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Mitosis Vocabulary Quiz Name: __________________________________ 1. ___________________________The reproduction of cells. 2. ___________________________In a duplicated chromosome, the region on each sister chromatid where it is most closely attached to the other chromatid by proteins that bind to the centromeric DNS. Other proteins condense the chromatin in that region, so it appears as a narrow ‘’waist” on the duplicated chromosome. 3. ___________________________A structure present in the cytoplasm of animal cells that functions as a microtubule-organizing center and is important during cell division. A centrosome has two centrioles. 4. ___________________________An ordered sequence of events in the life of a cell, from its origin in the division of a parent cell until its own division into two. The eukaryotic cell cycle is composed of interphase, and M phase. 5. ___________________________A Cellular structure consisting of one DNA molecule and associated protein molecules. 6. ___________________________The process of cytokinesis in animal cells, characterized by pinching of the plasma membrane. The succession of rapid cell divisions without significant growth during early embryonic development that converts the zygote to a ball of cells. 7. ___________________________The first sign of cleavage in an animal cell; a shallow groove around the cell in the cell surface near the old metaphase plate. 8. ___________________________A membrane-bounded flattened sac located in the middle of a dividing plant cell inside which the new cell wall forms during cytokinesis 9. ___________________________A cellular protein that occurs in a cyclically fluctuating concentration and that plays an important role in regulating the cell cycle. 10. ___________________________A haploid reproductive cell, such as an egg or a sperm. Gametes unite during sexual reproduction to produce a diploid zygote. 11. ___________________________The genetic material of an organism or virus; the complete complement of an organism’s or virus’s genes along with its noncoding nucleic acid sequence. 12. ___________________________A protein that must be present in the extracellular environment for the growth and normal development of certain types of cells. 13. ___________________________A process of nuclear division in Eukaryotic cells conventionally divided into 5 stages. Conserves chromosome number by allocating replicated chromosomes equally to each of the daughter nuclei. 14. ___________________________The phase of the cell cycle that include mitosis and cytokinesis. 15. An assemblage of microtubules and associated proteins that is involved in the movement of chromosomes during mitosis. 16. ___________________________A nondividing state occupied by cells that have left the cell cycle, sometimes reversibly. 17. ___________________________The first gap, or growth phase, of the cell cycle consisting of the portion of interphase before DNA Synthesis begins. 18. ___________________________The second gap, or growth phase, of the cell cycle, consisting of the portion of interphase after DNA synthesis occurs. 19. ___________________________A radial array of short microtubules that extends from each centrosome toward the plasma membrane in an animal cell undergoing mitosis. Mitosis Vocabulary Quiz Name: __________________________________ 20. ___________________________A cyclically operating set of molecules in the eukaryotic cell that both triggers and coordinates key events in the cell cycle. 21. ___________________________The fourth stage of mitosis, in which the chromatids of each chromosome have separated and the daughter chromosomes are moving to the poles of the cell. 22. ___________________________The third stage of mitosis, in which the spindle is complete and the chromosomes attached to microtubules at their kinetochores, are all aligned at the metaphase plate. 23. ___________________________An imaginary structure located at the plane midway between the two poles of a cell in metaphase in which the centromeres of all the duplicated chromosomes are located. 24. ___________________________The first stage of mitosis, in which the chromatin condenses into discrete chromosomes visible with a light microscope, the mitotic spindle begins to form, and the nucleolus disappears but the nucleus remains intact. 25. ___________________________The second stage of mitosis, in which the nuclear envelope fragments and the spindle microtubules attach to the kinetochores of the chromosomes. 26. ___________________________The synthesis phase of the cell cycle; the portion of interphase during which DNA is replicated. 27. ___________________________Two copies of a duplicated chromosome attached to each other by proteins at the centromere and, sometimes, along the arms. While joined, two sister chromatids make up one chromosome. Chromatids are eventually separated during mitosis or meiosis II. 28. ___________________________Any cell in a multicellular organism except a sperm or egg or their precursors. 29. ___________________________Site where the replication of a DNA molecule begins, consisting of a specific sequence of nucleotides. 30. ___________________________The fifth and final stage of mitosis, in which daughter nuclei are forming and cytokinesis has typically begun. 31. ___________________________The spread of cancer cells to locations distant from their original site. 32. ___________________________A mass of abnormal cells with specific genetic and cellular changes such that the cells are not capable of surviving at a new site and generally remain at the site of the tumor’s origins. 33. ___________________________A cancerous tumor containing cells that have significant genetic and cellular changes and are capable of invading and surviving in new sites. Can impair functions of one or more organs. 34. ___________________________A method of asexual reproduction by “division in half”. In prokaryotes, binary fission does not involve mitosis, but in single celled eukaryotes that undergo binary fission, mitosis is part of the process. 35. ___________________________The phenomenon observed in normal animal cells that causes them to stop dividing when they come into contact with one another. Mitosis Vocabulary Quiz Name: __________________________________ 36. ___________________________The requirement that a cell must be attached to a substratum in order to initiate cell division. 37. ___________________________The conversion of a normal cell into a cell that is able to divide indefinitely in culture, thus behaving like a cancer cell. 38. ___________________________A structure of proteins attached to the centromere that links each sister chromatid to the mitotic spindle. 39. ___________________________The division of the cytoplasm to form two separate daughter cells immediately after mitosis, meiosis I, or meiosis II. 40. ___________________________The period in the cell cycle when the cell is not dividing. During interphase, cellular metabolic activity is high, chromosomes and organelles are duplicated, and cell size may increase. Often accounts for up to 90% of the cell cycle. Word Bank Cell Division Cell Cycle Genome Somatic Cells Gametes Sister Chromatids Mitotic Phase Interphase G1 Phase G2 Phase Metaphase Anaphase Telophase Mitotic Spindle Aster Kinetochore Cell Plate Binary Fission Metaphase Plate Origin of Replication Cyclin-dependent Kinases G0 Phase Anchorage Dependent Transformation Metastasis Chromosome Chromatin Mitosis Cytokinesis S Phase Prophase Centrosome Cleavage Cleavage Furrow Cell Cycle Control System Growth Factor Benign tumor Cyclin Density Dependent Inhibition Malignant Tumor