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THE CANCER COUNCIL VIC
Fellowships
Carden Fellowship
D Metcalf
Walter and Eliza Hall Institute of
Medical Research
Regulatory control of normal and leukaemic cells
$200,000
Colebatch Fellowship
K Phillips
Peter MacCallum Cancer Centre
Reducing the burden of breast cancer
$144,500
Dunlop Fellowship
G McArthur
Peter MacCallum Cancer Centre
Development of targeted therapies for cancer
$144,500
Lions Fellowship
B Anderson
Walter and Eliza Hall Institute of
Medical Research
Coeliac disease and increased risk of cancer – novel therapeutic approaches
$20,000
(approx)
Early Career Clinical Research Fellowship
K Herbert
Peter MacCallum Cancer Centre
The use of novel therapies in haematopoietic stem cell transplantation
in cancer
$50,000
Total fellowships
$559,000
Research grants
R Anderson, I Haviv, J George
Peter MacCallum Cancer Centre
Functional genomic screen for metastasis suppressor genes controlling
breast cancer metastasis to bone and lung
$100,000
Y Antill, I Winship, M Jenkins
Peter MacCallum Cancer Centre
Studies into gynaecological cancers associated with the syndrome:
Hereditary Nonpolyposis Colon Cancer
$55,025
L Bach, G Rice
Monash University
Insulin-like growth factor (IGF)-dependent and -independent actions of
IGF binding protein-6
$70,000
O Bernard
St Vincent's Institute of Medical Research
The role of LIM kinase 2 (LIMK2) in cancer metastasis
$93,500
P Bouillet, G Belz
Walter and Eliza Hall Institute
Mouse models to study the function of the BH3-only members of the
Bcl-2 family
$100,000
W Chen
Ludwig Institute for Cancer Research
Study immunodominance of natural and induced anti-NY-ESO-1 T cell
responses to optimize future cancer vaccine strategies
$70,000
C Christophi, P Angus, V Muralidharan
The University of Melbourne
The Renin Angiotensin System and colorectal liver metastases
$66,875
P Darcy, M Kershaw, J Trapani
Peter MacCallum Cancer Centre
Immunotherapy of Lewis Y+ malignancy using genetically engineered T cells
$70,000
L Ebert
Ludwig Institute for Cancer Research
The role of regulatory T cells in suppression of immune responses in cancer
vaccine recipients
$65,000
W Fairlie, D Huang
Walter and Eliza Hall Institute
Understanding apoptosis through selective targeting of pro-survival proteins
$70,000
G Fogarty (NSW), B Burmeister (QLD),
K Drummond (VIC), A Nowak (WA),
A Rezo (ACT), J Thompson (NSW),
J Simes (NSW)
Whole brain radiotherapy following local treatment of intracranial
metastases of melanoma – a randomised phase III trial
M Friedlander (NSW), P Grimison (NSW),
M Stockler (NSW), G Toner (VIC),
D Thomson (QLD), N Singhal (SA)
Accelerated first line chemotherapy for advanced germ cell tumours
$11,250
P Fuller
Prince Henry's Institute of Medical Research
Characterisation of the molecular pathogenesis of ovarian granulosa cell
tumours
$70,000
C Gargett
Monash University
Identifying markers of stem/progenitor cells in normal and malignant
endometrium
$100,000
M Gillespie
St Vincent's Institute of Medical Research
Role of parathyroid hormone-related protein in DNA repair and breast
cancer susceptibility to TRAIL-mediated apoptosis
$100,000
C Hawkins, D Ashley & H Friedman
Murdoch Childrens Institute
Factors influencing TRAIL sensitivity in ex vivo malignant glioma
$70,000
P Humbert
Peter MacCallum Cancer Centre
The role of scribble in mammalian tumour development
$68,652
B Jenkins, A Mansell, R Ferrero
Monash University
Cross-talk between cytokine and pathogen recognition receptor networks
in the pathogenesis of gastric cancer
$98,900
$8,500
R Johnstone
Peter MacCallum Cancer Centre
Mechanisms of action of histone deacetylase inhibitors: novel anti-cancer
drugs
$70,000
A Kneebone (NSW), S Williams (VIC),
G Duchesne (VIC), R Fisher (VIC),
M Frydenberg (VIC)
A phase III trial comparing adjuvant versus salvage radiotherapy for high
risk patients post radical prostatectomy
G Lindeman (Vic), G Mitchell (Vic),
A Stapleton (SA)
The University of Melbourne
Identification of men with a genetic predisposition to prostate cancer and
their clinical treatment – The IMPACT Study
$63,300
J McCluskey, Dr J Rossjohn
University of Melbourne
The structural and functional basis of tumour recognition by NKT cells
$70,000
M McKay, H Xu
Peter MacCallum Cancer Centre
Cohesin-mediated modulation of mammalian radiosensitivity
E Nice, P Gibbs, L Lipton
Ludwig Institute for Cancer Research
Development of validated biomarker assays for the early detection and
surveillance of colon cancer
R Pearson
Peter MacCallum Cancer Centre
Mechanisms of AKT3 driven malignant transformation
G Pietersz
Macfarlane Burnet Institute for
Medical Research and Public Health
Cell penetrating peptide-mediated delivery of multiple CD8 and CD4 T cell
Epitopes for breast cancer vaccines
$100,000
$100,000
$70,000
$100,000
$92,346
T Price (SA), J Harvey (QLD), N Tebbutt (VIC), Preop chemoradiotherapy&postop chemo with capecitabine & oxaliplatin
G Hruby (NSW), S Bydder (WA),
vs capecitabine alone in locally advanced rectal cancer
R Simes (NSW), J Zalcberg (VIC)
$24,500
R Ramsay, I Bertoncello, E Stanley
Peter MacCallum Cancer Centre
CSF-1 is an essential intestinal epithelial cell mitogen
$70,000
