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EAST PENNSBORO AREA SCHOOL DISTRICT Unit: COURSE: Evolution — Adaptation 208 Applied Biology Subject(s): Science Days: 14 Grade(s): 10, 11 Key Learning(s): Instructional Tools: 3.1.10.C2 Explain the role of mutations and gene recombination in changing a population of organisms. Unit Essential Question(s): How do adaptations, mutations and recombinant DNA change a population of organisms? Concept: Describe the theory suggesting that life on Earth arose as a single, primitive prokaryote about 4 billion years ago and that for the next 2 billion years, a huge diversity of single-celled organisms evolved. Concept: Analyze how increasingly complex multicellular organisms evolved once cells with nuclei developed. Concept: Describe how mutations in sex cells may be passed on to successive generations and that the resulting phonotype may help, harm, or have little or no effect on the offspring’s success in its environment. Lesson Essential Questions: What is a theory about the history of life on earth? Lesson Essential Questions: How did multicellular organisms develop from prokaryotes? Lesson Essential Questions: How are traits, good/bad/indifferent, passed on? Vocabulary: Vocabulary: Vocabulary: Covered in previous sections Covered in previous sections Covered in previous sections Concept: Describe the relationship between environmental changes and changes in the gene pool of a population. Lesson Essential Questions: How does the environment affect the gene pool of a population? Vocabulary: Gene Pool Allele Frequency Board Approval: April 19, 2011 — 1— EAST PENNSBORO AREA SCHOOL DISTRICT Unit: COURSE: Evolution — Natural Selection Days: 11 208 Applied Biology Subject(s): Science Grade(s): Key Learning(s): 3.1.10.C1 Explain the mechanisms of biological evolution. 10 , 11 Instructional Tools: Unit Essential Question(s): What are the mechanisms that drive biological evolution? Concept: Describe species as reproductively distinct groups of organisms. Concept: Analyze the role that geographic isolation can play in speciation. Concept: Explain how evolution through natural selection can result in changes in biodiversity through the increase or decrease of genetic diversity within a population. Lesson Essential Questions: How are future generations of the same species ensured? Lesson Essential Questions: How does geographic isolation impact speciation? Lesson Essential Questions: How does natural selection impact biodiversity? Vocabulary: Evolution Fossils Adaptation Vocabulary: Geographic Isolation Adaptation Fitness Natural Selection Biogeography Vocabulary: Darwin Natural Selection Lamarck Artificial Selection Concept: Describe how the degree of kinship between species can be inferred from the similarity in their DNA sequences. Lesson Essential Questions: How can DNA show the relationships between different species? Board Approval: April 19, 2011 — 2— EAST PENNSBORO AREA SCHOOL DISTRICT Unit: COURSE: Genetics — Biotechnology Days: 9 208 Applied Biology Subject(s): Science Grade(s): 10 , 11 Key Learning(s): Instructional Tools: 3.1.10.B4 – Explain how genetic technologies have impacted the field of medicine, forensics, and agriculture. Unit Essential Question(s): How has genetic engineering impacted medicine, forensics, and agriculture? Concept: Concept: Concept: Explain how genetic technologies have impacted the field of medicine, forensics, and agriculture. Same Same Lesson Essential Questions: Lesson Essential Questions: Lesson Essential Questions: How has the improved technologies in genetics impacted the field of medicine? How has the improved technologies in genetics impacted the field of forensics? How has the improved technologies in genetics impacted the field of agriculture? Vocabulary: Vocabulary: Vocabulary: PCR Recombinant DNa Splamids Transgenic Clones Gene Therapy DNA Fingerprinting Forensics DNA Microarray From previous sections. Board Approval: April 19, 2011 — 3— EAST PENNSBORO AREA SCHOOL DISTRICT Unit: COURSE: Genetics — Heredity Days: 24 208 Applied Biology Subject(s): Science Grade(s): 10, 11 Key Learning(s): 3.1.10.B1 Describe how genetic information in inherited and expressed. Instructional Tools: Unit Essential Question(s): How are traits passed from generation to generation? Concept: Explain that the information passed from parents to offspring is transmitted by means of genes with are coded in DNA molecules. Concept: Explain the basic process of DNA replication. Concept: Describe the basic processes of transcription and translation. Lesson