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Fred Pescatore, MD A L T E R N AT I V E S Curing Sudden Dementia: 1 Swift Action that can Reverse the “Instant Memory Eraser” By Fred Pescatore, M.D. TABLE OF CONTENTS CHAPTER 1 Why undiagnosed cases of sudden dementia are spreading like wildfire............................................................................... 1 CHAPTER 2 How do prescription drugs cause sudden dementia? The truth will shock you................................................................................. 3 CHAPTER 3 The one action that can REVERSE sudden dementia ................................... 5 CHAPTER 4 Do this before your next doctor’s appointment ........................................... 8 CHAPTER 5 Heal your memory naturally........................................................................ 10 Reverse brain shrinkage with this pennies-per-day vitamin cure............... 10 A bigger brain and a better memory with fish oil........................................11 Squash “senior moments” in as little as 1 HOUR...................................... 12 Tack decades onto your brain’s lifespan with vitamin D............................ 15 Stave off dementia with vitamin E............................................................... 16 15 minutes could save your brain.................................................................17 Curing Sudden Dementia Curing Sudden Dementia: 1 Swift Action that can Reverse the “Instant Memory Eraser” CHAPTER 1: WHY UNDIAGNOSED CASES OF SUDDEN DEMENTIA ARE SPREADING LIKE WILDFIRE One crisp but ordinary February morning, Mary Donahue* walked into the kitchen of her rural Indiana home…and felt her blood run cold. She stood frozen to the spot, watching her husband Charles frantically set up row after row of tea cups across the table. Mary asked him what in the world he was doing, but he just kept tearing the wrappers off one tea bag after another…until finally, he’d made 40 cups of tea. “They’re coming,” he shouted. “They’re already here…” And he pointed to the wall. Mary was terrified. Without any warning, her husband’s mind was gone. He was hallucinating, confused…and he was only 57 years old. It was as though dementia had set in OVERNIGHT His wife and his doctors were baffled…how could this happen so suddenly? Details of the case, published in the British Medical Journal, tells us it would be more than a year before doctors finally uncovered the cause of Charles’ sudden dementia… prescription drugs needs to know: It’s not just one specific drug that can cause this kind of memory loss… Every single prescription drug you take puts you at risk for sudden dementia The Memory and Aging Center at the University of California San Francisco reports that a single dose of ANY prescription drug could be enough to trigger this terrifying type of dementia. That’s right. Every single time you add any prescription drug to your regimen, your risk of experiencing memory loss or confusion goes up exponentially. That’s why the phenomenon of sudden dementia is known to researchers as druginduced dementia. Over the last 10 years, prescription drug use has skyrocketed in America. Today, 6 out of every 10 American adults are taking at least one prescription drug. As a result the number of cases of sudden dementia is believed to be on the rise. The question is…how many doctors will be able to pinpoint when drugs are causing severe memory loss? How many will mistake it as “typical” dementia or Alzheimer’s disease? And what about mild memory loss that builds over time? Within 72 hours of stopping the drug, his bizarre behavior…memory loss…and confusion were completely GONE. It’s shocking to think of how many people out there might be going through a situation just as devastating as what happened to Mary and Charles Donahue—and how many may never receive the correct diagnosis. But here’s what every American taking any It’s heartbreaking, because in many cases… It was a prescription drug he’d been taking. 1 Sudden dementia is completely REVERSIBLE …if you know what to do and you act quickly. In many cases, all it takes is getting off the prescription drug (or drugs, plural) that is causing your memory loss. You could even be “back to normal” in as little as 24 hours of having the drug out of your system. prescribed drugs in the U.S. Clinical data published in the British Medical Journal shows this “treatment” can increase your risk of stroke by 36%...your risk of death by 62%...seizures by 119%...and your risk of attempting suicide by a shocking 420%. So if it’s that simple, why aren’t more doctors aware of this? That’s why it’s so important to educate yourself—so you and your loved ones know what to do if sudden dementia strikes your household. Good question. Doctors just don’t realize prescription drugs can cause dementia-like symptoms. They are quick to blame aging, anxiety, depression, dehydration or “typical” dementia…and prescribe another drug to “treat side effects.” Let me show you… And you know what that means: Adding more drugs can make your symptoms worse! Especially if that drug happens to be an antidepressant…one of the most commonly 2 Curing Sudden Dementia You see, there are several ways prescription drugs can cause memory loss, confusion, and dramatic behavioral changes…and you have to find out which one it is to give yourself the best chance of recovery. *Names have been changed to protect privacy. CHAPTER 2: HOW DO PRESCRIPTION DRUGS CAUSE SUDDEN DEMENTIA? The truth will shock you So many people take one or more prescription drugs every day, never knowing the full scope of the risks. Here are the top three ways these drugs can cause dementia symptoms: 1. Nutrient deficiency. Did you know there are at least 52 prescription drugs that can drain an important brain vitamin right out of your body? I’m talking about B12, and not having enough of it is a BIG problem. B12 is critical for clear thinking and a strong memory. In fact, as you’ll see in Chapter 5, vitamin B12 is actually being