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Resistance Publications from July 2008 to September 2008 Title Author Journal 1) Origin and evolutionary history of HIV-1 subtype C in Brazil. Bello, Gonzalo AIDS - October 1, 2008, Volume 22, Issue 15 2) On the origin of HIV-1 subtype C in South America. Fontella, Rachel AIDS - October 1, 2008, Volume 22, Issue 15 Bénédicte Roquebert AIDS - October 1, 2008, Volume 22, Issue 15 (Correspondence, no abstract) 3) Selection of the Q148R integrase inhibitor resistance mutation in a failing raltegravir containing regimen. 4) Pattern and impact of emerging resistance mutations in treatment experienced patients failing darunavir-containing regimen. Delaugerre, Constance AIDS - September 12, 2008, Volume 22, Issue 14 5) The epidemic origin and molecular properties of B': a founder strain of the HIV1 transmission in Asia. Deng, Xiang AIDS - September 12, 2008, Volume 22, Issue 14 6) Probing the sequence space available for HIV-1 evolution. ter Brake, Olivier AIDS - September 12, 2008, Volume 22, Issue 14 7) Clade-specific HIV-1 integrase polymorphisms do not reduce raltegravir and elvitegravir phenotypic susceptibility. Van Baelen AIDS - September 12, 2008, Volume 22, Issue 14 8) Correlation between genotypic predictions based on V3 sequences and phenotypic determination of HIV-1 tropism. Raymond, Stephanie AIDS - September 12, 2008, Volume 22, Issue 14 9) Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection. Brumme, Zabrina L AIDS - July 11, 2008 Volume 22, Issue 11 10) Early virological suppression with threeclass antiretroviral therapy in HIV-infected African infants. Prendergast, Andrew AIDS - July 11, 2008, Volume 22, Issue 11 11) Transmission of HIV-1 minority-resistant variants and response to first-line antiretroviral therapy. Peuchant, Olivia AIDS - July 31, 2008, Volume 22, Issue 12 12) Interplay of Reverse Transcriptase Inhibitor Therapy and Gag p6 Diversity in HIV Type 1 Subtype G and CRF02_AG Akinyemi I. Ojesina AIDS Research and Human Retroviruses, September 2008, Volume 24, Issue 9 13) Analysis of Nevirapine Resistance Mutations in Cloned HIV Type 1 Variants from HIV-Infected Ugandan Infants Using a Single-Step Amplification-Sequencing Method (AmpliSeq) William Ian Towler AIDS Research and Human Retroviruses, September 2008, Volume 24, Issue 9 14) Examination of a Second Region of the HIV Type 1 Genome Reveals Additional Cases of Superinfection Anne Piantadosi AIDS Research and Human Retroviruses, September 2008, Volume 24, Issue 9 15) Analysis of Near Full-Length Genomic Sequences of Drug-Resistant HIV-1 Spreading among Therapy-Naïve Individuals in Nagoya, Japan: Amino Acid Mutations Associated with Viral Replication Activity Shiro Ibe AIDS Research and Human Retroviruses, August 2008, Volume 24, Issue 8 16) Molecular Epidemiology Demonstrated Three Emerging Clusters of Human Immunodeficiency Virus Type 1 Subtype B Infection in Hong Kong AIDS Research and Human Retroviruses, July 2008, Volume 24, Issue 7 Tommy W.C. Leung 17) Use of Tissue Culture Cell Lines to Evaluate HIV Antiviral Resistance Halina Krowicka AIDS Research and Human Retroviruses, July 2008, Volume 24, Issue 7 18) Short Communication: Profiling ResistanceRelated Mutations in the Protease Region of the pol Gene: Single Genome Sequencing of HIV in Plasma and Peripheral Blood Mononuclear Cells Ana Paula Guimaraes AIDS Research and Human Retroviruses, July 2008, Volume 24, Issue 7 19) Mechanisms of Human Immunodeficiency Virus Type 1 Concerted Integration Related to Strand Transfer Inhibition and Drug Resistance Jacob A. Zahm Antimicrobial Agents and Chemotherapy, September 2008, Volume 52, Issue 9 20) Pharmacokinetics of High-Dose LopinavirRitonavir with and without Saquinavir or Nonnucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus-Infected