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Learning Objectives: (1) Name the chemical elements of the body and their chemical symbols (abbreviations). Chapter 2 A Crash Course in Biochemistry from a Local Medical Lab (2) Identify the basic four organic compounds of life (carbohydrates, lipids, proteins and nucleic acids). State their types and functions. (3) Explain the significance of checking your blood cholesterol levels. What is involved? How do you interpret the test(s)? (4) Explain how atoms and molecules are constructed. (5) Discuss the unique significance of ions, electrolytes and free radicals in the human body. Organic Molecules of Life 4 Organic Molecules: 1. __________ 2. Carbohydrates 3. Proteins 4. _______ Acids What do you already know about lipids? LIPIDS (also known as ____) Made up of: carbon, hydrogen and ____________ 5 types of lipids: 1. Fatty acids – source of energy; precursor to trigycerides 2. Triglycerides – involved in _________ storage, thermal insulation, and binding and cushioning _______________. 3. Phospholipids – aids in _______ digestion; component of cell membranes 4. Eicosanoids - _____________ messengers between cells 5. Steroids - _______________ (or chemical messengers between cells) Carbohydrates (sugars and ___________) Carbohydrates/ Type Function Monosaccharides (simple sugars) i.e. glucose _____ sugar; source of energy Disaccarides (two simple sugars put together) i.e., sucrose (glucose + fructose) _______ sugar Polysaccharides (two or more sugars strung together) i.e., starch Energy storage in ______; source of fuel for us Protein Type Function Amino acid - i.e., alanine Building blocks of ________ Enzymes – i.e., amylase Catalyst (amylase digests _____) Nucleic Acids Type Function Deoxyribonucleic acid (DNA) Hereditary material; constitutes all _________; what makes you unique; located inside a cell’s ________________ Ribonucleic acid (RNA) Carries out instructions in a cell to make __________ Elements (a pure substance with all the same atoms and molecules) in the Human Body An element is the __________ form of matter that retains unique properties. There are ______ naturally occurring elements here on Earth. Only _____ of these play an essential role in the human body. Major Elements in the Human Body Oxygen or ___ Carbon or ___ Hydrogen or _____ Nitrogen or _____ Calcium or ____ Phosphorus or ____ Trace Elements: Chromium or __ Copper or ___ Iodine or ___ Molybdenum or ___ Silicon or ____ Vanadium or ____ Lesser Elements in the Body: Sulfur or ____ Potassium or ___ Sodium or ___ Chlorine or ____ Magnesium or ____ Iron or ____ Cobalt or ___ Fluorine or ______ Manganese or _____ Selenium or ____ Tin or _____ Zinc or ___ * Many of these are minerals that are needed by the body (at least 4% of the body’s weight) Compounds Compounds are ___ or more elements put together Example: Salt = ____________ + ____________________ Atoms Atoms are the ________________ particle of any element. Made up of sub-particles: 1. protons which carry a ____ charge 2. neutrons which carry ___ charge 3. electrons which carry a _____ charge Typically, the number of protons = the number of __________ in a stable atom. Atoms are held to other atoms by special bonds called _____________ bonds. A chemical bond is the “glue” that holds two or more atoms together. Also holds molecules together. Ions Ions are _______________ with unequal numbers of protons and electrons. Ions with __________________ charges (+ or -) are often attracted to one another and will follow one another through the body. Sodium (Na+) and chloride (Cl-) which have opposite charges, demonstrate an ionic attraction for one another. Electrolytes Electrolytes are _______________ that ionize (or give off) ions in water like acids, _______________, and salts. Found in __________ drinks. Capable of __________ electricity. The electrical current in the brain, for example, can be measured because electrolytes found in body fluids conduct electrical currents from that organ back to the skin’s surface and can be measured using electrodes. Free Radicals Ever heard of a free radical? What are free radicals? They are very _______________ chemical particles that typically have an odd number of ____________________ and are thought of as destructive to your body’s cells. Examples: meat containing nitrates like bacon, sausage, and hot dogs. Also meat that is charred on the grill. Note: the burning of meat & fat on the grill creates polycyclic aromatic hydrocarbons which is known to be cancer-causing