15:45 – 16:00 WS9: Humoral Immune Response to Viral Infection 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 Chairpersons 15:00 – 15:30 15:00 – 17:00 15:30 – 15:45 15:45 – 16:00 WS10: Virus Structure and Imaging 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 Chairpersons 15:00 – 15:30 15:00 – 16:30 Thursday, 20th October 16:45 – 17:00 WS11: Approved Antiviral Therapies 15:30 – 16:00 16:00 – 16:15 16:15 – 16:30 Room Hall 1 – 2. Floor Period Hall F – 2. Floor Date * subject to change Hall A – 1. Floor Complete Preliminary Programme (ECV 2016)) 6th European Congress of Virology Session Time Lecture/Event Chairpersons Dana Wolf, Jerusalem, Israel Annette Haberl, Frankfurt, Germany Keynote: Congenital human cytomegalovirus transmission and pathogenesis: From epidemiology to experimental modeling Dana Wolf, Jerusalem, Israel Differential diagnosis of respiratory and enteric viral infections in children Aleksandra Nikonova, Moscow, Russian Federation Discovery of a potent, M2-1-targeting inhibitor of human respiratory syncytial virus infection in vivo Benjamin Bailly, Gold Coast, Australia Repurposing suramin and zanamivir into a synergistic combination that blocks human parainfluenza type-3 virus infection Benjamin Bailly, Gold Coast, Australia Vaccine effectiveness and genetic diversity in the context of increasing immunization rates against Rotavirus infections Corinna Pietsch, Leipzig, Germany Universal neonatal Cytomegalovirus screening using saliva: Report of an experience in an Italian center Andrea Busni, Brescia, Italy Development of a murine model of Enterovirus 71 (EV71) infection, disease, and pathology using mouse-cell-adapted strains Carla B. L. Victorio, Singapore, Singapore 15:00 – 15:30 15:30 – 15:45 WS12: Pediatric Viral Infections 15:00 – 17:00 Thursday, 20th October 15:45 – 16:00 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 17:15 – 18:00 EVA – European Virology Award 17:30 – 19:30 Poster Session – Scientific Networking from 18:30 ESV – Executive Board and Advisory Council Meeting Room Hall B – 1. Floor Period Hall 1 – 2. Floor Date * subject to change Hall C – 1. Floor Complete Preliminary Programme (ECV 2016)) 6th European Congress of Virology Session Time Lecture/Event Chairpersons Ralf Wagner, Regensburg, Germany Giuseppe Pantaleo, Lausanne, Switzerland Keynote: HIV vaccine: Myth or reality? Giuseppe Pantaleo, Lausanne, Switzerland rVSV-platform: Immunogenicity data against the vector and insert of rVSVZEBOV in healthy adults – a phase I study Christine Dahlke, Hamburg, Germany Vaccine generation against gamma herpesvirus infection in a murine surrogate model Baila Samreen, Düsseldorf, Germany Efficient immunization and full protection from lethal challenge by DNA-YFVax, a novel thermostable and readily scalable plasmid-launched live-attenuated yellow fever vaccine candidate produced in E. coli Kai Dallmeier, Leuven, Belgium Triterpen saponins of plant origin incorporated into saponin/lipid nanoparticles as an efficient adjuvant system for mucosal immunization Vladimir Berezin, Almaty, Kazakhstan Modified vaccinia virus based vaccine protection against MERS-CoV infection in dromedary camels V. Stalin Raj, Rotterdam, The Netherlands Pathogens inactivated by low-energy-electron irradiation maintain antigenic properties and induce protective immune responses Jasmin Fertey, Leipzig, Germany Thomas Mettenleiter, Greifswald – Insel Riems, Germany Wim H. van der Poel, Wageningen, The Netherlands Keynote: Emerging topics at issue in veterinary virology Wim H. van der Poel, Wageningen, The Netherlands Full-genome based molecular characterization of encephalitis-associated bovine astroviruses Torsten Seuberlich, Bern, Switzerland Newly discovered polyomaviruses in animals: Uncovering causality Patricia