Pediatric and Adolescent Patients Previously Treated with Protease Inhibitors Brian L. Robbins Antimicrobial Agents and Chemotherapy, September 2008, Volume 52, Issue 9 Anne-Genevieve Marcelin Antimicrobial Agents and Chemotherapy, September 2008, Volume 52, Issue 9 21) Tipranavir-Ritonavir Genotypic Resistance Score in Protease Inhibitor-Experienced Patients 22) Population trends in the prevalence and patterns of protease resistance related to exposure to unboosted and boosted protease inhibitors The UK Collaborative Group on HIV Drug Resistance and the UK Collaborative HIV Cohort Study Antiviral Therapy, Volume 13, Issue 6 23) Effect of tenofovir subtraction on HIV plasma viraemia, CD4+ T-cell count and resistance in a patient with baseline K65R and M184V mutations Ricky Hsu Antiviral Therapy, Volume 13, Issue 5 24) The status of HIV-1 resistance to antiretroviral drugs in sub-Saharan Africa Raph L Hamers Antiviral Therapy, Volume 13, Issue 5 25) Comparison of raltegravir and elvitegravir on HIV-1 integrase catalytic reactions and on a series of drug-resistant integrase mutants. Marinello, J Biochemistry. September 9, 2008, Volume 47, Issue 36 26) Emergence of Drug Resistance in HIV Type 1–Infected Patients after Receipt of FirstLine Highly Active Antiretroviral Therapy: A Systematic Review of Clinical Trials Ravindra Gupta Clinical Infectious Diseases, September 1, 2008, Volume 47, Issue 5 27) Detection of Nonnucleoside ReverseTranscriptase Inhibitor–Resistant HIV-1 after Discontinuation of Virologically Suppressive Antiretroviral Therapy C. Bradley Hare Clinical Infectious Diseases, August 1, 2008, Volume 47, Issue 3 28) Antiretroviral Drug Resistance Testing in Adult HIV-1 Infection: 2008 Recommendations of an International AIDS Society–USA Panel Martin S. Hirsch Clinical Infectious Diseases, July 15, 2008, Volume 47, Issue 2 29) Maraviroc: The First of a New Class of Antiretroviral Agents Clinical Infectious Diseases, July 15, 2008, Volume 47, Issue 2 Rodger D. MacArthur 30) Drug resistance profiles for the HIV integrase gene in patients failing raltegravir salvage therapy. Charpentier, C HIV Medicine (EPub ahead of print) 31) Impact of reverse transcriptase resistance on the efficacy of TMC125 (etravirine) with two nucleoside reverse transcriptase inhibitors in protease inhibitor-naïve, nonnucleoside reverse transcriptase inhibitor-experienced patients: study TMC125-C227. HIV Medicine (Epub ahead of print) Ruxrungtham, K 32) Secure antiretroviral therapy delivery in a resource-limited setting: streamlined to minimize drug resistance and expense D Kitkungvan HIV Medicine, September 2008, Volume 9, Issue 8 33) Prediction of phenotypic susceptibility to antiretroviral drugs using physiochemical properties of the primary enzymatic structure combined with artificial neural networks J Kjær HIV Medicine, September 2008, Volume 9, Issue 8 34) New mutations associated with resistance not detected following zidovudine monotherapy in pregnancy when used in accordance with British HIV Association guidelines P Read HIV Medicine, August 2008, Volume 9, Issue 7 35) RNA amplification of the HIV-1 Pol and env regions on dried serum and plasma spots R Dachraoui HIV Medicine, August 2008, Volume 9, Issue 7 36) The Impact of Different Definitions on the Estimated Rate of Transmitted HIV Drug Resistance in the United Kingdom. JAIDS (Epub ahead of print) Green, H 37) HIV Drug Resistance Pattern Among HAART-Exposed Patients With Suboptimal Virological Response in Ouagadougou, Burkina Faso. Tebit, Denis JAIDS, 1 September 2008, Volume 49, Issue 1 38) Phylogenetic Investigation of Transmission Pathways of Drug-Resistant HIV-1 Utilizing Pol Sequences Derived From Resistance Genotyping. Kaye, Matthew JAIDS, 1 September 2008, Volume 49, Issue 1 39) Letters to