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Pediatric ECG Click on Box for details ECG Basics: What is an ECG? ECG Basics: ECG interpretation. ECG Basics: Acquiring an ECG. NEED HELP? ECG Basics I ● ECG is a tracing of the heart's electrical activity from different “views” (=leads) ● Each “view” (= lead) produces a wave with height (mm) and duration (msec) ● WAVES are: P, QRS, T ● Intervals contain a WAVE and a SEGMENT: ○ PR and QT intervals ● Segments are time between WAVES ○ ST Segment ECG Basics II ● There are normal ranges for age for the: ○ HEIGHTS of the waves ○ DURATIONS of the waves, intervals and segments ○ AXIS of the waves in the Frontal plane ECG Basics III ● 12 Leads: ○ FRONTAL=LIMB: I, II, III, aVF, aVL, aVR ○ HORIZONTAL=PRE-CORDIAL: V1, V2, V3, V4, V5, V6 ● The AXIS of any wave = the direction the wave “POINTS” in the FRONTAL PLANE of the body ECG Basics IV ECG Basics V ECG Basics VI ● FRONTAL plane is based on LIMB LEADS ● One can estimate the DIRECTION that the ECG WAVE vector points in the FRONTAL plane ● Simple approach is to just examine LIMB LEADS I and aVF ● In this way the AXIS of the heart's electrical signal is determined relative to the FRONTAL plane of the body ECG Basics VII ● QRS is UPRIGHT in LEAD I, therefore it is pointing towards LEAD I, somewhere between +90 and -90 degrees ECG Basics VIII ● QRS is UPRIGHT in LEAD aVF, therefore the AXIS is somewhere between 0 and +90 degrees ● All waves (P, QRS, T) have AXIS in the FRONTAL plane with normals for age ECG Basics IX: Normal QRS AXIS for AGE CLICK to RETURN CLICK HERE for HOME SLIDE ECG Basics: Lead Placement I ECG Basics: Lead Placement II ● Remove all clothing/jewelry from waist up ● Clean skin site with an alcohol pad, dry with a gauze pad; shave hair if necessary ● When reapplying electrodes, ensure any gel residue is removed and electrodes changed. ● Electrodes must always be kept in an air-tight container ==========> ● Good skin preparation prior to electrode attachment is very important ○ Poor skin-electrode contact leads to artifact ECG Basics: Lead Placement III ● RL- On right leg (inside calf, midway between ankle and calf muscle) ● LL- On left leg (inside calf, midway between ankle and calf muscle) ● RA- Right arm (on the inside, halfway between wrist and elbow) ● LA- Left arm (on the inside, halfway between wrist and elbow) ● V1- 4th intercostal space, at right sternal margin ● V2- 4th intercostal space, at left sternal margin ● V3- Midway between V2 and V4 ● V4- 5th intercostal space at left midclavicular line ● V5- Same transverse level as V4, at anterior axillary line ● V6- Same transverse level as V4, at left midaxillary line ECG Basics: Lead Placement IV ECG Basics: Lead Placement V CLICK HERE for HOME SLIDE CLICK HERE for Examples of Poor Tracings Pediatric ECG: Interpretation Click on diagram to link to detailed information Click on Box for details: ECG Scale Values RATE Calculation Rhythm CLICK HERE for HOME SLIDE ECG Basics: Scale ● Standard paper speed (horizontal scale) is 25mm/sec ● Standard vertical scale 10.0mm = 1mV ● Small box = = 1mm x 1mm = 40 msec x 0.1 mV ● VERTICAL values are typically in mm ● HORIZONTAL values are typically in msec CLICK to RETURN Rate: Calculation ● Standard paper speed is 25mm/sec ● Therefore: ○ Each little box is 0.04 seconds = 40 msec ○ Each big box is 0.2 seconds = 200 msec ● Therefore to determine HEART RATE: ○ Count the # of big boxes between QRS beats ○ Divide 300/(# big boxes) = RATE (or) ○ Divide 60,000/time in msec = RATE Rate: Examples ● Therefore to determine HEART RATE: ○ Count the # of big boxes between QRS beats ○ Divide 300/(# big boxes) = RATE (or) ○ Divide 60,000/time in msec = RATE 3 boxes = 600 msec HR=100 4 boxes = 800 msec HR=75 Rate: Normals Rate: Normals CLICK to RETURN