Download (Advanced Embryology) (120 marks)

Tanta University
Doctorate of science in Anatomy& Embryology
Faculty of Medicine
First part (Advanced Embryology) (ANAT 9001,9002)
Human Anatomy& Embryology Dep.
Number of Questions: 7 + 25
MCQ1/10/2016
Total: 120 Marks
Time Allowed: 3 Hours
Doctorate of Science in Anatomy& Embryology
First Part (Advanced Embryology) (120 marks)
Short notes (95 marks)
1- Describe the events of pre-embryonic development that result in the formation of
the blastocyst.
(10 marks)
2- Explain the development of primary germ layers and list the structures produced
by each layer.
(12 marks)
3- Differentiate between the embryo and fetus. Summarize the structural changes
that occur in the embryo between the 4th and 8th weeks of development.
(15 marks)
4- Mention:
A. Derivatives of the cardinal veins.(9 marks)
B. Skeletal derivatives of pharyngeal arches. (6 marks)
5- A. Discuss the gut tube herniation and rotation and its defects. Mention the
molecular regulation of the gut tube development.
(9 marks)
B. Explain the development and anomalies of the external genitalia in male.
(9 marks)
6- A. Discuss the spinal cord development and mention its molecular regulation.
(10 marks)
B.Explain the development of the internal ear.(4 marks)
7- A. Explain the development of the hair.(3 marks)
B. Describe the development of the viscerocranium.(4 marks)
C.Mention the development of the skeletal musculature and its innervation.
(4 marks)
WITH MY BEST WISHES
Chairman of Department: Prof. Dr. Mona Zoair
1
MCQ (25 marks):
1-The correct order for origin and migration of germ cells is:
a) Epiblast to yolk sac to ventral mesentery to genital ridge
b) Epiblast to yolk sac to dorsal mesentery to genital ridge
c) Epiblast to hypoblast to genital ridge
d) Epiblast to mesoderm to genital ridge
e) Epiblast to yolk sac to mesoderm to genital ridge
2- Which of the following is NOT a step involved in spermiogenesis prior to losing connection with Sertoli
cells?
a) Flagella lysis
b) Condensation of nucleus
c) Formation of neck region and tail
d) Loss of cytoplasm
e) Acrosome addition
3- After the Graafian follicle breaks and before fertilization takes place, the secondary oocyte is
surrounded by cells called:
a) Fimbriae
b) Zonapellucita
c) Cumulus oophorus
d) Acrosomes
e) Oocytes
4- Which of the following does NOT take place during fertilization?
a) Male pronucleus forms
b) Endometrial implantation occurs
c) Restoration of a diploid genome
d) Determination of genetic sex of the embryo
e) Cleavage initiated
5- The two layers of extraembryonic mesoderm are called:
a) Endoderm; Mesoderm
b) Primary; Secondary
c) Somatopleuric; Splanchnopleuric
d) Mesenchyme; Parachyme
e) Epiblast; Hypoblast
6-The notocord is composed of:
a) Mesoderm only
b) Endoderm only
c) Ectoderm only
d) Mesoderm and ectoderm
e) Mesoderm and endoderm
7- Lateral folding leads to the formation of an elongated:
a) Heart tube
b) Spinal tube
c) Allantois
d) Gut tube
e) Yolk sac
2
8- During the beginning of the embryonic period, the age of the embryo is expressed by …… and after
week four the age is expressed by …….
a) CRL; Somites
b) Somites; CRL
c) Tube diameter; Somites
d) Somites; Tube diameter
e) CRL; Tube diameter
9- Which structures remain most vulnerable to teratogens during the fetal period?
a) Vertebral column and back muscles
b) Esophagus and anus
c) Hands and feet
d) Liver and spleen
e) Eyes and brain
10 -Which of the following does NOT occur during weeks 26-29?
a) Lungs are not capable of breathing
b) The CNS is capable of controlling breathing and body temperature
c) Fat is beginning to accumulate
d) The spleen is still making blood cells
e) Pupillary light reflex is present
11-What structure does the middle third (conuscordis) of the bulbuscordis become?
a) Right Ventricle
b) Left Ventricle
c) Ventricular Outflow Tracts
d) Aorta & Pulmonary Artery
e) Left & Right Atria
12-Which of the following is NOT associated with an Atrial Septal Defect?
a) Persistent ostiumsecundum
b) Endocardial cushion defect
c) Sinus venosum defect
d) Probe patency
e) Transposition of the Great Vessels
13-What cardinal vein is responsible for draining the body wall
a) Subcardinal
b) Cacrocardinal
c) Supracardinal
d) Dorsal cardinal
e) Ventral cardinal
14 -The urorectal septum divides the ……. from the …….
