Download Module Specifications Institution: King Abdul

The National Commission
for Academic Accreditation
& Assessment
Endocrine Module
Specifications
Academic Year 2010/2011
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
Module Specifications
Institution: King Abdul-Aziz University
College/Department: Faculty of Medicine/ Endocrine Module
A- Course Identification and General Information
1. Course title and code: Endocrine System / SYS325
2. Credit hours: 4 hours
3. Course is offered: MBBS program
4. Name of faculty member responsible for the course:
Prof. Hassan Salah Abduljabbar
Dr. Zienab Alrefaie
5. Level/year at which this course is offered: Third year / Second semester
6. Pre-requisites for this course : Physiology courses:
- Autonomic nervous system
- Central nervous system.
Anatomy courses:
- Neuroanatomy.
7. Co-requisites for this course (if any)
8. Location : male &female :On main campus
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
B- Objectives
Endocrine System modules is designed to
Study the structure and function of the endocrine organs including the pituitary, thyroid,
parathyroid, adrenal glands and pancreas in relation health and disease states.
Also to study the relationship between the central nervous system and various endocrine
organs in order to let students become able to describe and analyse the conditions
affecting different hormones’ levels. The course helps students to provide the basis and
working knowledge for the common clinical conditions and disorders related to endocrine
system.
In addition, the course covers the topic of lactation and mammary glands, and the
very important topic of cancer breast
C. Course Description
Subjects
1. Topics to be covered
List of
topics
Anatomy
Lectures
 Histology of pituitary.
 Gross anatomy of pituitary.
 Histology of the thyroid and parathyroid
glands.
 Histology of adrenals
 Histology of mammary glands
 Histology of the pancreas
Practical
 Histology & anatomy of pituitary
 Histology of the thyroid and parathyroid
gland
 Histology of the adrenals.
 Histology of pancreas
Total
No. of
weeks
Contact
hours
6
4
10
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
Physiology
Lectures
 Endocrine System: an overview
 Hypothalamic Hormones
 Pituitary function and control of pituitary
hormones.
 Physiology of Thyroid Hormones
 Hormonal control of calcium homeostasis
 Physiology of the Adrenal hormones
 Control of adrenal glands’ function
 Physiology of lactation
 The physiology of pancreatic hormones
9
Tutorial
 Neuro-endocrine relationship.
 Thyroid and parathyroid function.
 Adrenal and pancreatic hormones.
3
Total
12
Biochemistry
Lectures
 Hormone receptors
 Biochemistry, biosynthesis & Lab.
Evaluation of thyroid hormones
 Structure and biosynthesis of steroids
 Laboratory assessment of adrenocortical
function
 Insulin and glucagons
5
Directed Learning
 Eicosanoids
Total
7
Pharmacology
Lectures
 Pharmacology of thyroid
 Pharmacology of parathyroid
 Corticosteroids and antagonists
 Anti diabetic drug therapy
 Oral hypoglycemic therapy
Directed Learning:
 Drugs of Pituitary and hypothalamic
disorders
5
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
Total
7
Pathology
Lectures
 Pituitary & hypothalamic pathology
 Pathology of thyroid
 Pathology of parathyroid
7
 Pathology of the adrenals
 Pathology of breast
 Cancer breast
 Pathology of the pancreas
Practical
 Pathology of thyroid / parathyroid
3
 Pathology of breast
 he pathology of pancreas
Tutorial
1
 Pathology of diabetes mellitus
Total
Medicine
Clinical Presentation
 Hyperthyroidism
3
 Hvperparathvroidism
 Diabetes mellitus
Tutorial
1
 Adrenal disorders
Total
Obstetric and gynecology
Clinical presentation
1
 Hirsutism
Total
Radiology
Tutorial
 Imaging of the thyroid ,adrenal and
1
pituitary glands
Total
General surgery
Clinical presentation
 Cancer Breast
Total
11
7
2
1
1
2
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
C. Course Description (Note: General description in the form to be used for the Bulletin or
Handbook should be attached)
2 Course components (total contact hours per semester):
Lecture
Tutorial
CL/PBL
SDL
Practical
32
6
5/1
2
7
2. Course Component
Department
Lect.
Anatomy
Physiology
Biochemistry
Pharmacology
Pathology
Medicine
Ob&Gyne
Radiology
General
surgery
PBL
6
9
5
5
7
Total hours
Tutor
cl. presentation
Pract.