Pesavento, Davis CA, USA Macrophages from pigs lacking the SRCR5 domain of CD163 are resistant to porcine reproductive and respiratory syndrome virus infection Christine Burkard, Roslin, UK Virus-host interactome high-throughput mapping: From the identification of new factors of pathogenicity and interspecies transmission to new therapeutic targets for an animal arbovirus Grégory Caignard, Maisons-Alfort, France Immunogenicity and protective efficacy of recombinant Modified Vaccinia virus Ankara candidate vaccines delivering West Nile virus envelope antigens vaccine Asisa Volz, Munich, Germany Novel variant of porcine epidemic diarrhea virus in England detected through archive mining Falko Steinbach, Addlestone, UK Thomas Dobner, Hamburg, Germany Massimo Tommasino, Lyon, France Keynote: Novel insights into viral-mediated tumorigenesis Susanna Chiocca, Milano, Italy Keynote: Oncogenic viruses and more: Impact on host pathways and cooperation with environmental factors Massimo Tommasino, Lyon, France 08:30 – 09:00 09:00 – 09:15 08:30 – 10:30 09:15 – 09:30 WS13: Antiviral Vaccines 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 Friday, 21st October 10:15 – 10:30 Chairpersons 08:30 – 09:00 09:00 – 09:15 08:30 – 10:30 09:15 – 09:30 09:30 – 09:45 WS14: Emerging Topics in Veterinary Virology 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30 08:30 – 10:30 Chairpersons WS15: Oncogenic Mechanisms of Viruses 08:30 – 09:00 09:00 – 09:30 Room Hall 1 – 2. Floor Period Hall F – 2. Floor Date * subject to change Hall A – 1. Floor Complete Preliminary Programme (ECV 2016)) 6th European Congress of Virology Complete Preliminary Programme (ECV 2016)) Lecture/Event 09:30 – 09:45 Human papillomavirus oncogenes contribute to acquisition of stem cell ability in vitro Katerina Strati, Nicosia, Cyprus PTPN14 is a novel degradation target of human papillomavirus E7 oncoprotein Anita Szalmas, Debrecen, Hungary Interaction of the Merkel Cell polyomavirus LT-antigen with host cell chromatin Juliane Theiss, Hamburg, Germany Establishment of a human adult stem cell model to understand the role of EBV oncogenic mechanisms in epithelial malignancies Wilhelm Ching, Hamburg, Germany Bernhard Fleckenstein, Erlangen, Germany Carmen Rivas, Madrid, Spain Keynote: Targeting of cellular SUMO-regulated pathways by KSHV latent protein LANA2 Carmen Rivas, Madrid, Spain Classical swine fever virus generate superinfection exclusion at the organism level in swine Llilianne Ganges, Barcelona, Spain Parvovirus B19 persists in tonsillar B cells Mari Toppinen, Helsinki, Finland Humanized mice to study acute and persistent human adenovirus infections Estefania Rodriguez, Hamburg, Germany Generation of human peripheral neurons to study Varicella Zoster virus latency, reactivation and induction of pain Abel Viejo-Borbolla, Hannover, Germany Analyzing mechanisms of KSHV latency and intervention using novel in vitro and in vivo models Tatyana Dubich, Braunschweig, Germany BRD2/4-mediated chromatin association of LANA is important for latent persistence of KSHV Rishikesh Lotke, Hannover, Germany Coffee Break Foyer D-G; Hall G, D and E – 2.Floor Marylyn M. Addo, Hamburg, Germany Denis Fargette, Montpellier, France Filovirus infections in bats and humans Jonathan Towner, Atlanta GA, USA Emerging viral infections: The power of deep sequencing Martin Beer, Greifswald - Insel Riems, Germany Biogeography of viral emergence: Rice yellow mottle virus as a case study Denis Fargette, Montpellier, France Emerging viruses in the Balkan and Mediterranean region Anna Papa, Thessaloniki, Greece Lunch Break Foyer D-G; Hall G, D and E – 2.Floor 09:45 – 10:00 WS15: Oncogenic Mechanisms of Viruses 10:00 – 10:15 10:15 – 10:30 Chairpersons 08:30 – 10:30 09:00 – 09:15 09:15 – 09:30 WS16: