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NUTRIENT ABSORPTION How many different systems do you see? Digestive-Breaks down and absorbs nutrients 1. 2. Respiratoryabsorbs oxygen 3. Circulatory – transports nutrients C6H12O6 + 6O2 glucose + oxygen 6 CO2 + 6H2O + 36 ATP carbon dioxide + water + energy 1. Where does the glucose come from? Food 2. Where does the oxygen come from? Breathing 3. What are the final products of cellular respiration? CO2, H2O, ATP 4. In which organelle does this take place in our cells? Mitochondria Nutrient Absorption- DIGESTIVE Types of digestive Filter feeder systems: Digestive cavity: Digestive tract: 1 opening 2 openings (Gastrovascular cavity) Description of system Aquatic animals that Digestive chamber with strain tiny floating food entering and waste organisms from water exiting through one 2 openings: mouth, anus. opening. Picture of system Jellyfish, Sea Anemone, Examples Sponges Snails, oysters, squid, octopus, Corals, Portuguese Man-of- starfish, sand dollar, crayfish, War, Planaria (flatworm) spiders, crabs, butterflies, humans Function of The Digestive System The function of the digestive system is to help convert foods into simpler molecules that can be absorbed and used by the cells of the body; eliminates waste. The Digestive System (aka. Alimentary Canal) Includes: Mouth 2. Pharynx 3. Esophagus 4. Stomach 5. Small Intestine 6. Large Intestine/Colon 7. Rectum 8. (Accessory organs: salivary glands, liver, gallbladder, pancreas) 1. The Mouth Teeth Cutting, tearing, and crushing food into small fragments. Begins the process of mechanical digestion or physical breakdown. Saliva Secreted by the salivary glands. Helps moisten the food and make it easier to chew. Contains amylase, a digestive enzyme that begins the breakdown of carbohydrates. Begins the process of chemical digestion, where chemicals breakdown the large pieces into smaller pieces. The Esophagus Bolus – Chewed clump of food. From the throat, the bolus passes through the esophagus, or food tube, into the stomach. Food travels through the esophagus to the stomach by smooth muscle contractions (wave-like) called peristalsis. The epiglottis (small flap covering the trachea) separates the food from air when swallowing The Stomach Food from the esophagus empties into a large muscular sac called the stomach. The stomach continues the mechanical and chemical digestion of food. Mechanical: Stomach muscles contract to churn and mix stomach fluids and food, gradually producing a mixture known as chyme. Chemical: 1. 2. 3. Gastric glands release mucous to protect the stomach wall Gastric glands produce hydrochloric acid and pepsin, which begins the complex process of protein digestion. Amylase is denatured by the stomach acid so carbohydrate breakdown does not occur in the stomach. The Small Intestine Most of the chemical digestion and beginning absorption of the food you eat occurs in the small intestines. The Small Intestine Divided into three parts: 1. 2. 3. Duodenum Jejunum Ileum Together average about 6 meters (19.7 ft) long. Duodenum The first of three parts of the small intestine. It is where almost all of the digestive enzymes enter the intestine. The pancreas and the liver release digestive enzymes and fluids to help with digestion in the small intestine. Absorption in the Small Intestine By the time chyme enters the jejenum and the ileum parts of the small intestine, much of the chemical digestion has been completed. Chyme is now a rich mixture of medium and small nutrient molecules. Absorption in the Small Intestine The small intestine is specially adapted for absorption of nutrients. The folded surfaces of the small intestine are covered with fingerlike projections called villi. Villi increases the surface area for absorption of nutrients Absorption of Nutrients in the Small Intestine Nutrients are absorbed through the wall of the small intestine directly into the capillaries (blood) by the process of diffusion. Diffusion – movement of substances from an area of high concentration to an area of low concentration Absorption in the Small Intestine By the time food is ready to leave the small intestine, it is basically nutrient-free. The complex organic molecules have been digested and absorbed, leaving only water, cellulose, and other undigestible substances behind. The Large Intestine When the chyme leaves the small intestine, it enters the large intestine, or colon. Primary Function: Remove water from the undigested material that is left. The concentrated waste material (feces) that remains after the water has been removed passes through the rectum and is eliminated from the body. http://www.youtube.com/watch?v=Z7xKYNz9AS0 Click on picture Accessory Structures of Digestion 1. 