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Circulatory system Premedical Endothermic way of life require 10x more energy (exothermic). Cells of body require nutrients, oxygen and exclude carbon dioxide and wastes. Cardiovascular system: • Blood - blood cells and plasma • Vessels – arteries, veins, capillaries, arterioles, venules, capillary bed • Heart – atria and ventricles Blood pressure Double circulation : independent body and lung circulatory system supported by 4 chambered heart of mammals double circulatory system lymphatic system Lungs the right side of the the left side of the system system deals with deals with deoxygenated oxygenated blood. blood. Body cells The Heart This is a vein. It brings blood from the body, except the lungs. These are arteries. They carry blood away from the heart. 2 atria 2 ventricles Coronary arteries supply the heart with blood first branches The heart has four chambers The Heart artery to lungs vein from head and body right atrium valve right ventricle artery to head and body vein from lungs left atrium valve left ventricle How does the heart work? Heartbeat: STEP ONE blood from the body blood from the lungs The heart beat begins when the heart muscles relax and blood flows into the atria. How does the heart work? STEP TWO The atria then contract and the valves open to allow blood into the ventricles. How does the heart work? STEP THREE The valves close to stop blood flowing backwards. The ventricles contract forcing the blood to leave the heart. At the same time, the atria are relaxing and once again filling with blood. The heartbeat – the cycle repeats itself. Systole is a phase where the myocardium is contracting in a coordinated manner in response to an endogenous electrical stimulus Diastole is the period of time when the heart fills with blood after systole. Cardiac output is the volume of blood being pumped by the heart, in the time interval of one minute Puls - frequency of contractions, normal 70 - 75 / minute Heartbeat - valves close, impact of blood to valves Heart murmur – defect of valve Four valves prevent a backward blood flowing. The AV valve on the right side of the heart is called the tricuspid valve because it has three leaflets (cusps). The AV valve on the left side of the heart is called the bicuspid valve (or mitral valve) because it has two leaflets. Semiluminar: the pulmonary valve the aortic valve Mechanism of heartbeat continuity: Special cardiomyocytes cells with the ability to generate the electrical impulses. They have internal rhythm of contractions. Pacemaker – Sinoatrial node – right atrium Atrioventricular bundle - right side EKG Blood pressure – hydrostatic pressure is a force exerted by circulating blood on the walls of blood vessels. During each heartbeat, BP varies between a maximum (systolic) and a minimum (diastolic) pressure. Thoracic cavity between the lungs and is contained in the pericardial sac • Epicardium – outer layer of heart wall • Endocardium – inner layer that consists of endothelial cells, which line the heart, covers the heart valves, and lines the blood vessels. • Myocardium – middle layer composed of cardiac muscle. There are 3 types of blood vessels a. ARTERY b. VEIN c. CAPILLARY The ARTERY elastic fibres allow the artery to maintain a blood pressure thick muscle with elastic fibres the thick muscle can contract to push the blood along. The VEIN Veins have valves, which prevent a backward blood flow thin muscle and elastic fibres Body muscles surround the veins so that when they contract to move the body, they also squeeze the veins and push the blood along the vessels. The CAPILLARY Basement membrane and endothel the wall of a capillary is only one cell thick The exchange of materials between the blood and the body can only occur through capillaries. The CAPILLARY A collection of capillaries is known as a capillary bed. artery vein capillaries body cell The semi-permeable membrane (basement membrane) of capillary walls allows nutrients, oxygen, and water to diffuse from the blood to the tissues. Waste products, like carbon dioxide, diffuse from the tissues into the blood. Subclavian vein Superior vena cava Pulmonary artery Inferior vena cava Renal vein Iliac vein Femoral vein Carotid arteries Subclavian artery The aorta is Pulmonary vein the largest Aorta artery in the body https://www.pinterest.com/pin/79024168433518856/ Renal artery Iliac artery Femoral artery This portion of the systemic circulation is known as the hepatic portal system. The gastric vein (stomach), splenic vein (spleen), pancreatic vein (pancreas), and mesenteric veins (small intestines) empty into the portal vein that carries the blood to the liver. The hepatic vein carries blood to the inferior (caudal) vena cava. The lymphatic system is part of the immune system and acts as a secondary (accessory) circulatory system. • return water and proteins to blood • remove excess fluids from body tissues, • absorb fatty acid and transport fat to circulatory system, and • produce immune cells (lymphocytes, monocytes, and plasma cells). Flow of Blood & Lymph Within Tissue As the collecting lymph vessel accumulates lymph from more and more lymph capillaries in its course, it becomes larger and is called the afferent lymph vessel as it enters a lymph node. Here the lymph percolates through the lymph node tissue and is removed by the efferent lymph vessel. An efferent lymph vessel may directly drain into one of the (right or thoracic) lymph ducts Both the lymph ducts return the lymph to the blood stream by emptying into the subclavian veins Lymph node Lymph nodes filter foreign substances, such as bacteria and cancer cells, before it is re-entered into the blood system through the larger veins. Lymph nodes act as the body’s first defense against infection. Lymph node has a fibrous outer covering (capsule), a cortex, and a medulla Lymphoid tissue: spleen, thymus, bone marrow and the lymphoid tissue associated with the digestive system. Thank you for your attention Campbell, Neil A., Reece, Jane B., Cain Michael L., Jackson, Robert B., Minorsky, Peter V., Biology, Benjamin-Cummings Publishing Company, 1996 – 2010. chapter 42 www.worldofteaching.com