Viral Latency and Persistence 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30 10:30 – 11:00 Chairpersons 11:00 – 13:00 Friday, 21st October 08:30 – 09:00 11:00 – 11:30 Plenary Session 3: Emerging Virus Infections 11:30 – 12:00 12:00 – 12:30 12:30 – 13:00 13:00 – 15:00 Satellite Symposium 13:15 – 14:45 Room Hall A – 1. Floor Time Hall B – 1. Floor Session Hall 1 – 2. Floor Period ANRS / DZIF Symposium: “HBV and HIV Cure“ Hall F – 2. Floor Date * subject to change 6th European Congress of Virology Session Time Lecture/Event Chairpersons Ben Berkhout, Amsterdam, The Netherlands Ralf Bartenschlager, Heidelberg, Germany Keynote: From oncolytic virotherapy to oncolytic immunotherapy Gabriella Campadelli-Fiume, Bologna, Italy Keynote: Antiviral therapy of chronic hepatitis C: Remaining challenges and new opportunities Ralf Bartenschlager, Heidelberg, Germany Polo-like-kinase 1 is a proviral host-factor for hepatitis B virus replication and a target for combined antiviral strategies David Durantel, Lyon, France Characterization of a novel human monoclonal antibody targeting the hepatitis C virus envelope protein Ahmed Atef Mesalam, Ghent, Belgium Humanization of a claudin-1-specific monoclonal antibody to prevent and cure HCV infection without escape Che C. Colpitts, Strasbourg, France A phase 1, open label, dose-escalation study of the safety, pharmacokinetics and antiretroviral activity of 10-1074 monoclonal antibody in HIV-infected and HIV-uninfected individuals Till Schoofs, New York City NY, USA Stefan Günther, Hamburg, Germany Heinz Feldmann, Hamilton MT, USA Keynote: Vaccine approaches for highly pathogenic viruses Heinz Feldmann, Hamilton MT, USA Interference of MERS-CoV accessory genes with the innate immune response and their contribution to virulence Isabel Sola, Madrid, Spain Role of SARS-CoV viroporins E, 3a, and 8a in virus replication and virulence: Complementation between the PBMs of E and 3a proteins Carlos Castaño-Rodríguez, Madrid, Spain Immune markers of fatal human Ebola virus disease Paula Ruibal, Hamburg, Germany Regulation of Ebola virus matrix protein VP40 by SUMO Maite Baz-Martínez, Santiago de Compostela, Spain Efficacy of Favipiravir and Ribavirin in a novel mouse model of Lassa fever Lisa Oestereich, Hamburg, Germany HPAIV H5 evolution requires adaptation of the hemagglutinin by elevation of the fusion competence activation pH Jürgen Stech, Greifswald – Insel Riems, Germany Wolfram Brune, Hamburg, Germany Bryan R. Cullen, Durham NC, USA Keynote: Post-transcriptional regulation of viral gene expression Bryan R. Cullen, Durham NC, USA A broad RNA virus survey identifies the miR-17 family as a critical host factor for pestiviruses Troels K. H. Scheel, Copenhagen, Denmark An unprecedented protein-stimulated -2/-1 ribosomal frameshift mechanism in arteriviruses Eric Snijder, Leiden, The Netherlands A systematic view on influenza induced host shut-off Julie Tai, Rehovot, Israel Novel preferences in influenza A virus cap-snatching Zuleyma Peralta, New York City NY, USA Spatiotemporal analysis of global protein synthesis and PML domains association during HSV infection revealed by click chemistry Su Hui Catherine Teo, London, UK Cardiotonic steroids suppress adenovirus replication Martha Brown, Toronto, Canada 15:00 – 15:30 15:00 – 17:00 15:30 – 16:00 16:00 – 16:15 WS17: Experimental Antiviral Therapies 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 Chairpersons 15:00 – 17:00 15:30 – 15:45 15:45 – 16:00 WS18: Highly Pathogenic Viruses 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 Chairpersons 15:00 – 15:30 15:30 – 15:45 15:00 – 17:00 Friday, 21st October 15:00 – 15:30 WS19: Viral Gene Expression – Transcription, Translation 15:45 – 16:00 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 Room