2. 3. 4. Pancreas Liver Gallbladder Salivary Glands Pancreas Located just behind the stomach. Gland that serves three important functions: 1. 2. 3. Produces insulin that regulate blood sugar levels. Produces enzymes that break down carbohydrates, proteins, lipids, and nucleic acids. Produces sodium bicarbonate, a base that neutralizes stomach acid so that these enzymes can be effective. Liver Assisting the pancreas is the liver, a large organ located just above and to the right of the stomach. Produces bile; to help digest fats Bile acts like a detergent, dissolving and dispersing the droplets of fat found in fatty foods. Makes it possible for enzymes to reach the smaller fat molecules and break them down. Bile is stored in a small, pouch-like organ called the gall bladder. Gallbladder https://www.youtube.com/watch?v=TkREXrY4CZc (dr. oz) A pouch like organ that stores the bile The bile is brought to the small intestine by the bile duct 20 million ppl get gallstones, small hard mineral deposits due to excess cholesterol buildup Salivary Glands There are 3 salivary glands: 1. 2. 3. Parotid gland – largest of the salivary glands that secretes saliva to assist with chewing and swallowing; located in the cheek area inferior to the ear Submandibular gland – secretes amylase to help breakdown starches in the mouth; located below and inferior to the parotid gland Sublingual gland – secretes mucous that helps coat the food being swallowed; located in front of the submandibular gland on the floor of the mouth Digestive System Levels of Organization Epithelial cells, Liver cell, stomach cell, pancreatic cell, etc…. epithelium, villi, smooth muscle Mouth, esophagus, stomach, small & large intestines, etc… digestive A. SALIVARY GLANDS B. MOUTH C. ESOPHAGUS D. STOMACH F. LARGE INTESTINE H. ANUS E. SMALL INTESTINE G. RECTUM Digestive System Disorders Peptic Ulcer Hole in the stomach wall Most peptic ulcers are caused by bacteria and most can be cured by antibiotics. Diarrhea or Constipation If not enough water is absorbed by the large intestine, diarrhea occurs. If too much water is absorbed from the undigested materials, constipation occurs. http://www.youtube.com/watch?v=cdijh32NiLs (constipation) NUTRIENT ABSORPTIONC I R C U L AT O R Y T H E C I R C U L AT O R Y S Y S T E M -ALSO CALLED CARDIOVASCULAR SYSTEM CONSISTS OF THE HEART, SERIES OF BLOOD VESSELS , AND THE BLOOD EVOLUTIONARY TRENDS OF THE CIRCULATORY Complex SYSTEM Simple Types of circulatory Diffusion through skin/cells Open circulatory Closed circulatory system system system: Blood is not contained in Blood is contained within a Organisms are thin and most of their a network of blood network of blood vessels cells are close to the external vessels Description of system: environment so materials can pass easily in to and out of their bodies Picture of system: Examples Flatworms Insects, crustaceans, Squid, octopus, Mammals, snails, oysters humans FUNCTIONS OF THE CIRCULATORY SYSTEM • Main Functions: 1.Transports O2 & nutrients (sugars, amino acids, hormones) to the cells 2.Removes wastes from cells • Also, works with the immune system to protect body against disease causing pathogens PARTS OF THE BLOOD • Plasma – thick, yellowish liquid, mostly water, in which blood cells are suspended • Red blood cells (erythrocytes) – Transport O2 to body/ remove CO2 – Red in color due to the hemoglobin (iron containing protein) – Produced in red bone marrow, average life span of 120 days, destroyed by spleen later • White blood cells (leukocytes) – Guard against infection – Some work with the immune system to produce antibodies Platelets: cell fragments a. Stick to broken blood vessels b. Helps body heal wounds by forming clots WHEN YOU GET CUT WHY DOES THE BLEEDING EVENTUALLY STOP? • You have plasma proteins and cell fragments called platelets. • When there is a broken blood vessel, platelets start to accumulate at the site and release clotting factors. These factors form a web (like the pic. to the right) of filaments that stops the bleeding. BLOOD VESSELS Adults have over 60,000 miles of vessels in their bodies The blood volume in our bodies = 8% of our total weight 130lbs = 10.4 lbs of blood! THREE TYPES OF BLOOD VESSELS- Arteries, Veins, and Capillaries 1. Arteries o Large vessels that carry blood AWAY from the heart to the tissues of the body o Except for the pulmonary arteries, all arteries carry oxygen-rich blood. 