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Direct and indirect motor pathways to the spinal cord. In the lateral view of the human brain; numbered areas are functional areas identified by Brodmann. The transverse section of the spinal cord shows three functional areas. The dorsal horn contains the sensory neurons of the spinal cord; the intermediate zone contains interneurons; and the motor nuclei zone contains the motor neurons that innervate the muscles. A. The corticospinal tract, also called the pyramidal tract, originates in a vast region around the central sulcus that includes the parietal lobe and the posterior part of the frontal lobe (areas 4 and 6). Area 4, the primary motor cortex, is the only area of motor cortex that directly connects with spinal motor neurons. Area 6 comprises various subareas, most of which send fibers to interneurons the intermediate zone of the spinal cord. The parietal lobe sends Source: Cognitive Functions of the Premotor Systems, Principles of Neural in Science, Fifth Editon fibers to the dorsal horns. Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available B. Indirect pathways to spinal motor neurons originate in 10, area2017 4 and area 6 and terminate in medial and lateral areas of the brain stem. The main at: http://mhmedical.com/ Accessed: May components Copyright of the medial pathways are the reticulospinal, medial and lateral vestibulospinal, and tectospinal tracts; they descend in the ventral column © 2017 McGraw-Hill Education. All rights reserved and terminate in the ventromedial area of the spinal gray matter. The main lateral pathway is the rubrospinal tract, which originates in the magnocellular