Hall 1 – 2. Floor Period Hall F – 2. Floor Date * subject to change Hall A – 1. Floor Complete Preliminary Programme (ECV 2016)) 6th European Congress of Virology Session Time Lecture/Event Chairpersons Gerd Sutter, Munich, Germany Peter Liljeström, Stockholm, Sweden Keynote: RNA replicon vaccines Peter Liljeström, Stockholm, Sweden Development of MVA-MERS-S for phase I clinical evaluation: A candidate vaccine against Middle East Respiratory Syndrome coronavirus Asisa Volz, Munich, Germany Clonal Oka varicella vaccine variants with reduced viral genome size and presumed higher clinical safety Husam Taher, Kiel, Germany Development of an artificial reassortant of Infectious Salmon Anaemia Virus (ISAV) with reverse genetic system: The solution for a new vaccine against uncultivable HPR0 genotype strains Marcelo Cortez-San Martín, Santiago de Chile, Chile The viral vector vaccine VSV-GP as vaccine platform C. Anika Bresk, Innsbruck, Austria Priming with a potent HIV-1 DNA vaccine frames the quality of T cell and antibody responses prior to a poxvirus and protein boost Benedikt Asbach, Regensburg, Germany Integrative approaches towards the generation of a synthetic polio vaccine Mohammad W. Bahar, Oxford, UK 15:00 – 15:30 15:00 – 17:00 Friday, 21st October 15:30 – 15:45 15:45 – 16:00 WS20: Viral Vectors for Vaccine Design 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 17:15 – 19:00 General Assembly – ESV 17:15 – 19:00 Poster Session – Scientific Networking 19:00 – 00:00 Congress Dinner & Networking Event Room Hall B - 1. Floor Period Hall 1 – 2. Floor Date * subject to change Hall 3 – Ground Floor Complete Preliminary Programme (ECV 2016)) 6th European Congress of Virology Session Time Lecture/Event Chairpersons Todd Allen, Cambridge MA, USA Rolf Kaiser, Cologne, Germany Keynote: HIV resistance testing from 1999 to 2016 and beyond Rolf Kaiser, Cologne, Germany Characterisation of longitudinal human cytomegalovirus genome diversity by next generation sequencing of blood samples from immunocompromised patients suggests turnover of viral strains Elias Hage, Hannover, Germany PatchDetection: Inference of (seasonally) reoccurring patterns of patches under positive selection in human influenza A/H3N2 viruses Thorsten R. Klingen, Braunschweig, Germany Differences among mumps virus surface proteins between genotype G and other genotypes at sites important for immunity and pathogenesis Tessa Vermeire, Ukkel, Belgium Use of Ebola pseudoviruses to interrogate the impact of Ebolavirus glycoprotein evolution during the West African outbreak Richard A. Urbanowicz, Nottingham, UK Fitness changes and mutation dynamics in evolved hepatitis C virus populations in the cell culture system Elena Moreno del Olmo, Madrid, Spain Ribavirin-induced mutagenesis of the hepatitis E virus genome in vivo Daniel Todt, Hannover, Germany Marion Koopmans, Rotterdam, The Netherlands Christian Drosten, Bonn, Germany Keynote: MERS – a classical zoonosis with a pre-pandemic implication Christian Drosten, Bonn, Germany 08:30 – 09:00 08:30 – 10:30 09:00 – 09:15 09:15 – 09:30 WS21: Viral Evolution and Resistance 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 Chairpersons 08:30 – 09:00 09:00 – 09:15 08:30 – 10:30 09:15 – 09:30 WS22: Virus Epidemiology and Surveillance 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30 Chairpersons 08:30 – 09:00 08:30 – 10:30 Saturday, 22nd October 10:15 – 10:30 WS23: Infection of the Immunocompromised 09:00 – 09:15 09:15 – 09:30 09:30 – 09:45 Seasonality and selective trends in viral acute respiratory tract infections Patrick Shaw Stewart, Hungerford, UK Emergence of highly pathogenic H5Nx influenza A viruses is accompanied with a change in H5 receptor-binding specificity Erik de Vries, Utrecht, The Netherlands Ebola virus