2. Veins Large vessels that return blood TO the heart. – Have valves to keep blood from flowing backwards – Carrying oxygen-poor blood VALVES ARE ALSO IN THE VEINS Prevent backflow and push blood against gravity to the heart(systemic circulation). One way flow. Leaky valves in extremities can cause blood to “pool”=varicose veins Treatment= • Sclerotherapy (medicine injected into vein) • Vein stripping 3. Capillaries ~Smallest blood vessel; site of gas exchange: brings nutrients and oxygen to the tissues and absorbs carbon dioxide and waste products ~The walls of capillaries are only one cell thick, and most are so narrow that blood cells must pass through them in single file. THE HEART: SOME FACTS • Hollow organ about the size of your clenched fist. • Contracts on average 72 times per minute. • Pumps about 70 mL of blood with each contraction. The Heart 1. Heart – muscular organ 4 chambers Pumps blood from heart to lungs & back to heart, to tissues throughout body 2. Pericardium- outer covering of the heart; provides protection for heart. Myocardium – Heart’s muscular wall that contracts to pump blood out of the heart. 3. Septum: muscular wall in heart Separates right side from left side Keeps O2 poor & O2 rich blood from mixing 4. Atria – 2 upper chambers Receive blood from body (right) or lungs (left) & pump blood into ventricles 5. Ventricles – 2 lower chambers Pump blood out of heart to lungs (right) or aorta (left) The Heart 2 chambers: fish 3 chambers: amphibians, most reptiles 4 chambers: birds, mammals. The 4 chambered heart is more efficient because the oxygenated and deoxygenated blood are never mixed. NATURAL PACEMAKER- “SETS THE PACE” • Sinoatrial node (SA node) – – found in the upper part of the right atrium of the heart – a specialized bundle of neurons that act as the heart's natural pacemaker – the SA node "fires" at regular intervals to cause the heart of beat with a rhythm of about 60 to 70 bpm(healthy, resting). Artificial Pacemaker A medical device placed under your skin near heart which uses electrical impulses, delivered by electrodes contacting the heart muscles, to regulate the beating of the heart if you have arithemias TWO PATHS OF CIRCULATION How the Heart Works….. • Systemic-blood circulates from the heart to the body and back to the heart • Pulmonary-blood circulates from the heart to the lungs and back to the heart CIRCULATION THROUGH THE BODY The heart functions as two separate pumps: 1. Right Side - Pumps oxygen-poor blood to the lungs. o Known as pulmonary circulation 2. Left Side - Pumps oxygen-rich blood to the rest of the body. o Known as systemic circulation PATHWAY OF BLOOD FLOW THROUGH THE HEART 1. Blood enters the heart through the right (3) and left (9) atria. 2. As the heart contracts, blood flows into the ventricles (5, 11). 3. Then out from the ventricles to either the body or the lungs. • Valves – Flaps of connective tissue that prevents blood from flowing backwards. – Exist between the atria and ventricles. – Also exist at the end of the ventricles. HEART BEATS & BLOOD PRESSURE • Normal heart sound – Lub-Dub – “lub” is the bicuspid and tricuspid valve closing and the “dub” is the semilunar valves closing • Blood pressure is the force of the blood on the walls of the arteries. (Systolic over Diastolic) – Diastole – period of time when the heart-atriafills with blood (relaxation) – Systole – the contraction of the ventricles Normal blood pressure is 110/70 CIRCULATORY SYSTEM DISEASES 1. Leukemia: bone marrow produces abnormal WBCs. At first, leukemia cells function normally. In time, there are too many & they crowd out normal WBCs, RBCs & platelets. 2. Hemophilia: an inherited disorder. Afflicted persons cannot produce clotting factors, which causes people w/ hemophilia to bleed for longer periods of time than people whose produce clotting factors. The main problem w/ hemophilia is internal bleeding, mainly into muscles & joints. CIRCULATORY SYSTEM DISEASES • 3. Atherosclerosis- “plaque” (fat) build up on the inner walls of arteries. • 4. Arteriosclerosis: arteries become hard & brittle because calcium is deposited in their walls. Vessels become thickened & lose elasticity. Blood pressure increases & blood clots may form • 5. Stroke: blood clot blocks artery or a blood vessel breaks, interrupting blood flow to an area of the brain. Brain cells begin to die & abilities controlled by that area of the brain are lost. 6. ANEURYSMS • A ballooned bulge in a blood vessel caused by disease or weakening of vessel wall. – Usually found in artery at base of brain or in the aorta – If these rupture then will lead to hemorrhaging and death Circulatory System Red & white blood cells Blood, Blood vessels (smooth muscle) heart circulatory INTERACTIONS AMONG SYSTEMS TO ACHIEVE NUTRIENT ABSORPTION Nutrients are obtained from food that the digestive system has broken down. The respiratory system obtains oxygen from the atmosphere. These nutrients are