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GLOSSARY TERMS This glossary contains explanations of certain technical terms used in this prospectus. Such terminology and meanings may not correspond to standard industry meanings or usages of those terms. “alexin” a complex system of protein found in normal blood plasma that combines with antibodies to destroy pathogenic bacteria and other foreign cells. It is also known as complement “amylase” a group of enzymes that are present in saliva, pancreatic juice, and parts of plants and catalyse the hydrolysis of starch to sugar to produce carbohydrate derivatives “antigen” substances that can induce an organism to produce humoral antibody and cellular immunity response, and could also take part in specific recombination reaction outside the human body with antibodies and sensitised lymphocytes “AIDS” Acquired Immune Deficiency Syndrome “BCG vaccine” Bacillus Calmette-Guérin, a vaccine for tuberculosis “biochemical diagnostic reagent(s)” diagnostic reagents based on the action principle of biochemical reaction “contemporary biological medicine” an industry represented by recombinant protein and monoclonal antibody gene engineering technologies, and based on contemporary biological technologies “diagnostic reagent(s)” reagents whose main or only purpose is to provide the following information: 1) physical or pathological status; 2) congenital abnormalities status; 3) definite safety and the compatibility with possible receiver; 4) supervision of the therapy measures “DNA” abbreviation of Deoxyribonucleic Acid, which is a main component of chromosome. DNA has a double helix structure “Double Helix” the DNA structure model pronounced by James Watson and Francis Crick in 1953, which consists of two reverse-parallel nucleotide acid chains intertwined around the same central axis “DPT vaccine” Diptheria, Pertussis, Tetanus vaccines “ELISA” abbreviation of “Enzyme Linked Immunosorbent Assay” “enzyme” protein or RNA produced out of living cells, which possesses catalytic activity - 28 - GLOSSARY TERMS “fibrin” the protein responsible for the clotting of blood. It is a fibrillar protein that spontaneously polymerises to form a mesh that covers a wound “fibrinogen” protein in the blood plasma that is essential for the coagulation of blood and is converted to fibrin by thrombin and ionized calcium “GDP” abbreviation of “Gross Domestic Product” “Gene Engineering” molecular engineering to design and process molecules which carry genetic information, including gene recombination, clone and representation “glycoprotein” any of a group of conjugated proteins that contain a carbohydrate as the nonprotein component “GMP” Good Manufacturing Practice, being the guideline and regulations issued pursuant to the PRC laws by SFDA in respect of certain quality standards to be adopted in the pharmaceutical industry in the PRC “immuno diagnostic reagent(s)” diagnostic reagents based on the action principle of immunity antigen reaction and immunity antibody reaction “Immunoglobulin” or “Ig” any of a group of large glycoproteins that are secreted by plasma cells and that function as antibodies in the immune response by binding with specific antigens. There are five classes of immunoglobulins: IgA, IgD, IgE, IgG, and IgM “in-vitro diagnostic reagent(s)” diagnostic reagents used for examination outside the human body of samples taken from inside the body “in-vivo diagnostic reagent(s)” diagnostic reagents applicable directly inside the human body to check the physical or pathological status “injection” biological products produced out of viruses, rickettsias or helicoids for immunoprophylaxis and therapy “ISO9001” a series of quality assurance systems set up by International Organization for Standardization, which defines the requests for quality control systems, including the quality assurance mode of development and design, manufacture, equipping, installation and service - 29 - GLOSSARY TERMS “Lumbrokinase” a category of fibrin hydrolase whose molecular weight ranges from 21,000 to 65,000, separated from a specific species of earthworm using contemporary biochemical technologies “monoclonal antibody” anti-single-epitope highly specific antibodies cultured out of monoclonal B cells and myeloma cells “nucleic acid (Gene)” an integral segment required to form an encrypted multi-peptide linkage or functional RNA “pathogenic” originating or producing disease “plasma” the clear, yellowish fluid portion of blood, lymph, or intra-muscular fluid in which cells are suspended “protein” the most important category of macromolecule substances composed mainly of amino acid inside an organism “pulmonary embolism” embolism of a pulmonary artery or one of its branches that is produced by foreign matter and most often a blood clot originating in a vein of the leg or pelvis and that is marked by labored breathing, chest pain, fainting, rapid heart rate, cyanosis, shock, and sometimes death “RNA” abbreviation for ribonucleic acid, which is a nucleic acid polymer consisting of covalently bound nucleotides. RNA serves as the template for translation of genes into proteins, transferring amino acids to the ribosome to form proteins, and also translating the transcript into proteins “SARS” abbreviation of “Severe Acute Respiratory Syndrome” “STD” sexually transmitted disease(s) “serum” blood solution of which hemocytes and fibrins have been removed by means such method as centrifugal processing “serum transfer receptor (sTfR)” serum transferrin receptor (sTfR) is a marker of iron that is available for the formation of red blood cell “thrombin” an enzyme in blood that facilitates blood clotting “thrombophlebitis” inflammation of a vein caused by or associated with the formation of a blood clot - 30 - GLOSSARY TERMS “thrombosis” the formation, presence, or development of a thrombus, a fibrinous clot formed in a blood vessel or in a chamber of the heart “thyroxine” a substance secreted by the thyroid gland “Toxin” toxic products of bacteria, including exogenous toxin and endotoxin - 31 -