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Transcript
Team: Narwhals Cried
Jeff Jensen
Todd Cooke
Marcia Shofner
Meagan Snodgrass
Caroline Breitenberger
Stephen Chordas III
Steven Kalinowski
LysenkoChem
Facilitated by: Mary Pat Wenderoth, Xueqing Liu
Setting

nd
2
semester of introductory
biology for majors
 1st semester topics: genetics,
molecular and cell biology
 Last week: introduction to
natural selection
 Persistent misconceptions
Pre and post assessment
Questions from the Concept Inventory of Natural
Selection focusing on alternative Lamarckian vs.
Darwinian explanations of evolutionary scenarios.
On-line assessment
Just-in-time pre-test
Summative assessment post-test
2004 revision of original CINS presented in: Anderson, D.L., Fisher, K.M., & Norman, G.J.
(2002). Development and evaluation of the conceptual inventory of natural selection.
Journal of Research in Science Teaching, 39, 952-978. (questions 6,7,17,19)
Objectives of today’s activities
 Distinguish between acquired and
heritable traits
 Describe the role of inheritance in
evolution
 Evaluate the implications of
evolutionary thinking for human
medicine
Now the professor will start …
Learning goals
 Significance of evolution in your life
 Mechanisms of natural selection
Human
Immunodeficiency
Virus (HIV)
Adult prevalence rate
http://www.compassion.com/about/AIDS/default.htm
http://www.springwidgets.com/widgets/view/13013
Scenario
The Gates Foundation has asked you to
serve on a committee to review a grant
proposal by Dr. K. Cramal of the Lysenko
Chem Institute.
Every 14 seconds a
child is orphaned by
HIV
LysenkoChem
LysenkoChem
Traxoline ®
LysenkoChem
Traxoline® mode of action
HIV-specific immune enhancer
o Current level of HIV resistance in the
human population is low
o Traxoline® strengthens this resistance level
LysenkoChem
Protocol
o Each generation will receive a dose by
their 5th birthday
o Doses administered for three generations
Predicted HIV resistance after
Traxoline® treatments
LysenkoChem
4th (Complete)
Human Resistance to HIV
100%
3rd
70%
2nd
40%
Current
1st
0%
Generations
Evaluate the proposal to the Gates Foundation
from the perspective of an evolutionary
biologist.
This proposal is :
A. Not enough information
B. Scientifically sound
C. Scientifically unsound
Now, in your group…
discuss the proposal to the Gates Foundation
from the perspective of an evolutionary
biologist.
This proposal is :
A. Not enough information
B. Scientifically sound
C. Scientifically unsound
Remember the premises of
natural selection
Brainstorming
Now, in your group…
 Propose 2 examples of human traits
that would not be inherited
Propose 2 examples of human traits
that would be inherited
What have we learned?
Human Resistance to HIV
4th (Complete)
100%
3rd
70%
2nd
40%
Current
1st
0%
Generations
What have we learned?
Acquired
traits are
NOT
inherited!
 Don’t forget to do your on-line post test
before the next class
Lizards, Canary Islands
The Canary Islands are seven islands just west of
the African continent. The islands gradually
became colonized with life: plants, lizards, birds,
etc. Three different species of lizards found on the
islands are similar to one species found on the
African continent (Thorpe & Brown, 1989).
Because of this, scientists assume that the lizards
traveled from Africa to the Canary Islands by
floating on tree trunks washed out to sea.
Clicker Question 1
Which statement best describes how traits in lizards will be
inherited by offspring?
A. When parent lizards learn to catch particular insects, their
offspring can inherit their specific insect-catching-skills.
B. When parent lizards develop stronger claws through
repeated use in catching prey, their offspring can inherit
their stronger-claw trait.
C. When parent lizards’ claws are underdeveloped because
easy food sources are available, their offspring can inherit
their weakened claws.
D. When a parent lizard is born with an extra finger on its
claws, its offspring can inherit sixfingered claws.
Clicker Question 2
What do you think happens among the lizards of a certain
species when the food supply is limited?
A. The lizards cooperate to find food and share what they
find.
B. The lizards fight for the available food and the
strongest lizards kill the weaker ones.
C. Genetic changes that would allow lizards to eat new
food sources are likely to be induced.
D.The lizards least successful in the competition for food
are likely to die of starvation and malnutrition.
Galapagos finches
Scientists have long believed that the 14 species of
finches on the Galapagos Islands evolved from a single
species of finch that migrated to the islands one to five
million years ago (Lack, 1940). Recent DNA analyses
support the conclusion that all of the Galapagos
finches evolved from the warbler finch (Grant, Grant &
Petren, 2001; Petren, Grant & Grant, 1999). Different
species live on different islands. For example, the
medium ground finch and the cactus finch live on one
island. The large cactus finch occupies another island.
One of the major changes in the finches is in their
beak sizes and shapes as shown in this figure.
Clicker Question 1
What type of genetic variation in finches is passed to the
offspring?
A. Any behaviors that were learned during a finch’s lifetime.
B. Only characteristics that were beneficial during a finch’s
lifetime.
C. All characteristics that were genetically determined.
D.Any characteristics that were positively influenced by the
environment during a finch’s lifetime.
Clicker Question 2
In the finch population, what are the primary
changes that occur gradually over time?
A.The traits of each finch within a population
gradually change.
B.The proportions of finches having different
traits within a population change.
C. Mutations occur to meet the needs of the
finches as the environment changes.
Where did HIV come from?
Questions ???