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Michael Marks †,‡,*, Oriol Mitjà§,**, Anthony W. Solomon , Kingsley
Michael Marks †,‡,*, Oriol Mitjà§,**, Anthony W. Solomon , Kingsley

- LSHTM Research Online
- LSHTM Research Online

Cost-Effectiveness of Routine Screening for Sexually Transmitted Diseases Among Inmates in United
Cost-Effectiveness of Routine Screening for Sexually Transmitted Diseases Among Inmates in United

Guide for Self-study students to prepare for practical lesson
Guide for Self-study students to prepare for practical lesson

(PBMC) of syphilitic patients to produce IL-2
(PBMC) of syphilitic patients to produce IL-2

Syphilis: using modern approaches to understand an old disease
Syphilis: using modern approaches to understand an old disease

presentation source
presentation source

... activity of each  Use a series of no more than four diagrams to describe the mechanism of ??? activity  Describe the clinical manifestions ???  Construct a table listing the common ??? species and the associated human diseases. ...
Syphilis reinfections pose problems for syphilis
Syphilis reinfections pose problems for syphilis

... carried out for persons attending the HIV/STI clinic at the ITM from 1 January 1992 to 31 December 2012. From 2000, people at-risk attending the clinic were routinely screened 6–12 monthly with a rapid plasma reagin (RPR) test (Becton, Dickinson and Company, United States (US)) – a non-treponemal te ...
Hepatitis C Virus Infections among young adults – rural Wisconsin
Hepatitis C Virus Infections among young adults – rural Wisconsin

The Puzzle of Syphilis - Trace: Tennessee Research and Creative
The Puzzle of Syphilis - Trace: Tennessee Research and Creative

Molecular Characterization of Syphilis in Patients in Canada
Molecular Characterization of Syphilis in Patients in Canada

General Characteristics of the Organism
General Characteristics of the Organism

Syphilis Total Antibody EIA Test Kit Package Insert
Syphilis Total Antibody EIA Test Kit Package Insert

Congenital syphilis guidelines for the Northern Territory
Congenital syphilis guidelines for the Northern Territory

Predictors of Serological Cure and Serofast State
Predictors of Serological Cure and Serofast State

SYPHILIS
SYPHILIS

... the cortical parenchyma, and abundant spirochetes in the tissues. With effective penicillin therapy, this disease has become much less common; In the US, first admissions to mental hospitals because of syphilitic psychosis declined from 7694 in 1940 to 154 in 1968, the last year for which definite f ...
Review on Serologic Diagnosis of Syphilis
Review on Serologic Diagnosis of Syphilis

... In non-treponemal serologic test, such as Venereal Disease Research Laboratory (VDRL) and Rapid Plasma Reagin (RPR), the antibodies to be measured are non-specific treponemal antibodies. It is based upon the reactivity, both IgM and IgG, of sera from patients with syphilis to non-specific cardiolipi ...
Maternal syphilis: pathophysiology and treatment
Maternal syphilis: pathophysiology and treatment

... Although it is not yet clear why some fetuses are more affected than others and there is limited information to explain the pattern of involvement, recent work provides a better understanding of the sequence of involvement. Hollier et al. (28) studied 24 pregnant women with untreated syphilis at 24– ...
Primary syphilis
Primary syphilis

Neurosyphilis as a Cause of Facial and
Neurosyphilis as a Cause of Facial and

Congenital syphilis: No longer just of historical interest
Congenital syphilis: No longer just of historical interest

Syphilis - MedTorrents
Syphilis - MedTorrents

Syphilis: An update - Suffolk Root Canal
Syphilis: An update - Suffolk Root Canal

Chlamydia and Gonorrhea - OSU Center for Continuing Medical
Chlamydia and Gonorrhea - OSU Center for Continuing Medical

Diagnosis and Management of Syphilis
Diagnosis and Management of Syphilis

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History of syphilis



The history of syphilis has been well studied, but the exact origin of syphilis is unknown. There are two primary hypotheses: one proposes that syphilis was carried to Europe from the Americas by the crew of Christopher Columbus, the other proposes that syphilis previously existed in Europe but went unrecognized. These are referred to as the ""Columbian"" and ""pre-Columbian"" hypotheses.In late 2011, newly published evidence suggested that the Columbian hypothesis is the valid one.Skeletal evidence that reputedly showed signs of syphilis in Europe and other parts of the Old World before Christopher Columbus made his voyage in 1492 does not hold up when subjected to standardized analyses for diagnosis and dating, according to an appraisal in the current Yearbook of Physical Anthropology. This is the first time that all 54 previously published cases have been evaluated systematically, and bolsters the case that syphilis came from the New World.The first written records of an outbreak of syphilis in Europe occurred in 1494/1495 in Naples, Italy, during a French invasion. Because it was spread by returning French troops, the disease was known as ""French disease"", and it was not until 1530 that the term ""syphilis"" was first applied by the Italian physician and poet Girolamo Fracastoro. The causative organism, Treponema pallidum, was first identified by Fritz Schaudinn and Erich Hoffmann in 1905. The first effective treatment (Salvarsan) was developed in 1910 by Sahachirō Hata in the laboratory of Paul Ehrlich which was followed by the introduction of penicillin in 1943. Many famous historical figures including Franz Schubert, Arthur Schopenhauer, and Édouard Manet are believed to have had the disease.
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