Download renal physiology tutorial discussion

RENAL PHYSIOLOGY
TUTORIAL DISCUSSION
Dr. Zahoor
TOPICS
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Nephron
Glomerular Filtration
Tubular Reabsorption (Lect 3 & 4)
Tubular Secretion
Q1. What are functions of kidney?
Q2. What are components of
nephron?
Q3. Draw the nephron and label its
parts.
Q4. What are differences between
cortical and juxta medullary nephron?
Q5. What is vasa recta?
Q6. What is juxta glomerular
apparatus and what is its function?
Q7. What is Glomerular Filtration?
Q8. Define Glomerular Filtration Rate?
Q9. Name the 3 layers of Glomerular
membrane.
Q10. Is the Glomerular membrane
more permeable or less permeable
than other capillaries. Give reason.
Q11. Basement Membrane of
Glomerular membrane has positive or
negative charge. What is the
importance?
Q12. When blood passes through
glomerulus, what blood substances
are NOT filtered?
Q13. Write the full word and value for
- PGC
- πGC
- PBS
Full word
________
________
________
Value
______
______
______
Q14. How much is the Net Filtration
Pressure?
Q15. What factors increase or
decrease GFR? Give five factors.
Q16. Kf (Filtration Coefficient)
depends on what factors?
Q17. Name two mechanisms
responsible for Autoregulation in
kidney.
Q18. What is the range of mean
arterial blood pressure, when kidney
is doing Autoregulation?
Q19. How much is
- Renal Blood Flow _________
- Renal Plasma Flow _________
- GFR - _________
Q20. What is filtration fraction? How
much is it?
Q21. Name the two substances used
to measure GFR.
Q22. Name the blood constituents
present in the glomerular filtrate.
Q23. After filtration, how much
percentage of the following
substances is reabsorbed in the
tubule
Water ___ %
Sodium ___ %
Glucose ___ %
Q24. GFR is 125ml/min, how much
amount of water is normally
reabsorbed in the tubule?
Q.25. How much percentage of the
following substances is reabsorbed in
PCT
Na+ _____
H2O _____
Q26. Na+ - K+ pump is operating
where in the epithelial cell, for Na+
reabsorption?
Q27. Name the hormone which helps
in Na+ reabsorption in DCT and CT.
Q28. What is JGA?
Q29. Renin is secreted from where in
the nephron?
Q30. What is the function of principal
cells? Where they are present?
Q31. What is function of ANP?
Q32. What is the function of ADH?
Where does it act?
Q33. Is Descending limb of LH
permeable to Na+
Q34. Is Ascending limb of LH
permeable to H2O?
Q35. Name the receptors where ADH
acts in the CT?
Q36. Name the channels where ADH
acts in CT.
Q37. Where ADH is produced?
Q38. Where ADH is stored?
Q39. What causes increase ADH
release?
Q40. If ADH is not there, how much
amount of urine person will pass?
Q41. What is Diabetes Insipidus?
What are two types of DI?
Q42. What is Secretion?
Q43. What is importance of
Secretion?
Q44. Name the substances secreted.
Q45. Where K+ is secreted?
Q46. Name the cells where K+ is
secreted in DCT and CT.
Q47. What is the control of K+
secretion in DCT and CT ?
Q48. What is the action of
Aldosterone on principal cells for K+
secretion?
Q49. In Hyperaldosteronism, what
happens to K+ secretion?
Q50. In Acidosis, what happens to K+
secretion?
Q51. Why K+ regulation is important?
Thank you