Download Dr Dhiraj Gupta

Dr Dhiraj Gupta
MBBS, MD, DM, FRCP (UK)
Date of Birth
08 October 1970
Sex
Male
Nationality
British
Telephone
01516001793 (Office)
Email
[email protected]
GMC
5205561 (Full Registration)
Current Appointments
March 2007 till date
Consultant Cardiologist / Electrophysiologist
The Liverpool Heart and Chest Hospital
July 2011 till date
Honorary Senior Lecturer, Imperial College, London
June 2012 till date
Clinical Lead and Co-founder, Primary Care AF service
Nov 2014 till date
Medical Advisor, Atrial Fibrillation Association UK
Aug 2015 till date
Head, Arrhythmia Working Group, ICMS
Oct 2015 till date
Member of Council, British Heart Rhythm Society
Nov 2015 till date
Honorary Senior Lecturer, University of Liverpool
Oct 2014 till date
Member, Scientific Committee, Heart Rhythm Congress
Brief Profile
I am a consultant cardiologist/ electrophysiologist at the Liverpool Heart and Chest Hospital
(LHCH) since 2007. LHCH provides a regional electrophysiology (EP) service to a
population of 2.8 million, and is one of the largest cardiac centres in the United Kingdom. I
am a very high volume operator in interventional EP, and have performed over 200 ablation
cases annually since 2009. I am the trust lead for Left Atrial Appendage Occluder (LAAO)
Service, and our hospital was one of 10 sites selected nationally for this service by the NHS
England as part of the Commissioning through Evaluation (CtE) program. I proctor
cardiologists nationally and internationally for LAAO implants, and I have been awarded
NHS Clinical Excellence Awards in 2010, 2014 and 2015.
I have held the position of Honorary Senior Lecturer at Imperial College London since 2011,
and head the arrhythmia working group of the Institute of Cardiovascular Medicine and
Science, a research collaboration between Royal Brompton Hospital and LHCH. I am the
primary supervisor for three MD (res) students at Imperial, and also assess the progress of
other Students at Imperial College working towards higher research degrees. I have examined
PhD candidates for Queen Mary University, and City University, London. I am the Chief
Investigator for four ablation trials (PRESSURE, SMANPAF, PRAISE, and VISTAX), and
Dhiraj Gupta
Mar 2017
have been successful in obtaining over £1.5 million in competitive research grants. In the past
3 years, I have authored over 15 scientific publications as senior author.
I have earned repute for my expertise in treating patients suffering from Atrial Fibrillation
(AF), and I work closely with the British Heart Foundation to provide education and training
to their staff nationally. I am also member of the Medical Advisory Committee of the national
charity, AF Association. I have been elected to the Council of British Heart Rhythm Society
in Oct 2015 for a term of three years, and as a council member I help shape national
guidelines and policies related to arrhythmia care.
In addition to my roles as an interventional EP cardiologist and researcher, I have forged
strong links with primary care. In 2012 I designed and developed the Primary Care Atrial
Fibrillation (PCAF) service to improve stroke prevention, and this service has won several
national awards for innovation and impact. For my work in reducing AF-related stroke burden
in the community, I was awarded in 2014 the Arrhythmia Alliance Excellence in Practice
Award for ‘Outstanding Individual who has contributed to Arrhythmia Services in the United
Kingdom’.