Essential Questions: How do offspring get their characteristics and traits from the previous generations? Vocabulary: Lesson Essential Questions: How do new cells get a complete set of DNA for function properly? Lesson Essential Questions: How do transcription and translation impact the function of the cell? Vocabulary: Vocabulary: Concept: Explain how crossing over, jumping genes, and deletion and duplication of genes results in genetic variation. Concept: Explain how mutations can alter genetic information and the possible consequences on resultant cells. Lesson Essential Questions: What happens if the DNA is changed or mutated? Lesson Essential Questions: What are the effects of the mutations? Vocabulary: Vocabulary: DNA Trait Punnett Square Phenotype Genotype Probability Genes P1 Generation F1 Generation F2 Generation Mutations Gene Mutations Chromosomal Mutations Deletions Insertions Translocations Inversions Point Mutations Replication Replication Forks h-bonds Enzymes Nucleotides Phosphates Nitrogen Bases Sugars Double Helix Transcription Translation Mrna tRNA rRNA Codons Anticodons Triplets Complementary Base Pairing Genetic Diseases Syndromes Board Approval: April 19, 2011 — 4— EAST PENNSBORO AREA SCHOOL DISTRICT COURSE: 208 Applied Biology Unit: Genetics — Molecular Basis for Life Subject(s): Science Days: 20 Grade(s): 10, 11 Key Learning(s): Instructional Tools: 3.1.10.B3 – Describe the basic structure of DNA and its function in genetic inheritance AND describe the role of DNA in protein synthesis as it relates to gene expression. Unit Essential Question(s): What is the structure and function of DNA and what role does it play in protein synthesis? Concept: Describe the basic structure of DNA, including the role of hydrogen bonding. Concept: Explain how the process of DNA replication results in the transmission and conservation of the genetic code. Concept: Describe how transcription and translation result in gene expression. Lesson Essential Questions: What are the components of DNA and how are they arranged? Lesson Essential Questions: What is the process and purpose of replication? Lesson Essential Questions: How do transcription and translation relate to gene expression? Vocabulary: Vocabulary: Vocabulary: Nucleotide Nitrogen Bases Complementary Base Pairing Hydrogen Bonding Adenine Thymine Cytosine Guanine Double Helix Replication Replication Forks Enzymes Triplets Transcription Codon Uracil Translation Anti-Codon Mrna tRNA rRNA Concept: Differentiate among the end products of replication, transcription, and translation. Concept: Cite evidence to support that the genetic code is universal. Concept: Differentiate between the products of transcription and translation and how they are created. Lesson Essential Questions: What are the products of replication, transcription, and translation? Lesson Essential Questions: How do we know that the genetic code is universal? Lesson Essential Questions: What are the processes of transcription and translation and how do they work together to make proteins? Vocabulary: Proteins mRNA Vocabulary: Covered in previous section. Vocabulary: tRNA mRNA rRNA Polymerase Transcription Translation Board Approval: April 19, 2011 — 5— EAST PENNSBORO AREA SCHOOL DISTRICT Unit: COURSE: Genetics — Reproduction Days: 9 208 Applied Biology Subject(s): Science Grade(s): 10, 11 Key Learning(s): Instructional Tools: 3.1.10.B2 – Explain the process of meiosis resulting in the formation of gametes. Compare and contrast mitosis and meiosis. Unit Essential Question(s): How are gametes formed and how do they compare to somatic cells? Concept: Concept: Concept: Describe how the process of meiosis results in the formation of haploid gametes and analyze the importance of meiosis in sexual reproduction. Compare and contrast the function of mitosis and meiosis. Illustrate that the sorting and recombining of genes is sexual reproduction results in a great variety of possible gene combinations in offspring. Lesson Essential Questions: Lesson Essential Questions: Lesson Essential Questions: What is the purpose and products of meiosis? What are the differences between mitosis and meiosis? What increases genetic variability and how is that a benefit for living things? Vocabulary: Vocabulary: Vocabulary: Meiosis Haploid Diploid Gametes Zygote Reduction Division Meiosis I Meiosis II Covered in a previous section. Covered in a previous section. Board Approval: April 19, 2011 — 6— EAST PENNSBORO AREA SCHOOL DISTRICT Unit: COURSE: 208 Organisms and Cells — Cell Cycles Days: 16 Applied