disease: Epidemiological modelling and impacts of vaccination and other measures to improve survival Che Ismail Che Noh, Kota Kinabalu, Malaysia MERS update in Saudi Arabia and probable future outbreaks Islam Nour, Riyadh, Saudi Arabia Epidemiology of the four human coronavirus 229E, HKU1, NL63, and OC43 detected over two years in hospitalized adult patients Giuseppe Paganini, Brescia, Italy Targeted enrichment of viral DNA in soft tissues from 300-year-old mummies from Lithuania Klaus Hedman, Helsinki, Finland Thomas Schulz, Hannover, Germany Hans Hirsch, Basel, Switzerland Keynote: Immune responses in replicative and non-replicative virus pathology: What we can we learn from polyomaviruses Hans Hirsch, Basel, Switzerland The challenges of data robustness in sequencing complete human cytomegalovirus genomes directly from clinical material Nicolas Suarez, Glasgow, UK Are human myeloid dendritic cells hijacked by the BK polyomavirus? Mathieu Sikorski, Nantes, France Role of neutralizing antibodies in the control of BK polyomavirus reactivation in kidney transplant recipients Dorian Mcilroy, Nantes, France Room Hall 1 – 2. Floor Period Hall F – 2. Floor Date * subject to change Hall A – 1. Floor Complete Preliminary Programme (ECV 2016)) 6th European Congress of Virology Complete Preliminary Programme (ECV 2016)) Lecture/Event 09:45 – 10:00 Survival and immunological improvement of ART-naïve HIV patients by HPgV coinfection Gibran Horemheb-Rubio, Mexico City, Mexico Immune reconstitution hepatitis A in a patient with AIDS demonstrates the importance of immunopathology Thomas Harrer, Erlangen, Germany Hepatitis E at a tertiary center in Northern Germany Dirk Westhölter, Hamburg, Germany Gülsah Gabriel, Hamburg, Germany Noël Tordo, Paris, France Keynote: Ebola and Rabies, bats and dogs: Differences and similarities between two zoonoses, applicability of the “One Health“ concept Noël Tordo, Paris, France The sialic acid binding preference determines the differential interaction between influenza A viruses and streptococci Jie Tong, Hannover, Germany The neuraminidase protein of novel H7N9 virus displays reduced enzymatic activity resulting from mutation of the 2nd sialic acid binding site Meiling Dai, Utrecht, The Netherlands Host-symbionts interaction driving evolution of alpha and beta coronaviruses (CoVs) in their bat hosts Stefania Leopardi, Legnaro, Italy Bat coronaviruses in France and Western Palearctic: After MERS-CoV and SARS-CoV, are there other candidates to emergence? Meriadeg Ar Gouilh, Paris, France Stem cell-derived hepatocellular systems for the study of genuine pangenotype hepatitis E virus replication Viet Loan Dao Thi, New York City NY, USA PTLV-1 among humans in two regions of tropical Africa Grit Schubert, Berlin, Germany Coffee Break Foyer D-G; Hall G, D and E – 2.Floor 10:00 – 10:15 10:15 – 10:30 Chairpersons 08:30 – 09:00 08:30 – 10:30 09:00 – 09:15 09:15 – 09:30 WS24: Zoonotic Viruses 09:30 – 09:45 Saturday, 22nd October 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30 10:30 – 11:00 Chairpersons 11:00 – 13:00 11:00 – 11:30 Plenary Session 4: Next Generation Viromics 11:30 – 12:00 12:00 – 12:30 12:30 – 13:00 Adam Grundhoff, Hamburg, Germany Albert Osterhaus, Hannover, Germany Virus genome variation in infected individuals and populations Paul Kellam, Cambridge, UK The merging of fields through NGS applications in emerging infectious diseases Marion Koopmans, Rotterdam, The Netherlands Viral signatures of immune control of HIV and HCV Todd Allen, Cambridge MA, USA Virus discovery in human and animals: From genomes to diseases Eric Delwart, San Francisco CA, USA Lunch Break Foyer D-G; Hall G, D and E – 2.Floor Satellite Symposium 13:15 – 14:45 Erasmus MC / Institut Pasteur Symposium: “Emerging Zoonoses“ Satellite Symposium 13:15 – 14:45 ESV – Symposium: “Challenges in Clinical Virology” Hall F – 2. Floor Ulrike C. Lange, Hamburg, Germany Thomas F. Baumert, Strasbourg, France Keynote: Cell circuits of viral entry, disease biology and antiviral therapy Thomas F. Baumert, Strasbourg, France Keynote: Genome editing as antiviral therapy Frank Buchholz, Dresden, Germany Hall 1 – 2. Floor 15:00 – 17:00 13:00 – 15:00 Room Hall A – 1. Floor WS23: Infection of the Immunocompromised Time Hall B – 1. Floor Session Hall 1 – 2. Floor Period Hall A – 1. Floor Date * subject to change Chairpersons WS25: Curative Strategies for Virus Eradication 15:00 – 15:30 15:30 – 16:00 6th European Congress of Virology Lecture/Event 16:00 – 16:15 Novel targets for potent antiviral drugs: The development of Pritelivir and Letermovir against viruses from the herpes group Helga Rübsamen-Schaeff, Frankfurt, Germany Antiviral effects of zinc oxide (ZnO) nanoparticles against H1N1 (pdm09) Rishikesh Kumar, Patna, India Natural humic substances interfere with multiple stages of the replication cycle of human immunodeficiency virus Yury Zhernov, Moscow, Russian Federation Antiviral activity of apigenin against African swine fever virus Hovakim Zakaryan, Yerevan, Armenia Nicole Fischer, Hamburg, Germany Eric Delwart, San Francisco CA, USA Keynote: Animal viruses leaving the animal-human interface Albert Osterhaus, Hannover, Germany Polymycoviridae: An emerging family of mycoviruses Ioly Kotta-Loizou, London, UK Discovery and characterization of a new avian hepatitis B virus in a palaeognath bird Wendy K. Jo, Hannover, Germany Co-circulation of potentially novel paramyxoviruses in bats in Central Brazi William Marciel Souza, Ribeirão Preto, Brazil Investigation of hantavirus prevalence in wild rodent population in the United Kingdom Joe Chappell, Nottingham, UK Sero- and genoepidemiology of two human protoparvoviruses, bufavirus and tusavirus Elina Väisänen, Helsinki, Finland HERV-W group evolutionary history: Characterization of the group in nonhuman primates and identification of highly related sequences in new world monkeys Nicole Grandi, Cagliari, Italy Daniel Cadar, Hamburg, Germany Stéphane Blanc, Montpellier, France Keynote: Vector transmission: Commonalities and specificities in plant and animal viruses Stéphane Blanc, Montpellier, France Keynote: Zika virus pathogenesis Helen Lazear, Chapel Hill NC, USA Mosquito-specifc bunyaviruses Ingeborg van Knippenberg, Glasgow, UK Mosquito saliva increases endothelial permeability in the skin, immune cell migration and dengue pathogenesis during antibody-dependent enhancement Michael A. Schmid, Berkeley CA, USA Alpha-repeat molecules as novel antivirals against flaviviruses by targeting the envelope glycoprotein and the NS1 protein Wilhelm Furnon, Lyon, France Antiviral piRNA pathway in the arbovirus vector Aedes aegypti Margus Varjak, Glasgow, UK Julian Schulze zur Wiesch, Hamburg, Germany Karin Mölling, Berlin, Germany Short presentations selected from Poster Sessions 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 Chairpersons 15:00 – 15:30 15:30 – 15:45 15:00 – 17:00 WS26: Virus Discovery, Typing and Metagenomics 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 Chairpersons 15:00 – 17:00 15:00 – 15:30 15:30 – 16:00 WS27: Vector Borne Infections 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 15:00 – 17:00 Saturday, 22nd October 15:45 – 16:00 WS28: Best of Posters Chairpersons 15:00 – 17:00 17:15 – 18:00 Life Science Nord – Poster Prize Farewell – Next Meeting Presentation Room Hall 1 – 2. Floor WS25: Curative Strategies for Virus Eradication Time Hall F – 2. Floor Session Hall A – 1. Floor Period Hall B – 1. Floor Date * subject to change Hall 1 – 2.Floor Complete Preliminary Programme (ECV 2016))