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Dr Dhiraj Gupta MBBS, MD, DM, FRCP (UK) Date of Birth 08 October 1970 Sex Male Nationality British Telephone 01516001793 (Office) Email [email protected] GMC 5205561 (Full Registration) Current Appointments March 2007 till date Consultant Cardiologist / Electrophysiologist The Liverpool Heart and Chest Hospital July 2011 till date Honorary Senior Lecturer, Imperial College, London June 2012 till date Clinical Lead and Co-founder, Primary Care AF service Nov 2014 till date Medical Advisor, Atrial Fibrillation Association UK Aug 2015 till date Head, Arrhythmia Working Group, ICMS Oct 2015 till date Member of Council, British Heart Rhythm Society Nov 2015 till date Honorary Senior Lecturer, University of Liverpool Oct 2014 till date Member, Scientific Committee, Heart Rhythm Congress Brief Profile I am a consultant cardiologist/ electrophysiologist at the Liverpool Heart and Chest Hospital (LHCH) since 2007. LHCH provides a regional electrophysiology (EP) service to a population of 2.8 million, and is one of the largest cardiac centres in the United Kingdom. I am a very high volume operator in interventional EP, and have performed over 200 ablation cases annually since 2009. I am the trust lead for Left Atrial Appendage Occluder (LAAO) Service, and our hospital was one of 10 sites selected nationally for this service by the NHS England as part of the Commissioning through Evaluation (CtE) program. I proctor cardiologists nationally and internationally for LAAO implants, and I have been awarded NHS Clinical Excellence Awards in 2010, 2014 and 2015. I have held the position of Honorary Senior Lecturer at Imperial College London since 2011, and head the arrhythmia working group of the Institute of Cardiovascular Medicine and Science, a research collaboration between Royal Brompton Hospital and LHCH. I am the primary supervisor for three MD (res) students at Imperial, and also assess the progress of other Students at Imperial College working towards higher research degrees. I have examined PhD candidates for Queen Mary University, and City University, London. I am the Chief Investigator for four ablation trials (PRESSURE, SMANPAF, PRAISE, and VISTAX), and Dhiraj Gupta Mar 2017 have been successful in obtaining over £1.5 million in competitive research grants. In the past 3 years, I have authored over 15 scientific publications as senior author. I have earned repute for my expertise in treating patients suffering from Atrial Fibrillation (AF), and I work closely with the British Heart Foundation to provide education and training to their staff nationally. I am also member of the Medical Advisory Committee of the national charity, AF Association. I have been elected to the Council of British Heart Rhythm Society in Oct 2015 for a term of three years, and as a council member I help shape national guidelines and policies related to arrhythmia care. In addition to my roles as an interventional EP cardiologist and researcher, I have forged strong links with primary care. In 2012 I designed and developed the Primary Care Atrial Fibrillation (PCAF) service to improve stroke prevention, and this service has won several national awards for innovation and impact. For my work in reducing AF-related stroke burden in the community, I was awarded in 2014 the Arrhythmia Alliance Excellence in Practice Award for ‘Outstanding