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CHAPTER 25 The Urinary System PART A Learning objectives 1. 2. 3. 4. Recognize and name the organs of urinary system according to their location in the abdominal and pelvic cavity(ILO .(ILO 1.1) Define the terms related to urinary system.(1.2) Recognize and contrast histology of different parts of nephron.(ILO 2.1) Label the anatomical and histological features of urinary system in the activity sheets(ILO 2.2) Lecture outlines 1. 2. Urinary System Organs Kidney Anatomy 3. 4. External Internal Nephron Parts of nephron Urinary System Organs 1. 2. 3. 4. Kidneys Ureters Urinary bladder Urethra Urinary System Organs • Kidneys are major excretory organs • Ureters transport urine from the kidneys to the bladder • Urinary bladder is the temporary storage reservoir for urine • Urethra transports urine out of the body Copyright © 2010 Pearson Education, Inc. Hepatic veins (cut) Esophagus (cut) Inferior vena cava Adrenal gland Aorta Renal artery Renal hilum Renal vein Kidney Iliac crest Rectum (cut) Uterus (part of female reproductive system) Copyright © 2010 Pearson Education, Inc. Ureter Urinary bladder Urethra Figure 25.1 External anatomy of Kidney Anatomy • Retroperitoneal, in the superior lumbar region • Right kidney is lower than the left • Convex lateral surface, concave medial surface Copyright © 2010 Pearson Education, Inc. Anterior Inferior vena cava Peritoneum Peritoneal cavity (organs removed) Renal vein Renal artery Copyright © 2010 Pearson Education, Inc. Supportive tissue layers • Renal fascia anterior posterior • Perirenal fat capsule • Fibrous capsule Body of vertebra L2 Body wall (a) Aorta Posterior Figure 25.2a External anatomy of Kidney Anatomy • Renal hilum on the medial surface --Ureters, renal blood vessels, lymphatics, and nerves enter and exit at the hilum Copyright © 2010 Pearson Education, Inc. External anatomy of Kidney Anatomy Copyright © 2010 Pearson Education, Inc. Internal Anatomy of kidney • Renal cortex • A granular superficial region • Renal medulla • The cone-shaped medullary (renal) pyramids separated by renal columns Copyright © 2010 Pearson Education, Inc. Internal Anatomy of kidney • Papilla • Tip of pyramid; releases urine into minor calyx • Renal pelvis • The funnel-shaped tube within the renal sinus Copyright © 2010 Pearson Education, Inc. Internal Anatomy of kidney • Major calyces • The branching channels of the renal pelvis that • Collect urine from minor calyces • Empty urine into the pelvis • Urine flows from the pelvis to ureter Copyright © 2010 Pearson Education, Inc. Copyright © 2010 Pearson Education, Inc. Renal hilum Renal cortex Renal medulla Major calyx Papilla of pyramid Renal pelvis Minor calyx Ureter Renal pyramid in renal medulla Renal column Fibrous capsule (a) Photograph of right kidney, frontal section Copyright © 2010 Pearson Education, Inc. (b) Diagrammatic view Figure 25.3 Nephrons • Structural and functional unit of the kidney that form urine • Up to 1 million nephrons per kidney • Two main parts 1. Renal corpuscle (cortex) 2. Renal tubule (cortex medulla) Copyright © 2010 Pearson Education, Inc. Parts of nephron 1. Bowman’s capsule 2. Glomerulus 3. Proximal convoluted tubule 4. Loop of Henle 5. Distal convoluted tubule 6. Collecting tubule Copyright © 2010 Pearson Education, Inc. Copyright © 2010 Pearson Education, Inc. Figure 25.5 Glomerular capsule: parietal layer Renal cortex Renal medulla Basement membrane Renal corpuscle • Glomerular capsule • Glomerulus Renal pelvis Ureter Podocyte Distal convoluted tubule Kidney Fenestrated endothelium of the glomerulus Glomerular capsule: visceral layer Microvilli Mitochondria Proximal convoluted tubule Highly infolded plasma membrane Proximal convoluted tubule cells Cortex Medulla Thick segment Thin segment Loop of Henle • Descending limb • Ascending limb Distal convoluted tubule cells Collecting duct Loop of Henle (thin-segment) cells Principal cell Intercalated cell Collecting duct cells Copyright © 2010 Pearson Education, Inc. Figure 25.5 Copyright © 2010 Pearson Education, Inc.