G Risbridger, S McPherson
Monash Institute of Medical Research
Early origins of prostate cancer
$66,000
S Russell, H Richardson
Peter MacCallum Cancer Centre
A new role for polarity proteins in leukemia/lymphoma
$70,000
B Sarcevic
St Vincent's Institute of Medical Research
Identification of SAP180 and RBP1 as novel CDK substrates important for
regulation of the pRb tumour suppressor
$100,000
A Shulkes, J Ischia, G Baldwin, D Bolton
University of Melbourne
ProGRP as a biomarker for prostate cancer
$100,000
M Smyth
Peter MacCallum Cancer Centre
Combined chemo-immunotherapies that eradicate established tumors
$100,000
M Southey
University of Melbourne
New gene for BRCA1-like early-onset breast cancer
$97,500
D Thomas, P Simmons
Peter MacCallum Cancer Centre
Role of WIF1 in bone development and oncogenesis
$70,000
P Thompson, B Vogelstein
Monash University
Towards selective inhibition of oncogenic forms of PI3K – a chemical
biology approach
$66,750
E Thompson, A Dobrovic, P Choong, P Hill,
M Henderson, K Pantel
University of Melbourne
Epithelial – mesenchymal interconversions in the breast cancer
metastatic cascade
$95,100
T Tiganis
Monash University
Regulation of the Src proto-oncogene
$70,000
P Vasey (NSW), M Quinn (Vic),
J Simes (NSW), M Friedlander (NSW),
M Buck (Qld), B Koczwara (SA)
Royal Women's Hospital
Carboplatin flat dosing versus intrapatient dose escalation in first line
chemotherapy of ovarian cancer
$38,000
N Wetzig (Qld), G Gill (SA), O Ung (NSW),
J Collins (Vic), D Oliver (WA)
Royal Melbourne Hospital
SNAC2: A randomised trial of extending sentinel node based management
to women with larger or multifocal breast cancers
$30,000
E Williams, K Opeskin, C Temelcos
Monash Institute of Medical Research
Mechanisms underlying prostate cancer lymph node metastasis
$70,000
L Wu
Walter and Eliza Hall Institute
Development and functional analysis of human dendritic cell subsets
$70,000
Total reseach grants
$3,091,198
Venture grants
The Venture Grants Scheme is an initiative designed to fund projects that push the conventional boundaries. Successful projects were
selected via a competitive application process and their continued funding is dependent on key milestones being met. The Cancer
Council Victoria provided seed funding and funding for future milestones is still being sought.
W Alexander, B Kile, A Strasser
Walter and Eliza Hall Institute
Scanning the genome for new drug targets in cancer
$159,562
A Brumby, P Humbert, H Richardson, I Street Drosophila as a novel tool for anti-cancer drug discovery
University of Melbourne
$44,747
R Johnstone, R Hannan,
G McArthur, R Pearson
Peter MacCallum Cancer Centre
Identification of novel breast cancer suppressor and chemotherapeutic
drug sensitivity genes using shRNA-mediated functional genomics screens
$317,000
P Rogers, R Lewis, I Svalbe, B Williams,
D Blakey
Monash University
The biological effects of synchrotron microbeam radiation therapy on
normal and tumour tissues
$129,125
J Visvader, I Street, G Lindeman, K Watson,
M Asselin-Labat
Walter and Eliza Hall Institute
Developing lead compounds to target breast cancer by specific inhibition
of the LMO4-oncogene
Total venture grants
$35,187
$685,621
Postdoctoral research fellowships
E Lee, Walter & Eliza Hall Institute of Medical Research
$63,500
M Moeller, Peter MacCallum Cancer Centre
$63,500
P Kelly, Walter & Eliza Hall Institute of Medical Research
$31,750
M van Delft, Walter & Eliza Hall Institute of Medical Research
$31,750
Two fellowships to be appointed mid-year
$64,750
Total postdoctoral research fellowships
$255,250
Postgraduate research scholarships
S Amos, Peter MacCallum Cancer Centre
F Barnett, Ludwig Institute for Cancer Research
$23,558
$2396
I Elsum, Peter MacCallum Cancer Centre
$23,150
C Fedele, Monash University
$11,987
Y Jayasinghe, Murdoch Children's Research Institute
$28,250
D Kethesparan, Monash University
$23,150
S Lee, Ludwig Institute for Cancer Research
$28,250
E Naik, Walter & Eliza Hall Institute of Medical Research
$9989
N Thomas, Monash University
$23,558
Four postgraduate scholarships to commence January 2008
$96,000
Total postgraduate research fellowship
$270,288
Vacation studentships
25 six week summer Vacation Studentships were awarded
Support for medical and scientific activities
$35,300
$309,000
Clinical research
The Cancer Council also supports clinical research via the Centre for Clinical Research in Cancer. The centre conducts
state, national and international clinical trials initiated by and endorsed by the Victorian Cooperative Oncology Group.
The Centre also administers the Cancer Trials Management Scheme, awarding grants totalling $800,000 to 20
hospital cancer clinics to assist clinicians to enrol patients in clinical trials.
$1,765,000
Cancer Control Research Institute programs
Cancer Epidemiology Centre
$3,195,000
Victorian Cancer Registry
$3,869,000
The Melbourne Collaborative Cohort Study (Health 2000)
$2,977,000
Centre for Behavioural Research in Cancer
$2,923,000
VicHealth Centre for Tobacco Control (Cancer Council Victoria contribution to VicHealth Centre)
$2,192,000
Total Cancer Control Research Institute programs
$15,156,000
TOTAL RESEARCH FUNDED
$22,126,657