Survey
* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project
Chapter 14 The Digestive System and Body Metabolism Lecture Presentation by Patty Bostwick-Taylor Florence-Darlington Technical College © 2015 Pearson Education, Inc. The Digestive System Functions Ingestion—taking in food Digestion—breaking food into nutrient molecules Absorption—movement of nutrients into the bloodstream Defecation—elimination of indigestible waste © 2015 Pearson Education, Inc. Organs of the Digestive System Two main groups of organs Alimentary canal (gastrointestinal or GI tract)— performs the whole menu of digestive functions as it propels the foodstuffs along its tract These organs ingest, digest, absorb, defecate Accessory digestive organs- Assist the process of digestive breakdown in various ways. Includes teeth, tongue, and other large digestive organs © 2015 Pearson Education, Inc. Figure 14.1 The human digestive system: Alimentary canal and accessory organs. Mouth (oral cavity) Tongue Parotid gland Sublingual gland Submandibular gland Salivary glands Pharynx Esophagus Stomach Pancreas (Spleen) Liver Gallbladder Small intestine Duodenum Jejunum Ileum Anus © 2015 Pearson Education, Inc. Transverse colon Descending colon Ascending colon Cecum Sigmoid colon Rectum Appendix Anal canal Large intestine Organs of the Alimentary Canal The alimentary canal ( GI Tract) is a continuous, coiled, hollow tube that runs through the ventral cavity from stomach to anus: Mouth Pharynx Esophagus Stomach Small intestine Large intestine Anus ( the terminal opening of the large intestine) © 2015 Pearson Education, Inc. Mouth (Oral Cavity) Anatomy of the mouth The mouth (oral cavity)—mucous membrane–lined cavity Lips (labia)—protect the anterior opening Cheeks—form the lateral walls Hard palate—forms the anterior roof Soft palate—forms the posterior roof Uvula—fleshy projection of the soft palate © 2015 Pearson Education, Inc. Mouth (Oral Cavity) Anatomy of the mouth (continued) Vestibule—space between lips externally and teeth and gums internally Oral cavity proper—area contained by the teeth Tongue—attached at hyoid bone and styloid processes of the skull, and by the lingual frenulum to the floor of the mouth © 2015 Pearson Education, Inc. Mouth (Oral Cavity) Anatomy of the mouth (continued) Tonsils Palatine—located at posterior end of oral cavity Lingual—located at the base of the tongue © 2015 Pearson Education, Inc. Figure 14.2a Anatomy of the mouth (oral cavity). Nasopharynx Hard palate Oral cavity Soft palate Lips (labia) Palatine tonsil Vestibule Lingual tonsil Lingual frenulum Tongue Hyoid bone Trachea (a) © 2015 Pearson Education, Inc. Uvula Oropharynx Epiglottis Laryngopharynx Esophagus Figure 14.2b Anatomy of the mouth (oral cavity). Upper lip Gingivae (gums) Hard palate Soft palate Uvula Palatine tonsil Oropharynx Tongue (b) © 2015 Pearson Education, Inc. Mouth Functions of the mouth Mastication (chewing) of food Tongue mixes masticated food with saliva Tongue initiates swallowing Taste buds on the tongue allow for taste © 2015 Pearson Education, Inc. Pharynx Food passes from the mouth posteriorly into the: Oropharynx—posterior to oral cavity Laryngopharynx—below the oropharynx and continuous with the esophagus The pharynx serves as a passageway for food, fluids, and air © 2015 Pearson Education, Inc. Esophagus (Gullet) Anatomy About 10 inches long Runs from pharynx to stomach through the diaphragm Physiology Conducts food by peristalsis (slow rhythmic squeezing) to the stomach Passageway for food only © 2015 Pearson Education, Inc. Stomach The stomach is a C-shaped organ located on the left side of the abdominal cavity Food enters at the cardioesophageal sphincter from the esophagus Food empties into the small intestine at the pyloric sphincter (valve) © 2015 Pearson Education, Inc. Stomach Regions of the stomach Cardial part (cardia)—near the heart Fundus—expanded portion lateral to the cardiac region Body—midportion Pylorus—funnel-shaped terminal end © 2015 Pearson Education, Inc. Stomach Stomach can stretch and hold 4 L (1 gallon) of food when full Rugae—internal folds of the mucosa present when the stomach is empty External regions Lesser curvature—concave medial surface Greater curvature—convex lateral surface © 2015 Pearson