Awards and Honours
June 2017: My research fellow (AH, with me as senior author) is to present one of the 10
Highest Ranking abstracts in the EHRA Cardiostim Europace sessions, Vienna
October 2014: Arrhythmia Alliance Excellence in Practice Award for ‘Outstanding
Individual who has contributed to Arrhythmia Services in the United Kingdom’ awarded at
Heart Rhythm Congress, Birmingham
Nov 2014: I have been invited to speak at the All Parliamentary Group on Atrial Fibrillation
meeting at Westminster to share our experiences of engaging with primary care through the
PCAF service
October 2014: My research fellow (GW, with me as senior author) won the Young
Investigator Award in the clinical category at the Heart Rhythm Congress, Birmingham
Sep 2014: PCAF service won the Quality in Care winner of the ‘Anticoagulation Innovation
of the Year Award’ at British Medical Association House, London
June 2014: PCAF service was the winner of the ‘Innovation in Cardiac Pathways’
competition at the British Cardiac Society Sessions, Manchester
June 2013: My research fellow (GW, with me as senior author) won the Highest Ranking
abstract in the Heart Rhythm Category at the British Cardiac Society Sessions, London
Previous Appointments
Oct ‘04- Feb 07
Clinical Fellow in Electrophysiology
St. Bartholomews Hospital, West Smithfield, London
Oct ’03 –Sep ’04
Specialist Registrar in Cardiology
St. Bartholomews Hospital, West Smithfield, London
Jan ’03-Sep ’03
Specialist Registrar in Cardiology
Royal London Hospital, Whitechapel, London
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Mar 2017
Oct ’01- Dec ’02
Specialist Registrar in Cardiology
London Chest Hospital, London
Oct ’00-Sep ’01
Clinical fellow in cardiac electrophysiology
St. George’s Hospital Medical School, London
July ’97- Jun ’00
Registrar in cardiology and DM fellow
All India Institute of Medical Sciences, New Delhi
July ’94- Jun ’97
Senior House Officer, Internal Medicine & MD fellow
Post Graduate Institute of Medical Education &
Research, Chandigarh, India
Academic Qualifications
April 1994
MB BS (Bachelor of Medicine and Bachelor of Surgery)
Moti Lal Nehru Medical College, Allahabad, India
June 1997
MD (Doctor of Medicine) in Internal Medicine
Post Graduate Institute of Medical Education & Research, Chandigarh,
India
June 2000
DM (Doctorate in Medicine) in Cardiology
All India Institute of Medical Sciences, New Delhi, India
July 2001
MRCP (UK) Royal College of Physicians, London
October 2006
CCT (Cardiology)
Joint Committee for Higher Medical Training (JCHMT), UK
May 2012
FRCP (UK) Royal College of Physicians, London
Research Supervision and PhD Examiner Roles
Nov 2015-current: Liverpool University– Primary Supervisor MD (res) Dr A Hussein
July 2013-Aug 2015: Imperial College, London – Primary Supervisor for MD (res) Dr M Das
Jul 2011–Jun 2013: Imperial College, London –Primary Supervisor for MD (res) Dr G Wynn
2012-14: Early and Late Stage Review for Imperial College, London-PhD Dr S Panniker
2016-17: Early and Late Stage Review for Imperial College, London-PhD Dr I Mann
2016: External Examiner for PhD for City University, London- Dr Cory Tschabrunn
2015: External Examiner for PhD for Queen Mary University, London- Dr W Ullah
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Competitive Research Grants Obtained
2015 £255,520 from Investigator Initiated Studies Programme, Johnson and Johnson, CA,
USA for ‘Pulmonary Vein Reconnection Following Ablation Index-Guided Ablation: a
Success Evaluation (PRAISE)’, IIS-385: Chief Investigator, sole-applicant
2014 £1,240,000 from National Institute of Health Research (NIHR), Awarded for the twocentre ‘Catheter ablation or Surgical ablation for Atrial Fibrillation- the CASA-AF trial’:
Principal Investigator, co-applicant with Dr Tom Wong
2014 £36,500 from Investigator Initiated Studies Programme, Johnson and Johnson, CA,
USA for the international multicentre study ‘The value of Ablation index to predict sites of
acute Pulmonary Vein Reconnection following ablation for Atrial Fibrillation’: Chief
Investigator, sole-applicant
2013 £260,280 from Investigator Initiated Studies Programme, Johnson and Johnson, CA,
USA for ‘pulmonary vein re-isolation as a routine strategy regardless of symptoms: the
PRESSURE randomized controlled trial (IIS-239), as Chief Investigator, sole-applicant
2013 £50,000 from Sir Halley Stewart Trust: wages for an Arrhythmia Research Nurse,
sole-applicant
2012-2016 £30,000 per year from Biosense Webster Educational Grant UKEG00328, for
salary of Arrhythmia Clinical Fellow based at LHCH, sole-applicant
Full Publications
1. M Das, GJ Wynn, Y Saeed, S Gomes, M Morgan, C Ronayne, LBonnett, JEP
Waktare, DM Todd, MCS Hall, RL Snowdon, S Modi, D Gupta. Pulmonary Vein
Isolation as a routine strategy regardless of symptoms: the PRESSURE randomised
controlled trial. JACC Clin Electrophysiol (in press). DOI:
10.1016/j.jacep.2017.01.016
2. Chaturvedi V, Maille B, Gupta D. Bipolar Voltage Analysis with Multi-electrode
Mapping. J Cardiovasc Electrophysiol 2017 (accepted for publication)
3. SS Poon, M Field, D Gupta, D Cameron. Surgical septal myectomy or alcohol septal
ablation: which approach offers better outcomes for patients with hypertrophic
obstructive cardiomyopathy? Interactive Cardiovascular and Thoracic Surgery 2017.