PBL
SDL
4
3
2
2
1
1
3
3
1
1
1
total
10
12
7
7
11
7
2
1
2
8
67
3. Additional private study/learning hours expected for students per week. (This should
be an average: for the semester not a specific requirement in each week)
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
4. Development of Learning Outcomes in Domains of Learning
For each of the domains of learning shown below indicate:


A brief summary of the knowledge or skill the course is intended to develop;
A description of the teaching strategies to be used in the course to develop that
knowledge or skill;
The methods of student assessment to be used in the course to evaluate learning outcomes in
the domain concerned.
a. Knowledge
(i)
Description of the knowledge to be acquired:
By the end of endocrine Module the student will be able to:
a.i.1 Define the word hormone and list types of hormones according to structure.
a.1.2 Describe the mechanisms of hormone transport.
a.i.3 Define neuroendocrine hormone and give examples.
a.i.4 List types of hormonal receptors.
a.i.5 Describe action of different hormonal receptors.
a.i.6 List types and effects secondary messengers.
a.i.7 List endocrine functions of :
a. Liver.
b. Kidney.
c. Heart.
a.i.8 List hypothalamic hormones.
a.i.9 Describe hypothalamic hypophyseal connections.
a.i.10 Describe microscopic and macroscopic features of pituitary, thyroid, parathyroid,
adrenal, and mammary glands.
a.i.11 State gross and microscopic structures of pancreas
a.i.12 Describe morphology of pancreatic islets.
a.i.13 List cells’ types and hormones secreted from the pituitary gland.
a.i.14 Describe structure, synthesis, secretion, transport and metabolism of:
a. Thyroid hormones.
b. Adrenal steroids.
c. Insulin
d. Glucagon
a.i.15 Recognize physiological actions of the following hormones:
a. Growth hormone
b. Thyroid hormones
c. Parathyroid hormones
d. Adrenal steroids.
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
e. Prolactin
f. Insulin
g. Glucagon.
h. ADH
i. Oxytocin
a.i.16 List types and functions of somatomedines.
a.i. 17 Describe control of secretion of the following hormomes:
a. Growth hormone.
b. Thyroid hormones.
c. Cortisol.
d. Aldosterone.
e. Parathyroid hormones.
f. ADH.
a.i.18 Identify stages of growth.
a.i.19 List hormones affecting growth.
a.i.20 State causes of disturbed growth.
a.i.21 Define permissive action and name examples.
a.i.22 Recognize hormones controlling glucose homeostasis.
a.i.23 List types and effects of tumours affecting.
a. Pituitary.
b. Thyroid.
c. Adrenal cortex
d. Adrenal medulla.
e. Mammary gland.
a.i.24 Describe non-neoplastic breast lesions.
a.i.25 Define carcinoma in situ.
a.i.26 State prognosis of breast cancers.
a.i.27 Describe morphology of:
a. Pheochromocytoma.
b. Neuroblastoma.
c. Islet cell tumours.
a.i.28 List causes and effects of hpo and hyper function of the following glands.
a. Pituiotary gland.
b. Thyroid gland.
c. Parathyroid glands
d. Adrenal cortex.
a.i.29 Describe pathogenesis of
a. Goiter
b. Grave's disease
c. Diabetes insipidus.
d. Diabetes mellitus.
a.i.30 List types of thyroiditis.
a.i.31 Describe the diagnosis of pheochromocytoma.
a.i.32 Describe the tests used to assess the functions of the following endocrine glands:
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
a. Pituitary function tests.
b. Thyroid function tests.
c. Adrenal cortex.
d. Endocrine pancreas.
a.i.33 Write the different preparations of:
a. Thyroid hormones.
b. Natural and synthetic steroids.
c. Insulin hormone.
a.i.34 Name different oral hypoglycaemic drugs.
a.i.35 List the mechanism of actions, pharmacologic actions, therapeutic uses, and adverse
effects of:
a. Thyroid hormones.
b. Antithyroid drugs.
c. Glucocorticoids.
d. Mineralocorticoids.
e. Cortisol antagonists.
Oral hypoglycaemic drugs
(ii) Teaching strategies to be used to develop that knowledge:
a.ii.1 Introductory lecture gives an overview of the content and significance of the
course and of its relationship to students’ existing knowledge.
a.ii.2 Each subsequent lecture will start by the illustration of a clinical case or
problem followed by short discussion on this case.
a.ii.3 The tutor will then overview particular content in relation to the syllabus.