studied by researchers at UCLA as a cure for dementia and Alzheimer’s disease. The list of drugs that can steal it away includes antiinflammatories, anti-convulsants, ulcer medicines, some common antibiotics…and even the most widely used drug for type II diabetes. Adding insult to injury, prescription drugs can also deplete a host of other nutrients, such as vitamin K, calcium, magnesium…and of course, vitamin D. That’s more bad news for your brain, because having low levels of vitamin D doubles your risk of dementia, according to a recent study published in the journal Neurology. It’s incredible to think something as simple as vitamin B12 could REVERSE symptoms of memory loss and confusion that go hand in hand with sudden dementia… But it’s true. It really can be that easy! 2. Metabolic malfunction. As you get older, your chances of having a negative drug reaction go UP. That’s because your kidneys and liver can slow down with age…which means it takes longer for prescription drugs to be metabolized and cleared out of your body. As you keep taking your regular dose, the drug keeps building up in your bloodstream…and that can quickly cause cognitive side effects like confusion and memory loss. If you’re over 65, doctors can be quick to dismiss these symptoms as “normal for your age”…or misdiagnose it as typical dementia. They may not realize that simply stopping the drug could reverse your symptoms! 3. Medication reactions and interactions. Taking more than one drug increases your risk of side effects and interactions. The average American over 65 is taking five prescription drugs at once. Once you reach your 80th birthday, you’re likely to be taking 18 prescriptions per year…and you can bet these don’t come with a warning about sudden dementia! But they should. Certain drugs are known to have dramatic—and even terrifying—effects on the brain. There have been countless highly publicized episodes of total amnesia caused by the popular insomnia drug Ambien®. It goes far beyond sleepwalking… People have “sleep driven,” cooked, shopped, and even committed crimes without any memory of it whatsoever while under the influence of Ambien. A group of antidepressants known as benzodiazepines are another well-documented troublemaker, especially for people over 65. You’ll recognize the names—I’m talking about Xanax® (alprazolam), Valium® (diazepam), Ativan® (lorazepam), and Klonopin® (clonazepam). Considering that 9% of ALL Americans between 65 and 80 take a “benzo” drug…it’s safe to say physicians hugely underestimate the dangers of these prescriptions. “That’s an extraordinarily high rate of use for any class of medications,” according to Michael Schoenbaum, a senior adviser at the National 3 Institutes of Mental Health. Mixing antidepressants with other drugs—especially antihistamines and anti-anxiety drugs—is another dangerous combination for your brain. But that’s not the worst of it… dementia, as well. Research published in the Journal of the American Medical Association shows that these drugs can cause lasting brain damage over time. A study of more than 3,400 people showed that those with a higher cumulative use of anticholinergic drugs were more likely to develop dementia. 87 ways to put yourself on the fast track to sudden dementia How modern medicine is fueling the sudden dementia epidemic A class of drugs known as anticholinergic drugs are some of the worst offenders for your brain—and there are at least 87 of them on the market right now. In fact, this is the type of drug Charles Donahue was taking in the case study I shared with you in Chapter 1. In addition, there’s a troubling trend in mainstream medicine that’s fueling the sudden dementia epidemic. It’s a treatment approach known as polypharmacy— that is, using smaller doses of multiple drugs to treat the same problem. This is not necessarily better! The more drugs you are on, the more side effects you can have, regardless of the dose. What makes these drugs so dangerous for your brain is that they interfere with one of your most important neurotransmitters—acetylcholine (ACh). Without ACh, messages can’t travel throughout your brain. You need it for quick, clear thinking…decision making…recalling important details…following directions…and so much more. But here’s the scariest part. These drugs are used for so many different conditions—from cholesterol to asthma to allergies to depression to overactive bladder—and that means you could be taking several of them at once without even realizing it. Some are even available over the counter. Many drug categories with the prefix “anti”— antihistamines, antidepressants, antipsychotics, antispasmodics, antiparkinsonians, and some antihypertensives—have anticholinergic activity. A few examples include antihistamines like Benadryl®, antidepressants like Elavil®, antipsychotics like Thorazine®, drugs for overactive bladder like Detrol®, and cholesterol-lowering drugs such as Crestor®. Working together, they can put you on the fast track to sudden dementia. And it’s not just sudden dementia that you have to worry about with anticholinergic drugs…but typical 4 Curing Sudden Dementia If you’re taking a drug for health concerns like blood pressure, cholesterol, acid reflux, insulin resistance, menopause symptoms, prostate problems, or even pain…there are safe, natural alternatives out there for you. You’ll find many of them in my recent book, The Natural Healing “Master List,” and featured in my monthly newsletter, Logical Health Alternatives. In the meantime, I’ll show you some simple, powerful ways you can help improve your brain health and keep your memory strong. ___________________________________________ Important note: DO NOT make any changes to your medication schedule without first consulting your doctor and reading the important warnings in Chapter 3 of this report. Stopping certain medications abruptly may cause harm. CHAPTER 3: THE ONE ACTION YOU CAN TAKE TO REVERSE SUDDEN DEMENTIA The first thing I do when a new patient comes to my office is review the