Education, Inc. Figure 14.4a Anatomy of the stomach. Cardia Fundus Esophagus Muscularis externa • Longitudinal layer • Circular layer • Oblique layer Pylorus Serosa Body Lesser curvature Rugae of mucosa Greater curvature Duodenum (a) © 2015 Pearson Education, Inc. Pyloric sphincter (valve) Pyloric antrum Figure 14.4b Anatomy of the stomach. Fundus Body Rugae of mucosa (b) © 2015 Pearson Education, Inc. Pyloric sphincter Pyloric antrum Stomach Functions of the stomach Temporary storage tank for food Site of food breakdown Chemical breakdown of protein begins Delivers chyme (processed food) to the small intestine © 2015 Pearson Education, Inc. Small Intestine The body’s major digestive organ Chemical digestion begins in the small intestine Longest portion of the alimentary tube (2–4 m or 7–13 feet in a living person) Site of nutrient absorption into the blood Muscular tube extending from the pyloric sphincter to the ileocecal valve Suspended from the posterior abdominal wall © 2015 Pearson Education, Inc. Figure 14.5 Peritoneal attachments of the abdominal organs. Diaphragm Falciform ligament Liver Spleen Gallbladder Stomach Visceral peritoneum Greater omentum Lesser omentum Pancreas Duodenum Transverse colon Mesenteries Parietal peritoneum Small intestine Peritoneal cavity Uterus Large intestine Cecum Rectum Anus Urinary bladder (a) © 2015 Pearson Education, Inc. (b) Small Intestine Subdivisions Duodenum Attached to the stomach Curves around the head of the pancreas Jejunum Attaches anteriorly to the duodenum Ileum Extends from jejunum to large intestine Meets the large intestine at the ileocecal valve © 2015 Pearson Education, Inc. Large Intestine Larger in diameter, but shorter in length at 1.5 m, than the small intestine Extends from the ileocecal valve to the anus Subdivisions: Cecum Appendix Colon Rectum Anal canal © 2015 Pearson Education, Inc. Large Intestine Anatomy Cecum—saclike first part of the large intestine Appendix Accumulation of lymphoid tissue that sometimes becomes inflamed (appendicitis) Hangs from the cecum © 2015 Pearson Education, Inc. Large Intestine Anatomy Colon Ascending—travels up right side of abdomen Transverse—travels across the abdominal cavity Descending—travels down the left side Sigmoid—S-shaped region; enters the pelvis Sigmoid colon, rectum, and anal canal are located in the pelvis © 2015 Pearson Education, Inc. Large Intestine Anatomy Anal canal ends at the anus Anus—opening of the large intestine The large intestine delivers undigestible food residues to the body’s exterior © 2015 Pearson Education, Inc. Figure 14.8 The large intestine. Left colic (splenic) flexure Transverse mesocolon Right colic (hepatic) flexure Transverse colon Haustrum Descending colon Ascending colon Cut edge of mesentery Ileum (cut) Ileocecal valve Teniae coli Sigmoid colon Cecum Appendix Rectum Anal canal © 2015 Pearson Education, Inc. External anal sphincter Accessory Digestive Organs Teeth Salivary glands Pancreas Liver Gallbladder © 2015 Pearson Education, Inc. Teeth Teeth masticate (chew) food into smaller fragments Humans have two sets of teeth during a lifetime: 1. Deciduous (also known as baby or “milk”) teeth A baby has 20 teeth by age 2 First teeth to appear are the lower central incisors © 2015 Pearson Education, Inc. Teeth 2. Permanent teeth Replace deciduous teeth between the ages of 6 and 12 A full set is 32 teeth, but some people do not have wisdom teeth If they do emerge, the wisdom teeth appear between ages of 17 and 25 © 2015 Pearson Education, Inc. Classification of Teeth Incisors—cutting Canines (eyeteeth)—tearing or piercing Premolars (bicuspids)—grinding Molars—grinding © 2015 Pearson Education, Inc. Figure 14.9 Human deciduous and permanent teeth. Incisors Central (6–8 mo) Lateral (8–10 mo) Canine (eyetooth) (16–20 mo) Molars First molar (10–15 mo) Second molar (about 2 yr) Incisors Central (7 yr) Lateral (8 yr) Canine (eyetooth) (11 yr) Premolars (bicuspids) First premolar (11 yr) Second premolar (12–13 yr) Molars First molar (6–7 yr) Second molar (12–13 yr) Third molar (wisdom tooth) (17–25 yr) © 2015 Pearson Education, Inc. Deciduous (milk) teeth Permanent teeth Regions of a Tooth Two major regions of a tooth 1. Crown-exposed part of tooth above the gum Note: The neck is a connector between the crown