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Faustino R. Pérez-López ENDOMETRIAL AND OTHER CANCERS IN THE MENOPAUSE Learning Objectives Recognize the current evidence-based recommendations for women in their second half of life regarding genital cancer risk and diagnosis Describe current general approaches for the management of genital cancer Cancer and menopause Menopause is not associated with increased cancer risk However, cancer rates increase with age and cancer is the second leading cause of death in women Special attention should be provided about oncologic issues during the second half of life Genetic factors and cancer Genetics may contribute to the risk of various cancers Mass screening for specific mutations cannot be used in the general population There are no clear screening tests for some cancers (endometrial, ovarian, vulvar, lung) Preventive measures are based upon early organ extirpation in genetic mutation carriers Lifestyle and cancer: modifiable risk factors Smoking Alcohol High body mass index Dietary factors Physical activity Use of hormones Infertility treatments Hormone contraception Menopause hormone therapy Outline 1. Endometrial cancer 2. Uterine sarcoma 3. Ovarian cancer 4. Cervix cancer 5. Vulvar cancer 6. Other cancers