complete list of medications he or she is taking…and discontinue any that may be unnecessary. The fewer drugs you can take, the better. I pay special attention to any drugs that are listed on my Sudden Dementia Watch List—that is, drugs associated with memory loss and confusion. I also look for any drugs that could increase a patient’s long-term risk of developing dementia. In other words, some prescription drugs can attack your brain quickly and slowly. Are you at risk? Check the Sudden Dementia Watch List Remember, a single dose of ANY medication could be enough to trigger symptoms of sudden dementia. That’s why it’s important for you to know your risk does increase with each additional prescription drug you take—whether or not it’s on this list. In fact, if you’re taking 5 or more prescription drugs…you are 930% MORE LIKELY to suffer from sudden dementia, according to data from the Annals of Internal Medicine. The Sudden Dementia Watch List (on the following page) includes drugs that are most likely to cause memory loss, cloudy thinking, confusion, and other cognitive symptoms…but they’re not the only drugs you need to worry about. Anyone at any time can have a negative reaction to any prescription drug. It can happen to you even if you’ve been taking a certain drug for years—so it’s important to be vigilant, for yourself and your loved ones. If you suspect that prescriptions are causing foggy thinking, confusion, or any other cognitive side effects in yourself or a loved one, call the doctor right away. I’ve shown you how prescription drugs can cause sudden dementia…and I’ve shown you which drugs could put you at the highest risk. So the next step is to take action. The only way to reverse the effects of sudden dementia caused by prescription drugs…is to wean off of them. Please note that it is extremely important that you work with a physician, consultant pharmacist, or other experienced medical professional to do this safely. Some drugs cannot be stopped “cold turkey” and must be “stepped down” with the help of a medical professional. Stopping certain drugs too abruptly can cause a rebound effect—and this can be dangerous or even deadly. Examples of drugs that require careful weaning include—but are not limited to—the following: • Antidepressants (e.g., Zoloft, Xanax). Stopping these drugs suddenly can make your anxiety or depression symptoms worse. In some cases, it can cause mania. You could also experience nausea, vomiting, tremors, mood swings, headaches, loss of coordination, flu-like symptoms, or dizziness. •Cholesterol-lowering statin drugs (e.g., Lipitor, Zocor). Stopping these drugs abruptly can cause a heart attack or stroke. Withdrawing the drug can cause your cholesterol and C-reactive protein (CRP) levels to shoot up very high. • Beta-blockers (e.g., propranolol, metroprolol, atenolol). Discontinuing beta-blockers too quickly can cause a heart attack. Other withdrawal symptoms include a rapid heart rate, angina and high blood pressure. 5 Sudden Dementia Watch List: Prescription drugs that increase your risk of memory loss Drugs to treat allergies and asthma • Allegra (fexofenadine) • Beclovent, Qvar (beclomethasone) • Benadryl (diphenhydramine) • Chlor-Trimeton (chlorpheniramine) • Claritin (loratadine) • Prednisone • Pulmicort (budesonide) • Tavist (clemastine) • Zyrtec (cetirizine) Drugs to treat anxiety and depression Note: Some of these drugs are also used to treat sleep disorders • Atarax (hydroxyzine) • Elavil (amitriptyline) • Klonopin (clonazepam) • Librium (chlordiazepoxide) • Norpramin (desipramine) • Paxil (paroxetine) • Prozac (fluoxetine) • Sinequan (doxepine) • Tofranil (imipramine) • Vivactil (Protriptyline) • Xanax (alprazolam) Drugs to treat bladder problems • Detrol (tolterodine) • Enablex (darifenacin) • VESIcare (solifenacin) Drugs to treat cardiovascular disease • Lanoxin (digoxin) • Norpace (disopyramide) • Procardia (nifedipine) Drugs to treat diabetes • Glucophage (metformin) Drugs to treat gout • Colcrys (colchicine) 6 Curing Sudden Dementia Drugs to treat heartburn, reflux and ulcers • Nexium (esomeprazole) • Prevacid (lansoprazole) • Prilosec (omeprazole) • Pro-Banthene (propantheline) • Tagamet (cimetidine) • Zantac (ranitidine) Drugs to treat high cholesterol • Crestor (rosuvastatin) • Lipitor (atorvastatin) • Mevacor (lovastatin) • Pravachol (pravastatin) Drugs to treat high blood pressure • Inderol (propranolol) • Lasix (furosemide) • Tenormin (atenolol) Drugs to treat pain • Codeine • Ultram (tramadol) Drugs to treat Parkinson’s disease • Akineton (biperiden) • Artane (trihexyphenidyl) • Cogentin (benztropine) Drugs to treat psychosis Note: Some of these drugs are also used to treat anxiety and depression • Clozaril (clozapine) • Mellaril (thioridazine) • Seroquel (Quetiapine) Drugs to treat sleeping disorders Note: Some of these drugs are also used to treat anxiety and depression • Ambien (zolpidem) • Halcion (triazolam) • Valium (diazepam) • Zimovane (zopiclone) • Muscle relaxants (e.g., baclofen). After long-term use, a quick withdrawal can cause hallucinations, anxiety, seizures, and other dangerous side effects. I work closely with my patients to taper the effects of any unnecessary or dangerous drugs they’re taking, and monitor them for rebound or withdrawal symptoms. Types of drugs that deplete vitamin B12 Antibiotics: Including amoxicillin, ciprofloxacin, tetracycline, neomycin, cefprozil, and similar drugs Anti-convulsant drug: Phenobarbital Anti-diabetic drug: Metformin Birth control pills that contain estrogen Then, I help them find natural solutions to help them achieve optimal health. Corticosteroids (inhaled, oral, or topical): Including budesonide (Pulmicort®), hydrocortisone, prednisone and similar drugs Remember, there are some cases where prescription drugs are necessary. I do write prescriptions from time to time at my clinic, but it’s rare. Most of my patients never need them, because there are safe alternatives to prescription drugs for just about every health problem under the sun. H2 Blockers: Including ranitidine (Zantac®), cimetidine (Tagamet®) and similar drugs Proton Pump Inhibitors: Lansoprazole (Prevacid®) and Omeprazole (Prilosec®) (My recent book, The Natural Healing “Master List,” includes a long list of ways you can improve your health without drugs…and I update the “master list” every month in my newsletter, Logical Health Alternatives.) It’s easy to talk about getting off prescription drugs, but I know it can be more difficult to do. It’s important to find someone you can trust. If your physician isn’t willing to listen to your concerns or work with you, find one who will. To help you get started, turn to Chapter 4 to find out the first thing you should do before going in to see your doctor about this. Then continue reading to find out what you can do right now to heal your memory naturally. 