Download CHEM 210 - Winona State University

WINONA STATE UNIVERSITY
PROPOSAL FOR NEW COURSES
Department ___Chemistry_______________________________________
Date ____9/13/04_______________
___210_______________
Course No.
____Allied Health Chemistry___________________________________ ___5 SH________
Course Name
Credits
This proposal is for a(n)
__XX__ Undergraduate Course
______ Graduate Course
Applies to:
______ Major
_____ Required
_____ Elective
Prerequisites
__High school chemistry or CHEM 108 and MATH 100 or qualifying score on mathematics placement exam.
Grading method __XX__ Grade only
______ Minor
_____ Required
_____ Elective
______ P/NC only
______ University Studies*
______ Grade and P/NC Option
Frequency of offering _fall, spring_____________________
*For University Studies Program course approval, the form Proposal for University Studies Courses must also be completed. submitted
according to the instructions on that form.
Provide the following information (attach materials to this proposal):
A.
Course Description
1.
2.
3.
4.
5.
6.
B.
Rationale
1.
2.
3.
C.
Statement of the major focus and objectives of the course.
Specify how this new course contributes to the departmental curriculum.
Indicate any course(s) which may be dropped if this course is approved.
Impact of this Course on other Departments, Programs, Majors, or Minors
1.
2.
D.
Catalog description.
Course outline of the major topics and subtopics (minimum of two-level outline).
Basic instructional plan and methods.
Course requirements (papers, lab work, projects, etc.) and means of evaluation.
Course materials (textbook(s), articles, etc.).
List of references.
Does this course increase or decrease the total credits required by a major or minor of any other department? If so, which
department(s)?
List the departments, if any, which have been consulted about this proposal.
University Studies Course Proposals
The form Proposal for University Studies Course must also be completed and submitted according to the instructions on that form.
Attach a Financial and Staffing Data Sheet.
Attach an Approval Form.
Department Contact Person for this Proposal:
______________________________________________
Name (please print)
A. Course Description
________________
Phone
_______________________________
e-mail address
1.
Catalog description
A study of the principles of general, organic, and biological chemistry with emphasis on the numerous
connections between chemistry and human health. Four lectures and one laboratory period per week.
Prerequisites: high school chemistry or CHEM 108 and MATH 100 or qualifying score on mathematics
placement exam.
2.
Course outline
Topic (Approximate number of lecture periods)
Measurements (1)
A. Physical Quantities
a. Mass
b. Length
c. Volume
B. Scientific Expression
a. Notation
b. Significant Figures
Composition and Structure of Atoms, Elements and the Periodic Table (2)
A. Elements and Atomic Number
B. Iostopes and Atomic Weight
C. Periodic Table
a. Electronic Structure
b. Electron Configurations
Nuclear Chemistry (1)
A. Isotopes
B. Nuclear Reactions
a. Decay
b. Half-life
C. Medical Uses
Structure and Properties of Ionic and Covalent Bonds (2)
A. Periodic Properties
a. Ion Formation
i. Octet Rule
ii. Electron-Dot Symbols
b. Molecular Compounds
B. Ionic Bonds
a. Biologically Important Ions
b. Intro to Acid and Base Chemistry
C. Covalent Bonds
a. Molecular Structure
b. Electronegativity and Polarity
Calculations of Chemical Reactions and Equations (2)
A. Chemical Equations
a. Balancing
b. Avogadro’s Number and the Mole
i. Stoichiometric Relationships
ii. Conversions
c. Carbon Monoxide Poisoning
B. Equation Calculations
a. Conversions
b. Theoretical and Percent Yield
States of Matter- Gases, Liquids, and Solids (2)
A. Gases
a. Combined Gas Law
i. Boyle’s Law
1. Blood Pressure
ii. Charles’s Law
iii. Gay-Lussac’s Law
b. Ideal Gas Law
B. Liquids
C. Solids
Chemical and Physical Change/ Energy, Rate and Equilibrium (2)
A. Heat Changes in Reactions
a. Exothermic Reactions
b. Endothermic Reactions
c. Free Energy
B. Reaction Rates
a. Catalysts
b. Concentration
c. Temperature
C. Equilibrium
a. Le Châtelier’s Principle
Reactions and Solutions (2)
A. Classes of Reactions
a. Precipitation
b. Acid/Base and Neutralization
c. Oxidizing
B. Properties of Solutions
a. Liquids
b. Gases
i. Henry’s Law
C. Concentrations
a. Percentages
i. Weight/Volume
ii. Weight/Weight
b. Solutions
i. Molarity
ii. Dilution
D. Concentration-Dependent Properties
a. Vapor Pressure
b. Freezing Point Depression/Boiling Point Elevation
c. Osmotic Pressure
d. Oral Rehydration Therapy
Acid-Base/ Oxidation-Reduction (2)
A. Brønsted-Lowry Theory
B. Conjugate Acids and Bases
a. Strength
b. Dissociation in Water
i. pH
1. measuring
2. calculating
b. Reactions
C. Buffers
a. Preparation
b. Henderson-Hasselbalch equation
D. Oxidation and Reduction Processes
Alkanes, Haloalkanes (3)
A. Structure and Physical Properties
a. Hybridization
b. Isomers
c. Nomenclature
B. Cycloalkanes
a. Nomenclature
b. Isomers
C. Reactions
D. Haloalkanes
Alkenes, Aromatics, Alkynes (3)
A. Alkenes
a. Structure and Properties
i. Hybridization
ii. Isomers
iii. Nomenclature
b. Reactions
i. Addition
1. Hydrogenation
ii.