DOI: 10.1093/icvts/ivx001
4. S Bartoletti, A Masoud, D Gupta. Left Atrial Appendage Occlusion With the Amulet
Device Incomplete Occlusion, Thrombus Formation and the Importance of
Intraprocedural Echocardiography JACC Clin Electrophysiol 2017:3:191
5. C Pearman, SS Poon, LJ Bonnett, S Haldar, T Wong, N Mediratta, D Gupta.
Epicardial ablation alone vs. hybrid ablation for atrial fibrillation: A systematic
review and meta-analysis. JACC Clin Electrophysiol (accepted for publication)
6. HR Khan, I K Hans, V Markides, D, Gupta, T Wong. Catheter Ablation Versus
Thoracoscopic Surgical Ablation in Long Standing Persistent Atrial Fibrillation
(CASA-AF): A Multicentre Randomised Clinical Trial Protocol. Trials 2017
(submitted for publication)
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7. A Hussein, M Das, V Chaturvedi, I K Asfour, N Daryanani, M Morgan, C Ronayne,
M Shaw, R Snowdon, D Gupta. Prospective Use of Ablation Index Targets Improves
Clinical Outcomes following Ablation for Atrial Fibrillation. J Cardiovasc
Electrophysiol 2017(under review)
8. GJ Wynn, MEL Kadri, I Haq, M Das, S Modi , RL Snowdon, M Hall, JEP Waktare,
DM Todd, D Gupta. Long term outcomes after ablation of persistent atrial
fibrillation: an observational study over 6 years. Open Heart 2016; 3(2):e000394. doi:
10.1136/openhrt-2015-000394
9. SS Poon, RM Cooper, D Gupta. Endocardial radiofrequency septal ablation-a new
option for non surgical septal reduction in patients with hypertrophic obstructive
cardiomyopathy (HOCM): a systematic review of clinical studies. Int J Cardiol 2016;
222:772-774
10. S Bartoletti, S Parikh, D Gupta. Letter by Bartoletti et al regarding article, ‘Ablation
of Persistent Atrial Fibrillation Targeting Low Voltage Areas with selective
Activation Characteristics’. Circ Arrhythm Electrophysiol 2016; 9(7). Pii:e004302
11. M Das, JJ Loveday, GJ Wynn, S Gomes, Y Saeed, LBonnett, JEP Waktare, DM Todd,
MCS Hall, RL Snowdon, S Modi, D Gupta. Ablation Index, a novel marker of
ablation lesion quality: prediction of pulmonary vein reconnection at repeat
electrophysiology study and regional differences in target values. Europace 2016 May
31. Pii:euw105 (Epub ahead of print)
12. W Ullah, A McLean, M Tayabjee, D Gupta, MR Ginks, GA Haywood, M O’Neill,
PD Lambiase, MJ Earley, RJ Schilling. Randomised trial comparing pulmonary vein
isolation using the SmartTouch catheter with or without real-time contact force data.