and root. Region in contact with the gum Connects crown to root 2. Root- embedded in the maxilla or the mandible and are covered by gums © 2015 Pearson Education, Inc. Figure 14.10 Longitudinal section of a molar. Enamel Dentin Crown Neck Pulp cavity (contains blood vessels and nerves) Gum (gingiva) Cement Root Root canal Periodontal membrane (ligament) Bone © 2015 Pearson Education, Inc. Salivary Glands Three pairs of salivary glands empty secretions into the mouth 1. Parotid glands Found anterior to the ears 2. Submandibular glands 3. Sublingual glands Both submandibular and sublingual glands empty saliva into the floor of the mouth through small ducts © 2015 Pearson Education, Inc. Figure 14.1 The human digestive system: Alimentary canal and accessory organs. Mouth (oral cavity) Tongue Parotid gland Sublingual gland Submandibular gland Salivary glands Pharynx Esophagus Stomach Pancreas (Spleen) Liver Gallbladder Small intestine Duodenum Jejunum Ileum Anus © 2015 Pearson Education, Inc. Transverse colon Descending colon Ascending colon Cecum Sigmoid colon Rectum Appendix Anal canal Large intestine Salivary Glands Saliva Mixture of mucus and serous fluids Helps to moisten and bind food together into a mass called a bolus © 2015 Pearson Education, Inc. Pancreas Soft, pink, triangular gland that extends across the abdomen from spleen to duodenum Produces a wide spectrum of digestive enzymes that break down all categories of food Secretes enzymes into the duodenum Hormones produced by the pancreas Insulin Glucagon © 2015 Pearson Education, Inc. Figure 14.1 The human digestive system: Alimentary canal and accessory organs. Mouth (oral cavity) Tongue Parotid gland Sublingual gland Submandibular gland Salivary glands Pharynx Esophagus Stomach Pancreas (Spleen) Liver Gallbladder Small intestine Duodenum Jejunum Ileum Anus © 2015 Pearson Education, Inc. Transverse colon Descending colon Ascending colon Cecum Sigmoid colon Rectum Appendix Anal canal Large intestine Figure 14.6 The duodenum of the small intestine and related organs. Right and left hepatic ducts from liver Cystic duct Common hepatic duct Bile duct and sphincter Accessory pancreatic duct Pancreas Gallbladder Jejunum Duodenal papilla Hepatopancreatic ampulla and sphincter © 2015 Pearson Education, Inc. Main pancreatic duct and sphincter Duodenum Liver Largest gland in the body Located on the right side of the body under the diaphragm Consists of four lobes suspended from the diaphragm and abdominal wall Connected to the gallbladder via the common hepatic duct © 2015 Pearson Education, Inc. Figure 14.1 The human digestive system: Alimentary canal and accessory organs. Mouth (oral cavity) Tongue Parotid gland Sublingual gland Submandibular gland Salivary glands Pharynx Esophagus Stomach Pancreas (Spleen) Liver Gallbladder Small intestine Duodenum Jejunum Ileum Anus © 2015 Pearson Education, Inc. Transverse colon Descending colon Ascending colon Cecum Sigmoid colon Rectum Appendix Anal canal Large intestine Liver Bile is produced by cells in the liver Bile leaves the liver through the common hepatic duct and enters duodenum through the bile duct Bile is a yellow-green, watery solution that helps with digestion. Breaks down fats into fatty acid. Contains water, body salts (potassium and sodium) © 2015 Pearson Education, Inc. Gallbladder Sac found in shallow fossa of liver When no digestion is occurring, bile backs up the cystic duct for storage in the gallbladder Gallstones are crystallized cholesterol, which can cause blockages © 2015 Pearson Education, Inc. Figure 14.1 The human digestive system: Alimentary canal and accessory organs. Mouth (oral cavity) Tongue Parotid gland Sublingual gland Submandibular gland Salivary glands Pharynx Esophagus Stomach Pancreas (Spleen) Liver Gallbladder Small intestine Duodenum Jejunum Ileum Anus © 2015 Pearson Education, Inc. Transverse colon Descending colon Ascending colon Cecum Sigmoid colon Rectum Appendix Anal canal Large intestine Figure 14.6 The duodenum of the small intestine and related organs. Right and left hepatic ducts from liver Cystic duct Common hepatic duct Bile duct and sphincter Accessory pancreatic duct Pancreas Gallbladder Jejunum Duodenal papilla Hepatopancreatic ampulla and sphincter © 2015 Pearson Education, Inc. Main