Download FINAL EXAMINATION

FINAL EXAMINATION
JANUARY 2012 SEMESTER
1/13/34 ACADEMIC SESSION
COURSE
COURSE CODE
DURATION
FACULTY
PROGRAMME
LECTURER
:
:
:
:
:
CLINICAL MICROBIOLOGY II
MLD 2223
2 HOURS 30 MINUTES
BIOMEDICAL AND HEALTH SCIENCES
DIPLOMA IN MEDICAL LABORATORY
TECHNOLOGY
: MR. MOHD AMIR ABDULLAH
INSTRUCTIONS TO CANDIDATES
This paper consists of three (3) sections:
Section A – 30 questions (multiple choice questions)
Section B – 3 questions (short answer questions)
Section C – 3 questions (essay questions)
Answer all questions in Section A and B and only two (2) questions in Section C.
All answers of:
Section A must be written in OMR objective paper provided.
Section B and C must be written in answer booklet provided.
The answer for each question must start on a new page.
Candidates are NOT ALLOWED to bring any unauthorized items into the exam hall
except with the permission of your invigilator.
Do Not Open the Question Paper Until Instructed
This Question Paper Consists of EIGHT (8) Printed Pages
CONFIDENTIAL
FBHS/MLD2223/JAN2013
SECTION A: OBJECTIVE QUESTIONS
(30 MARKS)
Choose ONE best statement to answer the questions.
1. A symbiotic relationship in which one species benefits from the association while
the other species is harmed from the relationship is called
(A)
(B)
(C)
(D)
parasitism
mutualism
opportunistic
commensalism
2. Which of the following statements about host-microbes is TRUE?
(A)
(B)
(C)
(D)
Bacterimia is presence of virus in the host blood.
A host is any organism that harbors no other organism.
Endemic is a disease that is always present in a population.
In mutualism neither of the two species benefits from the relationship.
3. The study of factors and mechanisms of disease frequency and spread within a
population is called
(A)
(B)
(C)
(D)
endemic
etiology
epidemic
epidemiology
4. Corynebacterium diphtheria can cause
(A)
(B)
(C)
(D)
diphtheria
pharyngitis
tuberculosis
whooping cough
5. Whooping cough is caused by
(A)
(B)
(C)
(D)
Bordetella pertussis
Staphylococcus aureus
Streptococcus pyogenes
Mycobacterium tuberculosis
CONFIDENTIAL/2
FBHS/MLD2223/JAN2013
6.
Which of the following statements about diptheria is INCORRECT?
(A)
(B)
(C)
(D)
Infects the upper respiratory tract
Transmitted by droplets or fomites
The bacteria are Gram-negative rods
Toxin inhibits protein synthesis of cells
7. Pyelonephritis is inflammation of the
(A)
(B)
(C)
(D)
ureter
urethra
urinary bladder
renal parenchyma
8. Classical symptoms of urinary tract infection is characterized by all of the
following EXCEPT
(A)
(B)
(C)
(D)
dysuria
urgency
diarrhea
frequent urination
9. The following organism can cause urinary tract infection EXCEPT
(A)
(B)
(C)
(D)
Bacillus cerues
Escherichia coli
Klebsiella pneumoniae
Pseudomonas aeruginosa
10. Which of the following pair is MISMATCHED?
(A)
(B)
(C)
(D)
Shigella – typhoid fever
enteropathogenic Escherichia coli – traveler's diarrhea
Helicobacter pylori – peptic ulcer and chronic gastritis
Staphylococcus aureus – food poisoning due to enterotoxins A and D
11. Which of the following microbes can cause dysentery?
(A)
(B)
(C)
(D)
Proteus mirabilis
Salmonella enteric
Neisseria gonorrhoeae
Streptococcus pneumoniae
CONFIDENTIAL/3
FBHS/MLD2223/JAN2013
12. All of the following refers to food poisoning EXCEPT
(A)
(B)
(C)
(D)
cystitis can cause due to food poisoning.
Vibrio cholerae infection can cause food poisoning.
the symptom in food poisoning are abdominal cramps and diarrhea.
stool culture is used to diagnosis the microbe involve in food poisoning.
