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Syllabus neurobiology of feeding - 71162 Last update 03-07-2016 HU Credits: 2 Degree/Cycle: 2nd degree (Master) Responsible Department: nutrition sciences Academic year: 0 Semester: 2nd Semester Teaching Languages: Hebrew Campus: Rehovot Course/Module Coordinator: Prof Oren Froy Coordinator Email: [email protected] Coordinator Office Hours: by email Teaching Staff: Prof Oren Froy page 1 / 4 Course/Module description: The Organization of the Nervous System, The Cellular Components of the Nervous System, Nerve Cells, Neuroglial Cells, Neural Circuits, The Subdivisions of the Central Nervous System, The External Anatomy of the Brain: Some General Points, The Lateral Surface of the Brain, The Dorsal and Ventral Surfaces of the Brain, The Internal Anatomy of the Brain, The Internal Anatomy of the Cerebral Hemispheres and Diencephalon The Sympathetic Division of the Visceral Motor System, The Parasympathetic Division of the Visceral Motor System, The Enteric Nervous System Neurotransmitters, What Defines a Neurotransmitter?, Two Major Categories of Neurotransmitters, Neurons Often Release More Than One Transmitter, Neurotransmitter Synthesis, Packaging Neurotransmitters, Neurotransmitter Release and Removal, Acetylcholine, Glutamate, GABA and Glycine, The Biogenic Amines, The Biogenic Amines, ATP and Other Purines, Peptide Neurotransmitters, Endocannabinoids, Neurotransmitter Receptors and Their Effects, Cholinergic Receptors, Glutamate Receptors, GABA and Glycine Receptors, Serotonin Receptors, Purinergic Receptors, Catecholamine Receptors, Peptide Receptors Brain Metabolism, Circulation and Energy Metabolism of the Brain, BloodBrainCerebrospinal Fluid Barriers, Nutrition and Brain Function, Nutrition and Functional Neurochemistry, Nutrition and Structural Aspects of the Brain, Nutrition and Brain Development Hypothalamic Organization, Functions of the Limbic System, Role of the Ventromedial Hypothalamus in Feeding, Role of the Lateral Hypothalamus in Feeding, Role of Limbic Areas in Feeding, The Arcuate Nucleus is a Key Node of Hypothalamic Control of Energy Balance , Role of the Brain Stem in Feeding, Role of the Dorsomedial Hypothalamus in Energy Balance Feeding and Satiety Circuits, Melanocortin-4 Receptors Regulate Energy and Glucose Homeostasis, The Lateral Hypothalamus Links Coordinated Food Intake Control and Arousal, Central Nervous System Control Of Thermogenesis Hormonal Regulators Of The Brain-Gut-Adipose Axis, Adipostatic Factors, Leptin Is the Prototypical Regulator of Energy Homeostasis, Distribution of Leptin Receptors, The Role of Insulin and Glucose in Regulating Energy Homeostasis, Insulin Action in the Brain, Glucose Levels Are Sensed by Neurons in the Brain, POMC Neurons Sense Changes in Glucose Concentration, Satiety and Hunger Factors, Role of the Brain stem in Satiety/Hunger, Gut Peptides Involved in Satiety and Hunger, Cholecystokinin, PYY, Ghrelin, PreproglucagonDerived Peptides, GLP-1 and GLP-1R Neurons in the Central Nervous System, Amylin, Bariatric Surgery and the Role of the Gastrointestinal System in the Control page 2 / 4 of Energy Homeostasis Cytokines And Energy Balance, Neuroendocrine-Immune Interactions, Mechanisms of Cytokine Signaling in the Central Nervous System, Interaction of Cytokines with the Circumventricular Organs, Interactions of Cytokines at the Barriers of the Brain: The Requirement of Prostaglandins Entry of Cytokines into the Brain, Brain Regions Involved in the Cytokine Response Neuroendocrine Disorders of Energy Homeostasis, Leptin and Leptin Receptor Deficiency in Humans, Obesity resulting from Defective Melanocortin Signaling, Narcolepsy Circadian Rhythms, Effect of the Biological Clock on Metabolism, Effect of Redox on Circadian Rhythms, Projection from the SCN to Regions in Hypothalamus, Effect of SCN on Energy Balance, Body Temperature and Wakefulness Course/Module aims: To understand the connection between the nervous system and nutrition and metabolism. Learning outcomes - On successful completion of this module, students should be able to: To understand the connection between the nervous system and nutrition and metabolism. Attendance requirements(%): 0 Teaching arrangement and method of instruction: Lectures Course/Module Content: The Organization of the Nervous System, The Cellular Components of the Nervous System, Nerve Cells, Neuroglial Cells, Neural Circuits, The Subdivisions of the Central Nervous System, The External Anatomy of the Brain: Some General Points, The Lateral Surface of the Brain, The Dorsal and Ventral Surfaces of the Brain, The Internal Anatomy of the Brain, The Internal Anatomy of the Cerebral Hemispheres and Diencephalon page 3 / 4 Required Reading: 1) Basic Neurochemistry 7th ed. 2) Neuroscience exploring the brain 3rd ed. 3) Fundamental Neuroscience 3rd ed. 4) Williams Textbook of Endocrinology 11th ed. 5) Reviews in the medical literature (Pubmed) Additional Reading Material: - Course/Module evaluation: End of year written/oral examination 100 % Presentation 0 % Participation in Tutorials 0 % Project work 0 % Assignments 0 % Reports 0 % Research project 0 % Quizzes 0 % Other 0 % Additional information: None page 4 / 4 Powered by TCPDF (www.tcpdf.org)