pancreatic duct and sphincter Duodenum Functions of the Digestive System Major functions of the digestive system are summarized as: Digestion Absorption We will cover 6 more specific processes next © 2015 Pearson Education, Inc. Functions of the Digestive System 1. Ingestion—placing of food into the mouth 2. Propulsion—movement of foods from one region of the digestive system to another Peristalsis—alternating waves of contraction and relaxation that squeezes food along the GI tract Segmentation—movement of materials back and forth to foster mixing in the small intestine © 2015 Pearson Education, Inc. Functions of the Digestive System 3. Food breakdown: mechanical breakdown Examples: Mixing of food in the mouth by the tongue Churning of food in the stomach Segmentation in the small intestine Mechanical digestion prepares food for further degradation by enzymes © 2015 Pearson Education, Inc. Functions of the Digestive System 4. Food breakdown: digestion Digestion occurs when enzymes chemically break down large molecules into their building blocks Each major food group uses different enzymes Carbohydrates are broken to monosaccharides (simple sugars) Proteins are broken to amino acids Fats are broken to fatty acids © 2015 Pearson Education, Inc. Functions of the Digestive System 5. Absorption End products of digestion are absorbed in the blood or lymph Food must enter mucosal cells and then into blood or lymph capillaries 6. Defecation Elimination of indigestible substances from the GI tract in the form of feces © 2015 Pearson Education, Inc. Figure 14.11 Schematic summary of gastrointestinal tract activities. Ingestion Mechanical breakdown • Chewing (mouth) • Churning (stomach) • Segmentation (small intestine) Digestion Food Pharynx Esophagus Propulsion • Swallowing (oropharynx) • Peristalsis (esophagus, stomach, small intestine, large intestine) Stomach Absorption Lymph vessel Small intestine Blood vessel Large intestine Mainly H2O Feces Defecation © 2015 Pearson Education, Inc. Anus Activities Occurring in the Mouth, Pharynx, and Esophagus Food ingestion and breakdown Food is placed into the mouth Physically broken down by chewing Mixed with saliva Essentially, no food absorption occurs in the mouth © 2015 Pearson Education, Inc. Activities Occurring in the Mouth, Pharynx, and Esophagus Food propulsion—swallowing and peristalsis Pharynx and esophagus have no digestive function Serve as passageways to the stomach Pharynx functions in swallowing Two phases of swallowing: 1. Buccal phase 2. Pharyngeal-esophageal phase © 2015 Pearson Education, Inc. Activities Occurring in the Mouth, Pharynx, and Esophagus Food propulsion—swallowing and peristalsis (continued) 1. Buccal phase Voluntary Occurs in the mouth Food is formed into a bolus The bolus is forced into the pharynx by the tongue © 2015 Pearson Education, Inc. Activities Occurring in the Mouth, Pharynx, and Esophagus Food propulsion—swallowing and peristalsis (continued) 2. Pharyngeal-esophogeal phase (continued) Involuntary transport of the bolus by peristalsis Peristalsis moves the bolus toward the stomach The cardioesophageal sphincter is opened when food presses against it © 2015 Pearson Education, Inc. Figure 14.14a Swallowing. Bolus of food Tongue Pharynx Upper Epiglottis esophageal up sphincter Glottis (lumen) of larynx Esophagus Trachea (a) Upper esophageal sphincter contracted © 2015 Pearson Education, Inc. Figure 14.14b Swallowing. Uvula Bolus Epiglottis down Larynx up Esophagus (b) Upper esophageal sphincter relaxed © 2015 Pearson Education, Inc. Figure 14.14c Swallowing. Bolus (c) Upper esophageal sphincter contracted © 2015 Pearson Education, Inc. Figure 14.14d Swallowing. Relaxed muscles Cardioesophageal sphincter open (d) Cardioesophageal sphincter relaxed © 2015 Pearson Education, Inc. Activities in the Stomach Food breakdown Food propulsion 1. Peristalsis: Waves of peristalsis occur from the fundus to the pylorus, forcing food past the pyloric sphincter 2. Grinding: The pylorus meters out chyme into the small intestine (3 ml at a time) 3. Retropulsion: Peristaltic waves close the pyloric sphincter, forcing content back into the stomach. © 2015 Pearson Education, Inc. Figure 14.15 Peristaltic waves in the stomach. Pyloric valve closed Pyloric valve slightly opened 1 Propulsion: Peristaltic waves move from the fundus toward the pylorus. 