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Human Anatomy OVERVIEW OF THE BASIC ACTIVITIES OF LIFE A living organism is in homeostasis if all of its organ systems work together as a single unit to regulate the basic activities of life. They include: 1) Respiration We need energy to grow, to maintain homeostasis, to defend ourselves from foreign molecules, to repair cells and to reproduce. The cells undergo cellular respiration, aeorobic respiration (oxygen is needed). Respiration refers to the intake of oxygen in the lungs and the oxidation of molecules such as carbohydrates, lipids and proteins to make energy. Source(figure):http://ejels.blackgold.ca/projects/Grade_8/Tael ar/Body_Systems_Website/respiratory-system.jpg External respiration is the ventilation of air into the lungs, and the gas exchange between the alveoli and the blood capillaries. Blood exchanges carbon dioxide for oxygen from the lungs. Carbon dioxide is exhaled out. Internal respiration is the gas exchange between the blood and the tissues. Tissues exchange the carbon dioxide for the oxygen. The de-oxygenated blood (blood with carbon dioxide) will go back to the lungs to get oxygenated, and the cycle will repeat again. 2) Nutrient Transport The cardiovascular system consists of the heart, blood vessels and blood. Deoxygenated blood comes to the right side of heart to be pumped up into the lungs to get oxygenated. Then the oxygenated blood goes to the left side of the heart to be pumped out from the aorta to the tissues where they exchange wastes and carbon dioxide Source(figure):http://www.urgomedical.com/var/ezflow_site/st orage/images/media/images/venous-system-02/2059-1-engGB/venous-system-02.jpg with oxygen and nutrients by diffusion. The capillaries containing deoxygenated blood go back to the heart and the cycle repeats. 3) Digestion Humans are heterotrophs as they do not have mechanisms to make their own nutrients. Without nutrients, our system would shut down because it would lack the energy for growth, repair and overall functioning. We ingest food to obtain energy and nutrition. Digestion of food is the breakdown of molecules into smaller ones that can be absorbed into the blood, which will transport them to the cells as needed. Macromolecules include carbohydrates, proteins, lipids and nucleic acids. Carbohydrates have monosaccharides as their smallest unit, proteins have amino acids, lipids have glycerol and fatty acids, whereas nucleic acids have nucleotides. The digestive tract of humans starts with the oral cavity, then pharynx, followed by esophagus, the stomach, the small intestine, the large intestine and the anus. The breakdown of carbohydrates starts in the oral cavity. The food moves down the esophagus (peristalsis) by involuntary contractions. The stomach Source(figure):http://upload.wikimedia.org/wikipedia/common secretes acidic juice and s/thumb/c/c5/Digestive_system_diagram_edit.svg/340pxproteinases (enzymes that break Digestive_system_diagram_edit.svg.png down proteins) to kill bacteria and break down proteins into amino acids. The liver and the pancreas assist the small intestine by secreting bile and pancreatic juice to break down lipids, more proteins and carbohydrates. Amino acids, monosaccharides and fatty acids are then allowed to be absorbed into the bloodstream. The longer the small intestine, the greater the digestion and absorption. The large intestines allow for the absorption of any water or salts left over. Rectum stores feces before elimination through the anus. 5) Excretion Excretion refers to the removal of metabolic wastes produced in the body. The main organs of excretion are skin, lungs, liver and most importantly kidneys. Sweat glands in the skin excrete water (with dissolved salts). We exhale carbon dioxide from the lungs where the gas exchange happened between alveoli and capillaries. The liver is responsible for the breakdown of amino acids, a process that releases ammonia, which is converted into urea to decrease its toxicity. Urea diffuses into the blood and is finally secreted from the kidneys. Kidneys are responsible for filtering the blood, processing the filtrate into urine and releasing urine into the ureters. The bladder stores the urine before excretion through the urethra. *** NOTE: Elimination (following digestion) rids us of undigested material. Excretion is the removal of metabolic products. 6) Movement The musculoskeletal system provides the framework for the human body. Muscles are attached to the bones to allow locomotion. Our skeletal system provides physical support, organ protection, and movement. Our skeleton is made out of cartilage (flexible connective tissue) and bone (enduring connective tissue). Our muscular system generates force. There are three types of muscle: skeletal (used for voluntary movements), smooth (surrounds the organs, mostly), and cardiac (makes up the muscle tissue of the heart). 7) Nervous System The nervous system allows us to receive and respond to a stimulus from the external and internal environment. The functional unit of the nervous system is the neuron, which is responsible for nerve conduction. Neuroglia makes up the team of cells that provides nutrition and support for the neurons. The nervous system has two divisions: the peripheral and the central nervous system. The central nervous system consists of the brain and the spinal cord. The peripheral nervous system consists of the efferent neurons (to the brain) and afferent neurons (away from the brain). 8) Endocrine System It is used to coordinate the activities of organ systems, internally. Endocrine glands make and secrete hormones directly into the bloodstream as needed. Some of them are: • • • • • • • pituitary gland which releases ADH to increase the water absorption in the blood from the nephron thyroid gland produces calcitonin hormone to decrease blood calcium level parathyroid gland produces PTH to increase blood calcium levels by stimulating calcium absorption from the digestive tract adrenal cortex produces aldosterone to promote sodium and water absorption into the blood pancreas produces glycagon to increase blood glucose level, and insulin to lower blood glucose level heart produces ANP to prevent the release of aldosterone from the adrenal cortex thus allowing the excretion of sodium and water with urine. kidneys make renin – enzyme that eventually leads to the stimulation of adrenal cortex to produce aldosterone. They also make erythropotein – glycoprotein that promotes red blood cell production ***NOTE: Endocrine system responds slower than the nervous system.