13. Neisseria gonorrhoeae is characterized by all of the following EXCEPT
(A)
(B)
(C)
(D)
cleaves IgA
Gram-negative diplococci
can caused proliferative infections
the symptom of infection are painful urination and purulent discharge
14. Lymphogranuloma venereum is caused by
(A)
(B)
(C)
(D)
Neisseria gonorrhea
Treponema pallidum
Haemophilus ducreyi
Chlamydia trachomatos
15. Which of the following statements about sexually transmitted diseases is FALSE?
(A)
(B)
(C)
(D)
Neisseria gonorrhoeae can cause Gonorrhea
Syphilis cannot be spread from mother to fetus
Young people who experiment with sex are at risk
Papilloma virus can cause proliferative infections
16. Haemophilus ducreyi can cause
(A)
(B)
(C)
(D)
AIDS
hepatitis
chancroid
gonorrhea
17. Waterhouse-Friderichsen syndrome is a complication of
(A)
(B)
(C)
(D)
Bordetella pertussis
Chlamydia trachomatis
Vibrio parahemolyticus
Meningococcal meningitis
CONFIDENTIAL/4
FBHS/MLD2223/JAN2013
18. The MOST COMMON bacteria that cause meningitis in children is
(A)
(B)
(C)
(D)
Clostridium perfringins
Pseudomonas aeruginosa
Streptococcus pneumonia
Calymmatobacterium granulomatosis
19. The following diagnosis are used to detect tuberculous meningitis EXCEPT
(A)
(B)
(C)
(D)
sputum culture
urine examination
tuberculin skin testing
cebro spinal fluid analysis
20. The following are symptoms of meningitis EXCEPT
(A)
(B)
(C)
(D)
jaundice
drowsiness
neck stiffness
sudden high fever
21. Staphylococcus aureus causes all of the following EXCEPT
(A)
(B)
(C)
(D)
impetigo
erysipelas
carbuncles
scalded skin syndrome
24. The following are diseases of bone or joint EXCEPT
(A)
(B)
(C)
(D)
urethritis
osteomyelitis
reactive arthritis
infection of prosthetic joints
25. The following organism can cause haematogenous osteomyelitis EXCEPT
(A)
(B)
(C)
(D)
Salmonella typhi
Staphylococcus aureus
Streptococcus pyogenes
Haemophilus influenzae
CONFIDENTIAL/5
FBHS/MLD2223/JAN2013
26. Which of following diagnosis are use to detect osteomyelitis?
(A)
(B)
(C)
(D)
pus culture
urine examination
feces examination
cerebrospinal fluid analysis
27. The following are laboratory diagnosis acute Septic Arthritis EXCEPT
(A)
(B)
(C)
(D)
ultrasound
plain X-ray
blood culture
feces examination
28. Which of the following definition about a fever of unknown origin (FUO) is
FALSE?
(A)
(B)
(C)
(D)
Deformity with abdominal pain
More than 3 weeks' duration of illness
A temperature greater than 38.3°C (101°F) on several occasions
Failure to reach a diagnosis despite 1 week of patient investigation
29. Fever of unknown origin (FUO) is caused by
(A)
(B)
(C)
(D)
boil
style
neoplasms
acne vulgaris
30. The following bacteria can cause fever of unknown origin (FUO) EXCEPT
(A)
(B)
(C)
(D)
Neisseria meningitidis.
Neisseria gonorrhoeae.
Propionibacter granulosum.
Mycobacterium tuberculosis.
CONFIDENTIAL/6
FBHS/MLD2223/JAN2013
SECTION B: SHORT ANSWER QUESTIONS
(30 MARKS)
Answer ALL questions.
1. a. Differentiate between symptoms and signs.
(4 Marks)
b. Describe the process of disease development.
(6 Marks)
2. a. Define meningitis.
(1 Mark)
b. Name the causal agent for meningococcal meningitis.
(1 Mark)
c. State THREE (3) clinical complications of the meningococcal disease.
(3 Marks)
d. Determine the laboratory diagnosis to detect microbes involved in meningitis.
(5 Marks)
3. a. Describe laboratory diagnosis to detect pathogen that causes septic arthritis.
(5 Marks)
b. Explain the characteristic and types of Escherichia coli.
(5 Marks)
CONFIDENTIAL/7
FBHS/MLD2223/JAN2013
SECTION C: ESSAY QUESTIONS
(40 MARKS)
Answer TWO (2) questions only.
Question 1
Describe about Tuberculosis. Discuss the potential pathogen that causes Tuberculosis,
symptoms, clinical features and related laboratory diagnosis.
(20 Marks)
Question 2
Explain about food poisoning. Discuss the potential pathogens that cause food
poisoning and related laboratory diagnosis.
(20 Marks)
Question 3
Discuss the pathogenesis, signs, symptoms, clinical features and laboratory diagnosis
of syphilis.
(20 Marks)
END OF QUESTION PAPER
CONFIDENTIAL/8