2. Halogenation
Markovnikov’s Rule
1. Hydration
2. Hydrohalogenation
iv.
B. Aromatics
a. Structure and Properties
b. Nomenclature
c. Reactions
C. Alkynes
a. Structure and Properties
i. Hybridization
Alcohols, Ethers, Thiols (2)
A. Alcohols
a. Structure and Properties
i. Nomenclature
ii. Classification
b. Reactions
i. Preparation
ii. Oxidation
iii. Dehydation
c. Medically-Important Alcohols
B. Phenols
C. Ethers
D. Thiols
a. Reactions
i. Oxidation
ii. Reduction
Carbohydrates (4)
A. Types of Carbohydrates
a. Monosaccharides
i. Structure and Physical Properties
ii. Stereoisomers
1. Optical Activity
2. Fischer Projections
3. D,L system
b. Disaccharides
i. Structure and Physical Properties
ii. Biologically-Important
1. Linkages
2. Digestion
iii. Blood Group Antigens
c. Polysaccharides
i. Biologically-Important
Aldehydes, Ketones (2)
A. Aldehydes
a. Structure and Physical Properties
b. Nomenclature
c. Reactions
i. Preparation
ii. Reduction
B. Ketones
a. Structure and Physical Properties
b. Nomenclature
c. Reactions
i. Preparation
ii. Reduction
iii. Keto-Enol Tautomerism
iv. Aldol Condensation
Carboxylic Acids, Amines, and Carboxylic Acid Derivatives (4)
A. Carboxylic Acids
a. Structure and Physical Properties
b.
c.
B. Esters
a.
b.
c.
Nomenclature
Reactions
i. Preparation
ii. Reduction
iii. Esterification
Structure and Physical Properties
Nomenclature
Reactions
i. Preparation
ii. Hydrolysis
iii. Saponifcation
d. Phosphoesters and Thioesters
C. Acid Chlorides
D. Acid Anhydrides
E. Amines
a. Structure and Physical Properties
b. Nomenclature
F. Amides
a. Structure and Physical Properties
b. Nomenclature
Lipids and their Functions (4)
A. Structure and Properties
B. Biological Functions
a. Chemical Reactions
b. Physiological Function
i. Fluid Mosaic Structure
ii. Membrane Transport
iii. Energy Requirements
c. Types
i. Fatty Acids
1. Tryiglycerides
2. Sphingolipids
ii. Eicosanoids
1. Prostaglandins
2. Thromboxanes
3. Leukotrienes
iii. Steroids
Amino Acids, Proteins, and Enzymes (4)
A. The Peptide Bond
B. Proteins in the Blood
C. Structure
a. Primary
i. Stereochemistry
1. D,L-system
ii. Sequence
1. Notation
2. 3-D
b. Secondary
i. α-Helix
ii. β-Pleated Sheet
c. Tertiary
i. Fibroin
ii. Globular Proteins
d. Quaternary
i. Myoglobin
ii. Hemoglobin
D. Enzymes and Structure
a. Classification
b. Effects
i. Activation Energy
ii. Substrate Concentration
iii. Temperature
iv. pH
c. Complexation
i. Specificity
ii. Allosteric
d. Regulation
i. Inhibition
1. Reversible
2. Irreversible
ii. Feedback
e. Clinical Perspectives
Energy Production (2)
A. Mitochondrial Structure
B. Metabolism
a. Kreb’s Cycle
i. Control
ii. Reactions
b. Electron Transport
i. Control
ii. Reactions
C. Degradation of Amino Acids
a. Transamination
b. Urea Cycle
D. Anabolism
Carbohydrate and Fatty Acid Metabolism (4)
A. ATP
a. Carbohydrate Metabolism
i. Glycolysis
1. Control
2. Reactions
ii. Pentose Phosphate Pathway
iii. Gluconeogenesis
iv. Glucogenesis
b. Fatty Acid Metabolism
i. Digestion and Absorption of Triglycerides
1. β-Oxidation
2. Glycerol
ii. Ketone Bodies
1. Ketosis
2. Ketogenesis
iii. Fatty Acid Synthesis
iv. Regulation
Nucleic Acids and Molecular Genetics (3)
A. Introduction
a. Nucleotides
i. Structure of DNA/RNA
ii. Replication
B. Biological Information Flow
a. RNA classes
b. Transcription
c. Protein Synthesis
C. DNA Changes
a. Mutations
b. Engineering
D. Sequencing
3.
Instructional Plan
Students will be introduced to the concepts outlined above. This introduction will include lecture, demonstrations and
