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Material elaborado en Médicos del Mundo Canarias (Tenerife) SEXUALLY TRANSMITTED DISEASES (STD’S) SYPHILIS WHAT IS SYPHILIS? Syphilis is a sexually transmitted disease (STD). It’s caused by the Treponema Pallidum bacteria. It is called “the great imitator”. SYPHILIS SYPHILIS HOW IS SYPHILIS TRANSMITTED? Syphilis IS TRANSMITTED by: Direct contact with a syphilitic ulcer. The ulcers mainly appear on the external genitals, the vagina, the anus or the rectum. They can also appear on the lips and in the mouth. The transmission of the bacteria occurs during vaginal, anal and oral sex. Pregnant women that have this disease can transmit it to their babies. HOW IS SYPHILIS NOT TRANSMITTED? Syphilis IS NOT TRANSMITTED by: Contact with toilets. Door handles. Sharing pools, normal or whirlpool baths. Sharing clothes or cutlery. WHICH ARE ITS SIGNS AND SYMPTOMS? Syphilis presents 3 stages according to its signs and symptoms: Primary syphilis Secondary syphilis Latent and late syphilis Many people that have syphilis don’t present any symptoms for years. Many people who are in the primary or secondary stages of the disease can transmit it to their partners even though in many cases syphilitic ulcers cannot be recognized. People who do not know they have been infected can transmit the disease. PRIMARY SYPHILIS The primary stage is mostly marked by the appearance of a single sore (called a chancre). The time that passes between the infection of syphilis and the appearance of the first symptom can be from 10 to 90 days (with an average of 21 days). The chancre is firm, round, small and painless. It appears in the place where the syphilis entered the organism. The chancre lasts from 3 to 6 weeks and disappears without being treated. PRIMARY SYPHILIS PRIMARY SYPHILIS Open sore or chancre Treponema pallidum bacteria PRIMARY SYPHILIS PRIMARY SYPHILIS PRIMARY SYPHILIS PRIMARY SYPHILIS PRIMARY SYPHILIS PRIMARY SYPHILIS PRIMARY SYPHILIS SECONDARY SYPHILIS 1 Skin rashes and mucous membrane lesions appear. This stage usually begins with a rash in one or more areas of the body. The The rashes generally aren’t itchy. rashes associated with secondary syphilis can appear when the chancre is healing or weeks after it has healed. SECONDARY SYPHILIS 2 The characteristic rash of this stage may appear as rough, red or reddish brown spots, both on the palms of the hands and the bottoms of the feet. Rashes with a different appearance may occur on other parts of the body, sometimes resembling rashes caused by other diseases. Sometimes, they are so faint that they are not noticed. In addition to rashes, symptoms of secondary syphilis may include fever, swollen lymph glands, sore throat, patchy hair loss, headaches, weight loss, muscle aches, and fatigue. The signs and symptoms of secondary syphilis will resolve with or without treatment, but without treatment, the infection will progress to the latent and possibly late stages of disease. SECONDARY SYPHILIS SECONDARY SYPHILIS SECONDARY SYPHILIS SECONDARY SYPHILIS SECONDARY SYPHILIS SECONDARY SYPHILIS SÍFILIS SECUNDARIA SÍFILIS SECUNDARIA SECONDARY SYPHILIS LATENT & LATE SYPHILIS 1 It’s also called the hidden stage of syphilis. It begins with the disappearance of the symptoms of the first and secondary stages. Without treatment, the infected person will continue to have syphilis even when they no longer present signs or symptoms, as the infection remains in the body. This latent stage can last for years. The late stages of syphilis can develop in about 15% of people who have not been treated for the primary stages, the disease can advance and appear 10–20 years after infection was first acquired. LATENT & LATE SYPHILIS 2 In this advanced stage syphilis may subsequently damage the internal organs including: The brain The nerves The eyes The heart Blood vessels The liver Bones The joints LATENT & LATE SYPHILIS 3 The damage caused in this stage can be serious and cause death. The signs and symptoms of this latent stage of syphilis include: Difficulty coordinating muscle movements Paralysis Numbness Gradual blindness and dementia. LATENT & LATE SYPHILIS Liver Bone Heart Brain The bacteria spreads to various organs and causes lesions. LATENT & LATE SYPHILIS HOW IS SYPHILIS DIAGNOSED? 1 There are two ways of diagnosing a syphilis infection: Via a blood test: Shortly after a person is infected they begin to produce antibodies against the syphilis that can be detected by an accurate, safe and inexpensive blood test. A low level of antibodies will likely stay in the blood for months or years even after the disease has been successfully treated. Because untreated syphilis in a pregnant woman can infect and possibly kill her developing baby, every pregnant woman should have a blood test for syphilis. HOW IS SYPHILIS DIAGNOSED? 2 The other way to diagnose syphilis Is by examining material from a chancre (infectious sore) using a special microscope called a darkfield microscope. If syphilis bacterium are present in the sore, they will show up when observed through the microscope. WHICH EFECTS DOES SYPHILIS HAVE ON PREGNANT WOMEN AND THEIR BABIES? The syphilis bacteria can infect the baby during pregnancy. Depending on the time in which a pregnant woman has been infected, there could be a high risk of having a stillborn or of the baby dying after birth. An infected baby can be born without the signs and symptoms of the disease. However, if it is not immediately treated, the baby could present some serious symptoms after some weeks. If these babies do not receive treatment, they may suffer developmental delays, convulsions or death. CONGENITAL SYPHILIS CONGENITAL SYPHILIS