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1-Carbamazepine is used for: abcd- AV block Porphyria Absence sizure Tonic-clonic seizures 2- competitive flenzodiazepine receptor antagonist is: abcd- Beta-carbolinen derivatives Flumunocrial Zalephon Ramelteon 3- which of the following is a gas anaesthetic? abcd- Halothane Isoflurane Nitrous oxide Desfluraine 4- which of the following antidepressants is a selective serotonin reuptake inhibitor: abcd- Phenelzine Desipramine Mapcotiline Fluoxetine 5-the drug of choice for manic-depressive psychosis is: abcd- Imipramice Chlordiazepoxide Isocarboxazid Lithium carbonate 6-non-steroidal anti-inflammatory drugs are not taken with lithium because: abcd- Causes serotonin syndrome Decreases serum lithium level Decrease renal elimination of lithium Induce hypothyroidism 7- dopamine receptor agonist is: abcd- Selegline Amantadine Bromocriptine Benzatrpine 8- Contraindication for neuroleptics includes: abcd- Tourette’s syndrome Parkinsons disease Huntingtons disease Pruritus 9- Adverse effects of lithium includes: abcd- Sinus tachycardia Tremor Hyperthyroidism Weight loss 10- A CSF serum albumin index of more than 9 refers to: abcd- Increased permeability of blood brain barrier Multiple sclerosis Dural tear Hepatic encephalopathy 11-Night blindness: abcd- Occurs due to affection of cons of retina Is characterized by corneal ulceration Is treated by retinol medications Is due to deficiency of vitamin A receptors 12- Gaucher disease is due to deficiency of abcd- Sphingomyelinase Glucocerbrosidase Galactocrbrosidase B-galactosidase 13- the most abundant shphingophospholipid is: abcd- Ganglioisdes Cerebrosides Ceramide Sphingomyelin 14- the neuronal cell death occurring with blood sugar level below 18 directly explained by: abcd- Diminished ATP production Depletion of metabolism intermediates of TCA cycle Decreased synthesis of neurotransmitters Glutamate excitotoxicity 15- In CNS, astrocytes role is to: abcd- Synthesize glutamate neurotransmitters Uptake glutamate released during neurotransmission Deamination of glutamine Mediate neurological actions of glutamate 16- withdrawal refle is a type of: abcd- Superficial reflex Polysynaptic reflex Autonomic reflex Visceral reflex 17- which of the following is a clinical feature of parkinson’s disease? abcd- Intentional tremors Mask face Pendular knee jerk Positive babinski’s sign 18- the vermis of the cerebellum controls: abcd- Motion of distal limbs, especially hands and feet Axial movements of neck, shoulder and hip Sequence of movements Timing and coordination of movements 19- A lesion in the hippocampus produces: abcd- Autonomic dysfunctions Anterograde amnesia Aggressive behaviour Personality changes 20-normal function of broca’s area of the cerebral cortex is : abcd- Word formation Understanding of words Thinking Mathematical calculation 21- in heat stroke there is: abcd- Increased sweating all the time Slow rise in temperature Failure of thermo-regulation Little change in core temperature 22-Rapid Eye movement (REM) sleep is called: abcd- Paradoxical sleep Slow wave sleep Abnormal sleep Light sleep 23- Transduction of olfactory stimuli in olfactory receptors occurs by? abcd- Activation of adenyl cyclase Hyperpolarizing potential in the receptors Activation of tyrosine kinase Activation of phospholipase C 24-DRAWING OF LESION AT OPTIC CHIASM If the lesion occurs in the visual field at optic chiasma what visual defect may occur? abcd- 25- A 22 year old patient sees his ophthalmologist because it is becoming increasingly difficult for him to read the newspaper. His vision problem likely results from an inability to contract which of the following? abcd- The iris The ciliary muscles The extraocular muscles The pupil 26- Maximum refraction of light rays takes place at the: abcd- Vereous humor Cornea Aqueous humor Lens 27- high frequency sounds produce: abcd- Stronger vibration of the vestibular membrane Multiple action potential in the auditory nerve Lesser movements of the middle ear bones Vibrations of the basilar membrane near the base of cochlea 28- sensorineural deafness is caused by: abcd- Rupture of the tympanic membrane Damage to the inner hair cells Otosclerosis (fusion of bony ossicles) Damage to parietal lobes of the brain 29- the taste buds stimulated by sour substances are mainly located at: abcd- Tip of tongue Dorsum of tongue Edge (side) of tongue Back of tongue 30- the most common cause of acute bacterial meningitisin adult is: abcd- Neisseria meningitides Haemophilus influenza Streptococcus pneumonia Naegleria fowleri 31- which one of the following would be finding of CSF examinationin bacterial meningitis: abcd- Lymphocyte count elevation, and decreased glucose concentration Neutrophil count elevation, and increased glucose concentration Lymphocyte count elevation, and increased glucose concentration Neutrophil count