Heart Rhythm 2016; 13(9):1761-7
13. M Das, GJ Wynn, M Morgan, B Lodge, JEP Waktare, DM Todd, MCS Hall, RL
Snowdon, S Modi, D Gupta. Re-ablated sites of acute reconnection after pulmonary
vein isolation do not predict sites of late reconnection at repeat electrophysiology
study. J Cardiovasc Electrophysiol 2016;27: 381-9
14. M Das, L Panter, G Wynn, N Connor, J Mills, P Kirchhof, D Gupta. Primary Care
Atrial Fibrillation (PCAF) Service: Outcomes from Consultant-led anticoagulation
assessment clinics in the Primary Care setting. BMJ Open 2015;5:e009267
doi:10.1136/bmjopen-2015-009267
15. GJ Wynn, S Panniker, MCS Hall, RL Snowdon. JEP Waktare, V Markides, W
Hussain, J Jarman, DM Todd, T Wong, D Gupta. Biatrial linear ablation in sustained
non-permanent AF: Results of the Substrate Modification with Ablation and
antiarrhythmic drugs in Non-Permanent Atrial Fibrillation Trial. Heart Rhythm 2016;
12(2):399-406
16. M Das, GJ Wynn, M Morgan, B Lodge, JEP Waktare, DM Todd, MCS Hall, RL
Snowdon, S Modi, D Gupta. Recurrence of Atrial Tachyarrhythmia during the
Second Month of the Blanking Period Predicts More Extensive Pulmonary Vein
Reconnection at Repeat Electrophysiology Study. Circ Arrhythm Electrophysiol 2015:
8: 846-52
17. GJ Wynn, M Das, LJ Bonnett, MCS Hall, RL Snowdon. JEP Waktare, S Modi, DM
Todd, D Gupta. A novel marker to predict early recurrence after atrial fibrillation
ablation: The Ablation Effectiveness Quotient. J Cardiovasc Electrophysiol 2015; 26:
397-403
18. Cardiac Arrest in athletes and resuscitation. PB Bapat, A Bapat, D Gupta. J Intensive
Care Soc 2015; 16: 85-86
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19. Relationship between Contact Force Sensing Technology and Medium Term
Outcome of Atrial Fibrillation Ablation: A Multicenter Study of 600 Patients. Jarman
JW, Panikker S, Das M, Wynn GJ, Ullah W, Kontogeorgis A, Haldar SK, Patel PJ,
Hussain WJ, Markides V, Gupta D, Schilling RJ, Wong T. J Cardiovasc
Electrophysiol 2015; 26: 378-84
20. Wynn GJ, Das M, Bonnett LJ, Gupta D. Quality-of-life benefits of catheter ablation
of persistent atrial fibrillation: a reanalysis of data from the SARA study. Europace.
2015;17: 222-4
21. Wynn GJ, Das M, Bonnett LJ, Panikker S, Wong T, Gupta D. Efficacy of Catheter
Ablation for Persistent Atrial Fibrillation: A Systematic Review and Meta-Analysis
of Evidence from Randomised and Non-Randomised Controlled Trials. Circ
Arrhythm Electrophysiol. 2014; 7: 841-52
22. GJ Wynn, I Haq, J Hung, LJ Bonnett, G Lewis, M Webber, JEP Waktare, S Modi,
RL Snowdon, MCS Hall, DM Todd, D Gupta. Improving safety in catheter ablation
for atrial fibrillation: a prospective study of the use of ultrasound to guide vascular
access. J Cardiovasc Electrophysiol. 2014; 25(7): 680-5
23. GJ Wynn, DM Todd, M Webber, LJ Bonnett, J McShane, P Kirchhof, D Gupta. The
European Heart Rhythm Association Symptom Classification for Atrial Fibrillation:
Validation and Improvement through a Simple Modification. Europace
2014;16(7):965-72
24. Wynn GJ, Das M, Gupta D. Re: Caution over use of catheter ablation for atrial
fibrillation. BMJ 2013. http://www.bmj.com/content/347/bmj.f5277/rr/662301
25. Haldar S, Jarman JWE, Panikker S, Jones DG, Salukhe T, Gupta D, Wynn G,
Hussain W, Markides V, Wong T. Contact force sensing technology identifies sites of
inadequate contact and reduces acute pulmonary vein reconnection: A prospective
case control study. Int J Cardiol 2013;168: 1160-6
26. R Liew, V Baker, L Richmond, K Rajappan, D Gupta, M Finlay, G Thomas, S
Harris, M Earley, S Sporton, R Schilling. A randomised controlled trial of
conventional catheter ablation with a novel minimal catheter approach for regular
supraventricular tachycardia. Europace 2009; 11(8):1057-64
27. Showkathali R, Earley MJ, Gupta D, Alzetani M, Harris S, Kistler PM, Sporton SC,
Schilling RJ. Current case mix and results of catheter ablation of regular
supraventricular tachycardia: are we giving unrealistic expectations to patients?