Individual who has contributed to Arrhythmia Services in the United Kingdom’. Awards and Honours June 2017: My research fellow (AH, with me as senior author) is to present one of the 10 Highest Ranking abstracts in the EHRA Cardiostim Europace sessions, Vienna October 2014: Arrhythmia Alliance Excellence in Practice Award for ‘Outstanding Individual who has contributed to Arrhythmia Services in the United Kingdom’ awarded at Heart Rhythm Congress, Birmingham Nov 2014: I have been invited to speak at the All Parliamentary Group on Atrial Fibrillation meeting at Westminster to share our experiences of engaging with primary care through the PCAF service October 2014: My research fellow (GW, with me as senior author) won the Young Investigator Award in the clinical category at the Heart Rhythm Congress, Birmingham Sep 2014: PCAF service won the Quality in Care winner of the ‘Anticoagulation Innovation of the Year Award’ at British Medical Association House, London June 2014: PCAF service was the winner of the ‘Innovation in Cardiac Pathways’ competition at the British Cardiac Society Sessions, Manchester June 2013: My research fellow (GW, with me as senior author) won the Highest Ranking abstract in the Heart Rhythm Category at the British Cardiac Society Sessions, London Previous Appointments Oct ‘04- Feb 07 Clinical Fellow in Electrophysiology St. Bartholomews Hospital, West Smithfield, London Oct ’03 –Sep ’04 Specialist Registrar in Cardiology St. Bartholomews Hospital, West Smithfield, London Jan ’03-Sep ’03 Specialist Registrar in Cardiology Royal London Hospital, Whitechapel, London 2 Dhiraj Gupta Mar 2017 Oct ’01- Dec ’02 Specialist Registrar in Cardiology London Chest Hospital, London Oct ’00-Sep ’01 Clinical fellow in cardiac electrophysiology St. George’s Hospital Medical School, London July ’97- Jun ’00 Registrar in cardiology and DM fellow All India Institute of Medical Sciences, New Delhi July ’94- Jun ’97 Senior House Officer, Internal Medicine & MD fellow Post Graduate Institute of Medical Education & Research, Chandigarh, India Academic Qualifications April 1994 MB BS (Bachelor of Medicine and Bachelor of Surgery) Moti Lal Nehru Medical College, Allahabad, India June 1997 MD (Doctor of Medicine) in Internal Medicine Post Graduate Institute of Medical Education & Research, Chandigarh, India June 2000 DM (Doctorate in Medicine) in Cardiology All India Institute of Medical Sciences, New Delhi, India July 2001 MRCP (UK) Royal College of Physicians, London October 2006 CCT (Cardiology) Joint Committee for Higher Medical Training (JCHMT), UK May 2012 FRCP (UK) Royal College of Physicians, London Research Supervision and PhD Examiner Roles Nov 2015-current: Liverpool University– Primary Supervisor MD (res) Dr A Hussein July 2013-Aug 2015: Imperial College, London – Primary Supervisor for MD (res) Dr M Das Jul 2011–Jun 2013: Imperial College, London –Primary Supervisor for MD (res) Dr G Wynn 2012-14: Early and Late Stage Review for Imperial College, London-PhD Dr S Panniker 2016-17: Early and Late Stage Review for Imperial College, London-PhD Dr I Mann 2016: External Examiner for PhD for City University, London- Dr Cory Tschabrunn 2015: External Examiner for PhD for Queen Mary University, London- Dr W Ullah 3 Dhiraj Gupta Mar 2017 Competitive Research Grants Obtained 2015 £255,520 from Investigator Initiated Studies Programme, Johnson and Johnson, CA, USA