7 CHAPTER 4: DO THIS BEFORE YOUR NEXT DOCTOR’S APPOINTMENT Above all, I want to help you find natural health solutions that don’t need a prescription. But until you can work with a professional to reduce or eliminate prescription drugs, here are some simple things you can do to get a handle on the situation. First, it’s important to know ALL the drugs you’re taking—and what each one is for. So many patients come to see me with no idea why they are taking certain medications. It’s important for you to know…and for every one of your doctors and specialists to know. So before your next doctor’s appointment, here’s what I want you to do: Create a simple medication chart. I’ve included a blank chart on the next page, but it’s simple to make one at home and update it as necessary. All you have to do is draw three columns on a piece of paper. Column 1: Write down ALL medications you are taking. Be sure to include: • All prescription medications • All over the counter medications that you are taking right now, or take frequently (don’t forget allergy medicines, cold medicine, and pain relievers) • All nutritional supplements you are taking Column 2: Next to the name of each medication, write down the dose and how many times per day you take it. Column 3: Write down what each prescription, OTC product and nutritional supplement is for. 8 Curing Sudden Dementia Important: If you do not know the reason you are taking every medication, be sure to ask your doctor. If you discover that you’ve been prescribed multiple drugs for the same reason, ask if all of them are truly necessary. At every appointment, mention any and all side effects you’re experiencing or any changes you’ve noticed since you began taking the drugs—or anything that has changed since your last visit. If you’re seeing multiple doctors and specialists, it’s important to make sure they all have a complete list of prescriptions, over-the-counter medications, and nutritional supplements you are taking. Bring this chart with you each time. Your pharmacist can also be on the lookout for known interactions between drugs—so get them all filled at the same pharmacy whenever possible. And in the meantime…keep reading to find out what you can do to heal your memory naturally… Medication Chart for ___________________________________________ Name of Medication (Include prescriptions, supplements and over-the-counter medications) Dosage and Timing Purpose of Medication 9 CHAPTER 5: HEAL YOUR MEMORY NATURALLY After decades of research and billions of dollars spent, mainstream medicine has come up emptyhanded on Alzheimer’s and dementia. Yet they’re no closer to solving this devastating, deadly epidemic than they were decades ago. Why? Because they’ve missed the forest for the trees… They’re so hung up on plaques and tangles, they’ve utterly ignored the most obvious symptom of Alzheimer’s that shows up 10 years before the disease really starts to take hold. I’m talking about brain shrinkage. Brain shrinkage is just what it sounds like: a loss of neurons (and the connections between them) that results in your brain getting smaller. It’s a fact, a brain riddled with Alzheimer’s shrinks up like a grape in the summer sun…utterly devastating areas involved in thinking, planning and memory. The official term is “cerebral atrophy.” It can be generalized—meaning the entire brain shrinks at the same rate. This type typically results in a decrease in short-term memory. But brain shrinkage can also target certain areas— which is especially concerning if it occurs in the parts of the brain responsible for conscious thought and voluntary processes. But, ultimately, both kinds of brain shrinkage can lead to dementia and Alzheimer’s disease. And mainstream medicine has no drugs, treatments, or therapies to combat it. But that doesn’t mean brain shrinkage is something you just have to accept. In fact, recent research has shown three simple nutrients may be all you need. And not just to slow brain shrinkage…but actually reverse it. 10 Curing Sudden Dementia Reverse brain shrinkage with this pennies-per-day vitamin cure Just last year, an Oxford University study proved that a “pennies-per-day” all-natural cocktail of three simple B vitamins can halt brain shrinkage in its tracks. The astonishing results, published in the renowned medical journal The Proceedings of the National Academy of Sciences, showed that patients with mild to moderate brain shrinkage who took vitamin B6, vitamin B12, and folic acid slowed brain shrinkage by an unheard of 90%! Yes, I said 90%! Put simply, this treatment is pulling patients back from the abyss of Alzheimer’s. And if that sounds crazy to you, I can assure you no one was more surprised than the researchers themselves… Even senior author of the study, A. David Smith, was caught totally off guard, saying, “It’s a big effect, much bigger than we would have dreamt of, I find the specificity of this staggering.” And it’s an effect you can see with your own eyes. Researchers took MRI scans of patients’ brains and highlighted the specific areas that were protected by this natural cocktail…and amazingly, they all lined up perfectly with areas normally ravaged by Alzheimer’s disease. After