Europace 2007;9(11):1064-1068
28. Liew R, Rajappan K, Gupta D, Kistler P, Schilling R. Percutaneous epicardial
ablation reverses ventricular tachycardia mediated cardiomyopathy. J Interv Card
Electrophysiol. 2007;18(3):265-7
29. D Gupta, RK Al-Lamee, MJ Earley, PM Kistler, SJ Harris, AW Nathan, SC Sporton,
RJ Schilling. Cryoablation compared with radiofrequency ablation for atrioventricular
nodal reentrant tachycardia: analysis of factors contributing to acute and follow up
outcome. Europace. 2006;8(12):1022-6
30. D Gupta, MJ Earley, GA Haywood, L Richmond, M Haywood, P Kojodjojo, SC
Sporton, NS Peters, P Broadhurst, RJ Schilling Can atrial fibrillation with a coarse
electrocardiographic appearance be treated with catheter ablation of the tricuspid
valve-inferior vena cava isthmus? Heart. 2007;93(6):688-93
31. PM Kistler, K Rajappan, D Gupta, M Jahangir, MJ Earley, S Harris, D Abrams, R
Liew, S Ellis, SC Sporton. RJ Schilling. The impact of CT integration into an
electroanatomic mapping system on clinical outcomes of atrial fibrillation. J
Cardiovasc Electrophysiol. 2006;17(10):1093-101
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32. MJ Earley, R Showkathali, M Alzetani, PM Kistler, D Gupta, DJ Abrams, JA
Horrocks , SJ Harris, SC Sporton, RJ Schilling. Radiofrequency ablation of
arrhythmias guided by non-fluoroscopic catheter location: a prospective randomized
trial. Eur Heart J. 2006;27(10):1223-9.
33. S Vallapuri, D Gupta, KK Talwar, M Billie, MC Mehta, AP Morise, A Jain.
Comparison of atherosclerotic risk factors in Asian Indian and American caucasian
patients with angiographic coronary artery disease. Am J Cardiol 2002; 90: 11471150
34. D Gupta, A Saxena, SS Kothari, R Juneja. Factors influencing late course of residual
valvular and infundibular gradients following pulmonary valve balloon dilatation. Int
J Cardiol 2001; 79 (2-3): 143-9.
35. D Gupta, A Saxena, SS Kothari, R Juneja, M Rajani, S Sharma, P Venugopal.
Detection of coronary anomalies in Tetralogy of Fallot using a specific angiographic
protocol. Am J Cardiol 2001; 87: 241-44.
36. D Gupta, Kothari SS, Bahl VK, Goswami KC, Talwar KK, Manchanda SC,
Venugopal P. Thrombolytic therapy for prosthetic valve thrombosis: short and long
term results. Am Heart J 2000; 140 (6): 906-16.
37. D Gupta, Chawla YK, Dhiman RK, Suri S, Dilawari JB. Clinical significance of
patent paraumbilical vein in patients with liver cirrhosis. Digestive Diseases and
Sciences 2000; 45(9): 1861-4.