transported by the circulatory system to cell of the body for absorption. Cellular Respiration - the process by which cells get energy from the breakdown of glucose in the presence of oxygen Takes place in the mitochondria External Respiration - The process of gas exchange between the lungs and the environment. Release carbon dioxide Uptake of oxygen C6H12O6 + 6O2 glucose + oxygen 6 CO2 + 6H2O + 36 ATP carbon dioxide + water + energy 1. Where does the glucose come from? Food 2. Where does the oxygen come from? Breathing 3. What are the final products of cellular respiration? CO2, H2O, ATP 4. In which organelle does this take place in our cells? Mitochondria Simple Types of Diffusion respiratory through system: Complex Gills Tracheal tubes Book lungs Lungs skin/cells Structures of system: Adaptation to land or Water Water Terrestrial, land Terrestrial, land land water? Examples Terrestrial, Sponges, corals, Fish, crayfish, jellyfish, lobsters, crabs planarian, earthworm Insects Spiders Mammals, humans To bring about the exchange of oxygen and carbon dioxide between the blood, the air, and tissues. Diaphragm – Large, flat muscle at the bottom of the chest cavity that helps with breathing. Inhaling (Breathing in) Ribs rise, diaphragm contracts, fills chest cavity. Exhaling (Breathing out) Passive event Ribs lower, diaphragm relaxes, empties chest cavity. http://www.youtube.com/watch?v=HiT621PrrO0 https://www.youtube.com/watch?v=2RZjDl -2_24 1. 2. 3. 4. Nose (Nasal cavity) Pharynx (Throat) Larynx (Voice Box) Trachea(Windpipe) Glottis 2. Epiglottis 1. 5. 6. Bronchi-Rt.— Lft. Lungs-Rt.(3 lobes)— Lft.(2Lobes) Bronchioles 2. Alveoli-lined w/cappillaries=d iffusion 1. 7. Diaphragm Where air enters and exits the body Nose hairs – trap dust and unwanted particles Nasal chamber – warms and moistens air before it enters the respiratory system Air moves through the nose to a tube at the back of the mouth called the pharynx, or throat. Pharynx - Serves as a passageway for both air and food. Located between the pharynx and top of trachea. Contains two highly elastic ligaments known as the vocal cords. When muscles pull the vocal cords together, the air moving between them causes the cords to vibrate and produce sounds. Your ability to speak, shout, and sing comes from these tissues. Air moves from the pharynx into the trachea, to the lungs. Opening of trachea is called glottis. A flap of tissue called the epiglottis covers the entrance to the trachea (glottis) when you swallow The glottis is covered by epiglottis and prevents choking. Lined with cartilage rings, cilia Cilia in the trachea. From the larynx, air passes through the trachea into two large passageways in the chest cavity called bronchi. Each bronchus leads into one of the lungs. The large bronchus subdivides into smaller bronchi, which lead to even smaller passageways called bronchioles. Surrounded by smooth muscle enabling the nervous system to regulate the size of the air passageways. The bronchioles continue to subdivide until they reach a series of dead ends—millions of tiny air sacs called alveoli. Grouped in little clusters, like bunches of grapes. A delicate network of thinwalled capillaries surrounds each alveolus. This is where gas exchange occurs because blood (capillaries) and air are side by side. O2 is put into the blood and C02 is removed from the blood Each healthy lung contains about 150 million alveoli ! Provides for an enormous surface area for gas exchange. Oxygen Dissolves in the moisture on the inner surface of the alveoli and then diffuses across the thin-walled capillaries into the blood. Carbon Dioxide in the Bloodstream Diffuses in the opposite direction, across the membrane of an alveolus and into the air within it. You have some voluntary control over breathing. The medulla oblongata in the brain also monitors carbon dioxide levels in the blood. It forces you to breathe even if you are trying to hold your breathe. As the CO2 levels rise, nerve impulses from the brain cause the diaphragm to contract, bringing air into the lungs. Respiratory System Levels of Organization lung cell alveoli mouth, nose, trachea, bronchi, bronchioles, diaphragm respiratory After food is broken down/digested, what system do the molecules diffuse to? After you take a breath, in to what system does the oxygen diffuse to? The upper respiratory tract can usually filter out dust and foreign particles that could damage the lungs. Tobacco smoke contains nicotine, carbon monoxide, and tar all of which paralyze the cilia. With no working cilia these particles stick to and enter the lungs. Smoking can cause chronic bronchitis, emphysema, and lung cancer. Destroys alveoli and the damage is irreversible