Download Prof Andrew Leisewitz

Prof Andrew Leisewitz
Companion Animal Clinical Studies
[email protected]
Key Publications
Goddard A, Leisewitz AL. Canine
parvovirus. The Veterinary clinics of
North America Small animal practice
2010;40:1041-1053.
Matjila PT, Carcy B, Leisewitz AL,
et al. Preliminary evaluation of the
BrEMA1 gene as a tool for associating
babesia rossi genotypes and clinical
manifestation of canine Babesiosis.
Journal of clinical microbiology
2009;47:3586-3592.
Leisewitz AL, Rockett K, Kwiatkowski
D. BCG-malaria co-Infection has
paradoxical effects on C57BL/6 and A/J
mouse strains. Parasite immunology
2008;30:1-12.
Leisewitz AL, Rockett KA, Gumede B, et
al. Response of the splenic dendritic cell
population to malaria infection. Infection
and immunity 2004;72:4233-4239.
Andrew Leisewitz graduated with his BVSc degree in 1987. This
was followed by an Hons in 1991, an MMedVet(Med) in 1995 and
a PhD in 2006. Andrew was appointed as a senior lecturer in the
then Departemnt of Medicine at Onderstepoort in June 1990. He is
now full professor of Companion Animal Clinical Studies and is a
diplomat of the European College of Veterinary Internal Medicine –
Companion Animals. He has worked as a specialist clinician in the
Onderstepoort Veterinary Academic Hospital for over 20 years. He
is an active teacher of undergraduate and post graduate veterinary
students, leads the section of Small Animal Medicine within the
Department and is a frequently invited speaker and presenter of
continuing education for the profession in the sub-region.
Research
His interest is in disease mechanisms of infectious diseases.
Particular interests include the use of animal models of human
disease to advance global health. His PhD examined the immune response to blood stage malaria
infection in a murine model system and was completed at the Weatherall Institute for Molecular
Medicine, Oxford. Canine babesiosis
now forms the basis of the majority
of his work. This is a malaria like
disease and in many ways offers
unique modelling opportunities and
comparative pathologies for human
malaria. In addition to this, he has an
interest in the pathogenesis of central
nervous system inflammation and
demyelination as caused by canine
distemper virus infection (which
acts as a model for human multiple
sclerosis). He has also worked on
canine parvo virus induced enteritis
where he has examined the acid
base and gut wall permeability
pathology.
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