CONFERENCE PAPERS (PAST 24 MONTHS ONLY)
PRESENTATIONS AT LATE BREAKING CLINICAL TRIALS SESSIONS:
1. B Schmidt, J Lund, J Sinisalo, C Piorkowski, D Gupta, V Paul, C Tondo, P Della Bella.
The Influence of post-implant antithrombotic drug therapy on the incidence of device
thrombus and stroke in the AMULET-Registry Study. Late Breaking Clinical Trials.
Heart Rhythm Sessions, Chicago, USA May 2017.
2. D Gupta, GJ Wynn, Y Saeed, S Gomes, M Morgan, C Ronayne, LBonnett, JEP Waktare,
DM Todd, MCS Hall, RL Snowdon, S Modi, M Das. Pulmonary Vein Isolation as a
routine strategy regardless of symptoms: the PRESSURE randomised controlled trial.
Late Breaking Clinical Trials. Heart Rhythm Sessions, San Francisco, USA May 2016.
3. W Ullah, A McLean, M Tayabjee, D Gupta, MR Ginks, GA Haywood, M O’Neill, PD
Lambiase, MJ Earley, RJ Schilling. Randomised trial comparing pulmonary vein isolation
using the SmartTouch catheter with or without real-time contact force data. Late Breaking
Clinical Trials. Heart Rhythm Sessions, San Francisco, USA May 2016.
4. GJ Wynn, S Panikker, M Morgan, M Hall, J Waktare, V Markides, W Hussain, TV
Salukhe, S Modi, JWE. Jarman, DG. Jones, RL Snowdon, D Todd, T Wong, D Gupta.
Effect of linear ablation in substrate-based AF: Results of the Substrate Modification with
Ablation and antiarrhythmic drugs in Non-Permanent Atrial Fibrillation Trial. Late
Breaking Clinical Trials. Heart Rhythm Sessions, Boston, USA May 2015
ORAL PRESENTATIONS:
5. A. Hussein, M. Das, I. Asfour, M. Morgan, C. Ronayne, M. Shaw, R. Snowdon, D.
Gupta. Prospective Use of Ablation Index Targets Improves Clinical Outcomes
following Ablation for Atrial Fibrillation. EHRA Europace Sessions, Vienna June 2017
6. A. Hussein, M. Das, I. Asfour, M. Morgan, C. Ronayne, M. Shaw, R. Snowdon, D.
Gupta. Ablation Index-Guided Pulmonary Vein Isolation For Atrial Fibrillation May
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Improve Clinical outcomes In Comparison To Contact Force-Guided Ablation. Heart
Rhythm Congress, Birmingham, Oct 2016. Europace 2016; 18(1 Suppl 2): 33
7. CM Pearman, D Todd, R King, M Hall, S Modi, N Mediratta, D Gupta. The Procedural
Complication Rates And Short-Term Success Rates Of Thoracoscopic AF Ablation
During The Institutional Learning Curve. Heart Rhythm Congress, Birmingham, Oct
2016. Europace 2016;18(1 Suppl 2): 34
POSTER PRESENTATIONS:
8. B Maille, A Hussein, V Chaturvedi, M Morgan, C Ronayne, R Snowdon, D Gupta.
Reverse Remodelling of the Left Atrium occurs early after Catheter ablation for Persistent
Atrial Fibrillation. EHRA Europace Sessions, Vienna June 2017
9. Hussein A, Das M, Wynn GJ, Morgan M, Waktare JEP, Todd DM, Hall MCS, Snowdon
RL, Modi S, Gupta D.The Relationship Between The Effective Refractory Period Of
Reconnected Pulmonary Veins At Repeat Electrophysiology Study And Recurrence Of
Atrial Tachycarrhythmia Beyond One Month After Pulmonary Vein Isolation. Heart
Rhythm Congress, Birmingham, Oct 2016. Europace 2016;18(1 Suppl 2): 50
10. CM Pearman, J Parry, L Garth, J Chapman, D Todd, J Hobbs, S Modi, J Waktare, M
Hall, D Gupta, R Snowdon. Patients Undergoing SVT Ablation Have A High Incidence
Of Secondary Arrhythmia On Follow Up: Implications For Pre-Procedure Counselling.