the Editor: Emergence of Resistance Mutations Preceding Virologic Failure in Patients Receiving Antiretroviral Therapy. Ricardo S Diaz JAIDS, 1 September 2008, Volume 49, Issue 1 40) In Vitro Characterization of MultidrugResistant HIV-1 Isolates From a Recently Infected Patient Associated With Dual Tropism and Rapid Disease Progression. Mohri, Hiroshi JAIDS 15 Aug 2008, Volume 48, Issue 5 41) Viral Dynamics and In Vivo Fitness of HIV-1 in the Presence and Absence of Enfuvirtide. Marconi, Vincent JAIDS, 15 Aug 2008, Volume 48, Issue 5 42) High Prevalence of Unique Recombinant Forms of HIV-1 in Ghana: Molecular Epidemiology From an Antiretroviral Resistance Study. JAIDS, 15 Aug 2008, Volume 48, Issue 5 Delgado, Elena 43) Viral Dynamics and In Vivo Fitness of HIV-1 in the Presence and Absence of Enfuvirtide. Marconi, Vincent JAIDS, August 15, 2008, Volume 48, Issue 5 44) High prevalence of unique recombinant forms of HIV-1 in Ghana: molecular epidemiology from an antiretroviral resistance study. JAIDS, August 15, 2008, Volume 48, Issue 5 Delgado, E 45) Optimization of the Oligonucleotide Ligation Assay, a Rapid and Inexpensive Test for Detection of HIV-1 Drug Resistance Mutations, for Non-North American Variants. Beck, Ingrid JAIDS, 1 Aug 2008, Volume 48, Issue 4 46) The A62V and S68G Mutations in HIV-1 Reverse Transcriptase Partially Restore the Replication Defect Associated With the K65R Mutation. Svarovskaia, Evguenia S JAIDS, 1 Aug 2008, Volume 48, Issue 4 47) HIV-2 integrase gene polymorphism and phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitors raltegravir and elvitegravir in vitro. Roquebert, B Journal of Antimicrobial Chemotherapy (Epub ahead of print) 48) Impact of gag mutations on selection of darunavir resistance mutations in HIV-1 protease. Lambert-Niclot, S Journal of Antimicrobial Chemotherapy (Epub ahead of print) 49) Detection of low-frequency K103N mutants after unstructured discontinuation of efavirenz in the presence of the CYP2B6 516 TT polymorphism. Garcia-Diaz, A Journal of Antimicrobial Chemotherapy (Epub ahead of print) 50) Shifting paradigms: the resistance profile of etravirine Anna Maria Geretti Journal of Antimocrobial Chemotherapy, October 2008, Volume 62, Issue 4 51) Low prevalence of transmitted antiretroviral drug resistance in a large UK HIV-1 cohort Brendan A. I. Payne Journal of Antimicrobial Chemotherapy, September 2008, Volume 62, Issue 3 52) Why are there different dynamics in the selection of drug resistance in HIV and hepatitis B and C viruses? Vincent Soriano Journal of Antimicrobial Chemotherapy, July 2008, Volume 62, Issue 1 Anne Derache Journal of Antimicrobial Chemotherapy, June 13, 2008, Volume 62, Issue 3 53) Evolution of genetic diversity and drug resistance mutations in HIV-1 among untreated patients from Mali between 2005 and 2006 54) HIV-1-infected patients from the French National Observatory experiencing virological failure while receiving enfuvirtide Diane Descamps Journal of Antimicrobial Chemotherapy, June 13, 2008, Volume 62, Issue 3 55) Tipranavir resistance associated mutations in protease inhibitor-naïve patients with HIV1 subtype A/E infection. Sungkanuparph, S Journal of Clinical Virology (Epub ahead of print) 56) Foscarnet salvage therapy efficacy is associated with the presence of thymidineassociated mutations (TAMs) in HIV-infected patients Charlotte Charpentier Journal of Clinical Virology, October 2008, Volume 43, Issue 2 57) The HIV-1 protease resistance mutation I50L is associated with resistance to atazanavir and susceptibility to other protease inhibitors in multiple mutational contexts P. Sista Journal of Clinical Virology, August 2008, Volume 42, Issue 4 58) Analysis of Nevirapine (NVP) Resistance in Ugandan Infants Who Were HIV Infected Despite Receiving Single-Dose (SD) NVP versus