viewing the MRIs, Paul Thompson, professor of neurology and head of the Imaging Genetics Center at UCLA School of Medicine said, “I’ve never seen results from brain scans showing this level of protection.” In fact, the only thing more impressive is the effect these three, simple B vitamins have on memory. An earlier study performed in 2012 showed that patients taking vitamin B6, B12, and folic acid trounced their placebo-taking peers by a whopping 69% on memory tests! As lead researcher David Smith of Oxford University put it… “It’s the first and only disease-modifying treatment that’s worked” And with rates of Alzheimer’s expected to skyrocket in the coming years to 115 million Americans (or 1 in 3)…it couldn’t have come along at a better time! Jess Smith, a communications officer for the U.K. Alzheimer’s Society, says this simple treatment has the power to “halve the number of people dying from [Alzheimer’s].” But don’t expect your doctor to recommend anything but pharmaceuticals anytime soon…Why? Because the money generated from Band-Aid-like Alzheimer’s drugs adds up to over $600 billion dollars a year. Put another way, Alzheimer’s disease is simply too big to cure. And as you’ve seen—it’s only going to get bigger. Pharmaceutical companies (and the FDA who gets paid to approve their products) simply have too much to lose by publicizing a pennies-per-day natural treatment with the potential to wipe out Alzheimer’s for good. But if you or a loved one are suffering from Alzheimer’s, you don’t have to wait! I’ve seen in my own patients the remarkable effects these three simple B vitamins can have on cognitive function—and on overall health. So if you’re not already supplementing with B vitamins, it’s time to get started. The doses used in the studies were: • 500 micrograms of vitamin B12 • 20 milligrams of B6 • 800 micrograms of folic acid You can get quality B vitamin supplements in any natural food store or vitamin shop, as well as from online supplement retailers. The dosages will be listed in micrograms. And upping your intake of foods rich in these nutrients certainly won’t hurt either. Here’s where you can get them: • Vitamin B12: Animal products like fish, poultry, meat, and eggs are your best sources (clams and liver are particularly rich in this nutrient). • Vitamin B6: Tuna, chicken, turkey, and cantaloupe offer up a good dose of B6. • Folic acid: Spinach and other dark green leafy vegetables are good sources. But there’s one more simple thing you can do to help prevent brain shrinkage… A bigger brain and a better memory with fish oil Another boon in the war against brain shrinkage is something I’ve talked about many times before—fish oil. But it bears repeating. Especially since research on its benefits for brain health is so incredible. For instance, the journal Neurology recently published a study examining data from over 1,000 postmenopausal women participating in the Women’s Health Initiative Memory Study. The data spanned eight years, and included the subjects’ levels of EPA and DHA, as well as brain volumes (measured by MRI). The results were stunning. Women with higher omega-3 levels—and DHA in particular—had significantly larger brain volumes than women with low levels. Another major benefit: increased size of the hippocampus, which happens to be your brain’s memory center. So you can see why preserving it is so important. And there are plenty more studies just like this one— all showing fish oil’s positive effects on the brain. 11 Another one, published in 2014, included 193 Alzheimer’s disease patients, 397 people with mild cognitive impairment (MCI) and 229 people with normal brain function. At the beginning of the study, 117 of the participants reported that they regularly used fish oil supplements (and most of them continued to take them throughout the study period). All of the patients underwent cognitive testing and brain imaging at the outset of the study, and then at 6to 12-month intervals. The researchers noted that the patients taking fish oil showed less brain shrinkage on scans than the rest of the participants. Plus, those who used fish oil had better scores on cognitive function tests at any given time over the course of the study. I recommend at least 3,000 mg of EPA and DHA from fish oil every day. As you can see, warding off brain shrinkage and Alzheimer’s disease can be simple to do with B vitamins and fish oil. But if you’re looking for something that can deliver a quick “brain boost,” you’ve got to see this… Squash “senior moments” in as little as 1 HOUR with the exclusive Bavarian Brain Booster my patients are raving about How many times in the last year have you walked into a room and forgotten why you’re there? Misplaced your car keys? Drawn a blank while trying to remember the name of a childhood friend? Some doctors dismiss these memory lapses as “senior moments.” They tell you it’s a natural part of aging and there’s nothing you can do about it. Or they suggest you exercise your brain by doing crossword puzzles…or watching Jeopardy…or memorizing your family’s phone numbers. 12 Curing Sudden Dementia Don’t get me wrong—I’m all for mental workouts. But they’re more for the long-term health of your brain. And let’s face it—doing a math problem in your head isn’t going to help you remember where you put the dog’s leash when he’s begging for a walk. But what if I told you it’s possible to substantially improve your memory in just one hour? And that you can keep your focus and concentration strong and steady? And even reduce stress and improve your mood? And what if I told you that you could do all of these things completely naturally? In fact, research shows that one common herb can produce all of these cognitive breakthroughs. Thousands of varieties—but only 1 scientifically verified to give you razor-sharp thinking I’m talking about lemon balm, scientifically known as Melissa officinalis. As I mentioned above, lemon balm is incredibly common. It’s a member of the mint family and grows just about everywhere. And