(iii)Methods of assessment of knowledge acquired:
a.iii.1 Mid-module quiz, MCQs which carry 20% of final assessment.
a.iii.2 End of module exam (Two Hours) MCQs which carry 50% of final assessment
b. Cognitive Skills
(i) Description of cognitive skills to be developed:
The student will be exposed to several interactive clinical cases applied to the given
knowledge in order to acquire the ability to:
b.i.1 Differentiate between morphology of various disease processes.
b.i.2 Correlate the disease process to medical knowledge, gross features and microscopic
features.
b.i.3 Correlate the pituitary cell types with the hormones secreted
b.i.4 Correlate pathological changes related to pituitary adenomas to their clinical effects
b.i.5 Interpret laboratory information with regard to suspected thyroid disorders
b.i.6 Analyze the mechanisms controlling thyroid hormones secretion
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
b.i.7 Interpret the Physiological basis of goiter
b.i.8 Correlate the pathogenesis of hyperparathyroidism on bone, kidneys, and
morphologic changes in these systems.
b.i.9 Evaluate adrenocortical function in response to serum cortisol, serum
aldosterone
b.i.10 Differentiate between normal histology of anterior pituitary and
microscopic features of pituitary adenomas.
b.i.11 Correlate morphology of pituitary adenomas with clinical effects
b.i.12 Differentiate morphologically between benign and malignant thyroid lesions.
b.i.13 Differentiate anatomically and physiologically between the 3 zones of cortex and their
cellular arrangement
b.i.14 Differentiate morphologically between benign and malignant neoplasms of
the breast.
b.i.15 Analyze role of the hypothalamus in neuro-endocrine communication
b.i.16 Correlate the pathogenesis to morphologic findings in different systems (kidney, retina,
nerves) and hence the clinical presentation.
b.i.17 Assess the prognosis of diabetes mellitus based on the evaluation of pathology seen in
various organs
b.i.18 Tabulate the differnces between prostacyclins and thromboxanes
b.i.19 Evaluate the importance of antidiabetic therapy to control blood glucose level
b.i.20 Analyse the results of laboratory findings of thyroid and parathyroid dysfunction
b.i.21 Correlate biochemical findings of parathyroid dysfunction to treatment strategy of the
case.
b.i.22 Design a suitable drug regimen to control Type I diabetic patients
b.i.23 Relate pathological changes in diabetes to biochemical changes
(ii) Teaching strategies to be used to develop these cognitive skills:
b.ii.1;Tutorials:
 Case based interactive tutorials and SDL sessions, where students are divided into small
group and cases allocated in advance to be researched by students and discussed
during the sessions to develop interpretation, integration and discussion skills, as well
as to encourage the use of IT
 The students are divided into two main groups
 Each group of students is further subdivided into smaller subgroups.
 Each subgroup is assigned an interactive case based on the objectives.
 Members of each subgroup are encouraged to:
1- Discuss the subject within their group in the classroom based on their readings from the
book, lectures and practical session.
2- Tabulate differences between variable disease processes
3- Questions are encouraged among all the students guided by the tutor.
b.ii.2; Practical sessions:
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Faculty of Medicine- King Abdul Aziz University
 Illustrations are given to the student in the form of digital images, gross
specimen and histological sections
b.ii.3; Clinical presentations
 The students will be sub-classified into small groups.
 Members of the small group are encouraged to;
a. Examine the patients,
b. Identify the abnormality in the slides.
c. Describe the condition
d. Formulate Differential diagnosis
Correlate the disease process to medical knowledge.
(iii)Methods of assessment of student's cognitive skills:
b.iii.1 Mid module quiz
b.iii.2 End of module exam
b.iii.3 OSPE exam; carry 15% of final assessment
 Including 10 stations; 7 for laboratory work, 3 for Assessment of reasoning skills and
problem solving skills.
 The student will take 3 minutes in each station.
c. Interpersonal Skills and Responsibility
(i)
Description of the interpersonal skills and capacity to carry responsibility to be
developed :
By the end of the course the student will gain the ability and carry responsibility to:
c.i.1 Acquire the skill of self learning.
c.i.2 Communicate with Peers.
c.i.3 Built up personal responsibility.
c.i.4 Acquire the skill of team work.
c.i.5 Acquire the skill of respect to colleagues.