for ‘Pulmonary Vein Reconnection Following Ablation Index-Guided Ablation: a Success Evaluation (PRAISE)’, IIS-385: Chief Investigator, sole-applicant 2014 £1,240,000 from National Institute of Health Research (NIHR), Awarded for the twocentre ‘Catheter ablation or Surgical ablation for Atrial Fibrillation- the CASA-AF trial’: Principal Investigator, co-applicant with Dr Tom Wong 2014 £36,500 from Investigator Initiated Studies Programme, Johnson and Johnson, CA, USA for the international multicentre study ‘The value of Ablation index to predict sites of acute Pulmonary Vein Reconnection following ablation for Atrial Fibrillation’: Chief Investigator, sole-applicant 2013 £260,280 from Investigator Initiated Studies Programme, Johnson and Johnson, CA, USA for ‘pulmonary vein re-isolation as a routine strategy regardless of symptoms: the PRESSURE randomized controlled trial (IIS-239), as Chief Investigator, sole-applicant 2013 £50,000 from Sir Halley Stewart Trust: wages for an Arrhythmia Research Nurse, sole-applicant 2012-2016 £30,000 per year from Biosense Webster Educational Grant UKEG00328, for salary of Arrhythmia Clinical Fellow based at LHCH, sole-applicant Full Publications 1. M Das, GJ Wynn, Y Saeed, S Gomes, M Morgan, C Ronayne, LBonnett, JEP Waktare, DM Todd, MCS Hall, RL Snowdon, S Modi, D Gupta. Pulmonary Vein Isolation as a routine strategy regardless of symptoms: the PRESSURE randomised controlled trial. JACC Clin Electrophysiol (in press). DOI: 10.1016/j.jacep.2017.01.016 2. Chaturvedi V, Maille B, Gupta D. Bipolar Voltage Analysis with Multi-electrode Mapping. J Cardiovasc Electrophysiol 2017 (accepted for publication) 3. SS Poon, M Field, D Gupta, D Cameron. Surgical septal myectomy or alcohol septal ablation: which approach offers better outcomes for patients with hypertrophic obstructive cardiomyopathy? Interactive Cardiovascular and Thoracic Surgery 2017. DOI: 10.1093/icvts/ivx001 4. S Bartoletti, A Masoud, D Gupta. Left Atrial Appendage Occlusion With the Amulet Device Incomplete Occlusion, Thrombus Formation and the Importance of Intraprocedural Echocardiography JACC Clin Electrophysiol 2017:3:191 5. C Pearman, SS Poon, LJ Bonnett, S Haldar, T Wong, N Mediratta, D Gupta. Epicardial ablation alone vs. hybrid ablation for atrial fibrillation: A systematic review and meta-analysis. JACC Clin Electrophysiol (accepted for publication) 6. HR Khan, I K Hans, V Markides, D, Gupta, T Wong. Catheter Ablation Versus Thoracoscopic Surgical Ablation in Long Standing Persistent Atrial Fibrillation (CASA-AF): A Multicentre Randomised Clinical Trial Protocol. Trials 2017 (submitted for publication) 4 Dhiraj Gupta Mar 2017 7. A Hussein, M Das, V Chaturvedi, I K Asfour, N Daryanani, M Morgan, C Ronayne, M Shaw, R Snowdon, D Gupta. Prospective Use of Ablation Index Targets Improves Clinical Outcomes following Ablation for Atrial Fibrillation. J Cardiovasc Electrophysiol 2017(under review) 8. GJ Wynn, MEL Kadri, I Haq, M Das, S Modi , RL Snowdon, M Hall, JEP Waktare, DM Todd, D Gupta. Long term outcomes after ablation of persistent atrial fibrillation: an observational study over 6 years. Open Heart 2016; 3(2):e000394. doi: 10.1136/openhrt-2015-000394 9. SS Poon, RM Cooper, D Gupta. Endocardial radiofrequency septal ablation-a new option for non surgical septal reduction in patients with hypertrophic obstructive cardiomyopathy (HOCM): a systematic