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Understanding Drugs and Medicines Overview of Chapter • Learn what makes a drug a medicine • Why certain drugs are classified as drugs of abuse • Benefits of medicines when taken correctly • Risks of misusing medicines • Why certain drugs are addictive • How addiction can be avoided and treated Drugs Chapter 9: Section 1 Overview of Section • List three qualities that make a drug useful as a medicine. • Name the two sources of all drugs. • Identify four different types of medicines and their effects on the body. • Identify five different ways that drugs can enter the body. • Describe why some drugs are considered drugs of abuse. What Are Drugs? • A drug is any substance that causes a change in a person’s physical or psychological state. • Medicines are drugs used to cure, prevent, or treat illness or discomfort. • Good medicines have the following qualities: – Effectiveness—when a medicine is good at carrying out its task. – Safety—when used as directed. – Minor side effects—mild. Drugs of Abuse • Drugs of abuse are drugs that people take for mindaltering effects that have no medical purpose. • Drugs of abuse can change the way your brain works in ways that are unhealthy and dangerous. • Drugs that affect your brain can change your behavior over time and lead to addiction and longterm health problems. Where Do Drugs Come From? • All drugs are chemicals that come from one of two sources: – Naturals sources, such as plants, animals, or fungi – Laboratories Types of Medicine • A prescription is a written order from a doctor for a specific medicine. • Over-the-counter (OTC) medicines can be bought without a prescription. America’s Most Popular Drug • About 80-90% of the American population consume caffeine in one form or another • The most widely consumed drug • An addictive drug • Can lead to physical dependence Types of Medicines • Analgesic – Relives pain • Antihistamine – Helps relieve allergy symptoms • Antacid – Neutralizes • Antibiotic – Kills bacteria • Bronchodilator – Helps open air way • Steriod antiinflammatory – Reduces inflammation/itch on the skin • Sedative – Causes sleepiness How Drugs Enter The Body • Drugs can be taken into the body in the following ways: – – – – – – Implanted pumps Inhalation Injection Transdermal patches Ingestion Topical application Drugs as Medicines Objectives • Describe the process by which drugs are approved for medical use. • State two reasons why prescriptions are required for some medicines. • State two factors to consider when choosing overthe-counter (OTC) medicines. • Describe three problems that can occur when taking some medicines. • List six things you shoula do to be able to use medicines wisely Approving Drugs for Medical Use • The Food and Drug Administration (FDA) was created in 1906 to control the safety of food, drugs, and cosmetics in the United States. • The FDA uses an approval process for proving a drug is safe and effective. Some steps include: – – – – Chemical or cell-culture testing in laboratories Testing on animals Testing on human volunteers Clinical trials to compare to existing drugs Prescription Medicines • Prescription medications should only be taken with a doctor’s recommendation and supervision. • Taking someone else’s medication or failing to follow the prescription can be dangerous. Medicine Labels • Prescriptions include the following information: – – – – Dosage (how much you should take) When you should take the medicine How often you should take the medicine The length of time you should take the medicine • Many pharmacies will also give you a drug information sheet that includes: – Side effects – Known interactions with other medicines Over-the-counter (OTC) • Most OTC medicines are used for common illnesses, injuries, and disorders. • When choosing an OTC: – Decide what kind of OTC will work for you. – Decide whether you want a generic or brand-name medicine. They often have the same active ingredients but different inactive ingredients. – Read the labels. OTC Continued • Long-term use of OTC medicines can cover up more serious problems. • If symptoms persist, consult a doctor. • Herbal remedies and dietary supplements do not have to be approved by the FDA. • Because they may have not been thoroughly tested, herbal remedies and dietary supplements may not be safe or effective. Fact • The national institute on drug abuse estimates that in 1994, 4 million people aged 12 and older used prescription medicine for non-medical reasons Possible Problems with Medicines • Allergic reactions are the most serious risks to taking medicines. • Symptoms of anaphylactic shock include: – – – – – Itching all over the body Swelling, especially in the mouth or throat Wheezing or difficulty breathing A pounding heart Fainting and unconsciousness Possible Problems With Medicines-continued • Side effects are more common problems than medicine allergies. • Drug interactions occur when a drug reacts with another drug, food, or dietary supplement to increase or decrease the effect of one of the substances. • Labels on OTC packages or drug information sheets describe possible drug interactions and may also list potential side effects. Using Medicines Wisely 1. Make yourself part of your own healthcare team. 2. Be prepared to ask questions. 3. Learn the facts about any medicine you take. 4. Listen to your body. 5. It’s not always safe to suddenly stop taking a drug. 6. Speak up and enlist your parents’ help. Drugs and The Brain Objectives • Describe how drugs that affect the brain work. • State how drugs can affect a person’s emotions. • Describe how addiction can develop from experimentation. • Summarize the role of withdrawal in maintaining a drug addiction. • Describe why addiction is considered a treatable and avoidable disease. How Drugs That Affect the Brain Work • Information processing in the brain takes place at the connections between neurons, called synapses. • Signals are passed across synapses by chemicals called neurotransmitters. • Some drugs affect the way neurons communicate by acting like neurotransmitters, blocking neurotransmitters, or changing the amount of neurotransmitters. • These changes can affect our moods and emotions. • Serotonin. • Dopamine. • Epinephrine. • Antidepressants. Path To Addiction • Addiction is a condition in which a person can no longer control his or her drug use. • Most drugs of abuse activate the brain reward system, which releases chemicals that give pleasure. • Pleasure alone does not cause addiction. • People who become addicts usually start by experimenting, then more regular use leads to a series of changes on the path to addiction. • Brain reward system. • Collective name for sets of brain structures. Dependence • Physical-the state in which the body relies on a given drug in order to function normally. • Psychological-state of emotionally or mentally needing a drug in order to function normally. Addiction • Learning drug abuse behavior/attitude • Lose control of their behavior • Do not care about the consequences • Learns how to get them • Learns how to take them • How to lie and steal • Most important, learns to use drugs to deal with their emotional problems • Now classified as a brain disorder Withdrawal • Uncomfortable physical and psychological symptoms produced when a physically dependent drug user stops using drugs. • Characterized mostly by symptoms that are opposite to the drug’s effect. • Forces the users to take more of that drug to regain a “normal feeling.” Addiction is a Treatable Disease • Drug addiction is a brain disorder, and it is treatable. • Most communities offer a variety of treatment programs for addiction. • The best way to avoid addiction is to avoid drugs of abuse altogether. Facts/Figures • Three quarters of 16 yr olds do not drink of use pot • 98% of that does not use cocaine or heroin • 50% of 16 yr olds have never smoked a cigarette