elevation, and decreased glucose concentration 32- acute haemorrhagic conjunctivitis is caused by : abcd- Adenovirus Chlamydia trachomatis Coxsackievirus A24 Herpes simplex virus 33- the most common bacterial pathogen causing otitis media: abcd- Staphylococcus aureus Pseudomonas aeruglinosa Streptococcus pneumonia Neisseria meningitides 34-the most common causative agent of chronic brain abscess is? a- Staphylococcus aureus b- Mycobacterium tuberculosis c- Group A streptococci d- Neisseria meningitides 35- Healing of brain infarction occur by: abcd- Regeneration Gliosis Metaplastic changes Both regenartion and fibrosis 36- gross microscopic changes which associate bain infarction start within abcd- Three hours Six hours Twelve hours Twenty four hours 37- mycotic aneurysms is caused by: abcd- Inflammation of blood vessels Congenital weakness of blood vessel wall Atherosclerosis Hypertension 38- pyaemic brain abscesses occurs usually due to: abcd- Direct spread from adjacent suppurative sinusitis Direct inoculation of the organism after compound fracture of sk Hematogenous spread from suppurative heart disease Lymphatic spread from a nearby suppurative lesion 39- pyogenic brain abscess could be complicated by: abcd- Meningitis Malignant transformation Sinus tract formation Fistula formation 40- Neurofibrillary tangles are diagnostic for: abcd- Alzheimer disease Parkinsonism Multiple sclerosis Astrocytoma 41- the gross pathologic finding in parkinsonism is: abcd- Congestion of the cerebral cortex Thrombosis of cerebral vessels Pallor of substantia nigra Multiple cerebral infarcts 42- most of the CNS tumors in children arise in: abcd- Frontal lobes Temporal lobes Anterior fossa Posterior fossa 43- most common location of ependymoma in adult is: abcd- Spinal cord Fourth ventricle Third ventricle Above tentorium 44- the nerve that passes through the foramen rotundum is? abcd- Frontal Maxillary Ophthalmic Mandibular 45- typical cervical vertebra has a abcd- Thick body Bifid spine Costal facet Odontoid process 46- the best place to do lumbar puncture is: abcd- Between T12 and L1 Between L1 and L2 Between L2 and L3 Between L3 and L4 47- The brachial plexus arises from the spinal nerve roots of: abcd- C5-T1 C3-T1 C3-C7 C4-C7 48- the following tract ascends on the same side of the spinal: abcd- Gracile tract Lateral spinothalamic tract Ventral spinothalamic tract Ventral spinocerebellar tract 49- Lateral corticospinal tract decussates in the: abcd- Medulla oblongata Pons Tegmentum Spinal cord 50- degeneration of the substantia nigra will lead to: abcd- Paralysis of laryngeal and pharyngeal muscle Paralysis of limb muscle Incoordination of muscle movements Upper motor neuron lesion 51- largest cerebellar nucleus is: abcd- Globose Dentate Emboliform Fastigial 52- which of the following is a key factor of the function of the basal ganglia: abcd- Thalamus Subthalamus Hypothalamus Epithalamus 53- retrolenticular part of the internal capsule is mainly concerned with: abcd- Visual function Auditory function General sensation Motor function 54- which of the following is considered part of the limbic system? abcd- Pulvinar Caudate nucleus Anterior nucleus of the thalamus Septal nucleus of the hypothalamus 55- which of the following hypothalamic nuclei controls the circadian rhythem? abcd- Lateral Dorsomedial Posterior Suprachiamatic 56- pontine arteries are branches of the: abcd- Internal carotid Vertebral Basilar Anterior cerebral 57- the floor of inferior horn of lateral ventricle of the brain is related to: abcd- Amygdaloid nucleus Hippocampus Hypothalamus Parahippocampal gyrus 58- the key cell in the olfactory pathway is: abcd- Bipolar cell Granular cell Tufted cell Mitral cell 59- transection of occulomotor nerve will lead to: abcd- Constriction of the pupil Decrease secretion of tears Inability to move the eye laterally Inability to close the eye 60- which one of the following muscles is supplied by the trigeminal nerve? abcd- Tensor tympani Stapedius Posterior belly of digastric Buccinators 61- the developmental anomaly in which the vertebral arch is absent, the spinal cord and meninges are outside the vertebral canal is described as: abcd- Spina bifida occulta Spina bifida cystica with meningocele Spina bifida with meningomyelocele Spinabifida with myelschisis 62- which of the following is the motor nucleus of the vagus nerve? abcd- Nucleus solitaries Dorsal nucleus of vagus Inferior salivatory nucleus Nucleus ambiguous 63- postganglionic fibers from otic ganglion supply: abcd- Parotid gland Lacrimal gland Carotid body and sinus Tympanic membrane 64- which one of the following nerves carries parasympathetic fibers of the facial nerve? abcd- Chorda tympani nerve Greater petrosal nerve Lesser petrosal nerve Deep petrosal nerve 65- which of the following eye structures is mesodermal in origin? abcd- The lens Retina Sclera Eye lids