review of clinical studies. Int J Cardiol 2016; 222:772-774 10. S Bartoletti, S Parikh, D Gupta. Letter by Bartoletti et al regarding article, ‘Ablation of Persistent Atrial Fibrillation Targeting Low Voltage Areas with selective Activation Characteristics’. Circ Arrhythm Electrophysiol 2016; 9(7). Pii:e004302 11. M Das, JJ Loveday, GJ Wynn, S Gomes, Y Saeed, LBonnett, JEP Waktare, DM Todd, MCS Hall, RL Snowdon, S Modi, D Gupta. Ablation Index, a novel marker of ablation lesion quality: prediction of pulmonary vein reconnection at repeat electrophysiology study and regional differences in target values. Europace 2016 May 31. Pii:euw105 (Epub ahead of print) 12. W Ullah, A McLean, M Tayabjee, D Gupta, MR Ginks, GA Haywood, M O’Neill, PD Lambiase, MJ Earley, RJ Schilling. Randomised trial comparing pulmonary vein isolation using the SmartTouch catheter with or without real-time contact force data. Heart Rhythm 2016; 13(9):1761-7 13. M Das, GJ Wynn, M Morgan, B Lodge, JEP Waktare, DM Todd, MCS Hall, RL Snowdon, S Modi, D Gupta. Re-ablated sites of acute reconnection after pulmonary vein isolation do not predict sites of late reconnection at repeat electrophysiology study. J Cardiovasc Electrophysiol 2016;27: 381-9 14. M Das, L Panter, G Wynn, N Connor, J Mills, P Kirchhof, D Gupta. Primary Care Atrial Fibrillation (PCAF) Service: Outcomes from Consultant-led anticoagulation assessment clinics in the Primary Care setting. BMJ Open 2015;5:e009267 doi:10.1136/bmjopen-2015-009267 15. GJ Wynn, S Panniker, MCS Hall, RL Snowdon. JEP Waktare, V Markides, W Hussain, J Jarman, DM Todd, T Wong, D Gupta. Biatrial linear ablation in sustained non-permanent AF: Results of the Substrate Modification with Ablation and antiarrhythmic drugs in Non-Permanent Atrial Fibrillation Trial. Heart Rhythm 2016; 12(2):399-406 16. M Das, GJ Wynn, M Morgan, B Lodge, JEP Waktare, DM Todd, MCS Hall, RL Snowdon, S Modi, D Gupta. Recurrence of Atrial Tachyarrhythmia during the Second Month of the Blanking Period Predicts More Extensive Pulmonary Vein Reconnection at Repeat Electrophysiology Study. Circ Arrhythm Electrophysiol 2015: 8: 846-52 17. GJ Wynn, M Das, LJ Bonnett, MCS Hall, RL Snowdon. JEP Waktare, S Modi, DM Todd, D Gupta. A novel marker to predict early recurrence after atrial fibrillation ablation: The Ablation Effectiveness Quotient. J Cardiovasc Electrophysiol 2015; 26: 397-403 18. Cardiac Arrest in athletes and resuscitation. PB Bapat, A Bapat, D Gupta. J Intensive Care Soc 2015; 16: 85-86 5 Dhiraj Gupta Mar 2017 19. Relationship between Contact Force Sensing Technology and Medium Term Outcome of Atrial Fibrillation Ablation: A Multicenter Study of 600 Patients. Jarman JW, Panikker S, Das M, Wynn GJ, Ullah W, Kontogeorgis A, Haldar SK, Patel PJ, Hussain WJ, Markides V, Gupta D, Schilling RJ, Wong T. J Cardiovasc Electrophysiol 2015; 26: 378-84 20. Wynn GJ, Das M, Bonnett LJ, Gupta D. Quality-of-life benefits of catheter ablation of persistent atrial fibrillation: a reanalysis of data from the SARA study. Europace. 2015;17: 222-4 21. Wynn GJ, Das M, Bonnett LJ, Panikker S, Wong T, Gupta D. Efficacy of Catheter Ablation for Persistent Atrial Fibrillation: A Systematic Review and Meta-Analysis of Evidence from Randomised and Non-Randomised Controlled Trials. Circ Arrhythm Electrophysiol. 