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University of Central Lancashire Research Project/Studentship Description Project ref: RS/15/36 Closing Date: 02/06/2016 Proposed Director of Studies School Contact Details Programme Duration of Studentship Hours (Full or Part Time) Dr Robert B. Smith Physical Sciences and Computing 01772-894384 ([email protected]) MSc (by Research) One Year Full Time Tuition Fees Maintenance Grant Any Entry Requirements (e.g. 2:1 classification/restricted residences only) Paid at Home/EU levels £11,000 UK Bachelor Honours degree at 2:1 level or above (or equivalent qualification) in Chemistry or a closely related discipline and a 2:1 or above grade for the final year laboratory based dissertation preferably within the area of organic synthesis or medicinal chemistry. to UK Project Title Photoactive self-disinfection bandages towards next generation infection control Project Description Infection control in the 21st century is problematic, particularly from the point of view of microbial drug resistance. Given the problem of increasing antimicrobial drug resistance and the paucity of new agents, it is sensible to consider alternative approaches to infection control especially towards wound management. One major problem is infections around open wounds, either through postoperative surgical procedures or burns/scalds. The bacterial pathogens that primarily infect burns are methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa, and Klebsiella species. In addition to this, burn wounds are commonly infected with a number of fungal species including Candida albicans. This project seeks to generate a technology capable of maintaining a clean wound environment, through touch of the button disinfection (without the need for administration of antibiotics or skin disinfectants capable of causing pain or irritation), by using light-activated photoantimicrobials. These are chemicals that absorb light energy and use this to power chemical reactions in their immediate environment, usually via the production of reactive oxygen species (ROS), which is microbicidal upon illumination. Research Student Specification Studentship Ref Number RS/15/36 Project Title: Photoactive self-disinfection bandages towards next generation infection control School Physical Sciences and Computing Contact: Dr Robert B. Smith Tel 01772 894384 email [email protected] Attributes Education/Qualifications Closing Date: Essential UK Bachelor honours degree at 2:1 or above classification(or equivalent qualification), preferably in a chemistry discipline 02/06/2016 Desirable Measured By Click here to enter text. Application Click here to enter text. Application and Interview A 2:1 grade (or above) for final year laboratory based dissertation preferably within the area of organic synthesis or medicinal chemistry Experience Experience in organic synthesis/medicinal chemistry via dissertation/ research project Skills/Abilities Excellent oral and written communication skills Knowledge and understanding of scientific methods underpinning research Application and Interview Click here to enter text. Application and Interview Enthusiastic Time management skills IT literate (Microsoft Word, Excel, Qualitative Analysis software, Statistical software) Personal Details Interest, in general, in organic synthesis, medicinal chemistry and drug discovery