Heart Rhythm Congress, Birmingham, Oct 2016. Europace 2016;18(1 Suppl 2): 122
11. Y Saeed, A Hussein, WV Ding, L McLenghan, M Meah, Wynn GJ, Waktare JEP, Todd
DM, Hall MCS, Snowdon RL, Modi S, Gupta D. The Impact of Simple Protocol
Changes in Improving Safety of Catheter Ablation for Atrial Fibrillation: Experience
from a Tertiary Centre in England. EHRA Europace Sessions, Nice June 2016 Europace
2016; 18(1 Suppl 1) 75
12. S Bartoletti, P Velavan, J Barclay, A Khalatbari, N Sharma, L Morrison, T Fairbairn, D
Gupta. Left Atrial Appendage Occlusion for Stroke Prevention in Atrial Fibrillation:
Contemporary Commissioning Through Evaluation Experience from the United
Kingdom. EHRA Europace Sessions, Nice June 2016. Europace 2016;18(1 Suppl 1) 86
13. Y Saeed, A Hussein, WV Ding, L McLenghan, M Meah, Wynn GJ, Waktare JEP, Todd
DM, Hall MCS, Snowdon RL, Modi S, Gupta D. Improving Safety and Clinical
Outcomes for Atrial Fibrillation Ablation: Should Our Threshold for Referral and for
Intervention Become Lower? British Cardiac Society sessions, Manchester, June 2016
Heart 102(Suppl 6):A46-A46
14. S Bartoletti, P Velavan, J Barclay, A Khalatbari, N Sharma, L Morrison, T Fairbairn, D
Gupta. Left Atrial Appendage Occlusion for Stroke Prevention in Atrial Fibrillation:
Contemporary Experience from a Commissioning Through Evaluation Site. British
Cardiac Society sessions, Manchester, June 2016. Heart 102(Suppl 6):A45-A46
15. Das M, Wynn GJ, Morgan M, Lodge B, Waktare JEP, Todd DM, Hall MCS, Snowdon
RL, Modi S, Gupta D. Re-ablated sites of acute reconnection after pulmonary vein
isolation do not predict sites of late reconnection at repeat electrophysiology study. Heart
Rhythm Sessions, San Francisco, USA May 2016. Heart Rhythm 2015, 12(5S):S121.
16. Das M, Wynn GJ, Morgan M, Lodge B, Waktare JEP, Todd DM, Hall MCS, Snowdon
RL, Modi S, Gupta D. Ablation Index predicts sites of reconnection at repeat
electrophysiology study following pulmonary vein isolation. Heart Rhythm Sessions, San
Francisco, USA May 2016. Heart Rhythm 2015, 12(5S):S362.
17. M Das, M Duytschaever, D Gupta, P Lukac, J Sorrel, T Phlips, AS Jadidi, H Nakagawa
Ablation Index Predicts Sites of Acute Reconnection after Pulmonary Vein Isolation
(PVI): a Multi-Center Retrospective Analysis. Heart Rhythm Sessions, San Francisco,
USA May 2016. Heart Rhythm 2015, 12(5S):S86
18. Das M, Piddock N, Wynn GJ, Morgan M, Lodge B, Waktare JEP, Todd DM, Hall MCS,
Snowdon RL, Modi S, Gupta D. Low impedance drop predicts sites of acute
reconnection following pulmonary vein isolation. Heart Rhythm Sessions, San Francisco,
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USA May 2016. Heart Rhythm 2015, 12(5S):S445