2014; 7: 841-52 22. GJ Wynn, I Haq, J Hung, LJ Bonnett, G Lewis, M Webber, JEP Waktare, S Modi, RL Snowdon, MCS Hall, DM Todd, D Gupta. Improving safety in catheter ablation for atrial fibrillation: a prospective study of the use of ultrasound to guide vascular access. J Cardiovasc Electrophysiol. 2014; 25(7): 680-5 23. GJ Wynn, DM Todd, M Webber, LJ Bonnett, J McShane, P Kirchhof, D Gupta. The European Heart Rhythm Association Symptom Classification for Atrial Fibrillation: Validation and Improvement through a Simple Modification. Europace 2014;16(7):965-72 24. Wynn GJ, Das M, Gupta D. Re: Caution over use of catheter ablation for atrial fibrillation. BMJ 2013. http://www.bmj.com/content/347/bmj.f5277/rr/662301 25. Haldar S, Jarman JWE, Panikker S, Jones DG, Salukhe T, Gupta D, Wynn G, Hussain W, Markides V, Wong T. Contact force sensing technology identifies sites of inadequate contact and reduces acute pulmonary vein reconnection: A prospective case control study. Int J Cardiol 2013;168: 1160-6 26. R Liew, V Baker, L Richmond, K Rajappan, D Gupta, M Finlay, G Thomas, S Harris, M Earley, S Sporton, R Schilling. A randomised controlled trial of conventional catheter ablation with a novel minimal catheter approach for regular supraventricular tachycardia. Europace 2009; 11(8):1057-64 27. Showkathali R, Earley MJ, Gupta D, Alzetani M, Harris S, Kistler PM, Sporton SC, Schilling RJ. Current case mix and results of catheter ablation of regular supraventricular tachycardia: are we giving unrealistic expectations to patients? Europace 2007;9(11):1064-1068 28. Liew R, Rajappan K, Gupta D, Kistler P, Schilling R. Percutaneous epicardial ablation reverses ventricular tachycardia mediated cardiomyopathy. J Interv Card Electrophysiol. 2007;18(3):265-7 29. D Gupta, RK Al-Lamee, MJ Earley, PM Kistler, SJ Harris, AW Nathan, SC Sporton, RJ Schilling. Cryoablation compared with radiofrequency ablation for atrioventricular nodal reentrant tachycardia: analysis of factors contributing to acute and follow up outcome. Europace. 2006;8(12):1022-6 30. D Gupta, MJ Earley, GA Haywood, L Richmond, M Haywood, P Kojodjojo, SC Sporton, NS Peters, P Broadhurst, RJ Schilling Can atrial fibrillation with a coarse electrocardiographic appearance be treated with catheter ablation of the tricuspid valve-inferior vena cava isthmus? Heart. 2007;93(6):688-93 31. PM Kistler, K Rajappan, D Gupta, M Jahangir, MJ Earley, S Harris, D Abrams, R Liew, S Ellis, SC Sporton. RJ Schilling. The impact of CT integration into an electroanatomic mapping system on clinical outcomes of atrial fibrillation. J Cardiovasc Electrophysiol. 2006;17(10):1093-101 6 Dhiraj Gupta Mar 2017 32. MJ Earley, R Showkathali, M Alzetani, PM Kistler, D Gupta, DJ Abrams, JA Horrocks , SJ Harris, SC Sporton, RJ Schilling. Radiofrequency ablation of arrhythmias guided by non-fluoroscopic catheter location: a prospective randomized trial. Eur Heart J. 2006;27(10):1223-9. 33. S Vallapuri, D Gupta, KK Talwar, M Billie, MC Mehta, AP Morise, A Jain. Comparison of atherosclerotic risk factors in Asian Indian and American caucasian patients with angiographic coronary artery disease. Am J Cardiol 2002; 90: 11471150 34. D Gupta, A Saxena, SS Kothari, R Juneja. Factors influencing late course of residual valvular and infundibular gradients following pulmonary valve balloon dilatation. Int J Cardiol 2001; 79 (2-3): 143-9. 35. D Gupta, A Saxena, SS Kothari, R Juneja, M Rajani, S Sharma, P Venugopal. Detection of coronary anomalies in Tetralogy of Fallot using a specific angiographic protocol. Am J Cardiol 2001; 87: 241-44. 