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Download Chapter 12 Skeletal and Smooth Muscle part-2
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Completion of Skeletal Muscle and comparison to Smooth Muscle Outline Classification of Skeletal muscle Slow twitch versus fast twitch Oxidative versus glycolytic Skeletal Muscle Genetic Diseases Smooth Muscle Types of smooth muscle cells Smooth muscle contraction Smooth muscle relaxation Smooth muscle compared to Skeletal Muscle Classification of skeletal muscle Speed of contraction Resistance to Fatigue Which type of muscle fibers are used for these two activities? Pianist Fast Twitch Weight lifting Slow Twitch Muscular Disease Muscular Dystrophy Sex linked recessive Dystrophin is mutated Myasthenia Gravis Decreased number of acetylcholine receptors TYPES OF SMOOTH MUSCLE CELLS SMOOTH MUSCLE CONTRACTION NO SARCOMERES! Presence of Dense Bodies EXTRA CALCIUM STORAGE SITES SMOOTH MUSCLE CONTRACTION at the MOLECULAR LEVEL No sacromeres No troponin Look inside the smooth muscle cell Smooth Muscle Relaxation Comparisons: Smooth versus Skeletal Increase cytosolic calcium Increase of cytosolic calcium Calcium binds calmodulin Calcium binds troponin Ca++Calmodulin activates MLCK Alteration in troponin moves tropomyosin MLCK activates myosin ATPase Myosin binds actin Shortening Shortening