Rhythm I ● Normal Sinus Rhythm definition: ○ P-wave AXIS is UPRIGHT in I and aVF ○ P-wave before every QRS ○ QRS after every P-wave ○ Normal PR interval Rhythm II ● Automatic ECG machine read for rhythm is in general very reliable ● Basics: ○ Early = Premature beats are common in the general population and in isolation are not typically dangerous ○ All tachycardias are abnormal and concerning CLICK to RETURN P-Wave ● Atrial depolarization ● Normal Morphology = upright in limb leads I, II and aVF Atrial Enlargement CLICK to RETURN PR Interval ● Definition = time from the beginning of the Pwave to the beginning of the Q-wave PR Duration Normals (=PR interval) CLICK to RETURN QRS Wave ● Ventricular depolarization Abnormal Length Abnormal Morphology Abnormal Size (=height) LEAD V1 Abnormal AXIS CLICK to RETURN QRS Duration Normals CLICK to RETURN QRS Morphology Abnormals ● Incomplete RBBB ● RBBB CLICK to RETURN Incomplete RBBB – borderline long QRS duration of 90-100msec, with a rSR’ – “rabbit ears” in V1. This is a frequent normal variant. Real RBBB = pathologic, wide QRS, typically after heart surgery, very unusual in a peds patient who has not has cardiac surgery; should be evaluated LVH: S Wave in V1 RVH: R wave in V1 CLICK to RETURN QT Interval: Avoiding Toxicity ● Careful review of SCREENING ECGs, including QTc interval will be key to minimizing risk. ● Those with clearly prolonged QTc will be excluded from study. ● Once a patient passes screening, the focus of the serial ECG will be on accurately measuring and calculating QTc ● The automated readings by the ECG machine is generally quite accurate - as long as: ○ The ECG is high quality with clearly seen T-waves and minimal baseline artifact ○ The HR is within the normal range for age QT Interval: Poor Quality ECG Tracings QT Interval: Poor Quality ECG Tracings QT Interval: Poor Quality ECG Tracings CLICK HERE for More on QTc CLICK HERE for HOME SLIDE QT Interval: How to Measure. ● Definition = time from the start of the QRS to the end of the T-wave ● Measured in LIMB LEAD II or V5 ● Correct for HR using ○ QTc = “QT-corrected” ○ QTc = ○ Frederica Correction ○ RR=time between “R-waves” ○ RR in SECONDS ● Upper limit of Normal Duration = QTc<455msec QT Interval: How to Measure. QTc= ● RR interval =14.5 boxes =14.5 x 40msec =580msec =0.58sec =0.8339 ● QT=9.5 boxes =380msec ● Therefore the QTc = 380/0.8339 =456msec ONLINE CALCULATOR https://www.medcalc.org/clinicalc/corrected-qt-interval-qtc.php QT Interval: HR, RR and cubed root Table. QTc = Adverse Event Grading: Appendix V Cardiac Toxicity Management: Appendix VI Prolonged QTc can lead to Ventricular Tachycardia (VT) Prolonged QTc can lead to Ventricular Tachycardia (VT) CLICK to RETURN CLICK HERE for HOME SLIDE T-waves ● Ventricular RE-polarization Abnormal Morphology ST Segment ● Definition = time from the end of the QRS to the beginning of the T-wave ● Normal ST-segment is FLAT = on the same horizontal level as the TP and PR intervals ST Segment and T-waves ● Automatic ECG machine read on ST-segment and T-waves is in general very reliable ● Basics: ○ ST-segment should be FLAT ■ Can be +/- 1mm ○ T-Waves AXIS in FRONTAL PLANE is 0 to +60 ○ T-Waves are UPRIGHT in V4-V6 ○ T-Waves are NEGATIVE in V1-V3 from infancy to early adolescence CLICK to RETURN CONTACT and REFERENCE MATERIALS James Nielsen, MD ● EMAIL: [email protected] ● SKYPE (USA NUMBER): 917-623-7806 Drug List – QT Problem ● FAX (USA NUMBER): 1-888-252-2907 https://www.crediblemeds.org/ QUINTILES: ● Investigator ECG Manual: https://drive.google.com/open?id=0B6mKMisaYx1cMkhrZm40cVhFdVE ● VISIT CODE POSTER: https://drive.google.com/open?id=0B6mKMisaYx1cX1lVUkdPVF9hR0E ● ECG ABNORMALITY CRITERIA: https://drive.google.com/open?id=0B6mKMisaYx1cYk9LeW1KbV9paEk CLICK HERE for HOME SLIDE