CONGENITAL SYPHILIS CONGENITAL SYPHILIS WHAT IS THE LINK BETWEEN SYPHILIS AND HIV The syphilitic genital ulcers (chancres) make it easier to acquire and transmit the HIV infection sexually. There is an estimated 2- to 5-fold increased risk of acquiring HIV if exposed to that infection when syphilis is present. Ulcerative STDs that cause sores, ulcers, or breaks in the skin or mucous membranes, such as syphilis, disrupt barriers that provide protection against infections. WHAT IS THE TREATMENT FOR SYPHILIS? Syphilis is easy to heal in its early stages. A single intramuscular injection of penicillin, an antibiotic, will cure a person who has had syphilis for less than a year. Additional doses are needed to treat someone who has had syphilis for longer than a year. For people who are allergic to penicillin, other antibiotics are available to treat syphilis. Treatment will kill the syphilis bacterium and prevent further damage, but it will not repair damage already done. Persons who receive syphilis treatment must abstain from sexual contact with new partners until the syphilis sores are completely healed. Persons with syphilis must notify their sex partners so that they also can be tested and receive treatment if necessary. WILL SYPHILIS RECUR? Having syphilis once does not protect a person from getting it again. Following successful treatment, people can still be susceptible to re-infection. Because syphilitic sores can be hidden in the vagina, rectum, or mouth, it may not be obvious that a sex partner has syphilis. Which is why it is necessary to be re-tested for syphilis after being having finished the treatment. HOW FREQUENT IS SYPHILIS - “Experts recognize an increase in incidence of syphilis and tuberculosis in developed countries.” 22nd of March (noticiadesalud.blogspot.com) - “The Balearics is the region with the highest rate of syphilis with almost 100 cases in 2009” 22nd of March (noticiadesalud.blogspot.com) - “Syphilis has duplicated in 10 years due to a relaxation in sexual protection” 19th of March 2008 (elpais.es) - “20% rise in cases of syphilis, with a daily average of almost one patient” The latest health data figures show that 355 were infected in the last year, 164 of those had various partners. 3rd of May 2010 (levante-emv.com) HOW FREQUENT IS SYPHILIS? According to the Canarian government’s PUBLIC HEALTH ADMINISTRATION DEPARTMENT: The figures of sexually transmitted diseases in the Canaries, including aids, are experiencing an increase in frequent years as is everywhere in our surroundings , especially in the young population (between 15 & 35 years old) in both heterosexuals and homosexuals. The cause of this increment is due to the lack in use of protection (barrier methods like the preservative) during sexual relations. HOW FREQUENT IS SYPHILIS? According to the Canarian government’s PUBLIC HEALTH ADMINISTRATION DEPARTMENT: The incidence rates of syphilis and gonococcal infections (gonorrhea) declared to the Public Health’s Administration Department’s Epidemiological Register, there are 12.85 cases of syphilis per 100.000 inhabitants and 8.93 gonococcal infections per 100.000 inhabitants. The incidence rates of these two pathologies are: 5.7 cases of syphilis per 100.000 inhabitants, and 4.25 cases of gonococcal infection per 100.000 inhabitants. The incidence rates of cases of aids in the Canary Islands in 2008 is of 21.72 cases per 1.000.000 inhabitants. HOW CAN SYPHILIS BE PREVENTED 1 The surest ways to avoid the transmission of syphilis are: Abstain from sexual contact. Be in a stable and mutually monogamous relationship with a partner that has been tested and is known to be uninfected. Avoiding alcohol and drug use may also help prevent transmission of syphilis because these activities may lead to risky sexual behavior. It is important that sex partners talk to each other about their HIV status and history of other STDs so that preventive action can be taken. The correct and frequent use of condoms can reduce the risk of contracting syphilis, genital herpes and chancres, always and when the infected area or the area of possible contact is covered. HOW CAN SYPHILIS BE PREVENTED 2 Condoms lubricated with spermicides are no more effective than other lubricated condoms in protecting against the transmission of syphilis and other STDs. The transmission of an STD, including syphilis, cannot be prevented by washing the genitals, urinating and/or showering after sex. Any unusual discharge, sore, or rash, particularly in the groin area, should be a signal to refrain from having sex and to see a doctor immediately. REVIEW Cause Transmission via Symptoms Diagnosis Treatment Blood test from 15 days after infection. Treatment with antibiotics which requires comprehensive monitoring. First stage: Primary Syphilis (chancre) Redish ulcer in the infected area and infection of the lymph nodes of the nearest areas to the lesion (mouth, genitals or rectum). Heals in 3 to 6 weeks. Bacteria -Anal & vaginal Secondary stage: Secondary penetration Syphilis (rashes, warty or mucous (elevated risk) patches) Rashes on the chest, extremities and hands, lymph nodes of the -Oral sex and neck, armpits and groin, fever, hair kissing if a loss and general malaise. lesion is present. Third stage: Latent & late syphilis Ulcers on the skin, arthritis, lesions on the heart and blood vessels, brain and spinal cord. ANY QUESTIONS ABOUT SYPHILIS? Thank you very much for you attention! If you have any questions, consultations, suggestions…you can make them at: Médicos del Mundo Plaza de la Constitución nº9, 1ºJ. Arrecife. 35500 Telephone: 928-80-55-55 Fax: 928-80-55-55 Mobile: 649-89-84-63 E-mail: [email protected] Web: www.medicosdelmundo.org