(ii)
Teaching strategies to be used to develop these skills and abilities:
c.ii.1 PBL.
c.ii.2 Tutorial sessions
(iii)
Methods of assessment of students interpersonal skills and capacity to carry
Responsibility:
c.iii.1 Class attendance is recorded.
c.iii.2 Score for performance during PBL session using a special form
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
d. Communication, Information Technology and Numerical Skills
(i) Description of the skills to be developed in this domain:
d.i.1 To gain the experience of gathering authorized, reliable medical information, from
medical web sites
d.i.2 To gain the experience of using CD & E- textbooks and other medical software that
support diagnosis, & interpretation of lab results & optimal pharmacotherapy.
d.i.3 Develop the skill of choosing the appropriate key words suit the searching material
(ii) Teaching strategies to be used to develop these skills:
d.ii.1 Clinical cases
d.ii.2 Problem based learning
(iii) Methods of assessment of students numerical and communication skills :
d.iii.1 PBL.
e. Psychomotor Skills
(i) Description of the psychomotor skills to be developed and the level of performance
required:
By the end of the course, students should he able to:
e.i.1 Interpret Microscopic and macroscopic images of the endocrine glands
e.i.2 Interpret the reports of the thyroid scan
e.i.3 Identify the pathological changes in the endocrine diseases
(ii) Teaching strategies to be used to develop these skills:
e.ii.1 Practical sessions
(iii) Methods of assessment of students psychomotor skills:
e.iii.1OSPE
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
5. Schedule of Assessment Tasks for Students During the Semester
Assessment
1
2
3
4
Assessment task
Mid term quiz
Final exam
OSPE exam
PBL
Week due
2nd week
3rd week
3rd week
2nd and 3rd weeks
Proportion of Final Assessment
20%
50%
15%
15 %
D. Student Support
1. Arrangements for availability of faculty members for individual student consultations and
academic advice.
 Each teaching staff has to be available for the students for 2hours for 3 days a
week.
 There will be a schedule for office hours of each staff declared to the students.
 Contact numbers, pagers and mobile numbers are available to the students.
 Office hours are held in both faculty’s offices or hospital‘s offices of staff members.
E. Learning Resources
1-Required Text:
 Robbins Basic Pathology, 8th Edition (2007) By: Kumar, Abbas, Fausto, Michel.
 Grant J. C.B.: Grant Anatomy, 10th edition, Lippincott, William and Wilkins.
 Ganong, Review of Medical
Physiology, 20th edition,
 Katsung, Basic and Clinical Pharmacology
2- Recommended Books and Reference Material :
 Robbins and Cotran Pathologic Basis of diseases, 7th Edition (2005),By: Kumar, Abbas,Fausto,
 Robin Reid, Fiona Roberts. Pathology Illustrated. 6th Ed, Elsevier, Churchill Livingston. 2005.
 Ivan Damjanov. Pathology secrets. 2nd ed. Elsevier Mosby.2005
 Sadler TW. Langman’s Medical Embryology, 10th edition. Lippincott, William and Wilkins
D. R. Laurance & P. N. Bennett, Clinical pharmacology.
3-.Electronic Materials, Web Sites etc:
www.studentconsult.com
www.Robbinspathology.com
www.Library.med.utah.edu/WebPath.com
4- Other learning material such as computer-based programs/CD, professional
standards/regulations: NOT APPLICABLE
Quality & Academic Accreditation Unit
Faculty of Medicine- King Abdul Aziz University
F. Facilities Required
Indicate requirements for the course including size of classrooms and laboratories (ie number
of seats in classrooms and laboratories, extent of computer access etc.)
1. Accommodation (Lecture rooms, laboratories, etc.)
 Lecture rooms are available.
 in pathology department, laboratory rooms can accomodate at most 60 students at a time,
they are provided by viewrs, data show, computers and ten-headed microscope, and 50
mono-headed microscopes.
 Tutorial rooms with data show and computers are available
 Tutorial rooms should be provided by rounded tables.
Computers, data show and microphones are not all the time working in lecture rooms
particularly in the early morning
2.Computing resources
 Maintenance of computers is little bit deficient in the female section
 There should be an active IT department on female section.
3.Other resources
 Pathology laboratory and museum needs the presence of more representative gross
specimens
 Gross specimens have to prepared in the plastinization process to be easy-handled, clean
and to avoid pollution caused by formaline solution
Trained personal that have experience in handling and processing of gross specimen jars are
highly needed
G.
Course Evaluation and Improvement Processes
1. Strategies for Obtaining Student Feedback on Effectiveness of Teaching
 Confidential completion of standard course evaluation questionnaire
 Confidential completion of course objectives’ evaluation questionnaire
Frequent meetings of the module committee with 3rd year leaders
2. Other Strategies for Evaluation of Teaching by the Instructor or by the Department
Confidential completion of standard course evaluation questionnaire by the faculty.
3. Processes for Improvement of Teaching
Tutors are encouraged to attend workshops offered by the medical education department
4. Processes for Verifying Standards of Student Achievement (eg. check marking by an
independent member teaching staff of a sample of student work, periodic exchange and
remarking of tests or a sample of assignments with staff at another institution)
5 .Describe the planning arrangements for periodically reviewing course effectiveness and
planning for improvement.