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The Endocrine System Endocrine System • A set of glands that produce hormones-- chemical messengers that circulate in the blood Hormone • Chemical messengers produced by the endocrine glands and circulated in the blood • Similar to neurotransmitters in that they are also messengers • Slower communication system, but with longer lasting effects Endocrine System Hypothalamus • Brain region that controls the pituitary gland • Controls homeostasis – the bodies ability to remain at a status quo level Pituitary Gland • The endocrine system’s gland that controls the other endocrine glands • Called the “master gland” • Located at the base of the brain and connects to the hypothalamus • Controls thirst by controlling the amount of water in the body’s cells • Controls female contractions, and tells the mammary glands to produce milk for newborns • May control grooming habits, companionship, and sexual behavior • Controls the flow of the human growth hormones – dwarfism and gigantism Thyroid Gland • Endocrine gland that helps regulate the energy level in the body • Located in the neck • Controls body temperature • Controls metabolism – our body’s ability to transform the food we eat into usable energy Adrenal Gland • Endocrine glands that help to arouse the body in times of stress • Located just above the kidneys • Release epinephrine (adrenaline) and norepinephrine (noradrenaline) • Increase heart rate, blood pressure, and blood sugar Pancreatic Gland • Regulates the level of blood sugar in the blood by insulin • Insulin is needed in the body to break down sugars in the body Sex Glands • Ovaries (females) and testes (males) are the glands that influence emotion and physical development. • Testosterone – primary male hormone • Estrogen – primary female hormone • Males and females have both estrogen and testosterone in their systems. Gonads (sex organs) • Testicles – release androgens (male hormones) • Ovaries – release estrogens (female hormones) • The presence of these chemicals influence male and female reproductive characteristics. Maintaining Homeostasis • Homeostasis is the maintenance of a stable internal state within an organism. • Organisms detect changes in their environment and respond to these changes in a variety of ways. • A feedback mechanism occurs when the level of one substance influences the level of another substance or activity of another organ. Feedback Mechanisms Three parts of the mechanism – Sensor – something that can detect a change • Ex. Structures in the brain detect changes in CO2 levels – Control Unit – something that knows what the correct level should be • Ex. Information in the brain is preset for the correct CO2 level – Effector – something to take the instructions and make changes • Ex. Muscles in the chest used for breathing Feedback Mechanisms • Positive feedback - designed to accelerate or enhance the output created by a stimulus that has already been activated. • Designed to push levels out of normal ranges. • Example is the release of oxytocin to intensify the contractions that take place during childbirth. – The more oxytocin, the greater and more frequent the contractions, which in turn produces more oxytocin Feedback Mechanisms • Negative feedback – process in which a stimulus produces a response that opposes the original stimulus. • Ex. Blood sugar regulation – An increase in blood sugar level triggers the release of the hormone insulin by the pancreas – the hormone insulin lowers blood sugar level restoring the body to its original blood glucose level in two major ways: • it increases the ability of body cells to take in glucose from the blood • it converts blood glucose to the compound glycogen -- this compound is also called animal starch and is stored in our liver and muscles – A decrease in blood sugar levels triggers the release of the hormone glucagon by the pancreas • It causes the liver to release glucose into the blood to regulate blood sugar levels Endocrine Disorders Diabetes • interruption of the feedback system that controls blood sugar. • Too little insulin = buildup of sugar in the blood • the kidneys use a lot more water to flush it out of the body. • extra water comes from surrounding cells, which in turn dehydrates them – leaves the cells vulnerable to infection and poisons. • Type I – born with it – Controlled by insulin injections • Type II – acquired – Usually occurs in older people – May be controlled with diet Endocrine Disorders – Hyperactive thyroid- Behaviors may include excitability, insomnia, ADD, agitation, difficulty focusing – Hypoactive thyroid - Behaviors may include sleepiness, reduced muscle tone, overweight – Hypoglycemia - Too much insulin in the body devours all of the sugar in the blood. May appear sluggish and inattentive.