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Mrs. Young has chest pain Mrs. Young is a 35 year old woman admitted to the hospital to determine the cause of her complaint of vague chest pains in stressful situations. Studies carried out at another hospital two years ago had included a chest x-ray which revealed right ventricular enlargement. A moderate systolic murmur and a split second heart sound were found at that time. 1. List the possible causes of a systolic murmur. 2. What is a split second heart sound and what can cause it to appear? Based on the initial findings, Mrs. Young underwent cardiac catheterization. The following data was obtained. MEASUREMENT Heart rate Ventilation O2 consumption [Hemoglobin] O2 content – mixed venous blood O2 content – pulmonary artery RESULTS 85/min 5.46 L/min 219 ml/min 13.4 gm/dL 13.14 ml/dL O2 content – pulmonary vein 17.78 ml/dL O2 content - aorta 17.78 ml/dL 16.31 ml/dL 3. Examine the data above and decide whether any of it is abnormal and requires explanation. 4. What pathology must be present in Mrs. Young’s cardiovascular system to result in the data seen above? 5. We know that Mrs. Young has a shunt from the left to the right side of the cardiovascular system. What are possible locations for this shunt? 6. How would you determine which of the possibilities is actually present? The following pressures were recorded during Mrs. Young’s cardiac catheterization. MEASUREMENT Right atrium (mean) Right ventricle (systolic/diastolic/end diastolic) Pulmonary artery (systolic/diastolic/mean) Left atrium (mean) Left ventricle (systolic/diastolic/end diastolic) Aorta (systolic/diastolic/mean) RESULTS (mm Hg) 6 30/2/8 30/6/14 6 106/-3/10 102/66/84 7. Using this data determine the location of Mrs. Young’s shunt.