there are thousands of varieties. But only one is scientifically verified to improve your memory, focus, word recall, and brainpower. And boost your overall cognitive strength. It’s called Bluenesse®. And it’s made from the extract of a special type of lemon balm only grown in Bavaria, Germany. In fact, it took scientists and farmers a year to develop this particularly potent variety of lemon balm. And now the specific variety of this plant—and the exact locations of the farms where it’s grown—is being guarded like a state secret. The neuroscientists who developed Bluenesse formed a carefully vetted private network of farmers to grow it in ideal locations all across Germany. And they even started a second backup farm in another European country. (I was able to get some insider intel on this—it’s in Poland.) In fact, this specialized botanical is even protected by intellectual property laws. And the farmers who know about it are the ONLY growers on Earth who are cultivating this “mental miracle.” Why all the secrecy? When I pressed my connections for details, I discovered something pretty impressive. Turns out, the neuro-researchers who uncovered this rare lemon balm—and worked tirelessly to test, verify, and document its effects—have a good reason for being selective about who they share the details with. They want to shield you from impostors by keeping their supply under tight control. They’re so serious about it that they test every… single…batch of Bluenesse to make sure it’s active, and that it meets their exact specifications. From the size of the leaves to the unique composition of the essential phytonutrients. They use an innovative scientific method of testing known as “bioassay guided technology.” So let there be no confusion about this one: Everything I’m about to show you today is only possible with the Bluenesse variety, cultivated exclusively by that specialized network of German farmers. Top neuroscientists have discovered that no other strain of lemon balm can do what Bluenesse can do. I’m so impressed by this “Bavarian Brain Booster” I actually worked with the manufacturer to bring Bluenesse to the U.S. And I’m the first doctor in the country to use it. The results in my patients have been phenomenal. But there are also several scientific studies that show just how effective Bluenesse is for memory and focus. Let’s take a closer look at how Bluenesse can accomplish so much. Taking the benefits of lemon balm to the next level There’s quite a bit of research showing that lemon balm can help soothe stress away. It contains active ingredients that ensure your brain gets optimum amounts of GABA, an amino acid that helps you feel calm. And lemon balm also contains compounds that help increase your levels of dopamine, the brain’s feel-good chemical. Bluenesse contains these same relaxing properties. Which is great. But here’s what I really love about Bluenesse: It’s been specifically developed to enhance other compounds in lemon balm that improve cognitive performance. Bluenesse improves memory and increases focus and concentration by activating your brain’s M1 receptors. M1 sounds a bit like a Bond villain. But it’s actually a very tiny, yet very powerful type of brain cell. M1s are in charge of a process called oscillation—which makes sure information flows freely between your brain cells. Oscillation is a big deal. It’s the only way you can store and retrieve your memories, learn new tasks, and stay focused. It’s also how your brain handles spatial awareness. In other words—how much space you have to maneuver around. Thank oscillation for being able to walk through your house without tripping over furniture Rob Petrie-style. If your M1s aren’t activated properly, your brain feels sluggish. It’s harder to remember things. Your focus seems fuzzy. And you don’t seem to come up with answers or new ideas like you used to. In essence, you have “senior moments.” But thanks to new in vitro research, we now know that Bluenesse can actually activate M1 receptors in 13 the brain. And that helps the brain feel young again. Just take a look at the effects in clinical trials… Sharper focus and revitalized working memory within an hour In a study published last year, researchers gathered 25 healthy men and women under the age of 40. You might think people that young wouldn’t have many memory or concentration issues. But guess what? Within one hour of taking 300 mg of Bluenesse, the study participants had a 13.5% improvement in memory and focus, compared to the participants in the placebo group. To make sure these results weren’t a fluke, the researchers conducted a second study. They gave 21 healthy men and women, ages 21 to 30, either 300 mg of Bluenesse, or a placebo. Then they gave these study participants the same cognitive tests they gave the people in the first study. One of those tests measured participants’ working memory. Working memory is the way you keep track of new facts, figures, and details you see every day. It’s what helps you remember where you parked your car at the mall or which ingredients you’ve already added to the pot of chili simmering on the stove. The Bluenesse groups aced this test. In fact, the placebo group’s test scores actually plummeted, while the Bluenesse group’s scores increased. Rev up your recall abilities and stay cool, calm, and confident for hours The Bluenesse groups also significantly outperformed the placebo groups in a test in which they saw 10 words for two seconds each, with a second in between each word. Immediately after all of the words flashed on the screen, the participants were asked to write down as many words as they could remember. 