a) Anorectal canal; Urogenital sinus
b) Urogenital sinus; Mesonephric duct
c) Urinary bladder; Allantois
d) Urachus; Allantois
e) Mesonephric duct; Ureteric bud
3
15- During development of the ovaries, the primitive sex (medullary) cords…….
a) Proliferate
b) Move laterally
c) Move medially
d) Differentiate
e) Degenerate
16- What structure in the indifferent stage (weeks 3-6) becomes the clitoris?
a) Urogenital groove
b) Genital swelling
c) Urethral fold
d) Perineum
e) Genital tubercle
17-The first stomach rotation causes the …… and …… vagus nerves to become the …….and ………vagal
trunks, respectively.
a) Left; Right; Superior; Inferior
b) Right; Left; Lateral; Medial
c) Left; Right; Lateral; Medial
d) Right; Left; Anterior; Posterior
e) Left; Right; Anterior; Posterior
18-A three-week old male infant comes into the emergency room for weight loss and acute dehydration.
The infant has been projectile vomiting and the condition is worsening. Which of the following is most
likely?
a) Gastric atresia
b) Pyloric stenosis
c) Annular pancreas
d) Malrotation of the gut
e) Intestinal duplication
19-The sulcus limitans splits the ____ layer into a dorsal(alar plates) and ventral part(basal plates).
a) Ventricular
b) Ependymal
c) Mantle
d) Marginal
e) Pseudostratified
20- Neural crest cells give rise to all of the following EXCEPT:
a) Parasympathetic ganglia of CN III, VII, IX, X
b) Sympathetic ganglia of V, VII, VIII, IX, X
c) Epidermis, hair, nails, cutaneous and mammary glands
d) CT around the developing eye and optic nerves
e) Pia and arachnoid mater of the occipital region
21- A tuft of hair on the back of a newborn is likely associated with:
a) Spina bifida occulta
b) Klippel-Feil syndrome
c) Spina bifida cystica (myelomeningocele)
d) Hypertrichosis lanuginose
e) Hemivertebra scoliosis
4
22- All of the following structures contribute to the thoraco-abdominal diaphragm EXCEPT:
a) Septum transversum
b) Pleuroperitoneal fold
c) Dorsal mesentery
d) Paraxial mesoderm
e) Fibrous pericardium
23-Facial defects can result from deficient ……. cells, which are important for the development of the
pharyngeal/ branchial arches.
a) Endoderm
b) Ectoderm
c) Mesenchyme
d) Intermediate mesoderm
e) Neural crest
24- Where does the hyaloid artery develop in relation to the optic stalk?
a) Along the outer layer
b) Between the outer and inner layer
c) Inside of the stalk
d) On the lateral surface of the choroid fissure
e) On the medial surface of the choroid fissure
25- Which of the following is NOT part of the chondrocranium?
a) Postchordal cartilage
b) Prechordal cartilage
c) Parachordal cartilage
d) Hypophysial cartilage
e) Olafactory, otic, and optic capsules
END OF THE EXAM
WITH MY BEST WISHES
Chairman of Department: Prof. Dr. Mona Zoair
5
Tanta University
Medical Doctorate in Anatomy& Embryology
Faculty of Medicine
First Part (Genetics& Molecular regulationHuman Anatomy& Embryology Dep.
Radiological Anatomy) (ANAT 9003)
Number of Questions: 7
Total: 60 Marks
5/10/2016
Time Allowed: 3 Hours
Medical Doctorate in Anatomy& Embryology First Part
Genetics& Radiological Anatomy (60 marks)
A- GENETICS& MOLECULAR REGULATION (30 Marks) :
1- Define the following:
A) Chargaff's rule
B) Genetic code
C) Nucleosome
D) Kinetochore structure
(10 marks)
2- Mention the clinical features of trisomy 18.
(10 marks)
3- Discuss the structural abnormalities of the chromosomes.
(10 marks)
________________________________________
B- RADIOLOGICAL ANATOMY (30 Marks) :
4-Define the following:
(8 marks)
A) Image
B) Contrast material.
C) Inface and inprofile
D) Flat plate
5- Discuss the mechanism, advantages and disadvantages of ultrasound.(7 marks)
6- Draw diagrams of:
A) CT at the level of T12.
B) CT at the level of L2
(8 marks)
7- Draw a diagram of MRI of the shoulder joint.
(7 marks)
END OF THE EXAM
WITH MY BEST WISHES
Chairman of Department: Prof. Dr. Mona Zoair