2 Grinding: The most vigorous peristalsis and mixing action occur close to the pylorus. The pyloric end of the stomach acts as a pump that delivers small amounts of chyme into the duodenum. © 2015 Pearson Education, Inc. Pyloric valve closed 3 Retropulsion: The peristaltic wave closes the pyloric valve, forcing most of the contents of the pylorus backward into the stomach. Activities of the Small Intestine Food breakdown and absorption Intestinal enzymes function to: Break double sugars into simple sugars Complete some protein digestion Pancreatic enzymes play the major role in the digestion of fats, proteins, and carbohydrates © 2015 Pearson Education, Inc. Activities of the Large Intestine Food breakdown and absorption Remaining materials are eliminated via feces Feces contains: Undigested food residues Mucus Bacteria Water © 2015 Pearson Education, Inc. POP QUIZ What happen during buccal stage of swallowing? How does segmentation differ from peristalsis in terms of moving substances along the GI tract? What does it mean when we say that food “went down the wrong tube”? Differentiate between mechanical and chemical breakdown? What is the name of the end part of the stomach that connect to the small intestine. © 2015 Pearson Education, Inc. Nutrition and Metabolism Most foods are used as metabolic fuel Foods are oxidized and transformed into adenosine triphosphate (ATP) ATP is chemical energy that drives cellular activities Energy value of food is measured in kilocalories (kcal) or Calories (C) © 2015 Pearson Education, Inc. Nutrition Nutrient—substance used by the body for growth, maintenance, and repair Major nutrients Carbohydrates Lipids Proteins Water Minor nutrients Vitamins Minerals © 2015 Pearson Education, Inc. Figure 14.17 Two visual food guides. White rice, white bread, potatoes, pasta, sweets: use sparingly Dairy or calcium supplement: 1–2 servings Red meat, butter: use sparingly Fish, poultry, eggs: 0–2 servings Nuts, legumes: 1–3 servings Fruits: 2–3 servings Vegetables in abundance Whole-grain foods at most meals Plant oils at most meals Daily exercise and weight control (a) Healthy Eating Pyramid (b) USDA’s MyPlate © 2015 Pearson Education, Inc. Nutrition A diet consisting of foods from the five food groups normally guarantees adequate amounts of all the needed nutrients The five food groups are summarized next in Table 14.2 © 2015 Pearson Education, Inc. Table 14.2 Five Basic Food Groups and Some of Their Major Nutrients (1 of 2). © 2015 Pearson Education, Inc. Table 14.2 Five Basic Food Groups and Some of Their Major Nutrients (2 of 2). © 2015 Pearson Education, Inc. Dietary Sources of Major Nutrients Carbohydrates Dietary carbohydrates are sugars and starches Most are derived from fruits, grains, vegetables and milk products © 2015 Pearson Education, Inc. Dietary Sources of Major Nutrients Lipids Saturated fats from animal products (meats) Unsaturated fats from nuts, seeds, and vegetable oils Cholesterol from egg yolk, meats, and milk products (dairy products) © 2015 Pearson Education, Inc. Dietary Sources of Major Nutrients Proteins Complete proteins—contain all essential amino acids Most are from animal products (eggs, milk, meat, poultry, and fish) Essential amino acids: those that the body cannot make and must be obtained through diet Beans also have proteins, but the proteins are incomplete © 2015 Pearson Education, Inc. Dietary Sources of Major Nutrients Vitamins Organic nutrients of various forms that the body requires in small amounts Found mainly in fruits and vegetables © 2015 Pearson Education, Inc. Dietary Sources of Major Nutrients Minerals Mainly important for enzyme activity Foods richest in minerals: vegetables, milk, and some meats Iron is important for making hemoglobin Calcium is important for building bone, blood clotting, and secretory activities © 2015 Pearson Education, Inc. Do Now What is the name of the rhythmic contractions in the esophagus? Identify the three types of teeth present in your mouth and the function of each type. List the six nutrient categories Define nutrient and kilocalories © 2015 Pearson Education, Inc. Metabolism Metabolism is all of the chemical reactions necessary to maintain