14 Curing Sudden Dementia Then, 20 to 25 minutes later, they were asked to recall the words again. This tests long-term memory, or what I call “high-performance memory”—the ability to remember names, dates, places, and all of those security passcodes you have to create. In both studies, the Bluenesse groups’ memory and focus just kept improving. And their overall mental state improved as well. In fact, even three hours after taking Bluenesse, participants described themselves as “calm,” “steady,” “self-confident,” and “comfortable.” New research confirms this Bavarian Brain Booster is the real deal Those results are impressive enough on their own. But there’s also a brand new study on Bluenesse. Twenty-five men and women, ages 19 to 36, got either 600 mg of Bluenesse or a placebo. They then took a working memory test and word recognition test similar to the ones in the studies I mentioned above. Just like in the previous studies, the Bluenesse group scored significantly better on these tests than the placebo group. And, once again, the improvements were noticeable within an hour of taking Bluenesse. Pretty incredible, right? And I expect the research on Bluenesse to just keep on coming. Research that offers even more proof of how this unique variety of lemon balm can help your brain feel young again. As I mentioned above, I’m the first doctor in the U.S. to use Bluenesse. It’s one of the main ingredients in my BrainLogic formula, which you can order through my website, www.drpescatore.com. My patients have already noticed that they’re able to think faster and more accurately. And they’re thrilled to finally be free of those “senior moments” they’d resigned themselves to living with. And the amazing thing is this can happen just one hour after taking Bluenesse. But I recommend taking 300 mg every day to ensure your brain keeps firing on all cylinders…all day long. Patients sometimes ask me, “When’s the best time of day to take Bluenesse?” If you’re not a morning person, you might want to take it as soon as you wake up. Think of it as a way to “activate” your brain, to get ready for anything the day has to throw at you. It can help you be bright and alert by the time you’re ready to step out the door. And if you need extra focus in the afternoon—for an important meeting, or a big project you’re working on—it’s OK to take it again. This “double-strength” dose (600 mg) has also been shown to have powerful effects on alertness, while warding off fatigue and stress. And of course, there are two more “Brain Basics” you should be taking right now: vitamin D and vitamin E. Let me show you why I recommend those to every single one of my patients… Tack decades onto your brain’s lifespan—and your own—with vitamin D There’s a good reason I talk about vitamin D so often. It’s because new research emerges every day showing this critical compound can save your life—if you’re getting enough of it. New studies are published every month, it seems, showing how powerful this vitamin really is. So I’d like to take some time to share them with you. A team of New York researchers compared cognitive function among 253 very elderly subjects—ranging from 95 to 109 years old—to 2,451 National Health and Nutrition Examination Survey (NHANES III) participants over the age of 70. Tests showed low levels of vitamin D correlated to mental decline in both groups. But the exceptionally long-lived group had insufficiency rates comparable to NHANES subjects, despite being as much as 25 years older. These results suggest that longer-lived people have higher levels of the sunshine vitamin on average— and better cognitive function well past the age of 90 because of it. And that’s not all vitamin D does for your neurological health. Yet another study showed that higher levels of D can help stem the progression of multiple sclerosis. Why you still need more D than you probably think If you haven’t had your 25-hydroxyvitamin D levels tested recently—or ever—make an appointment with your doctor to get it done ASAP. Especially if you’re suffering with a chronic or life-threatening disease like diabetes or cancer. Once you’ve established your current vitamin D level, you should be re-tested every six weeks, until your levels are where they should be. And speaking of vitamin D levels… A level of 30 might be sufficient. But it’s certainly not optimal. You want to aim for closer to 80 ng/ml instead. Unfortunately, most people don’t have levels that high right out of the gate. That’s why I make vitamin D status a top priority at my office. I regularly test every single one of my patients to assess their blood levels. And I almost always prescribe a daily supplement. To reach an optimal vitamin D level, most people need more than the maximum 2,000 IU per day most doctors will recommend to their deficient patients. (That is, if they even test for D in the first place— much less recommend vitamins.) To effectively restore healthy D levels, I generally prescribe 10,000 IU of vitamin D3 on a daily basis to my patients. And a lot of times, they’re shocked (and a little nervous) to take a dosage this high. But as long as your blood 15 levels are screened regularly, there’s no reason to take any less. I take 10,000 IU every day myself. And I feel better than ever. After following this protocol for a few weeks, my patients say the same. Frankly, this dose might be “high”—but it’s the amount many people need to keep their blood levels between 80 and 100. Of course, you may be wondering if the arrival of summer—and more sunshine—means you can reduce or even eliminate your vitamin D supplement. Well, it depends. As I’ve mentioned many times before, sunshine is an effective way to boost your vitamin D levels. (The best way, actually.) But this strategy comes with some critical caveats. You can supplement with lower doses of D during the summer IF you get full mid-day sun exposure over most of your body. Without sunscreen. For 20 minutes per day. Every day. But in order to eliminate it altogether, you’d also have to live in South Florida or the very Southern part of Texas. If you don’t, you absolutely must take your vitamin D. Every day of the year. My minimum recommendations are 2,000 to 5,000 IU of D3, regardless of the season. And if you don’t get outside much thanks to long days at the office, you may still require 10,000 IU—even in the dog days of summer. You won’t know for sure until