Biology Subject(s): Science Grade(s): 10, 11 Key Learning(s): Describe the cell cycles and the significance and process of mitosis. Instructional Tools: Unit Essential Question(s): What is the cell cycle and why is it important? Concept: Summarize the stages of the cell cycle. Lesson Essential Questions: What are the stages of the cell cycle and their associated structures? Vocabulary: Mitosis Cycle Interphase Metaphase Prophase Telephase Anaphase Poles Spindle Fibers Furrow Microfilament Concept: Examine how interactions among the different molecules in the cell cause the distinct stages of the cell cycle which can also be influenced by other signaling molecules. Lesson Essential Questions: What role do contact inhibition and growth factors have on the cell cycle? Vocabulary: Cell Cycle Contact Inhibition Growth Factors Concept: Explain the role of mitosis in the formation of new cells and its importance in maintaining chromosome number during asexual reproduction. Lesson Essential Questions: How is mitosis regulated to ensure the correct chromosome number during asexual reproduction? Vocabulary: Asexual Reproduction Contact Inhibition Growth Factors Cancer Carcinogen Malignant Tumor Benign Concept: Compare and contrast a virus and a cell. Relate the stages of viral cycles to the cell cycle. Board Approval: April 19, 2011 — 7— EAST PENNSBORO AREA SCHOOL DISTRICT COURSE: Unit: Organisms and Cells — Common Characteristics of Life 208 Applied Biology Subject(s): Science Grade(s): 10, 11 Days: 11 Key Learning(s): 3.1.10.A1 Instructional Tools: All organisms share common characteristics of life. Unit Essential Question(s): What are the characteristics all living things share? Concept: Explain the characteristics of life common to all organisms. Concept: Explain the characteristics of life common to all organisms. Concept: Explain the characteristics of life common to all organisms. Lesson Essential Questions: What are the characteristics of all living things? Lesson Essential Questions: What structures do prokaryotic and eukaryotic cells have in common? Lesson Essential Questions: Why do prokaryotic and eukaryotic cells have similar structures? Vocabulary: DNA Stimulus Homeostasis Metabolism Biology Biosphere Vocabulary: Mitochondria Vacuoles Cell Membrane Nucleus Lysosomes Vesicles RER SER Cell Wall Chloroplast Cytoplasm Cytoskeleton Ribosome Cell Centrioles Golgi Bodies Organelles Vocabulary: Cell Theory Prokaryotic Eukaryotic Board Approval: April 19, 2011 — 8— EAST PENNSBORO AREA SCHOOL DISTRICT Unit: COURSE: Organisms and Cells — Energy Flow Days: 26 208 Applied Biology Subject(s): Science Grade(s): 10, 11 Key Learning(s): Instructional Tools: 3.1.10.A2: Explain cell processes in terms of chemical reactions and energy changes. Unit Essential Question(s): How do living things obtain energy? Concept: Identify initial reactants, final products, and general purposes of photosynthesis and cellular respiration. Lesson Essential Questions: What are the reactants and products in photosynthesis and respiration and why are those reactions critical to life? Vocabulary: Concept: Explain the important role of ATP in cell metabolism. Concept: Describe the relationship between photosynthesis and cellular respiration in photosynthetic organisms. Lesson Essential Questions: What is ATP and how is it used in cell metabolism? Lesson Essential Questions: How does a photosynthetic organism use both photosynthesis and cellular respiration? Vocabulary: Vocabulary: Concept: Explain why many biological macromolecules such as ATP and lipids contain high energy bonds. Lesson Essential Questions: Where does the energy from ATP and lipids come from? Concept: Explain the importance of enzymes as catalysts in cell reactions. Concept: Identify how factors such as pH and temperature may affect enzyme function. Lesson Essential Questions: How do enzymes help cells use energy efficiently? Lesson Essential Questions: What factors affect how enzymes work? Vocabulary: Vocabulary: Vocabulary: ATP Lipids Enzymes Proteins Catalyst Substrate Active Site Ph Temperature Buffers Photosynthesis Cellular Respiration Reactants Products Chemical Equations ATP Metabolism Cellular Respiration Aerobic Anaerobic Glycolysis NAD+ Kreb’s Cycle Matrix Fermentation ATP Heterotroph Autotroph Photosynthesis Thylakoid Stroma NADP Light Dependent rxn Light Independent rxn Photosystem ETS Board Approval: April 19, 2011 — 9— EAST PENNSBORO AREA SCHOOL DISTRICT Unit: COURSE: Organisms and Cells — Form and Function Days: 17 208 Applied Biology Subject(s): Science