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BRCA1 and BRCA2 Breast Cancer Research Study for Advanced Hereditary Breast Cancer Do you or someone you know have metastatic or locally advanced breast cancer that is BRCA-associated? The Brocade3 study is a research study evaluating the safety and effectiveness of an investigational, oral medication in addition to treatment with chemotherapy for patients with metastatic or locally advanced BRCA-associated breast cancer. Study volunteers must meet the following criteria: • Be ages 18 or older • Have metastatic breast cancer or locally advanced breast cancer for which local therapy (surgery or radiation) is not appropriate • Have a BRCA1 or BRCA2 mutation • Not be pregnant or breastfeeding • Must be HER2-negative • Other criteria apply Compensation for travel may be available. For more information, ask your doctor about the BROCADE3 Study or visit www.Brocade3Study.com to see if you may qualify