Current Research Projects
1. VISTAX study (Clinicaltrials.gov: NCT03062046): International Multicenter Study
at 15 European hospitals. Chief Investigator
2. Pulmonary vein Reconnection following Ablation Index-guided ablation: a
Success Evaluation (PRAISE) (Clinicaltrials.gov: NCT02628730): International
multi-centre trial. Chief Investigator
3. Catheter ablation vs Surgical Ablation for AF (CASA-AF) (Clinicaltrials.gov:
NCT02755688): NIHR funded 3 centre trial with Royal Brompton and Harefield
Hospitals, London. Principal Investigator
4. Amplatzer Amulet LAA Occluder trial. (Clinicaltrials.gov: NCT02879448).
International multicenter trial. Principal Investigator
Educational Activities (past 24 months only)
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Reviewer for Scientific Journals: I am a manuscript reviewer for the following journals
o Heart (Impact Factor, 2016: 5.6)
o Europace (Impact Factor, 2016: 5.9)
o Journal of the American College of Cardiology: Arrhythmia and Electrophysiology
Member of Scientific committee, Heart Rhythm Congress from 2014 to date
Head of AFA sessions, and assessor for abstracts at Heart Rhythm Congress: 2014 till date
I have conceived, organised and chaired the first two annual editions of the ‘North West AF and
Stroke Symposium’ in Liverpool in May 2016 and April 2017.
Invited Talks at National and International Scientific Conferences (past 24 months only)
1. European Heart Rhythm Association Europace-Cardiostim, Vienna 18-21 June 2017: ‘Debate:
Cryoablation should be first choice in persistent atrial fibrillation – Contra’.
2. European Heart Rhythm Association Europace-Cardiostim, Vienna 18-21 June 2017: ‘The
Impact of Contact Force on Procedural Outcome’.
3. 16th Atrial Fibrillation symposium, Hague, Netherlands, 23-24 March 2017: ‘Randomised trials
of Contact Force efficacy: a critical look at the literature’.
4. 7th Global Left Atrial Appendage Occlusion Summit, Copenhagen, 3 Feb 2017: ‘Vascular
complications: how to best avoid?’
5. A year in Cardiology: a British Cardiac Society Symposium, Royal College of Physicians,
London, 16 Dec 2016: ‘Electrophysiology: what did 2016 bring?’
6. Heart Rhythm Congress, Birmingham, UK 10-12 Oct 2016: ‘How do you keep ablations on
track’
7. Heart Rhythm Congress, Birmingham, UK 11 Oct 2016: ‘LAA Occlusion in the UK: what has 2
years of Commissioning through Evaluation taught us?’
8. New Swiss Horizons Meeting, Lenzerheide, Switzerland. 24 Sep 2016: ‘Use of Ablation Index
targets in AF ablation’.
9. Late Breaking Clinical Trials, Heart Rhythm Society Sessions, San Francisco May 2016:
‘Pulmonary vein re-isolation as a routine strategy- a success rate evaluation: The PRESSURE
trial’
10. 15th Atrial Fibrillation symposium, Rome 17-18 Mar 2016: ‘Extracardiac neural injury with AF
ablation.’
11. 13th Biannual Dead sea EP symposium, Tel-Aviv 7-9 Mar 2016: ‘Debate: Only PV Isolation is
Needed for Persistent AF: PRO’
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12. 13th Biannual Dead sea EP symposium, Tel-Aviv 7-9 Mar 2016: ‘The Utility and High
Reproducibility of a Novel Ablation Strategy’
13. 14th Biannual edition of the Venice Arrhythmias, Venice, Italy 16-18 Oct 2015: ‘Mapping and
ablation in Atrial Fibrillation: how can we evaluate lesion formation?’
14. Heart Rhythm Congress, Birmingham, UK 6-8 Oct 2015: ‘How to choose your ablation tool for
PVI? Are considerations of procedural efficacy and lab work-flow at cross-purposes?’
15. Heart Rhythm Congress, Birmingham, UK 6-8 Oct 2015: ‘Left atrial appendage Occlusion:
where does it sit amongst other preventive measures of stroke?’
16. Heart Failure and Co-morbidities: Symposium at the Royal College of General Practitioners, 24
June 2016: ‘Implementing effective AF treatment and anticoagulation in the NHS in 2016’
17. Annual Conference of the British Association of Cardiac Prevention and Rehabilitation, 2 Oct
2015: ‘New Horizons in AF management’
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