Grade(s): 10, 11 Key Learning(s): 3.1.10. A5 Relate life processes to sub-cellular and cellular structures to their function. Instructional Tools: Unit Essential Question(s): How do the organelles function and work together to maintain homeostasis in cells? Concept: Relate the structure of cell organelles to their function. Concept: Explain the role of water in cell metabolism. Concept: Explain how the cell membrane functions as a regulatory structure and protective barrier for the cell. Lesson Essential Questions: What are the cell structures and their functions? Lesson Essential Questions: Why is water so critical to the metabolism of living things? Vocabulary: Mitochondria Lysosomes RER SER Nucleus Cell Membrane Cell Wall Chloroplast Golgi Bodies Vacuole Vesicle Vocabulary: Solution Solute Solvent Ph Cohesion Adhesion Polarity Lesson Essential Questions: How is the cell membrane considered a regulatory structure and a protective barrier? Vocabulary: Selectively Permeable Hydrophobic Hydrophilic Carrier Proteins Pores Phospholipid Fluid Mosaic Model Phospholipid Bilayer Concept: Describe transport mechanisms across the plasma membrane. Lesson Essential Questions: How do molecules move across the cell membrane? Vocabulary: Active Transport Passive Transport Facilitated Diffusion Homeostasis Board Approval: April 19, 2011 — 10 — EAST PENNSBORO AREA SCHOOL DISTRICT Unit: COURSE: Organisms and Cells — Life Cycles Days: 208 Applied Biology Subject(s): Science Grade(s): 10, 11 Key Learning(s): Instructional Tools: 3.1.10.A3: Compare and contrast the life cycles of single celled organisms, multi-celled organisms and viruses. Unit Essential Question(s): How do the life cycles of single-celled organisms, multi-celled organisms, and viruses compare? Concept: Concept: Concept: All organisms begin their life cycles as a virus or a single cell and some then develop into multi-celled organisms. All organisms begin their life cycles as a virus or a single cell and some then develop into multi-celled organisms. All organisms begin their life cycles as a virus or a single cell and some then develop into multi-celled organisms. Lesson Essential Questions: What is the life cycle of a singlecelled organism? Lesson Essential Questions: What is the life cycle of a multicelled organism? Lesson Essential Questions: What is the life cycle of a virus? Vocabulary: Vocabulary: Cell Division Mitosis Asexual Reproduction Sexual Reproduction Chromosome Cell Cycle Interphase Cytokinesis Chromatid Centromere Apoptosis Vocabulary: Capsid Lysogenic Infection Lytic Infection Envelope Board Approval: April 19, 2011 — 11 — EAST PENNSBORO AREA SCHOOL DISTRICT Unit: COURSE: Organisms and Cells — Molecular Basis of Life Days: 16 208 Applied Biology Subject(s): Science Grade(s): 10, 11 Key Learning(s): Instructional Tools: 3.1.10. A7 – Describe the relationship between the structure of organic molecules and the function they serve in living organisms. Unit Essential Question(s): What is the structure and function of organic compounds in and needed by living things? Concept: Concept: Concept: Analyze the importance of carbon to the structure of biological macromolecules Compare and contrast the functions and structures of proteins, lipids, carbohydrates, and nucleic acids. Explain the consequences of extreme changes in pH and temperature on cell proteins. Lesson Essential Questions: Lesson Essential Questions: Lesson Essential Questions: How can carbon bond so many different ways? What are the structure and functions of each of the macromolecules? How do pH and temperature effect the proteins in the cell? Vocabulary: Carbohydrates Lipids Proteins Nucleic Acids Covalent Bonds Ionic Bonds Ions Vocabulary: Monomers Polymers Amino Acids Monosaccharides Disaccharides Polysaccharides Nucleotides Glycerol Fatty Acids Non-Polar Vocabulary: Enzymes Catalysts Ph Temperature Denature Board Approval: April 19, 2011 — 12 — EAST PENNSBORO AREA SCHOOL DISTRICT Unit: Organisms and Cells — Organization Days: 6 COURSE: Subject(s): Science Grade(s): 10, 11 Key Learning(s): 3.1.10. A6: 208 Applied Biology Instructional Tools: Identify the advantages of multi-cellularity in organisms. Unit Essential Question(s): How do cells differentiate and why is this an advantage? Concept: Explain how cells differentiate in multicellular organisms. Lesson Essential Questions: How the cells know which type to become in a multicellular organism? Vocabulary: Multipotent Totipotent Cell Differentiation Pluripotent Growth Factors Embryo Stem Cell Board Approval: April 19, 2011 — 13 —