36. D Gupta, Kothari SS, Bahl VK, Goswami KC, Talwar KK, Manchanda SC, Venugopal P. Thrombolytic therapy for prosthetic valve thrombosis: short and long term results. Am Heart J 2000; 140 (6): 906-16. 37. D Gupta, Chawla YK, Dhiman RK, Suri S, Dilawari JB. Clinical significance of patent paraumbilical vein in patients with liver cirrhosis. Digestive Diseases and Sciences 2000; 45(9): 1861-4. CONFERENCE PAPERS (PAST 24 MONTHS ONLY) PRESENTATIONS AT LATE BREAKING CLINICAL TRIALS SESSIONS: 1. B Schmidt, J Lund, J Sinisalo, C Piorkowski, D Gupta, V Paul, C Tondo, P Della Bella. The Influence of post-implant antithrombotic drug therapy on the incidence of device thrombus and stroke in the AMULET-Registry Study. Late Breaking Clinical Trials. Heart Rhythm Sessions, Chicago, USA May 2017. 2. D Gupta, GJ Wynn, Y Saeed, S Gomes, M Morgan, C Ronayne, LBonnett, JEP Waktare, DM Todd, MCS Hall, RL Snowdon, S Modi, M Das. Pulmonary Vein Isolation as a routine strategy regardless of symptoms: the PRESSURE randomised controlled trial. Late Breaking Clinical Trials. Heart Rhythm Sessions, San Francisco, USA May 2016. 3. W Ullah, A McLean, M Tayabjee, D Gupta, MR Ginks, GA Haywood, M O’Neill, PD Lambiase, MJ Earley, RJ Schilling. Randomised trial comparing pulmonary vein isolation using the SmartTouch catheter with or without real-time contact force data. Late Breaking Clinical Trials. Heart Rhythm Sessions, San Francisco, USA May 2016. 4. GJ Wynn, S Panikker, M Morgan, M Hall, J Waktare, V Markides, W Hussain, TV Salukhe, S Modi, JWE. Jarman, DG. Jones, RL Snowdon, D Todd, T Wong, D Gupta. Effect of linear ablation in substrate-based AF: Results of the Substrate Modification with Ablation and antiarrhythmic drugs in Non-Permanent Atrial Fibrillation Trial. Late Breaking Clinical Trials. Heart Rhythm Sessions, Boston, USA May 2015 ORAL PRESENTATIONS: 5. A. Hussein, M. Das, I. Asfour, M. Morgan, C. Ronayne, M. Shaw, R. Snowdon, D. Gupta. Prospective Use of Ablation Index Targets Improves Clinical Outcomes following Ablation for Atrial Fibrillation. EHRA Europace Sessions, Vienna June 2017 6. A. Hussein, M. Das, I. Asfour, M. Morgan, C. Ronayne, M. Shaw, R. Snowdon, D. Gupta. Ablation Index-Guided Pulmonary Vein Isolation For Atrial Fibrillation May 7 Dhiraj Gupta Mar 2017 Improve Clinical outcomes In Comparison To Contact Force-Guided Ablation. Heart Rhythm Congress, Birmingham, Oct 2016. Europace 2016; 18(1 Suppl 2): 33 7. CM Pearman, D Todd, R King, M Hall, S Modi, N Mediratta, D Gupta. The Procedural Complication Rates And Short-Term Success Rates Of Thoracoscopic AF Ablation During The Institutional Learning Curve. Heart Rhythm Congress, Birmingham, Oct 2016. Europace 2016;18(1 Suppl 2): 34 POSTER PRESENTATIONS: 8. B Maille, A Hussein, V Chaturvedi, M Morgan, C Ronayne, R Snowdon, D Gupta. Reverse Remodelling of the Left Atrium occurs early after Catheter ablation for Persistent Atrial Fibrillation. EHRA Europace Sessions, Vienna June 2017 9. Hussein A, Das M, Wynn GJ, Morgan M, Waktare JEP, Todd DM, Hall MCS, Snowdon RL, Modi S, Gupta D.The Relationship Between The Effective Refractory Period Of Reconnected Pulmonary Veins At Repeat Electrophysiology Study And Recurrence Of Atrial Tachycarrhythmia Beyond One Month After Pulmonary Vein Isolation. Heart Rhythm Congress, Birmingham, Oct 