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Common Childhood Infectious Diseases DR. FAHAD AL ZAMIL Associate Professor & Consultant Pediatric Infectious Diseases King Khalid University Hospital King Saud University, Riyadh Skimmia Japonica Rubella Measles RNA Virus Incubation Period: 8 – 12 days Clinical Features Complications Treatment Isolation & Infectivity: 2 days before till 5 days after rash Vaccine Measles (cont.) Koplik’s spots Measles (Cont.) Measles vs. Scarlet fever Mumps RNA Virus Incubation Period: 14 – 21 days Clinical Features Complications Treatment Isolation & Infectivity: 9 days after onset of parotid swelling Vaccine Rubella RNA Virus Incubation Period: 14 – 21 days Clinical Features Complications Treatment Isolation & Infectivity: 7 days from onset of rash Congenital Rubella: until 1 year of age Vaccine Rubella (Cont.) Rubella, Smallpox, Chickenpox Congenital Rubella Syndrome Chicken Pox (Varicella) DNA Virus Incubation Period: 10 – 21 days Clinical Features Complications Treatment Isolation & Infectivity: 2 days before rash till all skin lesions have crusted (6th day of rash) Vaccine Cont. Chicken Pox Cont. Chicken Pox Diphtheria Corynebacterium diphtheriae Incubation Period: 2 – 7 days Clinical Features Complications Treatment Isolation & Infectivity: up to 6 weeks, but with treatment communicable for fewer than 4 days Vaccine Diphtheria (Cont.) Pertusis (Whooping Cough) Bordetella Pertusis Incubation Period: 7 – 14 days Clinical Features Complications Treatment Isolation & Infectivity: up to 6 weeks, but with treatment => 5 days after starting therapy Vaccine Whooping Cough Video: Whooping Cough: Child Video: Whooping Cough: Infant Tetanus Clostridium tetani Incubation Period: 2 days to months, most within 14 days Clinical Features Complications Treatment Isolation: no person to person transmission Vaccines Haemophilus influenzae type b (Hib) Clinical Features Complications Treatment Isolation & Infectivity: droplet precautions for 24 hours after starting antimicrobial therapy Vaccine Cerebrospinal fluid culture positive for Hib (Gram stain) Hib (Cont.) Poliovirus Incubation Period: 7 – 21 days Clinical Features Complications Treatment Isolation & Infectivity: several weeks Vaccines: Polio Vaccines IPV OPV Thrush Candida Albicans Clinical Features Complications Treatment Croup Parainfluenza Incubation Period: 2 – 6 days Clinical Features Complications Treatment Isolation & Infectivity: contact precaution in hospital, infective up to 3 weeks Video: A Child with Croup Bronchiolitis Respiratory Syncytial Virus Incubation Period: 2 – 8 days Clinical Features Complications Treatment Isolation & Infectivity: 3 – 8 days (up to 4 weeks in infants) Erythema Infectiosum (Fifth Disease) Parvovirus B19 Incubation Period: 4 – 21 days Clinical Features Complications Treatment Isolation & Infectivity: droplet precautions for 7 days Roseola (Sixth Disease) HHV-6 Incubation Period: 9 – 10 days Clinical Features Complications Treatment Viral Hepatitis Feature Hepatitis A Hepatitis B Hepatitis C Hepatitis D Hepatitis E Virus HAV HBV HCV HDV HEV Genome RNA DNA RNA RNA RNA 15-50 days 45-160 days 7-9 weeks 2-8 weeks 15-60 days Onset Acute Insidious Insidious Acute Acute Transmission Oral Parenteral Perinatal Parenteral Parenteral Oral Yes Yes Incubation Sequelae: Fulminant liver failure Carrier Chronic hepatitis Mortality Rare Uncommon Uncommon No No Yes Yes Yes Yes Yes Yes No No 0.1-0.2 % 0.5-2 % 1-2 % 2-20 % 1-2 % Infectious Mononucleosis Epstein-Barr Virus Incubation Period: 30 – 50 days Clinical Features Complications Treatment Isolation & Infectivity: patients with recent infection should not donate blood Further Reading