life Catabolism—the breakdown of molecules to obtain energy Anabolism—larger molecules are built from smaller ones © 2015 Pearson Education, Inc. Carbohydrate Metabolism Carbohydrates are the body’s preferred source to produce cellular energy (ATP) Glucose (blood sugar) Major breakdown product of carbohydrate digestion Fuel used to make ATP © 2015 Pearson Education, Inc. Carbohydrate Metabolism Cellular respiration As glucose is oxidized, carbon dioxide, water, and ATP are formed © 2015 Pearson Education, Inc. Figure 14.19 Summary equation for cellular respiration. C6H12O6 Glucose © 2015 Pearson Education, Inc. + 6 O2 Oxygen gas 6 CO2 Carbon dioxide + 6 H2O Water + ATP Energy Carbohydrate Metabolism Events of three main metabolic pathways of cellular respiration 1. Glycolysis (2 ATP) Occurs in the cytosol glucose molecule is split into two pyruvic acid molecules and produce ATP 2. Krebs cycle (2 ATP) Occurs in the mitochondrion 3. Electron transport chain (28 ATP) © 2015 Pearson Education, Inc. Carbohydrate Metabolism Hyperglycemia—excessively high levels of glucose in the blood Excess glucose is stored in body cells as glycogen or converted to fat Hypoglycemia—low levels of glucose in the blood © 2015 Pearson Education, Inc. Fat Metabolism Fats Insulate the body Protect organs Build some cell structures (membranes and myelin sheaths) Provide reserve energy Excess dietary fat is stored in subcutaneous tissue and other fat depots © 2015 Pearson Education, Inc. Fat Metabolism When carbohydrates are in limited supply, more fats are oxidized to produce ATP Excessive fat breakdown causes blood to become acidic (acidosis or ketoacidosis) Breath has a fruity odor Common with: “No carbohydrate” diets Uncontrolled diabetes mellitus Starvation © 2015 Pearson Education, Inc. Protein Metabolism Proteins are the main tissue builders in the body Ingested proteins are broken down into amino acids Amino acids are oxidized to form ATP mainly when other fuel sources are not available © 2015 Pearson Education, Inc. The Central Role of the Liver in Metabolism Liver is the body’s key metabolic organ Roles in digestion: Manufactures bile Detoxifies drugs and alcohol Produces cholesterol, blood proteins (albumin and clotting proteins) Plays a central role in metabolism Liver can regenerate if part of it is damaged or removed © 2015 Pearson Education, Inc. The Central Role of the Liver in Metabolism To maintain homeostasis of blood glucose levels, the liver performs: Glycogenesis—“glycogen formation” Glucose molecules are converted to glycogen and stored in the liver Glycogenolysis—“glycogen splitting” Glucose is released from the liver after conversion from glycogen Gluconeogenesis—“formation of new sugar” Glucose is produced from fats and proteins © 2015 Pearson Education, Inc. Body Energy Balance Energy intake = Total energy output (heat + work + energy storage) Energy intake is the energy liberated during food oxidation Energy produced during glycolysis, Krebs cycle, and the electron transport chain Energy output Energy we lose as heat (60%) Energy stored as fat or glycogen Body weight is usually relatively stable Energy intake and output remain about equal © 2015 Pearson Education, Inc. Body Energy Balance Interference with the body’s energy balance leads to: Obesity Malnutrition © 2015 Pearson Education, Inc. Metabolic Rate and Body Heat Production Nutrients yield different amounts of energy Energy value is measured in kilocalorie (kcal) Carbohydrates and proteins yield 4 kcal/gram Fats yield 9 kcal/gram © 2015 Pearson Education, Inc. Basal Metabolic Rate Basic metabolic rate (BMR)—amount of heat produced by the body per unit of time at rest Average BMR is about 60 to 72 kcal/hour for an average 70-kg (154-lb) adult © 2015 Pearson Education, Inc. Basal Metabolic Rate Factors that influence BMR Surface area—a small body usually has a higher BMR Gender—males tend to have higher BMRs Age—children and adolescents have higher BMRs © 2015 Pearson Education, Inc. Total Metabolic Rate (TMR) TMR—total amount of kilocalories the body must consume to fuel ongoing activities TMR increases dramatically with an increase in muscle activity TMR must equal calories consumed to maintain homeostasis and maintain a constant weight © 2015 Pearson Education, Inc.