2016. Europace 2016;18(1 Suppl 2): 50 10. CM Pearman, J Parry, L Garth, J Chapman, D Todd, J Hobbs, S Modi, J Waktare, M Hall, D Gupta, R Snowdon. Patients Undergoing SVT Ablation Have A High Incidence Of Secondary Arrhythmia On Follow Up: Implications For Pre-Procedure Counselling. Heart Rhythm Congress, Birmingham, Oct 2016. Europace 2016;18(1 Suppl 2): 122 11. Y Saeed, A Hussein, WV Ding, L McLenghan, M Meah, Wynn GJ, Waktare JEP, Todd DM, Hall MCS, Snowdon RL, Modi S, Gupta D. The Impact of Simple Protocol Changes in Improving Safety of Catheter Ablation for Atrial Fibrillation: Experience from a Tertiary Centre in England. EHRA Europace Sessions, Nice June 2016 Europace 2016; 18(1 Suppl 1) 75 12. S Bartoletti, P Velavan, J Barclay, A Khalatbari, N Sharma, L Morrison, T Fairbairn, D Gupta. Left Atrial Appendage Occlusion for Stroke Prevention in Atrial Fibrillation: Contemporary Commissioning Through Evaluation Experience from the United Kingdom. EHRA Europace Sessions, Nice June 2016. Europace 2016;18(1 Suppl 1) 86 13. Y Saeed, A Hussein, WV Ding, L McLenghan, M Meah, Wynn GJ, Waktare JEP, Todd DM, Hall MCS, Snowdon RL, Modi S, Gupta D. Improving Safety and Clinical Outcomes for Atrial Fibrillation Ablation: Should Our Threshold for Referral and for Intervention Become Lower? British Cardiac Society sessions, Manchester, June 2016 Heart 102(Suppl 6):A46-A46 14. S Bartoletti, P Velavan, J Barclay, A Khalatbari, N Sharma, L Morrison, T Fairbairn, D Gupta. Left Atrial Appendage Occlusion for Stroke Prevention in Atrial Fibrillation: Contemporary Experience from a Commissioning Through Evaluation Site. British Cardiac Society sessions, Manchester, June 2016. Heart 102(Suppl 6):A45-A46 15. Das M, Wynn GJ, Morgan M, Lodge B, Waktare JEP, Todd DM, Hall MCS, Snowdon RL, Modi S, Gupta D. Re-ablated sites of acute reconnection after pulmonary vein isolation do not predict sites of late reconnection at repeat electrophysiology study. Heart Rhythm Sessions, San Francisco, USA May 2016. Heart Rhythm 2015, 12(5S):S121. 16. Das M, Wynn GJ, Morgan M, Lodge B, Waktare JEP, Todd DM, Hall MCS, Snowdon RL, Modi S, Gupta D. Ablation Index predicts sites of reconnection at repeat electrophysiology study following pulmonary vein isolation. Heart Rhythm Sessions, San Francisco, USA May 2016. Heart Rhythm 2015, 12(5S):S362. 17. M Das, M Duytschaever, D Gupta, P Lukac, J Sorrel, T Phlips, AS Jadidi, H Nakagawa Ablation Index Predicts Sites of Acute Reconnection after Pulmonary Vein Isolation (PVI): a Multi-Center Retrospective Analysis. Heart Rhythm Sessions, San Francisco, USA May 2016. Heart Rhythm 2015, 12(5S):S86 18. Das M, Piddock N, Wynn GJ, Morgan M, Lodge B, Waktare JEP, Todd DM, Hall MCS, Snowdon RL, Modi S, Gupta D. Low impedance drop predicts sites of acute reconnection following pulmonary vein isolation. Heart Rhythm Sessions, San Francisco, 8 Dhiraj Gupta Mar 2017 USA May 2016. Heart Rhythm 2015, 12(5S):S445 Current Research Projects 1. VISTAX study (Clinicaltrials.gov: NCT03062046): International Multicenter Study at 15 European hospitals. Chief Investigator 2. Pulmonary vein Reconnection following Ablation Index-guided ablation: a Success Evaluation (PRAISE) (Clinicaltrials.gov: NCT02628730): International multi-centre trial. Chief Investigator 3. Catheter ablation vs Surgical Ablation for AF (CASA-AF) (Clinicaltrials.gov: NCT02755688): NIHR funded 