SD NVP Plus Daily NVP Up to 6 Weeks of Age to Prevent HIV Vertical Transmission Jessica D. Church Journal of Infectious Diseases, October 1, 2008, Volume 198, Issue 7 59) Characteristics of HIV Type 1 (HIV-1) Glycoprotein 120 env Sequences in MotherInfant Pairs Infected with HIV-1 Subtype CRF01_AE Tanawan Samleerat Journal of Infectious Diseases, September 15, 2008, Volume 198, Issue 6 60) Nevirapine Resistance in Women and Infants after First versus Repeated Use of Single-Dose Nevirapine for Prevention of HIV-1 Vertical Transmission Tamara S. Flys Journal of Infectious Diseases, August 15, 2008, Volume 198, Issue 4 61) HIV-1 diversity among inmates of Italian prisons Benedetta Longo Journal of Medical Virology, October 2008, Volume 80, Issue 10 62) Antiretroviral genotypic resistance in plasma RNA and whole blood DNA in HIV-1 infected patients failing HAART Annalisa Saracino Journal of Medical Virology, October 2008, Volume 80, Issue 10 63) Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. Ren J Journal of Medicinal Chemistry, 28 August 2008, Volume 51, Issue 16 64) Mechanistic Basis of Zidovudine Hypersusceptibility and Lamivudine Resistance Conferred by the Deletion of Codon 69 in the HIV-1 Reverse Transcriptase Coding Region Mónica Kisic Journal of Molecular Biology, 3 October 2008, Volume 382, Issue 2 65) Minority HIV-1 Variants in Antiretroviral Naive Persons with Reverse Transcriptase Codon 215 Revertant Mutations. Mitsuya, Y Journal of Virology (Epub ahead of print) 66) Resistance mutations in HIV-1 integrase selected with Elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors. Goethals, O Journal of Virology (Epub ahead of print) 67) Baseline resistance of primary HIV-1 strains to the CXCR4 inhibitor AMD3100. Harrison, J E Journal of Virology (Epub ahead of print) 68) Temporal and Spatial Dynamics of Human Immunodeficiency Virus Type 1 Circulating Recombinant Forms 08_BC and 07_BC in Asia Kok Keng Tee Journal of Virology, September 2008, Volume 82, Issue 18 69) In Vivo Emergence of Vicriviroc Resistance in a Human Immunodeficiency Virus Type 1 Subtype C-Infected Subject Athe M. N. Tsibris Journal of Virology, August 2008, Volume 82, Issue 16 70) Human Immunodeficiency Virus (HIV) Type 1 Proviral Hypermutation Correlates with CD4 Count in HIV-Infected Women from Kenya Allison M. Land Journal of Virology, August 2008, Volume 82, Issue 16 71) Mechanistic Studies of a T20-Dependent Human Immunodeficiency Virus Type 1 Variant Chris Baldwin Journal of Virology, August 2008, Volume 82, Issue 15 72) Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection. Cooper, D A New England journal of Medicine, July 2008, Volume 359, Issue 4 73) Raltegravir with optimized background therapy for resistant HIV-1 infection. Steigbigel, R T New England Journal of Medicine, July 2008, Volume 359, Issue 4 74) HIV Integrase Inhibitors — Out of the Pipeline and into the Clinic Diane V. Havlir New England Journal of Medicine, July 24, 2008, Volume 359, Issue 4 75) Review of HIV antiretroviral drug resistance. Chen, T K Pediatric Infectious Disease Journal, Aug 2008, Volume 27, Issue 8 76) Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy. johnson, J A PLoS Med. 29 July 2008 Volume 5, Issue 7 77) Natural variation of HIV-1 group M integrase: inplications for a new class of antiretroviral inhibitors Rhee, Soo-Yon Retro Virology, 7th August 2008, Volume 5, Issue 74 78) New and Old Complex Recombinant HIV-1 Strains among Patients with Primary Infection in 1996-2006 in France: the French ANRS CO06 Primo Cohort Study Frange, Pierre RetroVirology, 1st August 2008, Volume 5, Issue 69 79) Drug-resistant TB and HIV in resourcelimited settings: what TB/HIV programmes can learn from each other. Tropical Medicine and International Health (Epub ahead of print) Colebunders, R