you get tested. So, once again, if you haven’t had your levels measured lately, ask your doctor to check them today. recently concluded that if we don’t get enough vitamin E, we’re depriving ourselves of more than half of the components necessary to build and maintain our brains. She based this observation on a study of zebra fish. Of course, fish brains aren’t nearly as complex as ours, but the same basic principles apply. The researchers gave some of the fish a diet rich in vitamin E for nine months. The other fish got no E. At the end of the study, the researchers looked at the fish brains and discovered that the ones that didn’t get enough vitamin E had a one-third reduction in DHA. And they also had 60 percent less of a biochemical that helps transport DHA from the body into the brain. I’ve told you about DHA before—it’s an essential omega-3 fatty acid that you most commonly find in fish oil, along with EPA. It can help prevent heart disease, lower inflammation, and even reduce the signs of aging. And it helps your brains function properly. In fact, if you don’t get enough DHA, your brain cells can actually die. Another vitally important discovery the researchers made is that vitamin E appears to prevent a type of fat oxidation that is thought to be one of the causes of dementia. Which leads me to the other recent study about vitamin E and Alzheimer’s drugs. In fact, one study shows that vitamin E can work even better than a common dementia drug in people with moderate to severe Alzheimer’s disease. In this study, researchers gathered 613 people with mild to moderate Alzheimer’s disease and divided them into four groups. One group got 2,000 IU of vitamin E every day for an average of about two years. The second group took the popular Alzheimer’s drug memantine (brand name Namenda). The third group took vitamin E plus memantine, and the fourth group got a placebo. The evidence is so compelling, one researcher The researchers discovered that the vitamin E group Stave off dementia with vitamin E Plenty of research shows that vitamin E is important for brain function. But new studies are proving just how essential this key nutrient is as we get older. 16 Curing Sudden Dementia had 19 percent less functional decline per year than the placebo group. Basically, this means that they were still able to do things like cook, wash, and shop, which allowed them to live independently longer. You’d think this would be the same for the memantine group, but the researchers found that the drug didn’t appear to stop functional decline at all. Nor did memantine combined with vitamin E. They think that’s probably because the drug interferes with how our bodies metabolize vitamin E. So, bottom line, it’s a good idea to make sure you get adequate vitamin E at any age— and especially after your 50th birthday. I recommend 400 IU per day of natural vitamin E with mixed tocopherols (d-alpha tocopherol). Synthetic E (dl-alpha-tocopherol) isn’t absorbed as well in the body, and it’s only 67 percent as active as the natural form, so you would need to take more. 15 minutes could save your brain… And last but not least… I prescribe exercise to every one of my patients. Before you give up on that idea, please hear me out. You don’t have to take up some extreme cardio craze…or spend hours a day at the gym. At the very least, you can do one simple thing: Take a 15-minute walk every day. A major study in the prestigious medical journal Lancet shows that exercise is KEY to curbing Alzheimer’s disease risk. And not just a little bit. We’re talking about completely eliminating HALF of the cases of this horrible, deadly disease. And the good news is, all you need is a short walk every single day. (Yes, every day.) Take your dog. Take your spouse. Take a friend. Just keep it up and your brain will reward you! Final Thoughts You should know that most chronic conditions CAN be successfully treated without prescription drugs—so please do not give up hope. I’ve helped patients achieve better health without drugs for more than 20 years. Every issue of my monthly newsletter Logical Health Alternatives and daily Reality Health Check e-alerts are written with this goal in mind. Please visit my website at www.drpescatore.com for more ideas that are easy and even fun, to help you feel better, look better, and even eat better than you ever have before. I look forward to helping you on your journey to health. 17 18 Curing Sudden Dementia 19 Fred Pescatore, MD A L T E R N AT I V E S Visit Dr. Fred online! www.drpescatore.com Stay up-to-date on his very latest health breakthroughs and solutions as well as special TV guest appearances and events. You’ll find frequently asked questions, article archives, and an exclusive Subscribers-Only center where you can access your issues and free bonus reports online. You can also search back issues for past topics. Check it out for more healing tips and solutions today! ©Copyright 2016, OmniVista Health Media, L.L.C. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including recording, photocopying, or via a computerized or electric storage or retrieval system without permission granted in writing from the publisher. The information contained herein is obtained from sources believed to be reliable, but its accuracy cannot be guaranteed. All material in this publication is provided for information only and may not be construed as medical advice or instruction. No action or inaction should be taken based solely on the contents of this publication; instead, readers should consult appropriate health professionals on any matter relating to their wealth and well-being. The information and opinions provided in this publication are believed to be accurate and sound, based on the best judgment available to the authors, and readers who fail to consult with appropriate health authorities assume the risk of any injuries. The publisher is not responsible for errors or omissions. For additional copies or questions, please contact ReaderServices at www.drpescatore.com OV1R002426