3 centre trial with Royal Brompton and Harefield Hospitals, London. Principal Investigator 4. Amplatzer Amulet LAA Occluder trial. (Clinicaltrials.gov: NCT02879448). International multicenter trial. Principal Investigator Educational Activities (past 24 months only) Reviewer for Scientific Journals: I am a manuscript reviewer for the following journals o Heart (Impact Factor, 2016: 5.6) o Europace (Impact Factor, 2016: 5.9) o Journal of the American College of Cardiology: Arrhythmia and Electrophysiology Member of Scientific committee, Heart Rhythm Congress from 2014 to date Head of AFA sessions, and assessor for abstracts at Heart Rhythm Congress: 2014 till date I have conceived, organised and chaired the first two annual editions of the ‘North West AF and Stroke Symposium’ in Liverpool in May 2016 and April 2017. Invited Talks at National and International Scientific Conferences (past 24 months only) 1. European Heart Rhythm Association Europace-Cardiostim, Vienna 18-21 June 2017: ‘Debate: Cryoablation should be first choice in persistent atrial fibrillation – Contra’. 2. European Heart Rhythm Association Europace-Cardiostim, Vienna 18-21 June 2017: ‘The Impact of Contact Force on Procedural Outcome’. 3. 16th Atrial Fibrillation symposium, Hague, Netherlands, 23-24 March 2017: ‘Randomised trials of Contact Force efficacy: a critical look at the literature’. 4. 7th Global Left Atrial Appendage Occlusion Summit, Copenhagen, 3 Feb 2017: ‘Vascular complications: how to best avoid?’ 5. A year in Cardiology: a British Cardiac Society Symposium, Royal College of Physicians, London, 16 Dec 2016: ‘Electrophysiology: what did 2016 bring?’ 6. Heart Rhythm Congress, Birmingham, UK 10-12 Oct 2016: ‘How do you keep ablations on track’ 7. Heart Rhythm Congress, Birmingham, UK 11 Oct 2016: ‘LAA Occlusion in the UK: what has 2 years of Commissioning through Evaluation taught us?’ 8. New Swiss Horizons Meeting, Lenzerheide, Switzerland. 24 Sep 2016: ‘Use of Ablation Index targets in AF ablation’. 9. Late Breaking Clinical Trials, Heart Rhythm Society Sessions, San Francisco May 2016: ‘Pulmonary vein re-isolation as a routine strategy- a success rate evaluation: The PRESSURE trial’ 10. 15th Atrial Fibrillation symposium, Rome 17-18 Mar 2016: ‘Extracardiac neural injury with AF ablation.’ 11. 13th Biannual Dead sea EP symposium, Tel-Aviv 7-9 Mar 2016: ‘Debate: Only PV Isolation is Needed for Persistent AF: PRO’ 9 Dhiraj Gupta Mar 2017 12. 13th Biannual Dead sea EP symposium, Tel-Aviv 7-9 Mar 2016: ‘The Utility and High Reproducibility of a Novel Ablation Strategy’ 13. 14th Biannual edition of the Venice Arrhythmias, Venice, Italy 16-18 Oct 2015: ‘Mapping and ablation in Atrial Fibrillation: how can we evaluate lesion formation?’ 14. Heart Rhythm Congress, Birmingham, UK 6-8 Oct 2015: ‘How to choose your ablation tool for PVI? Are considerations of procedural efficacy and lab work-flow at cross-purposes?’ 15. Heart Rhythm Congress, Birmingham, UK 6-8 Oct 2015: ‘Left atrial appendage Occlusion: where does it sit amongst other preventive measures of stroke?’ 16. Heart Failure and Co-morbidities: Symposium at the Royal College of General Practitioners, 24 June 2016: ‘Implementing effective AF treatment and anticoagulation in the NHS in 2016’ 17. Annual Conference of the British Association of Cardiac Prevention and Rehabilitation, 2 Oct 2015: ‘New Horizons in AF management’ 10