group work. The laboratory component will be used as a complement to the lecture to offer students a hands-on environment in
working and experimenting with frequently-encountered topics. This real world experience will offer confirmation and
understanding of chemistry and their application.
Assessment of these plans includes quizzes, homework, exams, laboratory reports, and in-class feedback.
4.
Course requirements
Students are expected to have had high school chemistry or CHEM 108. In addition, they are required to have had
MATH 100 or a qualifying score on the math entrance exam.
Evaluation: Homework, laboratory reports, and exams (including ACS-standardized).
B.
1.
5.
Course materials
There are a number of textbooks available including the currently used
Denniston, K. J. Topping J. J. Caret, R. L.; General, Organic, and Biochemistry, 4th Ed.; McGraw Hill, Madison, WI 2004.
Plus accompanying Laboratory textbook.
6.
References
Rationale
Statement of the major focus and objectives of the course.
The major objective of this course is to offer a connection between chemistry and allied health topics. Students in the health
fields should be familiar with chemical concepts and how they are related to the physiological and biological sciences. The chemistry
department would like to offer nursing and other allied health students a beneficial and appropriate chemistry course that meets the
changing needs of their curriculum. This course presents the groundwork necessary to understand biochemical processes, including
reaction analysis, conversions, and biochemical structure.
This course will fulfill the chemistry requirement for the Nursing- Generic option major.
2.
Specify how this new course contributes to the departmental curriculum.
This course is considered a hybrid of two courses that are currently offered, CHEM 208 and CHEM 209. CHEM 210 will
serve in the same capacity, meeting over one semester for 4 lecture periods and 1 lab period.
3.
Indicate any course(s) which may be dropped if this course is approved.
CHEM 208 and CHEM 209 (4 credits each) will be dropped.
C.
Impact of the course on others
A reduction of 3 SH results in the Nursing – Generic option major. Chemistry and nursing department representatives have
worked together toward a common result. The recently submitted revised nursing major includes this new course.
II.
WINONA STATE UNIVERSITY
FINANCIAL AND STAFFING DATA SHEET
Course or Program____CHEM 210______________________________
Include a Financial and Staffing Data Sheet with any proposal for a new course, new program, or revised program.
Please answer the following questions completely. Provide supporting data.
1.
Would this course or program be taught with existing staff or with new or additional staff? If this course would be taught by adjunct
faculty, include a rationale.
Existing staff would teach this course. This course will be offered instead of CHEM 208 and CHEM 209.
2.
What impact would approval of this course/program have on current course offerings? Please discuss number of sections of current
offerings, dropping of courses, etc.
The chemistry department would plan to offer 5-7 lab sections of this course divided among 2-3 lecture sections each semester. We
currently offer 7 sections each of 208 (fall) and 209 (spring).
3.
What effect would approval of this course/program have on the department supplies? Include data to support expenditures for staffing,
equipment, supplies, instructional resources, etc.
None – this will be offered in place of existing courses.